lidocaine has been researched along with glutamic acid in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (8.82) | 18.7374 |
| 1990's | 15 (22.06) | 18.2507 |
| 2000's | 35 (51.47) | 29.6817 |
| 2010's | 10 (14.71) | 24.3611 |
| 2020's | 2 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Follett, KA; Gebhart, GF | 1 |
| Liu, B; Liu, M; Liu, X | 1 |
| Balázs, R; Gallo, V; Jørgensen, OS; Kingsbury, A | 1 |
| Gebhart, GF; Janss, AJ | 1 |
| Sapru, HN; Urbanski, RW | 1 |
| Liu, GJ; Wang, S | 2 |
| Carlen, PL; Puil, E | 1 |
| McLean, HA; Perry, SF; Remmers, JE | 1 |
| Wang, W; Xu, M; Zheng, Y | 1 |
| Chouvet, G; Gonon, FG; Grenhoff, J; Murase, S; Svensson, TH | 1 |
| Sluka, KA; Westlund, KN | 1 |
| Biella, G; Sotgiu, ML | 1 |
| Berger, TW; Grace, AA; Nisenbaum, ES | 1 |
| Borosky, S; Marcoux, FW; Probert, AW; Taylor, CP | 1 |
| Grünschlag, CR; Haas, HL; Stevens, DR | 1 |
| Cairns, BE; Hu, JW; Sessle, BJ | 2 |
| de Curtis, M; Forti, M; Radici, C | 1 |
| Lipton, P; Zhang, Y | 1 |
| Alessandri, N; Brunelle, G; Champeroux, P; Gola, M; Hamon, J; Lanet, S; Maurin, A; Richard, S; Roman, FJ | 1 |
| Bardgett, ME; Henry, JD | 1 |
| Lerma, J; López-García, JC; Rodríguez-Moreno, A | 1 |
| Lawand, NB; McNearney, T; Westlund, KN | 1 |
| Kirouac, GJ; Pittman, QJ | 1 |
| Faganello, FA; Prado, WA | 1 |
| Agababov, V; Lenarz, T; Wilhelm, T | 1 |
| Behbehani, MM; Jiang, M | 1 |
| Biró, Z; Grillner, S; Hill, RH; Hu, GY | 1 |
| Carobrez, AP; De Lima, TC; Lino-de-Oliveira, C | 1 |
| Stanford, IM | 1 |
| Itoh, M; Kawai, K; Matsumoto, M; Matsumoto, S; Sakabe, T; Yamashita, A | 1 |
| Fang, H; Huang, Y; Lim, YJ; Zuo, Z | 1 |
| Andrade, R; Béïque, JC; Chapin-Penick, EM; Mladenovic, L | 1 |
| Heermann, R; Lenarz, T; Schwab, B | 1 |
| Dudley, SC; Fozzard, HA; Glaaser, I; Hilber, K; Sandtner, W; Szendroedi, J; Todt, H; Zarrabi, T; Zebedin, E | 1 |
| Francis, NN; Kantrowitz, JT; Perkins, KL; Salah, A | 1 |
| Barnes, NY; Parent, AT; Sisodia, SS; Taniguchi, Y; Thinakaran, G | 1 |
| Favorov, OV; Lee, J; Tommerdahl, M; Whitsel, BL | 1 |
| Corrêa, FM; Pajolla, GP; Pelosi, GG; Tavares, RF | 1 |
| Cao, P; Wang, SR; Yang, Y | 1 |
| Binshtok, AM; Fleidervish, IA; Gutnick, MJ; Sprengel, R | 1 |
| Ishizuka, K; Murakami, T; Oskutyte, D; Satoh, Y | 1 |
| Graeme Shaw, D; Hoang, BX; Hoang, C; Levine, SA; Pham, P | 1 |
| Arab, HA; Cheung, K; Hickman, PE; Kadkhodaee, M; Potter, JM; Roberts, MS | 1 |
| Edgerton, GB; Fozzard, HA; Hanck, DA; Lipkind, GM; McNulty, MM; Shah, RD | 1 |
| Chen, AD; De, W; Duan, YC; Gao, XY; Xu, B; Zhong, MK; Zhu, GQ | 1 |
