lidocaine and gabapentin

lidocaine has been researched along with gabapentin in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.43)18.2507
2000's27 (38.57)29.6817
2010's34 (48.57)24.3611
2020's8 (11.43)2.80

Authors

AuthorsStudies
Jolivette, LJ; Ward, KW1
Jolivette, LJ; Nagilla, R; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abdi, S; Chung, JM; Lee, DH1
Maneksha, FR; Mirza, H; Poppers, PJ1
Brecker, C; Eisenberg, E1
Dworkin, RH; Schmader, KE1
Drass, M; Nalamachu, S; Patel, N; White, WT1
Nicholson, BD1
Simpson, MA1
Bertelli, JA; Calixto, JB; Campos, MM; Ferreira, J; Rodrigues-Filho, R; Santos, AR1
Ali, H; Boutwell, C; Dubinsky, RM; El-Chami, Z; Kabbani, H1
Baron, R; Wasner, G1
Vandermeulen, E1
Maurya, PK; Mishra, VN; Pradhan, S; Yadav, R1
Forde, G1
Cohen, AS1
Dakin, H; Liedgens, H; Nautrup, BP; Nuijten, M1
Gore, M; Sadosky, A; Stacey, B; Tai, KS1
Cohen, AS; Goadsby, PJ1
Rudick, CN; Schaeffer, AJ; Thumbikat, P1
Goicochea, MT; Leston, JA; Romero, C1
Dakin, H; Gabriel, A; Hertel, N; Liedgens, H; Mitchell, S; Nautrup, BP; Nuijten, M1
Forde, G; Stanos, S1
Yamamoto, T1
Dworkin, RH; O'Connor, AB1
Chatterjee, N; Koshy, T; Misra, S; Suneel, PR; Unnikrishnan, KP1
Ben-Joseph, RH; Birnbaum, HG; Ivanova, JI; Kantor, E; Kirson, NY; Puenpatom, RA; Summers, KH; Wei, R1
Bala, MM; Kessels, AG; Kleijnen, J; Westwood, M; Wolff, RF1
Armstrong, EP; Malone, DC; McCarberg, B; Panarites, CJ; Pham, SV1
Gessler, EM; Touchette, D1
Argoff, CE1
Berner, R; Creutzfeldt, R; Hufnagel, M; Jakob, A; Staszewski, O; Winterpacht, A1
Albert, DA; Jones, JD; Rigby, WF; Thadani, V1
Hatashima, S; Kawasaki, M; Matsuda, T1
Déciga-Campos, M; García-Hernández, L; González-Trujano, ME; López-Muñoz, FJ; Navarrete-Vázquez, G1
Eliav, E; Haribabu, PK; Heir, GM1
Álvarez, M; Pareja, JA1
Holland, MG; Marraffa, JM; Ryzewski, M; Sullivan, RW1
Bonanno, L; Cammaroto, G; Ciodaro, F; Galletti, B; Galletti, F; Mannella, VK1
Johnson, RW; Rice, AS1
Esin, OR; Esin, RG; Sitnova, MA1
Angert, M; Chernov, AV; Dolkas, J; Eddinger, KA; Ko, JS; Shubayev, VI; Strongin, AY; Yaksh, TL1
Gibbs, LM; Lindsay, TJ; Snyder, MJ1
Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S1
Attal, N; Baron, R; Bennett, DL; Bouhassira, D; Colloca, L; Dickenson, AH; Dworkin, RH; Eccleston, C; Finnerup, NB; Freeman, R; Kalso, E; Ludman, T; Raja, SN; Truini, A; Yarnitsky, D1
Kalva, S; Palumbo, A; Singh, K; Toomay, S1
Berenato, F; Chan, YH; Grossman, SK; Korbutov, J; Lavery, MJ; Lee, HG; Valdes-Rodriguez, R; Yosipovitch, G1
Katz, P; Liedgens, H; Pegoraro, V1
Grant, MC; Wick, EC; Wu, CL1
Baraldi, C; Cainazzo, MM; Guerzoni, S; Pellesi, L; Pini, LA1
Hannon, M; Quail, J; Spence, D1
Bhaskar, A; Humble, SR; Jayaweera, A; Varela, N1
Smith, KE; Wampole, CR1
Avitsian, R; Krishnaney, A; Kurz, A; Machado, A; Machado, S; Maheshwari, K; Makarova, N; Manlapaz, M; Rajan, S; Raza, S; Rosenquist, R; Sessler, DI; Tanios, M; Traul, D1
Bao, HG; Han, Q; Liao, YM; Lu, HF; Si, YN; Xie, P; Zhang, QX; Zhao, Y; Zuo, XH1
Li, H; Li, P; Li, S; Wang, R1
Senet, P1
Huang, Y; Li, J; Lin, J1
Billings, FT; Clifton, JC; Freundlich, RE; Hernandez, A; Jelly, CA; Schaffer, AJ; Shotwell, ME1
Guo, K; Huang, J; Huang, Y; Jin, L; Liang, Y; Miao, P; Wang, C; Wang, H; Xu, L; Yu, Y1
Liu, C; Song, L; Tang, J; Zeng, A; Zhang, Y1

