lidocaine and indomethacin

lidocaine has been researched along with indomethacin in 102 studies

Research

Studies (102)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (28.43)	18.7374
1990's	14 (13.73)	18.2507
2000's	31 (30.39)	29.6817
2010's	26 (25.49)	24.3611
2020's	2 (1.96)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Caron, G; Ermondi, G	1
Jolivette, LJ; Ward, KW	1
Jolivette, LJ; Nagilla, R; Ward, KW	1
Carrupt, PA; Martel, S; Ottaviani, G	2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Conradi, R; Lee, PH; Shanmugasundaram, V	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Sen, S; Sinha, N	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Artursson, P; Mateus, A; Matsson, P	1
Bennis, K; Ducki, S; Lesage, F; Vivier, D	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Blake, DE; Holsapple, MP; Yim, GK	1
Fletcher, JR; Ramwell, PW	3
Ferreira, SH; Moncada, S; Vane, JR	1
Håkanson, R; Wallengren, J	1
Bhandare, PN; D'Souza, RS; Dhume, VG; Rataboli, PV	1
Deshpande, YG; Fitzgerald, S; Kaminski, DL; Nguyen, HQ	1
Nebel, U; Wermelskirchen, D; Wilffert, B; Wirth, A	1
Edgar, SW; Greenberg, BH; Perlmutter, NS; Sanders, W; Tanz, R; Wilson, RA	1
Baile, EM; Godden, DJ; Paré, PD	1
Gartner, SL; Shakir, KM; Simpkins, CO; Sobel, DO; Williams, TJ	1
Carey, LC; Castell, DO; Cordova, C; Fletcher, JR; Sinar, DR	1
Brunsson, I	1
Bernstein, PR; Kern, R; Krell, RD; Patterson, R; Smith, LJ	1
Angus, JA; Crabb, DJ; Knight, KR; Niall, M; O'Brien, BM	1
Bentwich, Z; Bibi, H; Eliraz, A; Fink, A; Tabachnik, E	1
Christensen, J; Percy, WH	1
Korth, R; Mangold, HK; Muramatsu, T; Zöllner, N	1
Pozar, B	1
Ball, GV; Freeman, D	1
Abramowitz, MD	1
Sadowska-Wrõblewska, M	1
Bennett, JC; Dodson, WH; McBride, WW	1
Foong, FW; Satoh, M	1
Hillmar, I; Korth, R; Muramatsu, T; Zöllner, N	1
Casey, L; Fletcher, JR; Pomerantz, K; Ramwell, PW	1
Fletcher, JR; Gardiner, M; Jones, SR; Short, BL; Walker, RI	1
Fletcher, JR; Harris, RH; Maddox, Y; Ramwell, PW; Zmudka, M	1
Kivi, P	1
Barron, BA; Kurup, VP; Sheth, NK	1
Zenk, KE	1
Brunsson, I; Cassuto, J; Jodal, M; Lundgren, O; Sjöqvist, A	1
Casey, LC; Fletcher, JR; Ramwell, PC	1
Cho, CH; Ko, JK; Tang, XL	1
Kang, JX; Leaf, A	1
Asakura, N; Inomata, S; Kondo, T; Watanabe, S	1
Holm, L; Jägare, A	1
DiBona, GF; Petersen, JS	1
Dempsey, DT; Mercer, DW; Ritchie, WP	1
Flemström, G; Hällgren, A; Nylander, O	1
Grampp, W; Skogvall, S	1
Al Obaid, AR; Al Rasheed, NM; Al Sayed, MI; Al Zuhair, HH; Fatani, AJ	1
Hällgren, A; Nylander, O; Sababi, M	1
Arslan, S; Celiker, R	1
Aksakal, O; Avşar, F; Parlakyiğit, E; Seçkin, B	1
Barak, M; Katz, Y; Ziser, A	1
Nylander, O; Pihl, L	1
Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Parada, CA; Rocha, FA; Silva, TA; Verri, WA	1
Bozkurt, A; Deniz, M; Kurtel, H	1
Fukami, T; Furuishi, T; Makimura, M; Suzuki, T; Tomono, K; Umeda, Y	1
Cohen, AS	1
Fang, L; He, Z; Xu, Y; Zhao, L; Zhao, Y	1
Fang, L; He, Z; Liu, S; Xu, Y; Zhao, L; Zhao, Y	1
Cohen, AS; Goadsby, PJ	1
Dawidowicz, AL; Kobielski, M; Pieniadz, J	1
Fukami, T; Furuishi, T; Suzuki, T; Tanjoh, K; Tomono, K; Umeda, Y	1
Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR	1
Hakozaki, M; Kikuchi, S; Konno, S; Otani, K; Tajino, T	1
Göbel, C; Göbel, H; Heinze, A	1
Goto, S; Hirabayashi, H; Hirota, K; Shimada, Y; Terada, H; Uchiro, H; Yamaguchi, K	1
Goto, S; Hirota, K; Shimada, Y; Terada, H; Uchiro, H	1
Goto, S; Sagawa, N; Shimada, Y; Tateuchi, R	1
Babaoğlu, B; Guraslan, H; Polat, M; Senturk, MB; Yaşar, L	1
Hattori, T; Hitomi, S; Imai, R; Inenaga, K; Kase, Y; Kubota, K; Omiya, Y; Ono, K; Terawaki, K; Yamaguchi, K	1
Baraldi, C; Cainazzo, MM; Guerzoni, S; Pellesi, L; Pini, LA	1
Campos-Salcedo, JG; Canizalez-Román, A; Parés-Hipólito, J; Sedano-Lozano, A; Shelton, LM; Torres-Gomez, JJ; Valdez-Flores, MA; Valdez-Flores, RA	1
Chen, JC; Chen, JM; Liu, KC; Liu, SJ; Yeh, WL	1
Markowitz, S; Wende, O	1

Reviews

9 review(s) available for lidocaine and indomethacin

Article	Year