| Kitano, H; Shinohara, H; Zakir Hossain, SM | 1 |
| Abraini, JH; David, HN; Rouillon, C | 1 |
| Basu, AC; Benneyworth, MA; Bergeron, R; Coyle, JT; Ehmsen, JT; Froimowitz, MP; Han, L; Jiang, ZI; Lange, N; Ma, CL; Mustafa, AK; Snyder, SH; Tsai, GE | 1 |
| Han, AL; Liu, XL; Liu, XM; Mei, Z; Wang, DF; Wu, CL | 1 |
| Fujita, T; Jiang, CY; Kumamoto, E; Liu, T; Nakatsuka, T; Piao, LH; Yue, HY | 1 |
| Lauwers, MH; Michotte, Y; Poelaert, J; Shi, L; Smolders, I; Umbrain, VJ | 1 |
| Goyagi, T; Masaki, Y; Nishikawa, T; Tobe, Y | 1 |
| Bolshakov, VY; Kang, JS; Krupa, B; Li, Y; Liu, G | 1 |
| Basile, L; Pignatello, R; Puglisi, G | 1 |
| Chung, CC; MacLeod, BA; Ries, CR; Schwarz, SK; Wang, JT; Whitehead, RA | 1 |
| Adachi, M; Bal, M; Kavalali, ET; Monteggia, LM; Sara, Y | 1 |
| Chung, CY; Huang, SK; Lin, TY; Lu, CW; Shieh, JS; Wang, SJ | 1 |
| Arendt-Nielsen, L; Cairns, BE; Dong, XD; Gazerani, P; Kumar, U; Laursen, JC; Somvanshi, RK | 1 |
| Almeida, A; Amorim, D; Pertovaara, A; Pinto-Ribeiro, F; Viisanen, H; Wei, H | 1 |
| Furue, H; Kohno, T; Kurabe, M | 1 |
| Boccella, S; de Novellis, V; Farina, A; Guida, F; Iannotta, M; Luongo, L; Maione, S; Marabese, I; Palazzo, E; Serra, N | 1 |
| She, Y; Song, X; Xu, H; Zhao, B | 1 |
| Cantet, RJC; Laurella, SL; Nishida, F; Portiansky, EL; Sisti, MS; Zanuzzi, CN | 1 |
| Feng, Y; Liu, J; Zhang, WS | 1 |
| Chang, P; Feng, Y; Kang, Y; Li, CY; Liao, P; Liu, J; Zhang, WS | 1 |
2 trial(s) available for lidocaine and glutamic acid
| Article | Year |
|---|---|
[Use of the round window micro cath for inner ear therapy - results of a placebo-controlled, prospective study on chronic tinnitus].
Topics: Administration, Topical; Adult; Aged; Auditory Threshold; Catheters, Indwelling; Chronic Disease; Ear, Inner; Endoscopy; Female; Glutamic Acid; Humans; Infusion Pumps; Lidocaine; Loudness Perception; Male; Middle Aged; Pain Measurement; Patient Satisfaction; Quinoxalines; Round Window, Ear; Tinnitus; Treatment Outcome | 2004 |
Chitosan glutamate hydrogels with local anesthetic activity for buccal application.
Topics: Administration, Buccal; Adult; Anesthesia, Local; Anesthetics, Local; Anti-Infective Agents, Local; Biocompatible Materials; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Stability; Female; Glutamic Acid; Humans; Hydrogels; Lidocaine; Male; Mouth Mucosa; Technology, Pharmaceutical | 2009 |
66 other study(ies) available for lidocaine and glutamic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Modulation of cortical evoked potentials by stimulation of nucleus raphe magnus in rats.