Reviews

23 review(s) available for lidocaine and gabapentin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Treatment and prevention of postherpetic neuralgia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Apr-01, Volume: 36, Issue:7

    Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lidocaine; Neuralgia; Randomized Controlled Trials as Topic

2003
Diagnosis and management of neuropathic pain: a balanced approach to treatment.
    Journal of the American Academy of Nurse Practitioners, 2003, Volume: 15, Issue:12 Suppl

    Topics: Acetates; Amines; Antidepressive Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lidocaine; Narcotics; Neuralgia; Nurse Practitioners; Pain Measurement; Prevalence

2003
Practice parameter: treatment of postherpetic neuralgia: an evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology.
    Neurology, 2004, Sep-28, Volume: 63, Issue:6

    Topics: Acupuncture Analgesia; Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Anticonvulsants; Antidepressive Agents, Tricyclic; Antiviral Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Evaluation; Evidence-Based Medicine; Excitatory Amino Acid Antagonists; Forecasting; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Iontophoresis; Lidocaine; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate

2004
Systemic analgesia and co-analgesia.
    Acta anaesthesiologica Belgica, 2006, Volume: 57, Issue:2

    Topics: Amines; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Dexmedetomidine; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Lidocaine; Narcotic Antagonists; Pain, Postoperative

2006
Adjuvant analgesics for the treatment of neuropathic pain: evaluating efficacy and safety profiles.
    The Journal of family practice, 2007, Volume: 56, Issue:2 Suppl Pa

    Topics: Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents; Arthritis; Chemotherapy, Adjuvant; Chronic Disease; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Low Back Pain; Pain; Pain Measurement; Pain, Postoperative; Practice Guidelines as Topic; Pregabalin; Wounds and Injuries

2007
[Pathophysiology and treatment of trigeminal autonomic cephalalgias].
    Schmerz (Berlin, Germany), 2008, Volume: 22 Suppl 1

    Topics: Administration, Oral; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Methysergide; Nociceptors; Oxygen Inhalation Therapy; Paroxysmal Hemicrania; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias; Trigeminal Nerve; Vasoconstrictor Agents; Vasodilator Agents; Verapamil

2008
Practical management strategies for the chronic pain patient.
    The Journal of family practice, 2007, Volume: 56, Issue:8 Suppl Ho

    Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chronic Disease; Clinical Protocols; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged; Pain; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Substance-Related Disorders; Thiophenes; Treatment Outcome

2007
[Mechanisms of the development of neuropathic pain and its treatment].
    Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association, 2008, Volume: 77, Issue:3

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Leprosy; Lidocaine; Neuralgia; Posterior Horn Cells; Pregabalin; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers

2008
Treatment of neuropathic pain: an overview of recent guidelines.
    The American journal of medicine, 2009, Volume: 122, Issue:10 Suppl

    Topics: Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Antidepressive Agents; Canada; Cyclohexanecarboxylic Acids; Europe; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; International Cooperation; Lidocaine; Neuralgia; Practice Guidelines as Topic; Pregabalin; Selective Serotonin Reuptake Inhibitors; Societies, Medical; Tramadol

2009
5% lidocaine-medicated plaster vs other relevant interventions and placebo for post-herpetic neuralgia (PHN): a systematic review.
    Acta neurologica Scandinavica, 2011, Volume: 123, Issue:5

    Topics: Administration, Cutaneous; Amines; Analgesics; Anesthetics, Local; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia, Postherpetic; Treatment Outcome

2011
Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia.
    Current medical research and opinion, 2011, Volume: 27, Issue:5

    Topics: Administration, Topical; Amines; Anesthetics, Local; Antidepressive Agents, Tricyclic; Capsaicin; Clinical Trials as Topic; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Markov Chains; Neuralgia, Postherpetic; Pregabalin; Quality of Life; Sensory System Agents; Thiophenes; Transdermal Patch

2011
Review of current guidelines on the care of postherpetic neuralgia.
    Postgraduate medicine, 2011, Volume: 123, Issue:5

    Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Capsaicin; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia, Postherpetic; Practice Guidelines as Topic; Pregabalin; Primary Health Care; Tramadol; Transdermal Patch

2011
The usual treatment of trigeminal autonomic cephalalgias.
    Headache, 2013, Volume: 53, Issue:9

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Sumatriptan; SUNCT Syndrome; Topiramate; Treatment Outcome; Trigeminal Autonomic Cephalalgias

2013
Clinical practice. Postherpetic neuralgia.
    The New England journal of medicine, 2014, Oct-16, Volume: 371, Issue:16

    Topics: Administration, Topical; Aged; Amines; Analgesics, Opioid; Anesthetics, Local; Antipyretics; Capsaicin; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Herpes Zoster Vaccine; Humans; Lidocaine; Neuralgia, Postherpetic; Pregabalin

2014
Treating Painful Diabetic Peripheral Neuropathy: An Update.
    American family physician, 2016, Aug-01, Volume: 94, Issue:3

    Topics: Administration, Topical; Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anesthetics, Local; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Isosorbide Dinitrate; Lidocaine; Phenols; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin and Noradrenaline Reuptake Inhibitors; Tapentadol; Tramadol; Transcutaneous Electric Nerve Stimulation; Vasodilator Agents; Venlafaxine Hydrochloride

2016
Analgesia in the surgical intensive care unit.
    Postgraduate medical journal, 2017, Volume: 93, Issue:1095

    Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities

2017
Neuropathic pain.
    Nature reviews. Disease primers, 2017, Feb-16, Volume: 3

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Narcotics; Neoplasms; Neuralgia; Nociceptive Pain; Pain Management; Pregabalin; Quality of Life; Tramadol; Transcutaneous Electric Nerve Stimulation; Voltage-Gated Sodium Channel Blockers

2017
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
    JAMA surgery, 2017, 07-01, Volume: 152, Issue:7

    Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; N-Methylaspartate; Pain, Postoperative; Postoperative Care; Pregabalin; Tramadol

2017
Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal.
    The journal of headache and pain, 2017, Volume: 18, Issue:1

    Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Neuralgia; Paroxysmal Hemicrania; Reproducibility of Results; SUNCT Syndrome; Surveys and Questionnaires; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias

2017
Chronic postsurgical pain and cancer: the catch of surviving the unsurvivable.
    Current opinion in supportive and palliative care, 2018, Volume: 12, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Chronic Pain; Drug Therapy, Combination; Gabapentin; Genetic Predisposition to Disease; Humans; Ketamine; Lidocaine; Pain, Postoperative; Palliative Care; Perioperative Care; Risk Factors; Sex Factors; Socioeconomic Factors