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11 Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship	2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Drug therapy in degenerative joint diseases]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1971, Jul-01, Volume: 24, Issue:13 Topics: Animals; Cartilage, Articular; Humans; Hydrocortisone; Indomethacin; Lidocaine; Osteoarthritis; Pyrazoles; Rabbits; Rats; Salicylates; Sulfur Isotopes	1971
An overview of perinatal clinical pharmacology. Clinics in laboratory medicine, 1981, Volume: 1, Issue:2 Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline	1981
Effects of indomethacin suppository and lidocaine pomade for the relief of post-episiotomy pain. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2002, Volume: 78, Issue:2 Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Episiotomy; Female; Humans; Indomethacin; Lidocaine; Pain; Suppositories	2002
[Pathophysiology and treatment of trigeminal autonomic cephalalgias]. Schmerz (Berlin, Germany), 2008, Volume: 22 Suppl 1 Topics: Administration, Oral; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Methysergide; Nociceptors; Oxygen Inhalation Therapy; Paroxysmal Hemicrania; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias; Trigeminal Nerve; Vasoconstrictor Agents; Vasodilator Agents; Verapamil	2008
Pseudogout of the acromioclavicular joint: report of two cases and review of the literature. Modern rheumatology, 2011, Volume: 21, Issue:4 Topics: Acromioclavicular Joint; Aged; Anti-Inflammatory Agents, Non-Steroidal; Calcium Pyrophosphate; Chondrocalcinosis; Dexamethasone; Diclofenac; Drug Therapy, Combination; Glucocorticoids; Humans; Indomethacin; Joint Diseases; Lidocaine; Male; Middle Aged; Synovial Fluid; Tomography, X-Ray Computed	2011
[Paroxysmal hemicrania and SUNCT]. Schmerz (Berlin, Germany), 2011, Volume: 25, Issue:6 Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Child; Cluster Headache; Diagnosis, Differential; Humans; Indomethacin; Lidocaine; Neurologic Examination; Pain Measurement; Paroxysmal Hemicrania; Secondary Prevention; SUNCT Syndrome; Trigeminal Neuralgia	2011
Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal. The journal of headache and pain, 2017, Volume: 18, Issue:1 Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Neuralgia; Paroxysmal Hemicrania; Reproducibility of Results; SUNCT Syndrome; Surveys and Questionnaires; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias	2017

Trials

9 trial(s) available for lidocaine and indomethacin

Article	Year
Mechanism of leukotriene D4-induced bronchoconstriction in normal subject. The Journal of allergy and clinical immunology, 1987, Volume: 80, Issue:3 Pt 1 Topics: Adult; Arachidonic Acids; Atropine; Bronchi; Bronchial Provocation Tests; Constriction, Pathologic; Dose-Response Relationship, Drug; Humans; Indomethacin; Lidocaine; Male; Respiratory Function Tests; SRS-A	1987
The role of analgesia in pulmonary function. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Oct-14, Volume: 46, Issue:41 Topics: Analgesia; Anesthesia, Conduction; Drainage; Hemopneumothorax; Humans; Indomethacin; Lidocaine; Lung; Pneumothorax; Prospective Studies; Spirometry; Vital Capacity	1972
Intraoperative combined administration of indomethacin and buprenorphine suppositories as prophylactic therapy for post-open-cholecystectomy pain. Anesthesia and analgesia, 1994, Volume: 79, Issue:1 Topics: Anesthesia, Epidural; Buprenorphine; Cholecystectomy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Indomethacin; Intraoperative Period; Lidocaine; Male; Middle Aged; Pain, Postoperative; Premedication; Prospective Studies; Suppositories	1994
