lidocaine and desipramine

lidocaine has been researched along with desipramine in 60 studies

Research

Studies (60)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (30.00)	18.7374
1990's	5 (8.33)	18.2507
2000's	23 (38.33)	29.6817
2010's	14 (23.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Chiang, GH; Unger, SH	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Caron, G; Ermondi, G	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Sen, S; Sinha, N	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kelder, D; Ross, SB	2
Sieber-Blum, M	1
Daugherty, A; Frayn, KN; Redfern, WS; Woodward, B	1
Brock, JA; Cunnane, TC	1
Abrahamsson, T; Carlsson, L	1
Paton, DM	3
Day, MD; Owen, DA; Warren, PR	1
Westfall, DP	1
Treitman, P	1
Cosmides, GJ	1
Astrom, A; Evers, H; Goldman, V	1
Andersson, A; Olsson, S; Tjälve, H	1
Carpenter, P; Gobel, FL; Hulsing, DJ	1
Chen, NH; Reith, ME	1
Arimoto, H; Fujii, T; Kurihara, Y; Mitsutsuka, Y	1
Bayer, BM; Berkeley, MB; Daussin, S; Hernandez, MC	1
Bernards, CM	1
Fernández del Pozo, B; Fernández, C; Pérez-Vizcaíno, F; Tamargo, J; Zaragozá, F	1
Shannon, HE; Womer, DE	1
Arai, S; Dohi, T; Kihira, K; Kitayama, S; Kumagai, K; Kumagai, M; Morita, K	1
Swant, J; Thompson, AM; Wagner, JJ	1
Dohi, T; Kitayama, T; Morioka, N; Morita, K; Song, L	1
Beth Kotok, M; Dworkin, RH; Foster, DC; Howard, FM; Huang, LS; Oakes, D; Stodgell, CJ; Watts, A	1
Kile, BM; Park, J; Wightman, RM	1
Dworkin, RH; Foster, DC; Howard, FM; Huang, LS; Kotok, MB; Oakes, D; Poleshuck, EL; Stodgell, CJ; Watts, A	1
Bornstein, J; Bueno-Notivol, J; Hernandez, AV; Pérez-López, FR; Preti, M; Vieira-Baptista, P	1

Reviews

2 review(s) available for lidocaine and desipramine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Systematic review and meta-analysis of the effects of treatment modalities for vestibulodynia in women. The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 2019, Volume: 24, Issue:5 Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Desipramine; Dyspareunia; Estrogens; Female; Humans; Laser Therapy; Lidocaine; Network Meta-Analysis; Pain Measurement; Randomized Controlled Trials as Topic; Sexual Behavior; Transcranial Direct Current Stimulation; Treatment Outcome; Vaginal Creams, Foams, and Jellies; Vulvodynia	2019

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Systematic review and meta-analysis of the effects of treatment modalities for vestibulodynia in women.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 2019, Volume: 24, Issue:5

Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Desipramine; Dyspareunia; Estrogens; Female; Humans; Laser Therapy; Lidocaine; Network Meta-Analysis; Pain Measurement; Randomized Controlled Trials as Topic; Sexual Behavior; Transcranial Direct Current Stimulation; Treatment Outcome; Vaginal Creams, Foams, and Jellies; Vulvodynia

2019

Trials

2 trial(s) available for lidocaine and desipramine

Article	Year
The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness. Obstetrics and gynecology, 2009, Volume: 113, Issue:4 Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, Obstetrical and Gynecological; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Humans; Lidocaine; Pain; Pain Measurement; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Vulvar Diseases	2009
Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial. Obstetrics and gynecology, 2010, Volume: 116, Issue:3 Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Antidepressive Agents, Tricyclic; Desipramine; Double-Blind Method; Female; Humans; Lidocaine; Treatment Outcome; Vulvodynia; Young Adult	2010

Article

Year

The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.

Obstetrics and gynecology, 2009, Volume: 113, Issue:4

Topics: Adrenergic Uptake Inhibitors; Adult; Anesthetics, Local; Coitus; Desipramine; Diagnostic Techniques, Obstetrical and Gynecological; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Humans; Lidocaine; Pain; Pain Measurement; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Vulvar Diseases

2009

Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial.

Obstetrics and gynecology, 2010, Volume: 116, Issue:3

Topics: Administration, Intravaginal; Administration, Oral; Adult; Anesthetics, Local; Antidepressive Agents, Tricyclic; Desipramine; Double-Blind Method; Female; Humans; Lidocaine; Treatment Outcome; Vulvodynia; Young Adult