2018
Different interventions for preventing postoperative catheter-related bladder discomfort: a systematic review and meta-analysis.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:6

    Topics: Chlorpheniramine; Dexmedetomidine; Gabapentin; Haloperidol; Humans; Ketamine; Lidocaine; Meperidine; Nefopam; Pain, Postoperative; Pregabalin; Tolterodine Tartrate; Tramadol; Urinary Bladder; Urinary Catheters

2022
Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives.
    Current pain and headache reports, 2023, Volume: 27, Issue:9

    Topics: Aged; Analgesics; Antidepressive Agents, Tricyclic; Gabapentin; Humans; Lidocaine; Neuralgia, Postherpetic; Pregabalin

2023

Trials

7 trial(s) available for lidocaine and gabapentin

ArticleYear
Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain.
    Pain medicine (Malden, Mass.), 2003, Volume: 4, Issue:4

    Topics: Acetates; Activities of Daily Living; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Chronic Disease; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Low Back Pain; Male; Middle Aged; Neuralgia; Pain; Pain Measurement; Pilot Projects; Quality of Life; Treatment Outcome

2003
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing.
    Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:7

    Topics: Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Autonomic Nervous System Diseases; Cohort Studies; Conjunctiva; Cyclohexanecarboxylic Acids; Fructose; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothalamus, Posterior; Indomethacin; Lamotrigine; Lidocaine; Magnetic Resonance Imaging; Oxygen; Pain Measurement; Phenotype; Prospective Studies; SUNCT Syndrome; Tears; Topiramate; Triazines

2007
Gabapentin premedication decreases the hemodynamic response to skull pin insertion in patients undergoing craniotomy.
    Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Amines; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Local; Blood Pressure; Bone Nails; Brain Neoplasms; Craniotomy; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Humans; Intraoperative Period; Lidocaine; Male; Methyl Ethers; Middle Aged; Preanesthetic Medication; Prospective Studies; Respiratory Function Tests; Sevoflurane; Skull; Young Adult

2011
Oral gabapentin and intradermal injection of lidocaine: is there any role in the treatment of moderate/severe tinnitus?
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:10

    Topics: Administration, Oral; Adult; Amines; Anesthetics, Local; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intradermal; Lidocaine; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Tinnitus; Treatment Outcome; Young Adult

2015
Perioperative Gabapentin Improves Patient-Centered Outcomes After Inguinal Hernia Repair.
    Military medicine, 2017, Volume: 182, Issue:11

    Topics: Adjuvants, Anesthesia; Adult; Amines; Androstanols; Anesthetics, Local; Antiemetics; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hernia, Inguinal; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; Middle Aged; Neuromuscular Depolarizing Agents; Ondansetron; Placebos; Plastic Surgery Procedures; Propofol; Quality of Life; Rocuronium; Succinylcholine; Treatment Outcome

2017
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
    Anesthesiology, 2020, Volume: 132, Issue:5

    Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; Humans; Ketamine; Lidocaine; Male; Middle Aged; Pain Management; Pain, Postoperative; Spinal Diseases

2020
Evaluation of the Effect of New Multimodal Analgesia Regimen for Cardiac Surgery: A Prospective, Randomized Controlled, Single-Center Clinical Study.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Acetaminophen; Analgesia; Cardiac Surgical Procedures; Chronic Pain; Dexmedetomidine; Gabapentin; Humans; Ketamine; Lidocaine; Prospective Studies; Sufentanil

2023

Other Studies

40 other study(ies) available for lidocaine and gabapentin

ArticleYear
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
The anti-allodynic effects of amitriptyline, gabapentin, and lidocaine in a rat model of neuropathic pain.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:6

    Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Infusions, Intravenous; Infusions, Parenteral; Lidocaine; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley

1998
Complex regional pain syndrome (CRPS) with resistance to local anesthetic block: a case report.
    Journal of clinical anesthesia, 2000, Volume: 12, Issue:1

    Topics: Acetates; Amines; Amitriptyline; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Cyclohexanecarboxylic Acids; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocodone; Lidocaine; Nerve Block; Physical Therapy Modalities; Posterior Horn Cells; Receptors, N-Methyl-D-Aspartate; Reflex Sympathetic Dystrophy; Sympathetic Nervous System

2000
Lumbar spinal cord stimulation for cervical-originated central pain: a case report.
    Pain, 2002, Volume: 100, Issue:3

    Topics: Acetates; Amines; Antidepressive Agents, Tricyclic; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Electric Stimulation Therapy; Electrodes, Implanted; Female; Foramen Magnum; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Lidocaine; Lumbosacral Region; Meningeal Neoplasms; Meningioma; Middle Aged; Pain; Pain Management; Pain, Intractable; Pain, Postoperative

2002
Conquering peripheral neuropathic pain.
    Nursing, 2004, Volume: 34, Issue:6

    Topics: Acetates; Amines; Analgesics; Anesthetics, Local; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia

2004
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain.
    Brain research, 2004, Aug-27, Volume: 1018, Issue:2

    Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Brachial Plexus; Brachial Plexus Neuropathies; Celecoxib; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ketamine; Lidocaine; Male; Morphine; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Pyrazoles; Radiculopathy; Rats; Rats, Wistar; Sulfonamides

2004
Prevention and treatment of postherpetic neuralgia.
    Lancet (London, England), 2006, Jan-21, Volume: 367, Issue:9506

    Topics: Adult; Amines; Anesthetics, Local; Antiviral Agents; Calcium Channel Blockers; Child, Preschool; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Lidocaine; Methylprednisolone; Neuralgia, Postherpetic

2006
Focal myelomalacia and syrinx formation after accidental intramedullary lidocaine injection during lumbar anesthesia: a report of 3 cases.
    Journal of the neurological sciences, 2006, Dec-21, Volume: 251, Issue:1-2

    Topics: Adult; Amines; Anesthesia, Spinal; Anesthetics, Local; Carbamazepine; Cesarean Section; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Lidocaine; Lumbosacral Region; Magnetic Resonance Imaging; Spinal Cord Diseases

2006
Cost-effectiveness of a lidocaine 5% medicated plaster relative to gabapentin for postherpetic neuralgia in the United Kingdom.
    Clinical therapeutics, 2007, Volume: 29, Issue:7

    Topics: Administration, Cutaneous; Aged; Amines; Analgesics; Anesthetics, Local; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Markov Chains; Models, Econometric; Neuralgia, Postherpetic; Quality-Adjusted Life Years

2007
A retrospective evaluation of the use of gabapentin and pregabalin in patients with postherpetic neuralgia in usual-care settings.
    Clinical therapeutics, 2007, Volume: 29, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Databases as Topic; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Practice Patterns, Physicians'; Pregabalin; Retrospective Studies; Tramadol; Treatment Outcome; United States

2007
Experimental autoimmune prostatitis induces chronic pelvic pain.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:4

    Topics: Amines; Analgesics; Anesthetics, Local; Animals; Autoimmune Diseases; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lidocaine; Male; Mice; Mice, Inbred NOD; Nerve Fibers; Pain Measurement; Pelvic Pain; Prostate; Prostatitis; Rats; Rats, Inbred BB; Syndrome; Time Factors; Tissue Extracts

2008
Occipital neuralgia with cervical myelitis.
    Cephalalgia : an international journal of headache, 2008, Volume: 28, Issue:5

    Topics: Amines; Analgesics; Anesthetics, Local; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Facial Neuralgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Middle Aged; Myelitis; Occipital Lobe; Rare Diseases; Treatment Outcome

