lidocaine has been researched along with disopyramide in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 126 (64.62) | 18.7374 |
| 1990's | 40 (20.51) | 18.2507 |
| 2000's | 22 (11.28) | 29.6817 |
| 2010's | 7 (3.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Jolivette, LJ; Nagilla, R; Ward, KW | 1 |
| Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Sen, S; Sinha, N | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Theisen, K | 1 |
| Carson, IW; Lyons, SM; Shanks, RG | 1 |
| Green, AG | 1 |
| Ruffy, R; Zipes, DP | 1 |
| Singh, BN | 1 |
| Shand, DG; Woosley, RL | 1 |
| Forester, D | 1 |
| Federman, J; Vlietstra, RE | 1 |
| Fozzard, HA; Rawling, DA; Sbarbaro, JA | 1 |
| Bax, ND; Martin, MA; Tucker, GT; Ward, JW | 2 |
| Kus, T; Sasyniuk, BI | 2 |
| Pennock, RS | 1 |
| Anderson, JL; Harrison, DC; Meffin, PJ; Winkle, RA | 1 |
| Lagerström, PO; Persson, BA | 1 |
| Goldman, P; Ingelfinger, JA | 1 |
| Ankier, SI; Grant, AM; Marshall, RJ | 1 |
| Mason, JW; Winkle, RA | 1 |
| Farshidi, A; Greenspan, AM; Horowitz, LN; Josephson, ME; Michelson, EL; Spielman, SR | 1 |
| Arnsdorf, MF; Mehlman, DJ | 1 |
| Barrillon, A; Grand, A | 1 |
| Kidner, PH | 1 |
| de Lanerolle, TD; Edmunds, V; Wilcox, AH | 1 |
| Araú, A; Bonhorst, D; Bordalo, A; De Azevedo, JG; Ferreira, M; Ferreira, R; Inês, L; Lacximy, I; Longo, A; Luis Martins, J; Melo, M; Nunes Diogo, A; Ribeiro, C; Sanches, C; Teixeira, J | 1 |
| Arita, M; Kiyosue, T; Sato, T; Wu, B | 1 |
| Barber, MJ; Grant, AO; Starmer, CF; Wendt, DJ | 1 |
| Furukawa, T; Hiraoka, M; Marumo, F; Nitta, J; Sawanobori, T; Sunami, A | 1 |
| Handa, S; Ogawa, S; Okada, Y; Sadanaga, T | 1 |
| Ikeda, N; Kamiya, K | 1 |
| Hanano, M; Iga, T; Okudaira, K; Sawada, Y; Sugiyama, Y; Yamazaki, M | 1 |
| Boachie-Ansah, G; Kane, KA; Pacini, DJ | 1 |
| Campbell, TJ; Pallandi, R; Wyse, KR | 1 |
| Asayama, J; Inoue, D; Inoue, M; Katsume, H; Nakagawa, M; Shirayama, T; Tatsumi, T; Yamahara, Y | 1 |
| Fan, Z; Hiraoka, M; Nitta, J; Sunami, A | 1 |
| Buckett, WR; Kellett, R; Martin, KF | 1 |
| Fukami, M; Hashimoto, T; Itoh, Y; Koike, H; Kumakura, S; Miyake, S; Mizuno, H; Shiga, H; Shimoji, Y; Yorikane, R | 1 |
| Akaike, N; Inomata, N; Ishihara, T | 1 |
| Hiraoka, M; Nitta, J; Sawanobori, T; Sunami, A | 1 |
| Camm, AJ; Garratt, CJ; Griffith, MJ; Linker, NJ; Ward, DE | 1 |
| Akiyama, K; Hashimoto, K | 1 |
| Roden, DM | 1 |
| Kato, R; Kawai, N; Matsushima, H; Okada, M; Sotobata, I; Tanahashi, Y; Yamamoto, S | 1 |
| Podrid, PJ | 2 |
| Keefe, DL; Miura, D; Somberg, JC | 1 |
| Cannon, NJ; Duff, HJ; Sheldon, RS | 1 |
| Aisaka, K; Hattori, Y; Hidaka, T; Ishihara, T; Satoh, F | 1 |
| Kawakubo, K; Murakawa, Y; Nozaki, A; Sugimoto, T; Toda, I | 1 |
| Bell, P; Martorana, M; Winslow, E | 1 |
| Hoffman, BF; Spinelli, W | 1 |
| Gorshkov, VA; Kirichenko, LL; Kurakina, TI; Mamaev, VI; Masenko, VP; Morozova, LM; Narynski, AK | 1 |
| Miyazaki, T; Nakamura, Y; Noya, K; Ogawa, S; You, S | 1 |
| Coraboeuf, E; Coulombe, A; Deroubaix, E; Escande, D | 1 |
| Somberg, J | 1 |
| Roden, DM; Siddoway, LA; Woosley, RL | 1 |
| Roy, D | 1 |
| Abrahamsen, AM; Gundersen, T; Rønnevik, PK | 1 |
| Hirai, K; Minematsu, R; Miyake, K; Shimizu, K; Takeo, S; Tanonaka, K | 1 |
| Ban, T; Kojima, M | 1 |
| Echt, DS; Roden, DM; Woosley, RL | 1 |
| Andersson, KE; Wettrell, G | 1 |
| Morganroth, J; Nestico, PF | 3 |
| Huang, SK; Marcus, FI | 1 |
| Wood, M | 1 |
| Proelss, HF; Townsend, TB | 1 |
| Light, RT; Onrot, J; Robertson, D; Robertson, RM; Tantengco, MV | 1 |
| Kates, RE | 2 |
| Frais, MA; Hafizullah, M; Jackson, NC; Kalra, PA; Reynolds, GW; Silke, B; Taylor, SH; Verma, SP | 1 |
| Baedeker, W; Barthel, P; Blömer, H; Goedel-Meinen, L; Hofmann, M; Schmidt, G | 1 |
| Hashimoto, Y; Hatta, M; Hattori, Y; Hirotsu, I; Ishihara, T; Kihara, T; Kitakaze, Y; Miyata, T; Nakamura, S; Takahama, K | 1 |
| Hatta, M; Hattori, Y; Hirose, N; Hirotsu, I; Ishihara, T; Kihara, T; Satoh, F | 1 |
| Ishigaki, S; Sakata, K; Sakata, M | 1 |
| Elharrar, V | 1 |
| Enk, B; Fridberg, M; Lindeneg, O; Pedersen-Bjergaard, O; Svendsen, TL | 1 |
| Angelo, HR; Bonde, J; Burgaard, P; Graudal, N; Jensen, NM; Kampmann, JP; Pedersen, LE | 1 |
| Ikeda, K; Kamakura, S; Matsuhisa, M; Ohe, T; Shimomura, K; Yamamoto, K | 1 |
| Angelo, HR; Bonde, J; Kampmann, JP; Kastrup, J | 1 |
| Hirosawa, K; Kasanuki, H; Onishi, S | 1 |
| Collignon, P; Legrand, V | 1 |
| Hashimoto, K; Imai, S; Shibuya, T | 1 |
| Aisaka, K; Hamasaki, S; Hidaka, T; Inomata, N; Ishihara, T; Morita, M | 1 |
| Hashimoto, S; Kanazawa, T; Miura, M; Ono, Y | 1 |
| Junien, JL; Lakatos, CR; Tine, J | 1 |
| Hauswirth, O; Singh, BN | 1 |
| Lomanto, B; Rossi, A; Sanna, GP | 1 |
| Opie, LH | 1 |
| Schmitz, W | 1 |
| Attuel, P; Coumel, P; Georgiopoulos, G; Halkidis, H; Leclercq, JF; Maisonblanche, P | 1 |
| Reid, PR; Vlay, SC | 1 |
| Elkayam, U; Frishman, W; Rotmensch, HH | 1 |
| Hillis, WS; Whiting, B | 1 |
| Prystowsky, EN | 1 |
| Somberg, JC | 1 |
| Doherty, JU; Josephson, ME; Kienzle, MG; Williams, PD; Zygmont, D | 1 |