Comparison of the efficacy of local corticosteroid injection and physical therapy for the treatment of adhesive capsulitis. Rheumatology international, 2001, Volume: 21, Issue:1 Topics: Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Bursitis; Drug Therapy, Combination; Exercise Therapy; Female; Humans; Indomethacin; Injections, Intra-Articular; Lidocaine; Male; Methylprednisolone; Middle Aged; Pain Measurement; Physical Therapy Modalities; Range of Motion, Articular	2001
Thoracic epidural local anesthetics are ineffective in alleviating post-thoracotomy ipsilateral shoulder pain. Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:4 Topics: Analgesia, Epidural; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Intraoperative Period; Lidocaine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Shoulder Pain; Suppositories; Thoracotomy; Treatment Outcome	2004
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing. Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:7 Topics: Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Autonomic Nervous System Diseases; Cohort Studies; Conjunctiva; Cyclohexanecarboxylic Acids; Fructose; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothalamus, Posterior; Indomethacin; Lamotrigine; Lidocaine; Magnetic Resonance Imaging; Oxygen; Pain Measurement; Phenotype; Prospective Studies; SUNCT Syndrome; Tears; Topiramate; Triazines	2007
The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. Journal of endodontics, 2010, Volume: 36, Issue:9 Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Indomethacin; Lidocaine; Male; Mandible; Mandibular Nerve; Molar; Nerve Block; Pain; Pain Measurement; Preanesthetic Medication; Premedication; Prospective Studies; Pulpitis; Root Canal Therapy; Treatment Outcome; Young Adult	2010
The Effect of Intrauterine Lidocaine and Rectal Indomethacin on Pain during Office Vaginoscopic Hysteroscopy: Randomized Double-Blind Controlled Study. Gynecologic and obstetric investigation, 2016, Volume: 81, Issue:3 Topics: Adult; Ambulatory Surgical Procedures; Anesthetics, Local; Double-Blind Method; Endometrial Neoplasms; Female; Humans; Hysteroscopy; Indomethacin; Lidocaine; Middle Aged; Pain; Placebos; Polyps; Rectum; Uterus	2016
Prospective comparison among three intrarectal anesthetic treatments combined with periprostatic nerve block during transrectal ultrasonography-guided prostate biopsy. World journal of urology, 2018, Volume: 36, Issue:2 Topics: Administration, Topical; Aged; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Large-Core Needle; Endosonography; Humans; Image-Guided Biopsy; Indomethacin; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Nerve Block; Pain Measurement; Pain, Procedural; Prilocaine; Prostate; Rectum	2018

Other Studies

84 other study(ies) available for lidocaine and indomethacin

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Identification and prediction of promiscuous aggregating inhibitors among known drugs. Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21 Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship	2003
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2 Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics	2005
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability. Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13 Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water	2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain. Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7 Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Reversible depression of electrically-induced contractions of guinea pig longitudinal muscle by a reversible inhibitor of prostaglandin synthetase. Prostaglandins and medicine, 1979, Volume: 3, Issue:4 Topics: Amidines; Animals; Chlorphenamidine; Clonidine; Cyclooxygenase Inhibitors; Guinea Pigs; Indomethacin; Lidocaine; Morphine; Muscle Contraction; Naloxone; Norepinephrine; Phentolamine; Prostaglandins E; Tolazoline	1979