Topics: Animals; Cerebral Cortex; Electric Stimulation; Electroshock; Evoked Potentials; Evoked Potentials, Visual; Functional Laterality; Glutamates; Glutamic Acid; Hindlimb; Lidocaine; Male; Microinjections; Raphe Nuclei; Rats; Rats, Inbred Strains; Reference Values; Sodium Glutamate; Thalamus | 1992 |
[The analgesic effect of red nucleus and strengthening effect thereof to the acupuncture analgesia].
Topics: Acupuncture Analgesia; Animals; Electroacupuncture; Evoked Potentials; Glutamates; Glutamic Acid; Lidocaine; Neurons; Nociceptors; Raphe Nuclei; Rats; Red Nucleus | 1991 |
The role of depolarization in the survival and differentiation of cerebellar granule cells in culture.
Topics: Animals; Antigens, Surface; Calcium; Calcium Channel Blockers; Cell Adhesion; Cell Adhesion Molecules; Cell Count; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellum; DNA; Glutamates; Glutamic Acid; Lidocaine; Membrane Potentials; Potassium; Rats; Tetrodotoxin | 1987 |
Brainstem and spinal pathways mediating descending inhibition from the medullary lateral reticular nucleus in the rat.
Topics: Animals; Brain; Brain Stem; Cerebral Ventricles; Electric Stimulation; Functional Laterality; Glutamates; Glutamic Acid; Lidocaine; Male; Medulla Oblongata; Microinjections; Pain Measurement; Rats; Rats, Inbred Strains; Spinal Cord | 1988 |
Evidence for a sympathoexcitatory pathway from the nucleus tractus solitarii to the ventrolateral medullary pressor area.
Topics: Animals; Blood Pressure; Brain Mapping; Diffusion; Glutamates; Glutamic Acid; Lidocaine; Male; Medulla Oblongata; Muscimol; Neural Pathways; Neurons; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sympathetic Nervous System | 1988 |
[Effects of nucleus raphe magnus and locus coeruleus in descending modulation of the habenula on pain threshold and acupuncture analgesia].
Topics: Acupuncture Therapy; Analgesia; Animals; Efferent Pathways; Electric Stimulation; Female; Glutamates; Glutamic Acid; Lidocaine; Locus Coeruleus; Male; Pain; Raphe Nuclei; Rats; Sensory Thresholds; Thalamic Nuclei | 1988 |
[The influence of blocking habenulae or medial forebrain bundles on the analgesic effect elicited by administration L-glutamic acid into the septa].
Topics: Analgesia; Animals; Female; Glutamates; Glutamic Acid; Lidocaine; Male; Medial Forebrain Bundle; Neural Pathways; Pain; Rats; Sensory Thresholds; Septal Nuclei; Thalamic Nuclei | 1988 |
Attenuation of glutamate-action, excitatory postsynaptic potentials, and spikes by intracellular QX 222 in hippocampal neurons.
Topics: Action Potentials; Animals; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Lidocaine; Membrane Potentials; Neurons; Synapses | 1984 |
Two regions in the isolated brainstem of the frog that modulate respiratory-related activity.
Topics: Animals; Brain Stem; Cranial Nerves; Decerebrate State; Female; gamma-Aminobutyric Acid; Glossopharyngeal Nerve; Glutamic Acid; In Vitro Techniques; Lidocaine; Male; Motor Neurons; Rana catesbeiana; Respiratory Mechanics; Reticular Formation | 1995 |
[Effect of microinjection of lidocaine and L-glutamate into the nucleus paragigantocellularis lateralis on the respiration and arterial blood pressure in the rat].
Topics: Animals; Blood Pressure; Female; Glutamic Acid; Lidocaine; Male; Medulla Oblongata; Microinjections; Neurons; Rats; Rats, Sprague-Dawley; Respiration | 1994 |
Prefrontal cortex regulates burst firing and transmitter release in rat mesolimbic dopamine neurons studied in vivo.