| Jahrmärker, H; Theisen, K | 1 |
| Lalka, D; McNamara, PJ; Pieper, JA; Slaughter, RL; Wyman, MG | 1 |
| Howanitz, JH; Howanitz, PJ | 1 |
| Mohiuddin, SM; Ross, WB | 1 |
| Lüderitz, B | 1 |
| Sevick, RJ; Wyse, DG | 1 |
| Rosen, MR; Wit, AL | 1 |
| Block, PJ; Winkle, RA | 1 |
| DePace, NL; Morganroth, J; Nestico, PF | 1 |
| Allen-Narker, RA; Barritt, DW; Goodfellow, RM; Jordan, SC; Marshall, AJ; Roberts, CJ | 1 |
| Bettini, R; Dal Forno, P; Disertori, M; Furlanello, F; Gramegna, L; Inama, G; Vergara, G | 1 |
| Bexton, RS; Burnett, PJ; Camm, AJ; Debbas, NM; Hellestrand, KJ; Milne, JR | 1 |
| Cairns, JA; Gent, M; Gupta, RN; Johnson, AL; Johnston, M; Kumana, CR; Rambihar, VS; Tanser, PH; Wildeman, RA | 1 |
| Bricaud, H; Lévy, RH; Lévy, S | 1 |
| Cho, YW; Kuemmerle, HP; Singh, BN | 1 |
| Flouvat, B | 1 |
| Mouselimis, N; Wester, HA | 1 |
| Hirosawa, K; Kasanuki, H; Ohnishi, S | 1 |
| Hashimoto, K; Imai, S; Satoh, H; Shibuya, T | 2 |
| Bailey, JC; Nattel, S | 1 |
| Buxton, AE; Josephson, ME; Sadowski, LM; Waxman, HL | 1 |
| Chiariello, M; Condorelli, M; Ferro, G; Tari, MG; Ungaro, B; Vigorito, C | 1 |
| Arensberg, D; Felner, JM; Stanford, JL | 1 |
| Bowers, GN; Flood, JG; McComb, RB | 1 |
| Dreifus, LS; Morganroth, J | 1 |
| Moses, HW; Yu, PN | 1 |
| Condorelli, M; De Luca, N; Rengo, F; Ricciardelli, B; Sacca', L; Trimarco, B; Volpe, M | 1 |
| Garfein, OB | 1 |
| Abbott, JA | 1 |
| Drake, CE | 1 |
| Chen, SH; Kabra, PM; Marton, LJ | 1 |
| Affrime, MB; Lowenthal, DT | 1 |
| Ego, Y; Fujita, T; Hayashi, K; Kito, Y; Kosakai, Y; Koyanagi, H; Kozuka, T; Manabe, H; Naito, Y; Nishimura, T; Ohara, K | 1 |
| McEniry, DW; Skorton, DJ | 1 |
| Hasin, Y; Rogel, S; Sarel, O | 1 |
| Fukuzaki, H; Hatani, M; Hori, Y; Imai, N; Nadai, T; Okamoto, R; Takano, S; Toh, H | 1 |
| Bonaduce, D; Condorelli, M; D'Ascia, C; De Luca, N; Rengo, F; Ricciardelli, B; Trimarco, B; Volpe, M | 1 |
| Abbott, JA; Cheitlin, MD; Desai, J; Holford, N; Peters, RW; Remedios, P; Scheinman, MM | 1 |
| Rothman, MT | 1 |
| Kötter, V; Linderer, T; Schröder, R | 1 |
| Carlsson, B; Drvota, V; Häggblad, J; Sylvén, C | 1 |
| Haruno, A; Hashimoto, K | 1 |
| Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Sakai, R; Shirayama, T | 1 |
| Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Sakai, R; Shirayama, T; Yamahara, Y | 1 |
| Kato, H; Kodama, I; Lee, JK; Nonokawa, M; Takanaka, C; Toyama, J; Yabe, S | 1 |
| Lee, JK; Nonokawa, M; Sugiyama, T; Takanaka, C; Yame, S | 1 |
| Akaishi, M; Handa, S; Iwanaga, S; Ogawa, S; Okada, Y; Sadanaga, T; Tsutsumi, N; Yoshikawa, T | 1 |
| Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Omori, I; Sakai, R; Yamahara, Y | 1 |
| Akaike, N; Inomata, N; Ishihara, T; Ohno, T | 1 |
| Aizawa, Y; Mitamura, H; Miyazaki, T; Miyoshi, S; Ogawa, S; Soejima, K | 1 |
| Fujiki, A; Inoue, H; Tani, M; Yoshida, S | 1 |
| Barré, J; d'Athis, P; Duché, JC; Hervé, F; Marché, C; Tillement, JP | 1 |
| Adgey, AA; Allen, JD; Devine, AB; Stewart, AJ | 1 |
| Aupetit, JF; Faucon, G; Loufoua-Moundanga, J; Timour, Q | 1 |
| Kondo, T; Kubota, I; Tachibana, H; Tomoike, H; Yamaki, M | 1 |
| Matsumori, A; Nishio, R; Nose, Y; Ono, K; Sasayama, S | 1 |
| Fernández del Pozo, B; Fernández, C; Pérez-Vizcaíno, F; Tamargo, J; Zaragozá, F | 1 |
| Baba, S; Funakoshi, M; Ishide, N; Iwabuchi, K; Katoh, H; Keitoku, M; Miura, M; Satoh, S; Shinozaki, T; Shirato, K; Suzuki, S; Takeuchi, M; Watanabe, J | 1 |
| Kikuchi, K; Nagai, T; Príborský, J; Takayama, K | 1 |
| Kubota, I; Tachibana, H; Tomoike, H; Watanabe, T; Yamaki, M | 2 |
| Kubota, I; Tachibana, H; Tomoike, H; Watanabe, T; Yamaki, M; Yamauchi, S | 2 |
| Hagihara, A; Hashimoto, K; Sugiyama, A | 1 |
| Izumi, T; Kitano, Y; Moriguchi, M; Niwano, S | 1 |
| Hayashi, Y; Hidaka, T; Inomata, N; Inoue, T; Komoriya, K | 1 |
| Aye, NN; Hashimoto, K; Miyamoto, S; Teramatsu, T; Zhu, B | 1 |
| Carboni, M; Chandra, R; Grant, AO; Keller, C; Starmer, CF | 1 |
| Abe, H; Hiraki, T; Ikeda, H; Imaizumi, T; Kumagai, K; Nakashima, H; Nakashima, Y; Oginosawa, Y; Saku, K | 1 |
| Imai, H; Matoba, Y; Nakagawa, M; Shiraishi, H; Shirayama, T; Yoshida, S | 1 |
| Ando, A; Hirai, M; Inden, Y; Isobe, S; Murohara, T; Nonokawa, M; Okada, M; Suzuki, A; Takada, Y; Tomita, Y | 1 |
| Endou, H; Enomoto, A; Hasannejad, H; Huang, XL; Jung, SH; Narikawa, S; Niwa, T; Onozato, ML; Takeda, M; Taki, K; Tojo, A | 1 |
| Fujimura, A; Sakamoto, K; Shiga, T; Tsuruoka, S; Wakaumi, M | 1 |
| Aizawa, Y; Chinushi, M; Hirono, T; Komura, S; Sugiura, H | 1 |
| Imai, T; Kajimoto, K; Kasanuki, H; Minami, Y | 1 |
33 review(s) available for lidocaine and disopyramide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Anti-arrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Anesthetics; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Dogs; Humans; Intraoperative Complications; Lidocaine; Mexiletine; Phenytoin; Procainamide; Succinylcholine | 1979 |
Rational basis of antiarrhythmic therapy: clinical pharmacology of commonly used antiarrhythmic drugs.