E. coli endotoxin shock in the dog; treatment with lidocaine or indomethacin. British journal of pharmacology, 1978, Volume: 64, Issue:2 Topics: Animals; Blood Cell Count; Blood Coagulation; Dogs; Endotoxins; Escherichia coli; Hemodynamics; Indomethacin; Lidocaine; Male; Prostaglandins F; Shock, Septic; Time Factors	1978
Lidocaine or indomethacin improves survival in baboon endotoxin shock. The Journal of surgical research, 1978, Volume: 24, Issue:3 Topics: Animals; Dogs; Haplorhini; Hemodynamics; Indomethacin; Lidocaine; Male; Papio; Prostaglandins F; Shock, Septic	1978
E. coli endotoxin shock in the baboon: treatment with lidocaine or indomethacin. Advances in prostaglandin and thromboxane research, 1978, Volume: 3 Topics: Animals; Blood Pressure; Cardiac Output; Escherichia coli; Haplorhini; Heart Rate; Indomethacin; Lidocaine; Male; Papio; Prostaglandins F; Shock, Septic	1978
Inhibition of prostaglandin biosynthesis as the mechanism of analgesia of aspirin-like drugs in the dog knee joint. European journal of pharmacology, 1975, Volume: 31, Issue:2 Topics: Analgesia; Animals; Aspirin; Blood Pressure; Bradykinin; Carrageenan; Depression, Chemical; Dogs; Female; Indomethacin; Inflammation; Knee Joint; Lidocaine; Male; Prostaglandins; Prostaglandins E; Reflex	1975
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin. The British journal of dermatology, 1992, Volume: 126, Issue:2 Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation	1992
Protective effect of propranolol on ethanol-induced gastric lesions in rats: probable mechanism of action. Indian journal of physiology and pharmacology, 1992, Volume: 36, Issue:1 Topics: Animals; Drug Interactions; Ethanol; Gastric Fundus; Gastrointestinal Hemorrhage; Indomethacin; Lidocaine; Male; Methylene Blue; Muscle Contraction; Propranolol; Rats; Rats, Inbred Strains; Stomach Diseases	1992
The effect of capsaicin on gallbladder fluid absorption. Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:4 Pt 1 Topics: Absorption; Animals; Body Fluids; Buffers; Capsaicin; Cats; Gallbladder; Indomethacin; Lidocaine; Osmolar Concentration; Perfusion; Prostaglandins	1991
45Ca2+ movements induced by Ca2+ chloride in isolated rat aorta under K(+)-free conditions. European journal of pharmacology, 1991, Jan-17, Volume: 192, Issue:3 Topics: Amiloride; Animals; Aorta, Thoracic; Benzothiazoles; Calcium; Calcium Chloride; Calcium Radioisotopes; Flunarizine; In Vitro Techniques; Indomethacin; Lanthanum; Lidocaine; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Piperidines; Potassium; Rats; Thiazoles; Vasoconstriction	1991
Vasodilatory effects of lidocaine on epicardial porcine coronary arteries. Pharmacology, 1990, Volume: 41, Issue:5 Topics: Animals; Coronary Vessels; Female; In Vitro Techniques; Indomethacin; Lidocaine; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Propranolol; Swine; Vasodilator Agents	1990
Mechanism for increase in tracheobronchial blood flow induced by hyperventilation of dry air in dogs. Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 68, Issue:1 Topics: Animals; Bronchi; Dogs; Humidity; Hyperventilation; Indomethacin; Lidocaine; Pulmonary Circulation; Temperature; Trachea	1990
Phospholipase C activity in human polymorphonuclear leukocytes: partial characterization and effect of indomethacin. Enzyme, 1989, Volume: 42, Issue:4 Topics: Calcium; Deoxycholic Acid; Fatty Acids, Nonesterified; Humans; Indomethacin; Kinetics; Lidocaine; Naloxone; Neutrophils; Quinacrine; Type C Phospholipases	1989
Lidocaine inhibition of esophageal peristalsis and lower esophageal sphincter pressure in baboons. Digestive diseases and sciences, 1985, Volume: 30, Issue:11 Topics: Animals; Bethanechol; Bethanechol Compounds; Esophagogastric Junction; Esophagus; Indomethacin; Infusions, Parenteral; Lidocaine; Male; Muscle, Smooth; Papio; Peristalsis; Premedication; Pressure	1985