Topics: Animals; Electrophysiology; Glutamates; Glutamic Acid; Lidocaine; Limbic System; Male; Microinjections; Nerve Endings; Neurons; Neurotransmitter Agents; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 1993 |
Spinal cord amino acid release and content in an arthritis model: the effects of pretreatment with non-NMDA, NMDA, and NK1 receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Arthritis; Biphenyl Compounds; Disease Models, Animal; Glutamates; Glutamic Acid; Immunohistochemistry; Lidocaine; Male; Microdialysis; Neurokinin-1 Receptor Antagonists; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Central effects of systemic lidocaine mediated by glycine spinal receptors: an iontophoretic study in the rat spinal cord.
Topics: Animals; Glutamates; Glutamic Acid; Injections, Intravenous; Iontophoresis; Lidocaine; Male; Neurons; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine; Time Factors | 1993 |
Depression of glutamatergic and GABAergic synaptic responses in striatal spiny neurons by stimulation of presynaptic GABAB receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Corpus Striatum; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Lidocaine; Male; Neurons; Pregnanolone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Sodium Channel Blockers; Synapses | 1993 |
Sodium channel modulators prevent oxygen and glucose deprivation injury and glutamate release in rat neocortical cultures.
Topics: Animals; Calcium; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Glucose; Glutamic Acid; L-Lactate Dehydrogenase; Lidocaine; Neurons; Phenytoin; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin | 1997 |
5-HT inhibits lateral entorhinal cortical neurons of the rat in vitro by activation of potassium channel-coupled 5-HT1A receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthetics, Local; Animals; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Lidocaine; Lysine; Male; Neural Inhibition; Neurons; Perforant Pathway; Potassium; Potassium Channels; Propranolol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sympatholytics | 1997 |
Evidence that excitatory amino acid receptors within the temporomandibular joint region are involved in the reflex activation of the jaw muscles.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Brain Stem; Dose-Response Relationship, Drug; Electromyography; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Jaw; Kainic Acid; Lidocaine; Male; Masseter Muscle; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Trigeminal Nerve | 1998 |
Cellular mechanisms underlying spontaneous interictal spikes in an acute model of focal cortical epileptogenesis.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Acute Disease; Animals; Bicuculline; Brain; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; Functional Laterality; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Lidocaine; Membrane Potentials; Reaction Time; Synaptic Transmission | 1999 |
Cytosolic Ca2+ changes during in vitro ischemia in rat hippocampal slices: major roles for glutamate and Na+-dependent Ca2+ release from mitochondria.
Topics: Animals; Calcium; Cytosol; Dizocilpine Maleate; Glutamic Acid; Hippocampus; In Vitro Techniques; Ischemic Attack, Transient; Kinetics; Lidocaine; Male; Mitochondria; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Calcium Exchanger; Time Factors | 1999 |
Pharmacological properties of trimebutine and N-monodesmethyltrimebutine.
Topics: Animals; Batrachotoxins; Binding, Competitive; Cell Line; Cells, Cultured; Cerebral Cortex; Cornea; Embryo, Mammalian; Embryo, Nonmammalian; Female; Ganglia, Spinal; Glutamic Acid; Humans; In Vitro Techniques; Intracellular Membranes; Kv1.1 Potassium Channel; Kv1.2 Potassium Channel; Lidocaine; Male; Membrane Potentials; Neurons; Oocytes; Potassium Channels; Potassium Channels, Voltage-Gated; Rabbits; Rats; Rats, Sprague-Dawley; Spinal Cord; Stereoisomerism; Synaptosomes; Trimebutine; Xenopus laevis | 1999 |
Locomotor activity and accumbens Fos expression driven by ventral hippocampal stimulation require D1 and D2 receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Benzazepines; Brain Chemistry; Cycloleucine; Dextroamphetamine; Dopamine Agents; Dopamine Antagonists; Excitatory Amino Acid Agonists; Genes, Immediate-Early; Glutamic Acid; Haloperidol; Hippocampus; Kainic Acid; Lidocaine; Locomotion; Male; N-Methylaspartate; Neural Pathways; Neuroprotective Agents; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1999 |
Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Bicuculline; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Indoles; Interneurons; Isoxazoles; Kainic Acid; Lidocaine; Maleimides; Naphthalenes; Nerve Tissue Proteins; Patch-Clamp Techniques; Propionates; Protein Kinase C; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Kainic Acid; Receptors, Presynaptic; Signal Transduction; Staurosporine; Virulence Factors, Bordetella | 2000 |
Amino acid release into the knee joint: key role in nociception and inflammation.