Topics: Action Potentials; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Disopyramide; Heart; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine; Sympatholytics; Time Factors | 1978 |
Pharmacokinetics of antiarrhythmic drugs.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Glycine; Half-Life; Injections, Intravenous; Kinetics; Lidocaine; Procainamide; Quinidine | 1978 |
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects].
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glycosides; Digitalis Glycosides; Disopyramide; Drug Interactions; Drug Synergism; Humans; Hypertension; Hypokalemia; Isoproterenol; Lidocaine; Monoamine Oxidase Inhibitors; Ouabain; Phenytoin; Prenylamine; Procainamide; Quinidine | 1976 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Death, Sudden; Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Random Allocation; Tocainide | 1985 |
The treatment of ventricular rhythm disturbances.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Electric Countershock; Electric Stimulation; Electrocardiography; Exercise Test; Flecainide; Heart Ventricles; Humans; Lidocaine; Phenytoin; Piperidines; Procainamide; Quinidine; Risk; Tachycardia; Tocainide; United States; Ventricular Fibrillation; Verapamil | 1986 |
Antiarrhythmic drug therapy. Recent advances and current status.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil | 1985 |
Clinical pharmacology of old and new antiarrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide | 1985 |
Antiarrhythmic drugs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium Channel Blockers; Cell Membrane; Disopyramide; Electrophysiology; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide | 1986 |
Effects of congestive heart failure on the pharmacokinetics and pharmacodynamics of antiarrhythmic agents.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Digitalis; Disopyramide; Drug Interactions; Encainide; Flecainide; Half-Life; Heart Failure; Hemodynamics; Humans; Kidney; Kinetics; Lidocaine; Liver; Piperidines; Plants, Medicinal; Plants, Toxic; Potassium; Procainamide; Quinidine; Regional Blood Flow; Tocainide | 1986 |
Cardiovascular drugs. I: Antidysrhythmic drugs.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Cardiovascular Agents; Disopyramide; Drug Interactions; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Tocainide; Verapamil | 1986 |
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil | 1986 |
Antiarrhythmic drug therapy of ventricular arrhythmias.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil | 1986 |
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors | 1986 |
Antiarrhythmic agents for chronic ventricular arrhythmias.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide | 1987 |
[Treatment of extrasystole (ventricular and atrial extrasystoles)].
Topics: Adrenergic beta-Antagonists; Ajmaline; Aniline Compounds; Benzyl Compounds; Cardiac Complexes, Premature; Disopyramide; Hemodynamics; Humans; Imidazoles; Lidocaine; Phenytoin; Procainamide; Propanolamines; Propranolol; Quinidine | 1974 |
Comparative mechanisms of action of antiarrhythmic drugs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Benzyl Compounds; Bretylium Compounds; Calcium; Carbamazepine; Chemical Phenomena; Chemistry; Diethylamines; Disopyramide; Heart; Humans; Imidazoles; Iodobenzoates; Lidocaine; Membrane Potentials; Phenyl Ethers; Phenytoin; Procainamide; Propylamines; Quinidine; Verapamil | 1974 |
[Electrophysiological classification of newer antiarrhythmic drugs (author's transl)].
Topics: Action Potentials; Adrenergic beta-Antagonists; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Quinidine; Sodium; Tocainide | 1980 |
Antiarrhythmic drug therapy during pregnancy.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Digitalis Glycosides; Disopyramide; Female; Fetus; Humans; Infant, Newborn; Lidocaine; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Tachycardia; Verapamil | 1983 |
Pharmacologic therapy of tachyarrhythmias in patients with Wolff-Parkinson-White syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ajmaline; Amiodarone; Anilides; Aprindine; Atrial Fibrillation; Benzofurans; Digitalis Glycosides; Disopyramide; Encainide; Female; Humans; Lidocaine; Male; Middle Aged; Procainamide; Quinidine; Tachycardia; Verapamil; Wolff-Parkinson-White Syndrome | 1983 |
Antiarrhythmic drug therapy for sustained ventricular tachycardia.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bethanidine; Calcium Channel Blockers; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Encainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Phenytoin; Piperidines; Procainamide; Quinidine; Tachycardia; Tocainide | 1984 |
[Medical treatment of extrasystole and tachycardia (author's transl)].
Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Digoxin; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1980 |
Antiarrhythmic drug monitoring.
Topics: Acecainide; Anti-Arrhythmia Agents; Disopyramide; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1981 |
Electropharmacology of antiarrhythmic drugs.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Electric Conductivity; Heart Atria; Heart Ventricles; Humans; Lidocaine; Membrane Potentials; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Quinidine; Tocainide; Verapamil | 1983 |
Hemodynamic effects of antiarrhythmic drugs.
Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide | 1983 |
Therapy with conventional antiarrhythmic drugs for ventricular arrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Heart Ventricles; Humans; Lidocaine; Procainamide; Propranolol; Quinidine; Tocainide | 1984 |
New insights into the drug treatment of ventricular arrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Disopyramide; Humans; Kinetics; Lidocaine; Procainamide; Propranolol; Quinidine; Tocainide | 1984 |
Metabolites of cardiac antiarrhythmic drugs: their clinical role.
Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Disopyramide; Encainide; Humans; Lidocaine; Piperidines; Procainamide; Quinidine | 1984 |
Antiarrhythmic agents and their use in therapy.
Topics: Acebutolol; Animals; Anti-Arrhythmia Agents; Digitalis Glycosides; Disopyramide; Humans; Lidocaine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1980 |
Antiarrhythmic drugs.
Topics: Anti-Arrhythmia Agents; Bretylium Tosylate; Disopyramide; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1980 |
Pharmacology of commonly used antiarrhythmic drugs and comments on the use of therapeutic drug monitoring.
Topics: Anti-Arrhythmia Agents; Disopyramide; Humans; Kinetics; Lidocaine; Procainamide; Propranolol; Quinidine | 1982 |
Intravenous antiarrhythmic drugs: newer aspects of therapy.
Topics: Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Hemodynamics; Humans; Injections, Intravenous; Lidocaine; Tachycardia; Verapamil | 1982 |
18 trial(s) available for lidocaine and disopyramide
| Article | Year |
|---|---|
Anti-dysrhythmic treatment in acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Atenolol; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Myocardial Infarction; Oxprenolol; Propranolol; Ventricular Fibrillation | 1979 |
Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Humans; Injections, Intravenous; Lidocaine; Middle Aged; Myocardial Infarction; Pyridines | 1979 |
Cardiac effects of disopyramide and lignocaine assessed by echocardiography [proceedings].
Topics: Disopyramide; Echocardiography; Heart; Humans; Lidocaine; Pyridines | 1979 |
Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia.
Topics: Adenosine; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Disopyramide; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Flecainide; Humans; Hypotension; Injections, Intravenous; Lidocaine; Middle Aged; Recurrence; Sotalol; Tachycardia | 1990 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Death, Sudden; Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Random Allocation; Tocainide | 1985 |
Tolerability and antiarrhythmic efficacy of disopyramide compared to lignocaine in selected patients with suspected acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Arrhythmias, Cardiac; Disopyramide; Drug Therapy, Combination; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Random Allocation | 1987 |
Comparative haemodynamic effects of intravenous lignocaine, disopyramide and flecainide in uncomplicated acute myocardial infarction.
Topics: Adult; Aged; Disopyramide; Flecainide; Hemodynamics; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Myocardial Infarction; Prospective Studies | 1986 |
[Effect of class I anti-arrhythmia agents on the signal-averaged ECG].
Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Clinical Trials as Topic; Coronary Disease; Disopyramide; Electrocardiography; Female; Flecainide; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Random Allocation; Signal Processing, Computer-Assisted; Tachycardia; Tocainide | 1988 |
[Disopyramide and lignocaine in the treatment of ventricular arrhythmia in patients with acute ischemic heart disease].
Topics: Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Disopyramide; Double-Blind Method; Humans; Lidocaine; Myocardial Infarction | 1986 |
Prophylaxis against ventricular arrhythmias in suspected acute myocardial infarction: a comparison of tocainide and disopyramide.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Tocainide; Ventricular Fibrillation | 1984 |
A placebo-controlled study to determine the efficacy of oral disopyramide phosphate for the prophylaxis of ventricular dysrhythmias after acute myocardial infarction.
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Placebos; Pyridines | 1982 |
[The effect of anti-arrhythmic drugs on myocardial function (author's transl)].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Coronary Disease; Depression, Chemical; Disopyramide; Echocardiography; Humans; Lidocaine; Mexiletine; Middle Aged; Myocardial Contraction; Placebos; Propafenone; Propiophenones; Tocainide | 1982 |
Disopyramide and mexiletine: which is the agent of choice in the long term-oral treatment of lidocaine-responsive arrhythmias? Efficacy comparison in a randomized trial.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; Electrocardiography; Humans; Lidocaine; Mexiletine; Propylamines; Pyridines; Random Allocation | 1980 |
Disopyramide and lignocaine. A comparison of cardiac effects using echocardiography.
Topics: Adult; Blood Pressure; Cardiac Output; Disopyramide; Echocardiography; Heart; Heart Rate; Humans; Lidocaine; Male; Pyridines; Stroke Volume; Systole | 1980 |
Kinetics of frequency-dependent conduction delay by class I antiarrhythmic drugs in human atrium.
Topics: Anti-Arrhythmia Agents; Aprindine; Cardiac Pacing, Artificial; Disopyramide; Electrophysiology; Female; Heart Atria; Heart Conduction System; Humans; Kinetics; Lidocaine; Male; Mexiletine; Middle Aged; Sodium Channels | 1995 |
Electrophysiologic mechanisms of adverse effects of class I antiarrhythmic drugs (cibenzoline, pilsicainide, disopyramide, procainamide) in induction of atrioventricular re-entrant tachycardia.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Disopyramide; Electrophysiology; Female; Heart Conduction System; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Procainamide; Tachycardia, Atrioventricular Nodal Reentry; Wolff-Parkinson-White Syndrome | 1996 |
Single oral administration of pilsicainide versus infusion of disopyramide for termination of paroxysmal atrial fibrillation: a multicenter trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Circadian Rhythm; Disopyramide; Female; Heart Rate; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome | 2000 |
Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
Topics: Aged; Anti-Asthmatic Agents; Chronic Disease; Disopyramide; Exercise; Exercise Test; Female; Heart Ventricles; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Radionuclide Imaging; Tachycardia, Ventricular; Treatment Outcome; Ventricular Dysfunction, Left | 2004 |
145 other study(ies) available for lidocaine and disopyramide
| Article | Year |
|---|---|
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship | 1993 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics | 2005 |
Molecular characteristics for solid-state limited solubility.
Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Drug therapy of tachyarrhythmias (author's transl)].
Topics: Action Potentials; Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil | 1978 |
Disopyramide--an effective treatment for lignocaine resistant ventricular dysrhythmias.
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Female; Humans; Lidocaine; Male; Myocardial Infarction; Pyridines; Tachycardia; Ventricular Fibrillation | 1979 |
Preventing ventricular arrhythmias in ischemic heart disease.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Humans; Lidocaine; Nitroglycerin; Procainamide; Quinidine | 1979 |
Drugs used in the care of the cardiac patient.
Topics: Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Atropine; Bretylium Tosylate; Cardiac Glycosides; Cardiovascular Diseases; Digitalis Glycosides; Disopyramide; Diuretics; Dose-Response Relationship, Drug; Humans; Isoproterenol; Lidocaine; Myocardial Contraction; Propranolol; Quinidine | 1978 |
Treatment of arrhythmias in the Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Atrial Fibrillation; Disopyramide; Humans; Injections, Intravenous; Lidocaine; Procainamide; Pyridines; Quinidine; Tachycardia; Ventricular Fibrillation; Wolff-Parkinson-White Syndrome | 1979 |
Series on pharmacology in practice. 2. Antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Bretylium Compounds; Disopyramide; Humans; Lidocaine; Metoprolol; Procainamide; Propranolol; Quinidine; Verapamil | 1979 |
Disopyramide phosphate: is it just another quinidine.
Topics: Action Potentials; Animals; Disopyramide; Dogs; Heart; In Vitro Techniques; Lidocaine; Membrane Potentials; Papillary Muscles; Purkinje Fibers; Pyridines; Quinidine | 1978 |
How useful are serum levels of cardiac drugs?
Topics: Anti-Arrhythmia Agents; Digitalis Glycosides; Disopyramide; Heart Diseases; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1978 |
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses.
Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1978 |
Liquid chromatography in the monitoring of plasma levels of antiarrhythmic drugs.
Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Chromatography, High Pressure Liquid; Disopyramide; Lidocaine; Procainamide; Quinidine | 1978 |
Therapy with antiarrhythmic drugs.
Topics: Acetylation; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Heart Failure; Humans; Indocyanine Green; Infusions, Parenteral; Lidocaine; Liver; Lupus Erythematosus, Systemic; Myocardial Infarction; Procainamide | 1978 |
Some effects of disopyramide and its N-dealkylated metabolite on isolated nerve and cardiac muscle.
Topics: Action Potentials; Animals; Dealkylation; Disopyramide; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Lidocaine; Myocardial Contraction; Nervous System; Neural Conduction; Procainamide; Propranolol; Pyridines; Quinidine; Rats | 1978 |
Electrode-catheter arrhythmia induction in the selection and assessment of antiarrhythmic drug therapy for recurrent ventricular tachycardia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Drug Evaluation; Electric Countershock; Electrocardiography; Female; Follow-Up Studies; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Monitoring, Physiologic; Phenytoin; Procainamide; Propranolol; Quinidine; Recurrence; Tachycardia | 1978 |
Recurrent sustained ventricular tachycardia 3. Role of the electrophysiologic study in selection of antiarrhythmic regimens.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Drug Evaluation; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Female; Follow-Up Studies; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Phenytoin; Procainamide; Quinidine; Recurrence; Tachycardia | 1978 |
Treatment of cardiac arrhythmias. Part II--The drugs.
Topics: Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Electric Countershock; Humans; Lidocaine; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine | 1978 |
Observations on the effects of selected antiarrhythmic drugs on mammalian cardiac purkinje fibers with two levels of steady-state potential: influences of lidocaine, phenytoin, propranolol, disopyramide and procainamide on repolarization, action potential
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Heart Conduction System; In Vitro Techniques; Lidocaine; Membrane Potentials; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Sheep; Time Factors | 1978 |
Prevention of ventricular arrhythmias after myocardial infarction.
Topics: Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Propranolol; Quinidine; Ventricular Fibrillation | 1977 |
Disopyramide in a case of recurrent ventricular fibrillation.
Topics: Aged; Disopyramide; Humans; Lidocaine; Male; Pyridines; Recurrence; Ventricular Fibrillation | 1976 |
Mechanism of action of antidysrhythmic drugs on ventricular conduction as studied with intramural electrodes.
Topics: Ajmaline; Animals; Disopyramide; Dogs; Electrocardiography; Heart Conduction System; Hydroxyzine; Lidocaine; Oxprenolol; Phenytoin; Propranolol; Purkinje Fibers; Quinidine; Verapamil | 1975 |
Effects of disopyramide phosphate on ventricular arrhythmias in experimental myocardial infarction.