2010

Other Studies

56 other study(ies) available for lidocaine and desipramine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity. Journal of medicinal chemistry, 1981, Volume: 24, Issue:3 Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship	1981
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Active transport of 3H-bretylium in the rat vas deferens in vitro. Acta physiologica Scandinavica, 1976, Volume: 97, Issue:2 Topics: Aminobenzoates; Amphetamine; Anesthetics, Local; Animals; Biological Transport, Active; Bretylium Compounds; Chlorides; Cocaine; Desipramine; Hydroxybenzoate Ethers; Hydroxydopamines; Imipramine; Lidocaine; Male; meta-Aminobenzoates; Ouabain; Rats; Reserpine; Sodium; Sympathetic Nervous System; Temperature; Vas Deferens	1976
Effect of veratridine on the fluxes of 3H-noradrenaline and 3h-bretylium in the rat vas deferens in vitro. Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 295, Issue:3 Topics: Aminobenzoates; Anesthetics, Local; Animals; Bretylium Compounds; Calcium; Desipramine; In Vitro Techniques; Lidocaine; Male; Muscle, Smooth; Norepinephrine; Rats; Reserpine; Tetrodotoxin; Vas Deferens; Veratridine; Veratrine	1976
Inhibition of the adrenergic phenotype in cultured neural crest cells by norepinephrine uptake inhibitors. Developmental biology, 1989, Volume: 136, Issue:2 Topics: Adrenergic Fibers; Animals; Biological Transport; Chlorpromazine; Citalopram; Coturnix; Desipramine; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; In Vitro Techniques; Lidocaine; Mazindol; Neural Crest; Neurotransmitter Uptake Inhibitors; Norepinephrine; Tyrosine 3-Monooxygenase	1989
The role of catecholamines in the production of ischaemia-induced ventricular arrhythmias in the rat in vivo and in vitro. British journal of pharmacology, 1986, Volume: 87, Issue:1 Topics: Adrenal Medulla; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Arrhythmias, Cardiac; Catecholamines; Coronary Disease; Desipramine; In Vitro Techniques; Lidocaine; Male; Myocardium; Norepinephrine; Normetanephrine; Quinidine; Rats; Rats, Inbred Strains; Reserpine; Sympathectomy, Chemical; Tritium	1986
Studies on the mode of action of bretylium and guanethidine in post-ganglionic sympathetic nerve fibres. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:5 Topics: Amphetamine; Animals; Autonomic Fibers, Postganglionic; Bretylium Compounds; Bretylium Tosylate; Desipramine; Electrophysiology; Guanethidine; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Tetrodotoxin; Vas Deferens	1988
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2 Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; Clonidine; Coronary Disease; Desipramine; Fluoxetine; Heart; Isomerism; Lidocaine; Male; Maprotiline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains	1988
Evidence for carrier-mediated efflux of noradrenaline from the axoplasm of adrenergic nerves in rabbit atria. The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:3 Topics: Animals; Axons; Cell Membrane; Cocaine; Desipramine; Heart Atria; In Vitro Techniques; Isoproterenol; Lidocaine; Metaraminol; Norepinephrine; Normetanephrine; Rabbits; Reserpine; Sympathetic Nervous System; Time Factors; Tritium; Tyramine	1973
An adrenergic neuron blocking action of propranolol in isolated tissues. The Journal of pharmacy and pharmacology, 1968, Volume: 20 Topics: Amphetamine; Animals; Arteries; Desipramine; Ear; Guanethidine; Ileum; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Propranolol; Rabbits; Rats; Vas Deferens	1968
Antagonism by protriptyline and desipramine of the response of the vas deferens of the rat to norepinephrine, acetylcholine and potassium. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:3 Topics: Acetylcholine; Animals; Cocaine; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Inflammation; Lidocaine; Male; Norepinephrine; Potassium; Propylamines; Rats; Vas Deferens	1973
Mechanism of efflux of noradrenaline from adrenergic nerves in rabbit atria. British journal of pharmacology, 1973, Volume: 49, Issue:4 Topics: Animals; Cocaine; Desipramine; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Male; Metaraminol; Norepinephrine; Normetanephrine; Pargyline; Potassium; Premedication; Rabbits; Reserpine; Sodium; Sympathetic Nervous System; Temperature; Time Factors; Tritium; Tyramine	1973
Desipramine poisoning. JAMA, 1972, May-08, Volume: 220, Issue:6 Topics: Desipramine; Diazepam; Gastric Lavage; Humans; Infant; Lidocaine; Male; Paraldehyde; Poisoning; Potassium Chloride; Respiration, Artificial	1972
Pharmacology-toxicology. Science (New York, N.Y.), 1970, May-22, Volume: 168, Issue:3934 Topics: Antidepressive Agents; Blood Pressure; Brain; Contraceptives, Oral; Cytochromes; Desipramine; Diazepam; Endoplasmic Reticulum; Histamine; Lidocaine; Liver; Methylphenidate; Methyltyrosines; National Institutes of Health (U.S.); Norepinephrine; Norethindrone; Nortriptyline; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Placenta; Progesterone; Smoking; United States	1970
The effect of tricyclic antidepressant on the cardiovascular effects of local anaesthetic solutions containing different vasoconstrictors. Anaesthesia, 1971, Volume: 26, Issue:1 Topics: Animals; Blood Pressure; Desipramine; Dogs; Drug Synergism; Epinephrine; Felypressin; Heart Rate; Lidocaine; Norepinephrine; Prilocaine; Vasoconstrictor Agents; Vasopressins	1971