Topics: Amino Acids; Anesthetics, Local; Animals; Arginine; Arthritis; Carrageenan; Chromatography, High Pressure Liquid; Citrulline; Glutamic Acid; Hindlimb; Injections, Intra-Articular; Joints; Kaolin; Lidocaine; Male; Pain; Rats; Rats, Sprague-Dawley; Synovial Fluid | 2000 |
A projection from the ventral tegmental area to the periaqueductal gray involved in cardiovascular regulation.
Topics: Anesthetics, Local; Animals; Antimutagenic Agents; Biotin; Blood Pressure; Brain Stem; Cardiovascular System; Cobalt; Dextrans; Glutamic Acid; Lidocaine; Male; Medial Forebrain Bundle; Microinjections; Nerve Block; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2000 |
The anterior pretectal nucleus participates as a relay station in the glutamate-, but not morphine-induced antinociception from the dorsal raphe nucleus in rats.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Animals; Basal Ganglia; Glutamic Acid; Lidocaine; Male; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Neural Pathways; Pain; Pain Measurement; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1 | 2000 |
[Rheologic infusion therapy, neurotransmitter administration and lidocaine injection in tinnitus. A staged therapeutic concept].
Topics: Adolescent; Adult; Aged; Cochlea; Dextrans; Drug Therapy, Combination; Female; Follow-Up Studies; Glutamic Acid; Hair Cells, Auditory; Hemorheology; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Procaine; Tinnitus | 2001 |
Temporomandibular-evoked jaw muscle reflex: role of brain stem NMDA and non-NMDA receptors.
Topics: Anesthetics, Local; Animals; Coloring Agents; Electromyography; Evans Blue; Excitatory Amino Acid Antagonists; Glutamic Acid; Lidocaine; Male; Masticatory Muscles; Membrane Potentials; Muscle Contraction; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Trigeminal Caudal Nucleus | 2001 |
Physiological characteristics of the projection pathway from the medial preoptic to the nucleus raphe magnus of the rat and its modulation by the periaqueductal gray.
Topics: Anesthetics, Local; Animals; Electric Stimulation; Glutamic Acid; Lidocaine; Male; Neural Pathways; Neurons; Pain; Periaqueductal Gray; Preoptic Area; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2001 |
Intracellular QX-314 causes depression of membrane potential oscillations in lamprey spinal neurons during fictive locomotion.
Topics: Action Potentials; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; Lidocaine; Locomotion; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Sodium; Spinal Cord | 2002 |
Dorsal periaqueductal gray matter inhibits passive coping strategy elicited by forced swimming stress in rats.
Topics: Adaptation, Psychological; Anesthetics, Local; Animals; Glutamic Acid; Immobilization; Injections, Intraventricular; Lidocaine; Male; Motor Activity; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Statistics, Nonparametric; Stress, Physiological; Swimming | 2002 |
Independent neuronal oscillators of the rat globus pallidus.