Enteric nerves mediate the fluid secretory response due to Salmonella typhimurium R5 infection in the rat small intestine. Acta physiologica Scandinavica, 1987, Volume: 131, Issue:4 Topics: Animals; Atropine; Enteritis; Hexamethonium; Hexamethonium Compounds; Ileum; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Jejunum; Lidocaine; Male; Rats; Rats, Inbred Strains; Salmonella Infections, Animal; Salmonella typhimurium	1987
Topical use of prostacyclin in microvascular surgery. British journal of plastic surgery, 1985, Volume: 38, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Dose-Response Relationship, Drug; Epoprostenol; Femoral Artery; Indomethacin; Lidocaine; Microcirculation; Microsurgery; Platelet Aggregation; Rabbits; Regional Blood Flow; Surgical Flaps; Vasodilation	1985
Leukotrienes (LTC4, LTD4) confer glass non-adherence on leukocytes of asthmatic individuals. Dependency on cyclooxygenase products and calcium ion. Immunology letters, 1985, Volume: 10, Issue:6 Topics: Asthma; Calcium; Cell Adhesion; Child; Cyclooxygenase Inhibitors; Dinoprostone; Glass; Humans; Indomethacin; Lanthanum; Leukocyte Adherence Inhibition Test; Leukocytes; Lidocaine; Nifedipine; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; SRS-A; Trifluoperazine	1985
Pharmacological characterization of opossum distal colonic muscularis mucosae in vitro. The American journal of physiology, 1986, Volume: 250, Issue:1 Pt 1 Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atropine; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Female; Histamine; In Vitro Techniques; Indomethacin; Lidocaine; Male; Muscle Contraction; Muscles; Norepinephrine; Opossums; Phentolamine; Propranolol; Pyrilamine; Tetrodotoxin	1986
Unsaturated 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholines (unsaturated platelet-activating factor): aggregation of human platelets after incubation with indomethacin, creatinephosphate/creatinephosphokinase, xylocain and hirudine, and serotonin release Chemistry and physics of lipids, 1985, Volume: 36, Issue:3 Topics: Blood Platelets; Creatine Kinase; Female; Hirudins; Humans; Indomethacin; Lidocaine; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Serotonin	1985
[Acute painful shoulder syndrome]. Reumatizam, 1970, Volume: 17, Issue:4 Topics: Administration, Topical; Adolescent; Adult; Age Factors; Aged; Analgesics; Anti-Inflammatory Agents; Female; Humans; Hydrocortisone; Indomethacin; Lidocaine; Male; Middle Aged; Prednisone; Reflex Sympathetic Dystrophy	1970
Management of chronic and recurrent gout. Modern treatment, 1971, Volume: 8, Issue:4 Topics: Adrenocorticotropic Hormone; Allopurinol; Chronic Disease; Colchicine; Dexamethasone; Diet Therapy; Gout; Humans; Indomethacin; Lidocaine; Phenylbutazone; Prednisolone; Probenecid; Recurrence; Synovial Fluid; Uric Acid	1971
Management of rheumatoid arthritis. Southern medical journal, 1969, Volume: 62, Issue:3 Topics: Adrenal Cortex Hormones; Amitriptyline; Anxiety; Arthritis, Rheumatoid; Aspirin; Attitude of Health Personnel; Barbiturates; Chlordiazepoxide; Chloroquine; Exercise Therapy; Gold; Hospitalization; Hot Temperature; Humans; Indomethacin; Injections, Intra-Articular; Lidocaine; Mechlorethamine; Phenylbutazone; Physical Therapy Modalities; Physician-Patient Relations; Prednisolone; Rest	1969
Analgesic potencies of non-narcotic, narcotic and anesthetic drugs as determined by the bradykinin-induced biting-like responses in rats. Japanese journal of pharmacology, 1983, Volume: 33, Issue:5 Topics: Analgesics; Analgesics, Opioid; Anesthetics; Animals; Baclofen; Bradykinin; Chloralose; Dose-Response Relationship, Drug; Indomethacin; Lidocaine; Male; Morphine; Nociceptors; Rats; Rats, Inbred Strains	1983
1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholines: influence on aggregation and [3H]serotonin release of human thrombocytes. Chemistry and physics of lipids, 1983, Volume: 33, Issue:1 Topics: Blood Platelets; Hirudins; Humans; Indomethacin; Kinetics; Lidocaine; Phosphocreatine; Platelet Activating Factor; Platelet Aggregation; Serotonin	1983