The uptake of 14C-chloroquine by mouse pancreatic islets in vitro. Acta pharmacologica et toxicologica, 1980, Volume: 47, Issue:1 Topics: Absorption; Animals; Chloroquine; Chlorpromazine; Desipramine; Glucose; Hydrogen-Ion Concentration; Imipramine; Islets of Langerhans; Lidocaine; Mice; Nicotine; Nitrogen; Ouabain; Quinacrine; Temperature	1980
Desipramine cardiac toxicity. Minnesota medicine, 1982, Volume: 65, Issue:4 Topics: Adult; Bretylium Tosylate; Depressive Disorder; Desipramine; Heart Ventricles; Humans; Hypotension; Lidocaine; Male; Tachycardia	1982
Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships. Journal of neurochemistry, 1994, Volume: 63, Issue:5 Topics: Animals; Biogenic Monoamines; Citalopram; Cocaine; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Lidocaine; Ligands; Male; Microdialysis; Movement; Norepinephrine; Piperazines; Rats; Serotonin; Tetrodotoxin; Ventral Tegmental Area	1994
Surface ionization organic mass spectrometry of imipramine, desipramine, clomipramine, and lidocaine. Analytical chemistry, 1994, Jun-01, Volume: 66, Issue:11 Topics: Clomipramine; Desipramine; Humans; Imipramine; Lidocaine; Mass Spectrometry; Sensitivity and Specificity; Surface Properties	1994
In vitro effects of cocaine, lidocaine and monoamine uptake inhibitors on lymphocyte proliferative responses. Immunopharmacology and immunotoxicology, 1994, Volume: 16, Issue:2 Topics: Animals; B-Lymphocytes; Cells, Cultured; Cocaine; Desipramine; Fluoxetine; Lidocaine; Lymphocyte Activation; Male; Mitogens; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes	1994
Centrally mediated hemodynamic effects of cocaine in rabbits: the role of local anesthetic actions and biogenic amine re-uptake blockage. European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1 Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Biogenic Monoamines; Blood Pressure; Central Nervous System; Cocaine; Desipramine; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intraventricular; Lidocaine; Male; Neurotransmitter Uptake Inhibitors; Rabbits	1996
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle. General pharmacology, 1997, Volume: 29, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Aorta; Desipramine; Disopyramide; Flecainide; Imipramine; In Vitro Techniques; Lidocaine; Male; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Quinidine; Rats; Rats, Sprague-Dawley	1997
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice. Neuropharmacology, 2000, Jul-24, Volume: 39, Issue:10 Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fentanyl; Lidocaine; Male; Mice; Morphine; Oxymetazoline; Pain; Pain Measurement; Pertussis Toxin; Temperature; Virulence Factors, Bordetella	2000
Effect of veratrine alkaloids on the efflux of extra-granular noradrenaline from rabbit atria. Journal of neurochemistry, 1976, Volume: 27, Issue:5 Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Arrhythmia Agents; Biological Transport; Catechol O-Methyltransferase Inhibitors; Cocaine; Colchicine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Atria; In Vitro Techniques; Lidocaine; Male; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Rabbits; Reserpine; Tetrodotoxin; Veratrine	1976
Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics. Brain research, 2003, Feb-21, Volume: 964, Issue:1 Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Brain; Brain Chemistry; Citalopram; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Lidocaine; Male; Maprotiline; Mice; Mice, Inbred ICR; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Seizures; Selective Serotonin Reuptake Inhibitors; Symporters; Time Factors	2003
Cocaine-induced modulation of long-term potentiation in the CA1 region of rat hippocampus. Neuropharmacology, 2005, Volume: 49, Issue:2 Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Benzazepines; Cocaine; Desipramine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Lidocaine; Long-Term Potentiation; Neurotransmitter Uptake Inhibitors; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Salicylamides; Tetrodotoxin	2005
Down-regulation of norepinephrine transporter function induced by chronic administration of desipramine linking to the alteration of sensitivity of local-anesthetics-induced convulsions and the counteraction by co-administration with local anesthetics. Brain research, 2006, Jun-22, Volume: 1096, Issue:1 Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Desipramine; Down-Regulation; Drug Interactions; Lidocaine; Male; Mice; Mice, Inbred ICR; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Seizures; Sodium Channel Blockers	2006
In vivo voltammetric monitoring of norepinephrine release in the rat ventral bed nucleus of the stria terminalis and anteroventral thalamic nucleus. The European journal of neuroscience, 2009, Dec-03, Volume: 30, Issue:11 Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Anterior Thalamic Nuclei; Chromatography, High Pressure Liquid; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Electric Stimulation; Electrochemical Techniques; Lidocaine; Male; Microelectrodes; Neural Pathways; Norepinephrine; Piperazines; Raclopride; Rats; Rats, Sprague-Dawley; Septal Nuclei; Tissue Distribution; Yohimbine	2009