Topics: Action Potentials; Anesthetics, Local; Animals; Bicuculline; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Lidocaine; Methoxyhydroxyphenylglycol; Neurons; Organ Culture Techniques; Periodicity; Rats; Rats, Wistar | 2003 |
A comparison of the neurotoxic effects on the spinal cord of tetracaine, lidocaine, bupivacaine, and ropivacaine administered intrathecally in rabbits.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Glutamic Acid; Injections, Spinal; Lidocaine; Microdialysis; Movement; Rabbits; Ropivacaine; Sensation; Spinal Cord; Tetracaine | 2003 |
Effects of local and intravenous anesthetics on the activity of glutamate transporter type 2.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Animals; Brain Ischemia; Bupivacaine; Cell Membrane; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Ketamine; Lidocaine; Neuroprotective Agents; Oocytes; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Thiopental; Xenopus laevis | 2003 |
Serotonergic facilitation of synaptic activity in the developing rat prefrontal cortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamines; Animals; Bicuculline; Fluorobenzenes; GABA-A Receptor Antagonists; Glutamic Acid; Indoles; Lidocaine; Male; Patch-Clamp Techniques; Phenols; Pindolol; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Sodium Channel Blockers; Sulfonamides; Synapses; Tetrodotoxin; Time Factors | 2004 |
Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel.
Topics: Amino Acid Substitution; Animals; Binding Sites; Electrophysiology; Glutamic Acid; Lidocaine; Lysine; Mutagenesis, Site-Directed; Oocytes; Sodium Channel Blockers; Sodium Channels; Xenopus laevis | 2004 |
Synaptic depolarizing GABA Response in adults is excitatory and proconvulsive when GABAB receptors are blocked.
Topics: 4-Aminopyridine; Anesthetics, Local; Animals; Drug Interactions; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Lidocaine; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Potassium Channel Blockers; Propanolamines; Pyridazines; Receptors, GABA-A; Synaptic Transmission | 2005 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DCC Receptor; Dipeptides; Endopeptidases; Excitatory Postsynaptic Potentials; Genes, DCC; Glutamic Acid; Indoles; Lidocaine; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurites; Neuroblastoma; Neurons; Piperazines; Presenilin-1; Protein Processing, Post-Translational; Pyrroles; Quinoxalines; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Second Messenger Systems; Synaptic Transmission; Transfection; Tumor Suppressor Proteins | 2005 |
Optically recorded response of the superficial dorsal horn: dissociation from neuronal activity, sensitivity to formalin-evoked skin nociceptor activation.
Topics: 4-Aminopyridine; Anesthetics; Animals; Animals, Newborn; Calcium; Diagnostic Imaging; Drug Interactions; Electric Stimulation; Evoked Potentials; Fluoroacetates; Formaldehyde; Functional Laterality; Glutamic Acid; In Vitro Techniques; Lidocaine; Posterior Horn Cells; Potassium; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Reaction Time; Skin; Spinal Cord; Time Factors | 2005 |
Involvement of the periaqueductal gray in the hypotensive response evoked by L-glutamate microinjection in the lateral hypothalamus of unanesthetized rats.
Topics: Animals; Anti-Arrhythmia Agents; Cobalt; Glutamic Acid; Hypotension; Hypothalamus; Injections, Intraventricular; Lidocaine; Male; Microinjections; Neural Pathways; Neurons; Periaqueductal Gray; Rats; Rats, Wistar | 2005 |
Differential modulation of thalamic neurons by optokinetic nuclei in the pigeon.
Topics: Acetylcholine; Action Potentials; Anesthetics, Local; Animals; Brain Mapping; Columbidae; Electric Stimulation; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Lidocaine; Neural Inhibition; Neurons; Photic Stimulation; Piperazines; Thalamus; Visual Pathways | 2006 |
NMDA receptors in layer 4 spiny stellate cells of the mouse barrel cortex contain the NR2C subunit.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Genes, Reporter; Glutamic Acid; Lac Operon; Lidocaine; Magnesium; Membrane Potentials; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Promoter Regions, Genetic; Protein Subunits; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Somatosensory Cortex; Synapses; Synaptic Transmission; Tetrodotoxin | 2006 |
Role of the parvicellular reticular formation in facilitating the jaw-opening reflex in rats by stimulation of the red nucleus.
Topics: Anesthetics, Local; Animals; Electric Stimulation; Electromyography; Functional Laterality; Glutamic Acid; Jaw; Lidocaine; Male; Masticatory Muscles; Medulla Oblongata; Muscle Contraction; Neural Pathways; Rats; Rats, Sprague-Dawley; Red Nucleus; Reflex; Reticular Formation; Synaptic Transmission | 2006 |
Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis.