Vascular reactivity in endotoxin shock: effect of lidocaine or indomethacin pretreatment. Advances in shock research, 1982, Volume: 7 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; In Vitro Techniques; Indomethacin; Lidocaine; Male; Norepinephrine; Prostaglandin Endoperoxides, Synthetic; Rats; Shock, Septic; Vasoconstriction	1982
Indomethacin improves survival in gram-negative sepsis. Advances in shock research, 1981, Volume: 6 Topics: Animals; Blood Pressure; Disease Models, Animal; Escherichia coli Infections; Indomethacin; Leukocyte Count; Lidocaine; Male; Peritonitis; Platelet Count; Rats; Rats, Inbred Strains; Shock, Septic	1981
Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. Advances in prostaglandin and thromboxane research, 1980, Volume: 7 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arteries; Blood Pressure; Haplorhini; Indomethacin; Lidocaine; Papio; Prostaglandins F; Shock, Septic; Thromboxane B2; Thromboxanes	1980
The etiology and conservative treatment of humeral epicondylitis. Scandinavian journal of rehabilitation medicine, 1983, Volume: 15, Issue:1 Topics: Adult; Athletic Injuries; Betamethasone; Female; Forearm Injuries; Humans; Indomethacin; Lidocaine; Male; Methylprednisolone; Middle Aged; Prospective Studies; Splints; Tennis Elbow	1983
The role of Aspergillus fumigatus antigens in blood coagulation and platelet function. Microbios, 1980, Volume: 28, Issue:112 Topics: Animals; Antigens, Fungal; Aspergillus fumigatus; Aspirin; Blood Coagulation; Indomethacin; Lidocaine; Platelet Aggregation; Rabbits	1980
The effect of intestinal fluid transport of exposing the serosa to hydrochloric acid. A study of mechanisms. Acta physiologica Scandinavica, 1982, Volume: 116, Issue:4 Topics: Animals; Atropine; Cats; Female; Hexamethonium Compounds; Hydrochloric Acid; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Jejunum; Lidocaine; Male; Rats; Rats, Inbred Strains; Tetrodotoxin	1982
The protective effect of lidocaine on arachidonate metabolism in septic shock. Progress in lipid research, 1981, Volume: 20 Topics: Animals; Arachidonic Acids; Dogs; Humans; Indomethacin; Lidocaine; Papio; Prostaglandins; Rats; Shock, Septic	1981
The differential mechanisms of mild irritants on adaptive cytoprotection. Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1 Topics: Adaptation, Physiological; Animals; Arginine; Atropine; Capsaicin; Chorionic Gonadotropin; Ethanol; Gastric Mucosa; Hexamethonium; Indomethacin; Irritants; Lidocaine; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach Ulcer; Substance P	1994
Effects of long-chain polyunsaturated fatty acids on the contraction of neonatal rat cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21 Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Animals, Newborn; Arachidonic Acid; Calcium; Cells, Cultured; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fish Oils; Heart; Indomethacin; Lidocaine; Myocardial Contraction; Ouabain; Rats; Serum Albumin, Bovine; Structure-Activity Relationship	1994
Influence of tactile stimulation of the rat gastric mucosa on blood flow and acid output. The American journal of physiology, 1993, Volume: 265, Issue:2 Pt 1 Topics: Animals; Gastric Acid; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; Indomethacin; Laser-Doppler Flowmetry; Lidocaine; Male; Methysergide; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow	1993
Furosemide elicits nonuniform reflex responses via cardiac sympathetic afferents. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 2 Topics: Animals; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Furosemide; Heart Conduction System; Indomethacin; Injections; Lidocaine; Male; Neurons, Afferent; Pericardium; Rats; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System; Vagotomy	1994