Topics: Animals; Arrhythmias, Cardiac; Bundle of His; Disopyramide; Dogs; Electrocardiography; Female; Heart Rate; Lidocaine; Male; Myocardial Infarction; Pyridines; Stimulation, Chemical; Time Factors | 1976 |
Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs.
Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Dinitrophenols; Disopyramide; Flecainide; Glyburide; Guinea Pigs; Heart Ventricles; Imidazoles; Lidocaine; Mexiletine; Myocardium; Piperidines; Potassium; Procainamide; Pyridines | 1992 |
Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs.
Topics: Animals; Cells, Cultured; Disopyramide; Electric Conductivity; Heart; In Vitro Techniques; Ion Channel Gating; Lidocaine; Membrane Potentials; Myocardium; Rabbits; Sodium; Sodium Channels | 1992 |
Combined class I antiarrhythmic agents have differential effects on tonic and use dependent block of maximum rate of depolarisation of action potentials in guinea pig cardiac muscle.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aprindine; Disopyramide; Drug Combinations; Guinea Pigs; Lidocaine; Mexiletine; Myocardium; Quinidine; Sodium Channels | 1992 |
[Clinical significance of the use-dependent sodium channel block and reverse use-dependent potassium channel block of class I and class III antiarrhythmic agents and their values to predict drug efficacy].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography, Ambulatory; Electrophysiology; Exercise Test; Humans; Lidocaine; Mexiletine; Middle Aged; Potassium Channels; Sodium Channels | 1992 |
[Estimation of depressant effects of class I antiarrhythmic drugs on intraventricular conduction--rate-dependent effects on QRS duration].
Topics: Anti-Arrhythmia Agents; Aprindine; Depression, Chemical; Disopyramide; Electrocardiography; Flecainide; Heart Conduction System; Heart Rate; Humans; Lidocaine; Mexiletine; Sodium Channels; Ventricular Function | 1992 |
Correlation between the inhibitory effects of basic drugs on the uptake of cardiac glycosides and taurocholate by isolated rat hepatocytes.
Topics: Animals; Chlorpromazine; Dipyridamole; Disopyramide; Drug Interactions; In Vitro Techniques; Lidocaine; Liver; Male; Nifedipine; Ouabain; Propranolol; Quinidine; Rats; Rats, Wistar; Sodium; Taurocholic Acid; Verapamil | 1992 |
Modification by hypoxia, hyperkalaemia and acidosis of the cardiac electrophysiological effects of a range of antiarrhythmic drugs.
Topics: Acidosis; Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Electrophysiology; Heart; Hyperkalemia; Hypoxia; In Vitro Techniques; Lidocaine; Propanolamines; Propranolol; Purkinje Fibers; Sheep; Verapamil | 1992 |
Differential effects on action potential duration of class IA, B and C antiarrhythmic drugs: modulation by stimulation rate and extracellular K+ concentration.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Flecainide; Heart Rate; In Vitro Techniques; Lidocaine; Potassium Channels; Purkinje Fibers; Sodium Channels | 1991 |
Electrophysiological effects of sodium channel blockers on guinea pig left atrium.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aprindine; Atrial Function; Atrial Function, Left; Diastole; Disopyramide; Electrophysiology; Female; Flecainide; Guinea Pigs; Heart; Heart Atria; Kinetics; Lidocaine; Male; Sodium Channels | 1991 |
Two components of use-dependent block of Na+ current by disopyramide and lidocaine in guinea pig ventricular myocytes.
Topics: Animals; Disopyramide; Electric Stimulation; Electrophysiology; Guinea Pigs; Heart Ventricles; Hydrogen-Ion Concentration; Lidocaine; Myocardium; Sodium Channels | 1991 |
Membrane stabilising properties of the selective 5-HT2 receptor agonist, (+/-)-DOI.
Topics: Action Potentials; Amphetamines; Animals; Disopyramide; Dose-Response Relationship, Drug; Lidocaine; Male; Neural Conduction; Propranolol; Rana temporaria; Sciatic Nerve; Serotonin Antagonists | 1991 |
Antiarrhythmic and cardiovascular profiles of the fused indole compound (3aR,12R,12aR,12bS)-12-amino-2,3,3a,4,11,12,12a,12b-octahydro-10-hydrox yisoquino [2,1,8-lma]carbazol-5(1H)-one hydrochloride 1.5 hydrate.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbazoles; Chloroform; Disopyramide; Dogs; Female; Flecainide; Heart; Heart Conduction System; Hemodynamics; Isoquinolines; Lidocaine; Male; Mexiletine; Mice; Mice, Inbred ICR; Myocardial Contraction; Ouabain | 1991 |
Mechanisms of the anticholinergic effect of SUN 1165 in comparison with flecainide, disopyramide and quinidine in single atrial myocytes isolated from guinea-pig.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Flecainide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Myocardium; Parasympatholytics; Potassium Channels; Quinidine; Receptors, Cholinergic | 1991 |
Combined effects of different class I antiarrhythmic agents on maximum rate of depolarization (Vmax) of action potentials in guinea-pig papillary muscles.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Drug Interactions; Electric Stimulation; Guinea Pigs; Kinetics; Lidocaine; Muscle, Smooth, Vascular; Papillary Muscles | 1991 |
Effects of lidocaine, disopyramide and verapamil on the in vivo triggered ventricular arrhythmia in digitalized canine heart.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis Glycosides; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Lidocaine; Verapamil | 1990 |
Antiarrhythmic drugs. Clinical pharmacology of the old and the new agents.
Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden; Delayed-Action Preparations; Disopyramide; Heart Arrest; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Resuscitation; Tocainide | 1985 |
[Gated blood pool imaging in the diagnosis and management of arrhythmia].
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiac Output; Disopyramide; Electrocardiography; Heart Ventricles; Humans; Lidocaine; Myocardial Contraction; Pacemaker, Artificial; Radionuclide Imaging; Technetium; Wolff-Parkinson-White Syndrome | 1985 |
A receptor for type I antiarrhythmic drugs associated with rat cardiac sodium channels.
Topics: Animals; Anti-Arrhythmia Agents; Batrachotoxins; Disopyramide; Ion Channels; Lidocaine; Male; Myocardium; Rats; Receptors, Drug; Sodium; Stereoisomerism; Tocainide | 1987 |
Effect of SUN 1165, a new potent antiarrhythmic agent, on the kinetics of rate-dependent block of Na channels and ventricular conduction of extrasystoles.
Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Complexes, Premature; Disopyramide; Guinea Pigs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Ion Channels; Lidocaine; Male; Mexiletine; Papillary Muscles; Piperidines; Sodium | 1988 |
Effects of antiarrhythmic drugs on the repetitive extrasystole threshold and the ventricular fibrillation threshold.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Disopyramide; Dogs; Heart; Lidocaine; Mexiletine; Procainamide; Ventricular Fibrillation | 1989 |
Electrophysiologic effects of Org 7797, a new steroidal antiarrhythmic agent: comparison with class 1a, 1b, and 1c drugs.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Electric Stimulation; Estrenes; Female; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Propafenone; Purkinje Fibers; Sodium Channels; Swine | 1989 |
Mechanisms of termination of reentrant atrial arrhythmias by class I and class III antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Electrocardiography; Flecainide; Heart Conduction System; Heart Rate; Lidocaine; Piperidines; Propafenone; Sotalol | 1989 |
Platelet aggregation and prostaglandin metabolites in the blood of patients with ischaemic heart disease during antiarrhythmic treatment.
Topics: Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; Coronary Disease; Disopyramide; Female; Humans; Lidocaine; Male; Middle Aged; Nitroglycerin; Phenothiazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins | 1989 |
[Antiarrhythmic drug therapy for arrhythmogenic right ventricular dysplasia].
