lidocaine and flurbiprofen

lidocaine has been researched along with flurbiprofen in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's0 (0.00)18.2507
2000's10 (32.26)29.6817
2010's16 (51.61)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Caron, G; Ermondi, G1
Jolivette, LJ; Nagilla, R; Ward, KW1
Carrupt, PA; Martel, S; Ottaviani, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dionne, RA1
Verstraete, M1
Nishiyama, T1
Fujii, Y; Itakura, M2
Taylor, LS; Van Eerdenbrugh, B1
He, G; Liu, Z; Lu, H; Ma, H; Wang, J1
Miller, AF; Saiani, A; Tang, C1
Abbas, N; Ahmad, Z; Akhlaq, M; Arshad, MS; Bukhari, NI; Hanif, S; Hussain, A; Hussain, K; Syed, MA1
Bai, WJ; Lan, K; Li, Q; Xu, T; Yang, WB; Zhang, XW1
Glatz, Z; Michalcová, L; Nevídalová, H1
Fu, J; Lu, G; Sun, W; Ye, X; Yu, J1
Kozak, J; Lamprecht, A; Rabiskova, M1

Reviews

2 review(s) available for lidocaine and flurbiprofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Critical evaluation of the usefulness of drugs inhibiting platelet function in the prevention of postoperative deep venous thrombosis and in ischemic cardiopathy].
    Recenti progressi in medicina, 1980, Volume: 68, Issue:4

    Topics: Anticoagulants; Aspirin; Clofibrate; Coronary Disease; Dipyridamole; Fibrinolytic Agents; Flurbiprofen; Humans; Hydroxychloroquine; Lidocaine; Platelet Aggregation; Postoperative Complications; Pulmonary Embolism; Sulfinpyrazone; Thromboembolism; Thrombophlebitis

1980

Trials

6 trial(s) available for lidocaine and flurbiprofen

ArticleYear
Suppression of dental pain by the preoperative administration of flurbiprofen.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Acetaminophen; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Etidocaine; Flurbiprofen; Humans; Lidocaine; Oxycodone; Pain, Postoperative; Premedication; Propionates; Random Allocation; Tooth Extraction

1986
How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen.
    Journal of anesthesia, 2005, Volume: 19, Issue:4

    Topics: Adult; Aged; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Female; Flurbiprofen; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Pain; Preanesthetic Medication; Propofol

2005
Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study.
    Clinical therapeutics, 2008, Volume: 30, Issue:2

    Topics: Adult; Aged; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; Flurbiprofen; Humans; Injections, Intravenous; Japan; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Pain Measurement; Propofol; Prospective Studies; Surgical Procedures, Operative; Treatment Outcome; Young Adult

2008
Efficacy of the lidocaine/flurbiprofen axetil combination for reducing pain during the injection of propofol.
    Minerva anestesiologica, 2011, Volume: 77, Issue:7

    Topics: Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Combinations; Elective Surgical Procedures; Female; Flurbiprofen; Humans; Injections; Lidocaine; Male; Middle Aged; Pain; Propofol; Young Adult

2011
Non-steroidal anti-inflammatory drugs reduce the stress response during sevoflurane anesthesia.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:7

    Topics: Adult; Anesthesia, Inhalation; Anesthetics, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase 2 Inhibitors; Female; Flurbiprofen; Heart Rate; Humans; Infusions, Intravenous; Intraoperative Complications; Isoxazoles; Lidocaine; Male; Methyl Ethers; Middle Aged; Prospective Studies; Pulmonary Alveoli; Sevoflurane; Skin; Sodium Channel Blockers; Young Adult

2012
[Application of flurbiprofen axetil in pain management associated during transrectal ultrasound-guided prostate biopsy].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2017, 08-18, Volume: 49, Issue:4

    Topics: Anesthetics, Local; Biopsy; Flurbiprofen; Humans; Lidocaine; Male; Nerve Block; Pain Management; Prostatic Neoplasms

2017

Other Studies

23 other study(ies) available for lidocaine and flurbiprofen

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Small scale screening to determine the ability of different polymers to inhibit drug crystallization upon rapid solvent evaporation.
    Molecular pharmaceutics, 2010, Aug-02, Volume: 7, Issue:4

    Topics: Acrylates; Benzamides; Chlorpropamide; Chlorzoxazone; Chromatography, High Pressure Liquid; Crystallization; Flurbiprofen; Hypromellose Derivatives; Imidazoles; Lidocaine; Methylcellulose; Phenacetin; Polymers; Polyvinyls; Povidone; Pyrrolidines; Solvents

2010
Peptide hydrogels as mucoadhesives for local drug delivery.
    International journal of pharmaceutics, 2014, Apr-25, Volume: 465, Issue:1-2

    Topics: Adhesiveness; Chemistry, Pharmaceutical; Drug Carriers; Flurbiprofen; Hydrogels; Kinetics; Lidocaine; Membranes, Artificial; Mucous Membrane; Oligopeptides; Solubility; Technology, Pharmaceutical; Viscosity

2014
Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain.
    Acta pharmaceutica (Zagreb, Croatia), 2016, Jun-01, Volume: 66, Issue:2

    Topics: Adhesiveness; Administration, Buccal; Alginates; Anesthetics, Local; Cyclooxygenase Inhibitors; Drug Compounding; Flurbiprofen; Glucuronic Acid; Hexuronic Acids; Humans; Hypromellose Derivatives; Kinetics; Lidocaine; Models, Chemical; Mouth Mucosa; Neural Networks, Computer; Solubility; Tablets; Technology, Pharmaceutical; Toothache

2016
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
    Journal of separation science, 2020, Volume: 43, Issue:22

    Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan

2020
Clinical therapeutic effects of lidocaine combination with flurbiprofen axetil for reducing propofol-induced pain in adults: A protocol for systematic review and meta-analysis.
    Medicine, 2020, Dec-24, Volume: 99, Issue:52

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Drug Therapy, Combination; Flurbiprofen; Humans; Lidocaine; Meta-Analysis as Topic; Pain, Procedural; Propofol; Research Design; Systematic Reviews as Topic; Treatment Outcome

2020
Muscle Tissue as a Surrogate for In Vitro Drug Release Testing of Parenteral Depot Microspheres.
    AAPS PharmSciTech, 2021, Mar-29, Volume: 22, Issue:3

    Topics: Animals; Cellulose; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Excipients; Flurbiprofen; In Vitro Techniques; Infusions, Parenteral; Lidocaine; Microspheres; Muscles; Polylactic Acid-Polyglycolic Acid Copolymer; Risperidone; Swine

2021