Sensory neuron-mediated gastric mucosal protection is blocked by cyclooxygenase inhibition. Surgery, 1994, Volume: 115, Issue:2 Topics: Administration, Topical; Animals; Bile Acids and Salts; Capsaicin; Cyclooxygenase Inhibitors; DNA; Gastric Mucosa; Indomethacin; Lidocaine; Nerve Block; Neurons, Afferent; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Taurocholic Acid	1994
Interaction between neurokinin A, VIP, prostanoids, and enteric nerves in regulation of duodenal function. The American journal of physiology, 1998, Volume: 275, Issue:1 Topics: Analysis of Variance; Animals; Bicarbonates; Chromium Radioisotopes; Duodenum; Edetic Acid; Gastrointestinal Motility; Indomethacin; Infusions, Intravenous; Intestinal Absorption; Intestinal Mucosa; Lidocaine; Male; Metabolic Clearance Rate; Muscle, Smooth; Neurokinin A; Neurons; Pressure; Prostaglandins; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasoactive Intestinal Peptide	1998
Physiological oxygen concentration gives an oscillating spontaneous tone in guinea-pig tracheal preparations. Acta physiologica Scandinavica, 1999, Volume: 165, Issue:1 Topics: Animals; Capsaicin; Electric Stimulation; Guinea Pigs; Heptanol; In Vitro Techniques; Indomethacin; Lidocaine; Male; Muscle Tonus; Muscle, Smooth; Oscillometry; Oxygen; Tetrodotoxin; Trachea	1999
Effects of two newly synthesized analogues of lidocaine on rat arterial blood pressure and heart rate. Pharmacological research, 2001, Volume: 43, Issue:4 Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atropine; Benzoates; Blood Pressure; Calcium Chloride; Cyproheptadine; Enzyme Inhibitors; Heart Rate; Hexamethonium; Histamine Agonists; Indomethacin; Lidocaine; Male; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Pyrilamine; Quinacrine; Ranitidine; Rats; Rats, Wistar; Vasodilator Agents	2001
COX inhibition excites enteric nerves that affect motility, alkaline secretion, and permeability in rat duodenum. American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:5 Topics: Alkalies; Animals; Cyclooxygenase Inhibitors; Duodenum; Enteric Nervous System; Gastrointestinal Motility; Iloprost; Indomethacin; Intestinal Mucosa; Lidocaine; Male; Permeability; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Regional Blood Flow; Serous Membrane	2001
Luminal hypotonicity increases duodenal mucosal permeability by a mechanism involving 5-hydroxytryptamine. Acta physiologica (Oxford, England), 2006, Volume: 186, Issue:1 Topics: Anesthetics, Local; Animals; Cyclooxygenase Inhibitors; Duodenum; Granisetron; Indoles; Indomethacin; Intestinal Mucosa; Lidocaine; Male; Ondansetron; Osmotic Pressure; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Agents; Serotonin Antagonists; Tetrodotoxin; Tropisetron	2006
Hypernociception elicited by tibio-tarsal joint flexion in mice: a novel experimental arthritis model for pharmacological screening. Pharmacology, biochemistry, and behavior, 2006, Volume: 84, Issue:2 Topics: Animals; Arthritis; Behavior, Animal; Cyclooxygenase Inhibitors; Hindlimb; Indomethacin; Lidocaine; Male; Mice; Mice, Inbred C57BL; Morphine; Pain Measurement; Pressure; Tarsal Joints; Zymosan	2006
Mediators of glucagon-like peptide 2-induced blood flow: responses in different vascular sites. Regulatory peptides, 2007, Jul-05, Volume: 142, Issue:1-2 Topics: Animals; Atropine; Benzodiazepinones; Blood Flow Velocity; Blood Vessels; Devazepide; Female; Glucagon-Like Peptide 2; Hormone Antagonists; Indomethacin; Infusions, Intravenous; Lidocaine; Male; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Peptide Fragments; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Time Factors	2007
Molecular complex consisting of two typical external medicines: intermolecular interaction between indomethacin and lidocaine. Chemical & pharmaceutical bulletin, 2007, Volume: 55, Issue:5 Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Indomethacin; Lidocaine; Magnetic Resonance Spectroscopy; Microscopy, Polarization; Models, Molecular; Solubility; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Thermogravimetry	2007