2008
Cost-effectiveness analysis of a lidocaine 5% medicated plaster compared with gabapentin and pregabalin for treating postherpetic neuralgia: a german perspective.
    Clinical drug investigation, 2008, Volume: 28, Issue:9

    Topics: Administration, Cutaneous; Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Delphi Technique; Drug Costs; Endpoint Determination; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Germany; Lidocaine; Markov Chains; Models, Economic; Models, Statistical; National Health Programs; Neuralgia, Postherpetic; Pain Measurement; Pregabalin; Quality-Adjusted Life Years

2008
Comparing healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% versus gabapentin or pregabalin.
    Journal of medical economics, 2010, Volume: 13, Issue:3

    Topics: Amines; Analgesics; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Health Services; Humans; Insurance Claim Review; Lidocaine; Male; Medicaid; Middle Aged; Neuralgia, Postherpetic; Pregabalin; Retrospective Studies; Transdermal Patch; United States

2010
Painful traumatic neuroma of the tongue treated with serial alcohol injections.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2011, Volume: 145, Issue:4

    Topics: Aged; Amines; Analgesics; Anesthetics, Local; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intralesional; Lidocaine; Neoplasm Recurrence, Local; Neuroma; Pain; Tongue Neoplasms

2011
Primary erythromelalgia in a 12-year-old boy: positive response to sodium channel blockers despite negative SCN9A mutations.
    Klinische Padiatrie, 2012, Volume: 224, Issue:5

    Topics: Administration, Oral; Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Diagnosis, Differential; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythromelalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Lidocaine; Male; Mexiletine; NAV1.7 Voltage-Gated Sodium Channel; Nitroprusside; Sodium Channel Blockers; Treatment Outcome; Vasodilator Agents

2012
Unusual case of a swollen painful toe in a young man.
    Arthritis care & research, 2012, Volume: 64, Issue:2

    Topics: Acne Vulgaris; Adult; Amines; Analgesics, Opioid; Anti-Bacterial Agents; Arthritis; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Doxycycline; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Gonorrhea; Hallux; Humans; Lidocaine; Lyme Disease; Magnetic Resonance Imaging; Male; Neuritis; Syphilis; Tramadol; Treatment Outcome

2012
Non-surgical therapy for bilateral glossopharyngeal neuralgia caused by Eagle's syndrome, diagnosed by three-dimensional computed tomography: a case report.
    Journal of anesthesia, 2012, Volume: 26, Issue:6

    Topics: Aged; Amines; Analgesics; Anesthetics, Local; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglionic Blockers; Glossopharyngeal Nerve Diseases; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lidocaine; Male; Ossification, Heterotopic; Pain; Pain Measurement; Stellate Ganglion; Temporal Bone; Tomography, X-Ray Computed

2012
Antihyperalgesic activity of a novel synthesized analogue of lidocaine in diabetic rats.
    The Journal of pharmacy and pharmacology, 2013, Volume: 65, Issue:5

    Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Diabetes Complications; Diabetes Mellitus, Experimental; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Lidocaine; Molecular Structure; Nociceptive Pain; Pain; Pain Measurement; Rats; Reference Values

2013
Topical medications for the effective management of neuropathic orofacial pain.
    Journal of the American Dental Association (1939), 2013, Volume: 144, Issue:6

    Topics: Administration, Topical; Amines; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperesthesia; Iatrogenic Disease; Ketoprofen; Lidocaine; Maxillary Nerve; Middle Aged; Neuralgia; Radicular Cyst

2013
Compounded ointment results in severe toxicity in a pediatric patient.
    Pediatric emergency care, 2013, Volume: 29, Issue:11

    Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined Modality Therapy; Consciousness Disorders; Cyclohexanecarboxylic Acids; Diaper Rash; Drug Combinations; Drug Compounding; Drug Overdose; Emergencies; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Ketamine; Lidocaine; Male; Mefenamic Acid; Ointments; Reflex, Abnormal; Respiration Disorders; Skin Absorption