Topics: Adult; Cardiac Catheterization; Cardiomyopathies; Disopyramide; Drug Evaluation; Echocardiography; Electrocardiography; Heart Ventricles; Humans; Lidocaine; Male | 1989 |
Comparative effects of three class I antiarrhythmic drugs on plateau and pacemaker currents of sheep cardiac Purkinje fibres.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Channels; Disopyramide; Heart Conduction System; Lidocaine; Membrane Potentials; Potassium Channels; Propylamines; Purkinje Fibers; Pyridines; Sheep; Sodium Channels; Tetrodotoxin | 1988 |
Antiarrhythmic drug therapy (Part 1). Benefits and hazards.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Electrocardiography; Electrophysiology; Heart; Humans; Lidocaine; Procainamide; Quinidine | 1985 |
Beneficial effects of lidocaine and disopyramide on oxygen-deficiency-induced contractile failure and metabolic disturbance in isolated rabbit hearts.
Topics: Adenosine Triphosphate; Animals; Body Water; Calcium; Cell Membrane Permeability; Creatine Kinase; Disopyramide; Heart; In Vitro Techniques; Lidocaine; Male; Myocardial Contraction; Myocardium; Oxygen; Phosphocreatine; Rabbits | 1989 |
Nicorandil shortens action potential duration and antagonises the reduction of Vmax by lidocaine but not by disopyramide in guinea-pig papillary muscles.
Topics: Action Potentials; Animals; Disopyramide; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Niacinamide; Nicorandil; Papillary Muscles; Vasodilator Agents | 1988 |
Simultaneous liquid-chromatographic determination of five antiarrhythmic drugs and their major active metabolites in serum.
Topics: Anti-Arrhythmia Agents; Buffers; Chromatography, High Pressure Liquid; Disopyramide; Ethylamines; Heart Diseases; Humans; Hydrogen-Ion Concentration; Lidocaine; Procainamide; Quinidine; Temperature; Tocainide | 1986 |
Orthostatic hypotension: clinical spectrum and approach to treatment.
Topics: Adult; Aged; Amiodarone; Disopyramide; Female; Flecainide; Humans; Hypotension, Orthostatic; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Quinidine; Sympathomimetics; Tocainide | 1986 |
Metabolites of antiarrhythmic drugs: are they clinically important?
Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Procainamide; Quinidine | 1986 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 1st communication: effect on the central nervous system.
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Body Temperature; Catalepsy; Cats; Central Nervous System; Chemical Phenomena; Chemistry; Disopyramide; Dogs; Electroencephalography; Female; Hypothermia; Lidocaine; Male; Mexiletine; Mice; Motor Activity; Muscle Relaxation; Pain; Rabbits; Rats; Rats, Inbred Strains; Seizures; Tremor; Vomiting | 1988 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 2nd communication: effect on the peripheral nervous system and peripheral organs.
Topics: Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Capillary Permeability; Chemical Phenomena; Chemistry; Digestive System; Disopyramide; Endocrine Glands; Female; Gastric Mucosa; Gastrointestinal Motility; Guinea Pigs; Ileum; Lidocaine; Male; Mexiletine; Mice; Peripheral Nerves; Pregnancy; Pupil; Rabbits; Rats; Rats, Inbred Strains; Trachea; Urinary Bladder; Urogenital System; Uterus; Vas Deferens | 1988 |
Distribution of lidocaine and disopyramide in human blood and tissue, a case report of death caused by spinal anesthesia.
Topics: Anesthesia, Spinal; Animals; Brain; Child; Disopyramide; Female; Heart Diseases; Humans; Kidney; Lidocaine; Male; Rats; Rats, Inbred WKY; Respiratory Insufficiency; Tissue Distribution | 1988 |
Recovery from use-dependent block of Vmax and restitution of action potential duration in canine cardiac Purkinje fibers.
Topics: Action Potentials; Animals; Disopyramide; Dogs; Electrophysiology; Heart Conduction System; Lidocaine; Mexiletine; Microelectrodes; Purkinje Fibers; Sodium; Tetrodotoxin | 1988 |
Displacement of lidocaine from human plasma proteins by disopyramide.
Topics: Aged; Binding, Competitive; Blood Proteins; Disopyramide; Female; Humans; Lidocaine; Male; Middle Aged; Orosomucoid | 1987 |
[Electrophysiological studies in 2 patients with chronic persistent atrial tachycardia].
Topics: Adult; Disopyramide; Electrocardiography; Electrophysiology; Female; Humans; Lidocaine; Middle Aged; Procainamide; Tachycardia | 1987 |
A HPLC method for the simultaneous determination of disopyramide, lidocaine and their monodealkylated metabolites.
Topics: Chromatography, High Pressure Liquid; Disopyramide; Humans; Lidocaine | 1986 |
The usefulness of electrophysiological-pharmacologic studies in the long-term therapy of paroxysmal tachycardias.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Chromatography, High Pressure Liquid; Disopyramide; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Quinidine; Tachycardia, Paroxysmal; Time Factors; Tocainide; Verapamil | 1985 |
Haemodynamic effects of class I antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Disopyramide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide | 1985 |
Cardiovascular and respiratory effects of antiarrhythmic drugs on conscious beagles.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Disopyramide; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Lidocaine; Male; Phenytoin; Procainamide; Respiration; Verapamil | 1985 |
N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate (SUN 1165): a new potent and long-acting antiarrhythmic agent.
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell Membrane; Coronary Circulation; Coronary Vessels; Disopyramide; Dogs; Epinephrine; Female; Guinea Pigs; Halothane; In Vitro Techniques; Lidocaine; Male; Myocardial Contraction; Ouabain; Papillary Muscles | 1985 |
Comparative effect of imolamine, lidocaine and disopyramide on experimental rhythm disorders and auriculoventricular conduction.
Topics: Aconitum; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Complexes, Premature; Diethylamines; Disopyramide; Dogs; Electrocardiography; Epinephrine; Female; Guinea Pigs; Heart Block; Heart Conduction System; Heart Rate; Imines; Lidocaine; Male; Oxadiazoles; Papaverine; Pyridines; Rats; Strophanthins | 1974 |
[Electrophysiological principles of the action of antiarrhythmia agents].
Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Electrophysiology; Heart; Humans; Lidocaine; Procainamide; Quinidine | 1974 |
Drugs and the heart. IV. Antiarrhythmic agents.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Heart Conduction System; Hemodynamics; Humans; Lidocaine; Mexiletine; Procainamide; Quinidine; Verapamil | 1980 |
[Effects of anti-arrhythmia agents on heart rate. Significance and importance].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Disopyramide; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lidocaine; Propafenone; Propiophenones; Quinidine; Verapamil | 1981 |
Ventricular ectopy: etiology, evaluation, and therapy.
Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Echocardiography; Electric Stimulation; Humans; Ischemia; Lidocaine; Myocardial Infarction; Nitrates; Pacemaker, Artificial; Phenytoin; Procainamide; Radionuclide Imaging; Risk | 1982 |
Antiarrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil | 1983 |
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil | 1984 |
Factors influencing serum protein binding of lidocaine in humans.
Topics: Acecainide; Blood Proteins; Bupivacaine; Disopyramide; Humans; Lidocaine; Orosomucoid; Procainamide; Propranolol; Protein Binding; Quinidine; Serum Albumin | 1981 |
Antiarrhythmic therapy: new additions and future expectations.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Bretylium Tosylate; Disopyramide; Encainide; Humans; Lidocaine; Mexiletine; Tocainide; Verapamil | 1983 |
[Drug therapy of arrhythmia in coronary cardiopathy].
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Electrocardiography; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Tachycardia; Tocainide | 1983 |
Long-term management of arrhythmogenic right ventricular dysplasia.