Topics: Airway Obstruction; Asthma; Bronchi; Bronchial Hyperreactivity; Cell Membrane; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hyperventilation; Lidocaine; Male; Membrane Potentials; Models, Biological; Neurotransmitter Agents; Phenytoin; Respiration Disorders; Sodium Channels | 2006 |
Effects of hypoxia/reperfusion injury on drug disposition in the rat isolated perfused liver.
Topics: Adrenergic beta-Antagonists; Animals; Aspartate Aminotransferases; Carbon Dioxide; Carbon Radioisotopes; Female; Glutamic Acid; Hypoxia; In Vitro Techniques; L-Lactate Dehydrogenase; Lidocaine; Liver; Perfusion; Propranolol; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2007 |
Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels.
Topics: Anesthetics, Local; Arginine; Aspartic Acid; Binding Sites; Cell Line; Cell Membrane Permeability; Glutamic Acid; Humans; Ion Channel Gating; Kinetics; Lidocaine; Lysine; Membrane Potentials; Models, Molecular; Molecular Structure; Muscle Proteins; Mutagenesis, Site-Directed; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenylalanine; Protein Conformation; Sodium Channel Blockers; Sodium Channels; Static Electricity; Transfection | 2007 |
Paraventricular nucleus is involved in the central pathway of cardiac sympathetic afferent reflex in rats.
Topics: Afferent Pathways; Anesthetics, Local; Animals; Blood Pressure; Bradykinin; Capsaicin; Central Nervous System; Excitatory Amino Acid Agonists; Glutamic Acid; Heart; Kainic Acid; Lidocaine; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System | 2008 |
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine | 2008 |
Prefrontal cortex and basolateral amygdala modulation of dopamine-mediated locomotion in the nucleus accumbens core.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Amygdala; Anesthetics, Local; Animals; Dopamine; Dopamine Agonists; Glutamic Acid; Hyperkinesis; Lidocaine; Locomotion; Male; Neural Pathways; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission | 2008 |
Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Behavior, Animal; Benzylamines; Biotin; Chromatography, High Pressure Liquid; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Inhibition, Psychological; Lidocaine; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Psychomotor Performance; Quinoxalines; Racemases and Epimerases; Rotarod Performance Test; Space Perception | 2009 |
[Protective effect of lidocaine on glutamic acid induced neuronal injury in rat].
Topics: Animals; Cells, Cultured; Drug Antagonism; Glutamic Acid; Lidocaine; Neurons; Rats; Rats, Sprague-Dawley | 2008 |
TRPA1 activation by lidocaine in nerve terminals results in glutamate release increase.
Topics: Anesthetics, Local; Animals; Ankyrins; Calcium Channels; Glutamic Acid; Lidocaine; Neurons; Patch-Clamp Techniques; Procaine; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Synaptic Transmission; TRPA1 Cation Channel; TRPC Cation Channels | 2009 |
Comparison of the effects of intrathecal administration of levobupivacaine and lidocaine on the prostaglandin E2 and glutamate increases in cerebrospinal fluid: a microdialysis study in freely moving rats.
Topics: Anesthetics, Local; Animals; Bupivacaine; Dinoprostone; Dose-Response Relationship, Drug; Drug Administration Schedule; Glutamic Acid; Injections, Spinal; Levobupivacaine; Lidocaine; Male; Microdialysis; Rats; Rats, Wistar | 2009 |
The combined neuroprotective effects of lidocaine and dexmedetomidine after transient forebrain ischemia in rats.