2013
[Shingles symptoms are gone but not the pain].
    MMW Fortschritte der Medizin, 2015, Jul-23, Volume: 157, Issue:13

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Amines; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclohexanecarboxylic Acids; Dipyrone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Guideline Adherence; Humans; Ibuprofen; Lidocaine; Neuralgia, Postherpetic; Phenols; Pregabalin; Tapentadol; Treatment Failure

2015
[The principles of pharmacotherapy of poststroke shoulder pain].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:5

    Topics: Amines; Amitriptyline; Anti-Inflammatory Agents; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Pregabalin; Shoulder Pain; Stroke

2015
Spinal activity of interleukin 6 mediates myelin basic protein-induced allodynia.
    Brain, behavior, and immunity, 2016, Volume: 56

    Topics: Amines; Animals; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Genomics; Hyperalgesia; Interleukin-6; Ketorolac; Lidocaine; Myelin Basic Protein; Peptide Fragments; Rats; Rats, Nude; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Voltage-Gated Sodium Channel Blockers

2016
Angiography in Complex Regional Pain Syndrome.
    Journal of vascular and interventional radiology : JVIR, 2017, Volume: 28, Issue:3

    Topics: Amines; Analgesics; Anesthetics, Local; Angiography; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Finger Injuries; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged

2017
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability.
    Journal of the American Academy of Dermatology, 2017, Volume: 76, Issue:4

    Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Lidocaine; Male; Mianserin; Mirtazapine; Pain Measurement; Pruritus; Retrospective Studies

2017
Characteristics, resource utilization and safety profile of patients prescribed with neuropathic pain treatments: a real-world evidence study on general practices in Europe - the role of the lidocaine 5% medicated plaster.
    Current medical research and opinion, 2017, Volume: 33, Issue:8

    Topics: Aged; Aged, 80 and over; Amines; Anesthetics, Local; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Europe; Female; Gabapentin; gamma-Aminobutyric Acid; General Practice; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Pregabalin; Retrospective Studies; Treatment Outcome

2017
Beyond Opioids for Pain Management in Adult Critically Ill Patients.
    Journal of pharmacy practice, 2019, Volume: 32, Issue:3

    Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Adult; Analgesia; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Critical Care; Critical Illness; Gabapentin; Humans; Ketamine; Lidocaine; Pain; Pain Management; Pain Measurement

2019
Thermographic follow-up of postherpetic neuralgia (PHN) subsequent to Ramsay Hunt syndrome with multicranial nerve (V, VII, VIII and IX) involvement: a case report.
    BMC neurology, 2021, Jan-28, Volume: 21, Issue:1

    Topics: Aged; Analgesics; Anesthetics, Local; Follow-Up Studies; Gabapentin; Herpes Zoster Oticus; Humans; Lidocaine; Male; Neuralgia, Postherpetic; Phototherapy; Pulsed Radiofrequency Treatment; Thermography

2021
[Paroxysmal vascular acrosyndromes: Practical approach to diagnosis and management].
    La Revue de medecine interne, 2022, Volume: 43, Issue:10

    Topics: Antibodies, Antinuclear; Aspirin; Calcium Channel Blockers; Erythromelalgia; Gabapentin; Humans; Iloprost; Lidocaine; Mexiletine; Raynaud Disease; Small Fiber Neuropathy; Sodium Channel Blockers

2022
[Efficacy analysis of lidocaine plaster combined with gabapentin in the treatment of herpes zoster neuralgia].
    Zhonghua yi xue za zhi, 2022, Nov-01, Volume: 102, Issue:40

    Topics: Aged; Female; Gabapentin; Herpes Zoster; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Quality of Life; Treatment Outcome

2022
The Association Between Enhanced Recovery After Cardiac Surgery-Guided Analgesics and Postoperative Delirium.
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:5

    Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Dexmedetomidine; Emergence Delirium; Gabapentin; Humans; Ketamine; Lidocaine; Pain, Postoperative

2023