Effect of O-acylmenthol on transdermal delivery of drugs with different lipophilicity. International journal of pharmaceutics, 2008, Mar-20, Volume: 352, Issue:1-2 Topics: Acids, Carbocyclic; Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Cinnamates; Diffusion Chambers, Culture; Drug Compounding; Fluorouracil; Hydrolysis; Indomethacin; Isosorbide Dinitrate; Ketoprofen; Kinetics; Lactates; Lidocaine; Male; Menthol; Oleic Acids; Permeability; Pharmaceutical Preparations; Rats; Rats, Wistar; Salicylates; Skin; Skin Absorption; Technology, Pharmaceutical	2008
Transdermal delivery of penetrants with differing lipophilicities using O-acylmenthol derivatives as penetration enhancers. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 69, Issue:1 Topics: Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Fatty Acids; Fluorouracil; Indomethacin; Isosorbide Dinitrate; Ketoprofen; Lidocaine; Male; Menthol; Rats; Rats, Wistar; Skin Absorption; Technology, Pharmaceutical	2008
Anomalous relationship between free drug fraction and its total concentration in drug-protein systems II. Binding of different ligands to plasma proteins. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Sep-02, Volume: 35, Issue:1-2 Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Gas Chromatography-Mass Spectrometry; Humans; Indomethacin; Lidocaine; Ligands; Orosomucoid; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Suspensions	2008
Characterization of multicomponent crystal formed between indomethacin and lidocaine. Drug development and industrial pharmacy, 2009, Volume: 35, Issue:7 Topics: Crystallization; Crystallography, X-Ray; Indomethacin; Lidocaine; Powders; X-Ray Diffraction	2009
Features of heat-induced amorphous complex between indomethacin and lidocaine. Colloids and surfaces. B, Biointerfaces, 2013, Feb-01, Volume: 102 Topics: Calorimetry; Calorimetry, Differential Scanning; Hot Temperature; Indomethacin; Lidocaine; Magnetic Resonance Spectroscopy	2013
Characteristics of amorphous complex formed between indomethacin and lidocaine hydrochloride. Colloids and surfaces. B, Biointerfaces, 2013, May-01, Volume: 105 Topics: Calorimetry, Differential Scanning; Glass; Hot Temperature; Indomethacin; Lidocaine; Magnetic Resonance Spectroscopy; Phase Transition; Rubber	2013
Enhancement of the 1-Octanol/Water Partition Coefficient of the Anti-Inflammatory Indomethacin in the Presence of Lidocaine and Other Local Anesthetics. The journal of physical chemistry. B, 2015, Jul-30, Volume: 119, Issue:30 Topics: 1-Octanol; Anesthetics, Local; Anti-Inflammatory Agents; Entropy; Indomethacin; Lidocaine; Water	2015
The traditional Japanese medicine hangeshashinto alleviates oral ulcer-induced pain in a rat model. Archives of oral biology, 2016, Volume: 66 Topics: Acetic Acid; Administration, Topical; Analgesics; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Hypersensitivity; Indomethacin; Japan; Lidocaine; Male; Mouth Mucosa; Mouthwashes; Oral Ulcer; Pain; Random Allocation; Rats; Rats, Wistar; Stomatitis	2016
Sustained Release of Levobupivacaine, Lidocaine, and Acemetacin from Electrosprayed Microparticles: In Vitro and In Vivo Studies. International journal of molecular sciences, 2020, Feb-06, Volume: 21, Issue:3 Topics: 3T3 Cells; Analgesics; Animals; Delayed-Action Preparations; Disease Models, Animal; Drug Compounding; Femoral Fractures; Fractures, Bone; Indomethacin; Levobupivacaine; Lidocaine; Mice; Microtechnology; Molecular Structure; Pain; Particle Size; Rats; Spectrometry, Mass, Electrospray Ionization	2020
Headache from clinically confirmed hemicrania continua arising from the sternocleidomastoid muscle: a case report. BMC neurology, 2021, May-03, Volume: 21, Issue:1 Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Humans; Indomethacin; Lidocaine; Male; Neck Muscles; Pain, Referred; Trigeminal Autonomic Cephalalgias	2021