Topics: Adolescent; Cardiomegaly; Cardiomyopathies; Disopyramide; Electrocardiography; Heart Ventricles; Humans; Lidocaine; Male; Tachycardia; Tocainide | 1983 |
Worsening of arrhythmias during pharmacological treatment.
Topics: Adolescent; Adult; Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Child; Disopyramide; Female; Follow-Up Studies; Humans; Lidocaine; Male; Middle Aged; Nadolol; Piperidines; Propafenone; Propanolamines; Propiophenones; Tocainide | 1984 |
Class 1 antiarrhythmic drugs--characteristic electrocardiographic differences when assessed by atrial and ventricular pacing.
Topics: Action Potentials; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Coronary Disease; Disopyramide; Electrocardiography; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged; Piperidines | 1984 |
[Pharmacokinetics of anti-arrhythmics. 2. Clinical applications].
Topics: Administration, Oral; Anti-Arrhythmia Agents; Disopyramide; Humans; Kinetics; Lidocaine; Perfusion; Phenytoin; Procainamide; Propranolol; Quinidine | 1980 |
Clinical pharmacology of antiarrhythmic drugs: a review and overview, part II.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Propranolol; Tocainide | 1981 |
[Determination of plasma concentrations of anti-arrhythmia agents].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biological Availability; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine | 1981 |
Availability of electrophysiological approach to the selection and assessment of antiarrhythmic drugs for recurrent ventricular tachycardia.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Disopyramide; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Procainamide; Recurrence; Tachycardia; Verapamil | 1983 |
Quantitative analysis of the antiarrhythmic effect of drugs on canine ventricular arrhythmias by the determination of minimum effective plasma concentrations.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Dogs; Female; Lidocaine; Male; Mexiletine; Phenytoin; Verapamil | 1983 |
Time course of the electrophysiological effects of quinidine on canine cardiac Purkinje fibers: concentration dependence and comparison with lidocaine and disopyramide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electrophysiology; Female; Heart Conduction System; Kinetics; Lidocaine; Male; Purkinje Fibers; Quinidine | 1983 |
The response to procainamide during electrophysiologic study for sustained ventricular tachyarrhythmias predicts the response to other medications.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Female; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Phenytoin; Procainamide; Quinidine; Tachycardia | 1983 |
Intropic effects of several antiarrhythmic drugs.
Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Blood Pressure; Bunaftine; Coronary Disease; Disopyramide; Heart Rate; Hemodynamics; Humans; Lidocaine; Mexiletine; Middle Aged; Myocardial Contraction; Phenytoin; Procainamide | 1983 |
Antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Heart Conduction System; Humans; Lidocaine; Phenytoin; Procainamide; Quinidine | 1980 |
Simultaneous liquid-chromatographic determination of three antiarrhythmic drugs: disopyramide, lidocaine, and quinidine.
Topics: Chromatography, High Pressure Liquid; Disopyramide; Drug Interactions; Fluorometry; Humans; Immunoenzyme Techniques; Lidocaine; Pyridines; Quinidine | 1980 |
Cardiac drug overdose.
Topics: Arrhythmias, Cardiac; Bretylium Compounds; Cardiovascular Agents; Cardiovascular Diseases; Digoxin; Disopyramide; Humans; Hypotension; Lidocaine; Liver; Phenytoin; Procainamide; Propranolol; Quinidine; Vasodilator Agents | 1982 |
Canine-effective plasma concentrations of antiarrhythmic drugs on the two-stage coronary ligation arrhythmia.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyramide; Dogs; Dose-Response Relationship, Drug; Isoquinolines; Lidocaine; Ligation; Phenytoin; Propanolamines; Verapamil | 1982 |
Liquid-chromatographic determination of antidysrhythmic drugs: procainamide, lidocaine, quinidine, disopyramide, and propranolol.
Topics: Anti-Arrhythmia Agents; Chromatography, Liquid; Disopyramide; Humans; Lidocaine; Procainamide; Propranolol; Quinidine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1981 |
Cardiovascular drugs for the geriatric patient.
Topics: Aged; Aging; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular Physiological Phenomena; Digoxin; Disopyramide; Humans; Intestinal Absorption; Kidney; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1981 |
[Comparative effects of disopyramide and lidocaine on negative inotropic action--evaluation by multigated RI angiography (author's transl)].
Topics: Adult; Aged; Cardiac Output; Child; Disopyramide; Female; Heart; Hemodynamics; Humans; Lidocaine; Male; Middle Aged; Pyridines; Radionuclide Imaging | 1981 |
Adverse reactions to cardiovascular drugs (Part II--Antiarrhythmic agents).
Topics: Anti-Arrhythmia Agents; Disopyramide; Lidocaine; Procainamide; Quinidine | 1981 |
Myocardial conduction time and antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Dogs; Electrophysiology; Heart Conduction System; Lidocaine; Quinidine; Ventricular Function; Verapamil | 1981 |
Studies on the preventive method of lowered ventricular fibrillation threshold during experimental acute myocardial infarctions. A comparison between disopyramide phosphate and lidocaine.
Topics: Animals; Disease Models, Animal; Disopyramide; Dogs; Dose-Response Relationship, Drug; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Myocardial Infarction; Pyridines; Ventricular Fibrillation | 1981 |
[Efficacy of disopyramide and mexiletine per os in the chronic treatment of ventricular arrhythmias sensitive to lidocaine].
Topics: Arrhythmias, Cardiac; Disopyramide; Humans; Lidocaine; Mexiletine; Middle Aged; Propylamines; Pyridines | 1981 |
Effects of antiarrhythmic drugs on atrioventricular conduction in patients with acute myocardial infarction.
Topics: Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Digoxin; Disopyramide; Heart Block; Heart Conduction System; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Procainamide; Propranolol; Quinidine; Time Factors | 1980 |
Prolonged QT interval, atrioventricular block, and torsade de pointes after antiarrhythmic therapy.
Topics: Aged; Disopyramide; Electrocardiography; Female; Heart; Heart Block; Humans; Lidocaine; Pyridines; Tachycardia; Ventricular Fibrillation | 1980 |
Effects of disopyramide on systemic and coronary hemodynamics and myocardial metabolism in patients with coronary artery disease: comparison with lidocaine.
Topics: Adult; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Disease; Diastole; Disopyramide; Female; Heart Rate; Hemodynamics; Humans; Lidocaine; Male; Middle Aged; Myocardium; Pyridines; Stroke Volume | 1980 |
Amiodarone is a dose-dependent noncompetitive and competitive inhibitor of T3 binding to thyroid hormone receptor subtype beta 1, whereas disopyramide, lignocaine, propafenone, metoprolol, dl-sotalol, and verapamil have no inhibitory effect.