Topics: Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain Chemistry; Cerebrovascular Circulation; Dexmedetomidine; Drug Combinations; Glutamic Acid; Heart Rate; Hippocampus; Hypnotics and Sedatives; Ischemic Attack, Transient; Lidocaine; Male; Microdialysis; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Prosencephalon; Rats; Rats, Sprague-Dawley | 2009 |
Glycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patterns.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Lidocaine; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Time Factors; Tubulin; Valine | 2009 |
Effects of local tramadol administration on peripheral glutamate-induced nociceptive behaviour in mice.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Female; Foot; Glutamic Acid; Hot Temperature; Immersion; Lidocaine; Mice; Pain; Pain Measurement; Tramadol | 2010 |
Use-dependent AMPA receptor block reveals segregation of spontaneous and evoked glutamatergic neurotransmission.
Topics: Anesthetics, Local; Animals; Animals, Newborn; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Hippocampus; Lidocaine; Male; Mice; Mice, Knockout; Neurons; Patch-Clamp Techniques; Polyamines; Receptors, AMPA; Tetrodotoxin; Valine | 2011 |
Local anesthetics inhibit glutamate release from rat cerebral cortex synaptosomes.
Topics: Anesthetics, Local; Animals; Bupivacaine; Calcium; Calcium Channel Blockers; Cerebral Cortex; Exocytosis; Glutamic Acid; Lidocaine; Male; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Synaptosomes | 2013 |
Glutamate dysregulation in the trigeminal ganglion: a novel mechanism for peripheral sensitization of the craniofacial region.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthetics, Local; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Lidocaine; Male; Mice; Muscle, Skeletal; Neural Conduction; Neurons; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Time Factors; Trigeminal Ganglion | 2014 |
Galanin-Mediated Behavioural Hyperalgesia from the Dorsomedial Nucleus of the Hypothalamus Involves Two Independent Descending Pronociceptive Pathways.
Topics: Animals; Arthritis; Behavior, Animal; Disease Models, Animal; Electrophysiology; Galanin; Glutamic Acid; Hyperalgesia; Hypothalamus; Lidocaine; Male; Mediodorsal Thalamic Nucleus; Neurons; Nociception; Ondansetron; Pain; Pressure; Protein Precursors; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Serotonin; Spinal Cord | 2015 |
Intravenous administration of lidocaine directly acts on spinal dorsal horn and produces analgesic effect: An in vivo patch-clamp analysis.
Topics: Administration, Intravenous; Analgesics; Animals; Excitatory Postsynaptic Potentials; Glutamic Acid; Lidocaine; Male; Membrane Potentials; Pain Measurement; Patch-Clamp Techniques; Posterior Horn Cells; Rats, Wistar; Synaptic Transmission | 2016 |
Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats.
Topics: Animals; Benzhydryl Compounds; Benzoxazoles; Corpus Striatum; Glutamic Acid; Hyperalgesia; Lidocaine; Male; Medulla Oblongata; Microinjections; Neuralgia; Neurons; Neuroprotective Agents; Pain; Rats; Receptors, Metabotropic Glutamate; Reticular Formation; Sciatic Nerve; Subthalamic Nucleus | 2018 |
Dexmedetomidine ameliorates lidocaine-induced spinal neurotoxicity via inhibiting glutamate release and the PKC pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Spinal; Lidocaine; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord | 2018 |
Lidocaine protects neurons of the spinal cord in an excitotoxicity model.
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Kainic Acid; Lidocaine; Male; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2019 |
Etomidate-induced myoclonus correlates with the dysfunction of astrocytes and glutamate transporters in the neocortex of Sprague-Dawley rats.
Topics: Amino Acid Transport System X-AG; Animals; Anticonvulsants; Astrocytes; Etomidate; Glutamic Acid; Hypnotics and Sedatives; Lidocaine; Male; Myoclonus; Neocortex; Propofol; Rats; Rats, Sprague-Dawley | 2022 |
Etomidate-Induced Myoclonus in Sprague-Dawley Rats Involves Neocortical Glutamate Accumulation and N -Methyl- d -Aspartate Receptor Activity.
Topics: Anesthetics, Intravenous; Animals; Etomidate; Glutamic Acid; Lidocaine; Male; Myoclonus; Neocortex; Propofol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2023 |