Topics: Amiodarone; Anti-Arrhythmia Agents; Binding, Competitive; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Metoprolol; Propafenone; Receptors, Thyroid Hormone; Sotalol; Triiodothyronine; Verapamil | 1995 |
Antiarrhythmic effects of bisaramil on triggered arrhythmias produced by intracoronary injection of digitalis and adrenaline in the dog.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Chlorobenzenes; Digitalis Glycosides; Disease Models, Animal; Disopyramide; Dogs; Epinephrine; Female; Flecainide; Injections, Intra-Arterial; Lidocaine; Male; Ouabain; Verapamil | 1995 |
Effects of E-4031 on atrial fibrillation threshold in guinea pig atria: comparative study with class I antiarrhythmic drugs.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Disopyramide; Electric Stimulation; Female; Flecainide; Guinea Pigs; Heart Atria; Heart Conduction System; In Vitro Techniques; Lidocaine; Male; Piperidines; Procainamide; Pyridines; Refractory Period, Electrophysiological | 1994 |
Complex frequency-dependent interaction of class-I antiarrhythmic drugs as they affect intraventricular conduction.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Cardiac Pacing, Artificial; Disopyramide; Drug Combinations; Electrocardiography; Female; Heart Conduction System; Humans; Lidocaine; Male; Middle Aged; Ventricular Function | 1995 |
Frequency dependent effects of class I antiarrhythmic agents studied in patients with implanted pacemakers.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cross-Over Studies; Disopyramide; Electrocardiography; Flecainide; Humans; Lidocaine; Pacemaker, Artificial | 1994 |
Clinical evaluation of the use-dependent QRS prolongation and the reverse use-dependent QT prolongation of class I and class III antiarrhythmic agents and their value in predicting efficacy.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Piperidines; Potassium Channels; Pyridines; Sodium Channels | 1993 |
Effects of pilsicainide on the atrial fibrillation threshold in guinea pig atria. A comparative study with disopyramide, lidocaine and flecainide.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Electrophysiology; Female; Flecainide; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Male | 1993 |
Antiarrhythmic agents act differently on the activation phase of the ACh-response in guinea-pig atrial myocytes.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Electric Conductivity; Flecainide; Guinea Pigs; Lidocaine; Male; Myocardium; Potassium; Potassium Channels; Propafenone | 1993 |
Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Procainamide; Syndrome; Tachycardia, Ventricular; Verapamil | 1996 |
Binding of disopyramide, methadone, dipyridamole, chlorpromazine, lignocaine and progesterone to the two main genetic variants of human alpha 1-acid glycoprotein: evidence for drug-binding differences between the variants and for the presence of two separ
Topics: Binding, Competitive; Carrier Proteins; Chlorpromazine; Dipyridamole; Disopyramide; Genetic Variation; Humans; Lidocaine; Ligands; Methadone; Orosomucoid; Pharmaceutical Preparations; Progesterone | 1996 |
Effects of blockade of fast and slow inward current channels on ventricular fibrillation in the pig heart.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Flecainide; Lidocaine; Mexiletine; Models, Biological; Sodium-Potassium-Exchanging ATPase; Swine; Ventricular Fibrillation; Verapamil | 1996 |
Ischaemia-induced loss or reversal of the effects of the class I antiarrhythmic drugs on vulnerability to fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Vessels; Disopyramide; Electric Stimulation; Electrophysiology; Female; Flecainide; Heart Conduction System; In Vitro Techniques; Injections, Intravenous; Lidocaine; Male; Myocardial Ischemia; Swine; Ventricular Fibrillation | 1997 |
Electrophysiologic effects of sodium channel blockade on anisotropic conduction and conduction block in canine myocardium: preferential slowing of longitudinal conduction by flecainide versus disopyramide or lidocaine.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Dogs; Electric Conductivity; Electrophysiology; Flecainide; Heart Conduction System; Heart Ventricles; Lidocaine; Sodium Channels; Ventricular Fibrillation | 1997 |
Amiodarone inhibits production of tumor necrosis factor-alpha by human mononuclear cells: a possible mechanism for its effect in heart failure.
Topics: Amiodarone; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Heart Failure; Humans; Interleukin-1; Interleukin-6; Lidocaine; Monocytes; Osmolar Concentration; Quinidine; Tumor Necrosis Factor-alpha | 1997 |
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle.
Topics: Animals; Anti-Arrhythmia Agents; Aorta; Desipramine; Disopyramide; Flecainide; Imipramine; In Vitro Techniques; Lidocaine; Male; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Quinidine; Rats; Rats, Sprague-Dawley | 1997 |
The rise time of the monophasic action potential--a new index of local use-dependent conductivity by sodium channel blockers in human myocardium.
Topics: Action Potentials; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Disopyramide; Female; Heart; Heart Conduction System; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Sodium Channel Blockers; Sodium Channels | 1997 |
Percutaneous absorption of disopyramide, lidocaine and trimecaine.
Topics: Animals; Anti-Arrhythmia Agents; Cyclohexenes; Disopyramide; Lidocaine; Limonene; Male; Rats; Rats, Wistar; Skin Absorption; Solvents; Terpenes; Trimecaine | 1998 |
Decrease in the high frequency QRS components depending on the local conduction delay.
Topics: Animals; Disopyramide; Dogs; Electrocardiography; Flecainide; Fourier Analysis; Heart Conduction System; Lidocaine; Sodium Channel Blockers; Time | 1998 |
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyramide; Dogs; Electrocardiography; Flecainide; Injections; Lidocaine; Piperidines; Pyridines; Sodium Channels; Ventricular Fibrillation; Verapamil | 1999 |
Effects of antiarrhythmic drugs on the monophasic action potential of the canine isolated, blood-perfused ventricular septum preparation.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Heart Septum; In Vitro Techniques; Lidocaine; Male; Tetrodotoxin; Verapamil | 1998 |
Transient appearance of antegrade conduction via an AV accessory pathway caused by atrial fibrillation in a patient with intermittent Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Electrocardiography; Heart Conduction System; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Procainamide; Wolff-Parkinson-White Syndrome | 2000 |
[Antiarrhythmic effects of pilsicainide hydrochloride and effects on cardiac function and ECG in dogs: comparison with disopyramide].
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, Animal; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Hemodynamics; Infusions, Intravenous; Lidocaine; Ligation | 2000 |
Direct effects of class I antiarrhythmic drugs on epicardial electrograms in dogs.
Topics: Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Electrocardiography; Flecainide; Lidocaine; Pericardium | 1999 |
Anisotropic effects of sodium channel blockers on the wavelength for ventricular excitation in dogs.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Dogs; Electrocardiography; Electrophysiology; Flecainide; Heart Conduction System; Heart Ventricles; Lidocaine; Sodium Channel Blockers; Sodium Channels; Tachycardia, Ventricular; Ventricular Fibrillation; Ventricular Function | 2000 |
QT-prolonging class I drug, disopyramide, does not aggravate but suppresses adrenaline-induced arrhythmias. Comparison with cibenzoline and pilsicainide.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Disopyramide; Dogs; Drug Interactions; Electrocardiography; Epinephrine; Female; Heart Rate; Imidazoles; Lidocaine; Male | 2000 |
Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells.
Topics: Amino Acid Substitution; Anti-Arrhythmia Agents; Cell Line; Cloning, Molecular; Disopyramide; Flecainide; Heart; Humans; Lidocaine; Membrane Potentials; Models, Biological; Myocardium; Recombinant Proteins; Sodium Channel Blockers; Sodium Channels; Transfection | 2000 |
Atrial fibrillation threshold predicted long-term efficacy of pharmacological treatment of patients without structural heart disease.
Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Disopyramide; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Treatment Outcome | 2002 |
Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Biological Transport; Cell Line; Disopyramide; Dose-Response Relationship, Drug; Histamine; Humans; Lidocaine; Mice; Organic Cation Transport Proteins; Phenytoin; Procainamide; Quinidine | 2004 |
Pilsicainide in breast milk from a mother: comparison with disopyramide and propafenone.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Disopyramide; Female; Humans; Lidocaine; Milk, Human; Propafenone | 2005 |
Heart rate variability is a useful parameter for evaluation of anticholinergic effect associated with inducibility of atrial fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cholinergic Antagonists; Disopyramide; Dogs; Electrocardiography; Heart Atria; Heart Conduction System; Heart Rate; Lidocaine; Treatment Outcome | 2005 |
Comparison of acute reduction in left ventricular outflow tract pressure gradient in obstructive hypertrophic cardiomyopathy by disopyramide versus pilsicainide versus cibenzoline.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography, Doppler; Female; Humans; Imidazoles; Lidocaine; Linear Models; Male; Middle Aged; Propranolol; Prospective Studies; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Pressure; Verapamil | 2010 |