lidocaine and cyclosporine

lidocaine has been researched along with cyclosporine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (37.04)18.2507
2000's9 (33.33)29.6817
2010's8 (29.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Elkamhawy, A; Hassan, AHE; Lee, J; Moon, B; Pae, AN; Park, BG; Park, HM; Park, JE; Ra, H; Roh, EJ1
Hunt, CM; Stave, GM; Westerkam, WR1
Cakaloglu, Y; Devlin, J; Tredger, JM; Williams, R1
Armstrong, VW; Kaltefleiter, M; Loss, M; Luy-Kaltefleiter, M; Oellerich, M; Ringe, B; Schütz, E; Wieland, E; Winkler, M1
Beyrau, R; Christians, U; Esselmann, H; Kaltefleiter, M; Kohlhaw, K; Linck, A; Luy, M; Oellerich, M; Ringe, B; Sürig, T1
Bevilacqua, G; Campanella, PG; Collecchi, P; Della Capanna, S; Di Stefano, R; Mosca, F; Pietrabissa, A; Scarcello, E; Turini, L1
Davis, A; Krafchik, BR1
Adam, R; Azoulay, D; Beaune, P; Bismuth, H; Dolizy, I; Fredj, G; Gries, JM; Lemoine, A1
Floreani, AA; Rennard, SI1
Adam, R; Azoulay, D; Bismuth, H; Davoll, S; Debuire, B; Lemoine, A; Pham, P; Salvucci, M1
Deykin, A; Israel, E1
Chieregato, C; D'Onghia, FS; Miccolis, D; Rosina, P1
Kamiya, Y; Kaneko, Y; Ohta, K1
Beaugerie, L; Cosnes, J; Daniel, F; Marteau, P; Seksik, P1

Reviews

5 review(s) available for lidocaine and cyclosporine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New drugs in pediatric dermatology.
    Current opinion in pediatrics, 1993, Volume: 5, Issue:2

    Topics: Acyclovir; Anesthetics, Local; Calcitriol; Child; Cyclosporine; Dermatologic Agents; Drug Combinations; Humans; Interferon alpha-2; Interferon-alpha; Lidocaine; Lidocaine, Prilocaine Drug Combination; Prilocaine; Recombinant Proteins; Skin Diseases

1993
Experimental treatments for asthma.
    Current opinion in pulmonary medicine, 1997, Volume: 3, Issue:1

    Topics: Administration, Inhalation; Anti-Inflammatory Agents; Antirheumatic Agents; Asthma; Auranofin; Bradykinin; Cholinergic Antagonists; Chymases; Cyclosporine; Diuretics; Drugs, Investigational; Genetic Therapy; Heparin Antagonists; Humans; Immunosuppressive Agents; Kinins; Leukotriene Antagonists; Lidocaine; Muscarinic Antagonists; Neurokinin A; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Receptors, Tachykinin; Serine Endopeptidases; T-Lymphocytes; Tryptases

1997
Newer therapeutic agents for asthma.
    Disease-a-month : DM, 1999, Volume: 45, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Bronchodilator Agents; Cyclosporine; Fluticasone; Forced Expiratory Volume; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Indoles; Leukotriene Antagonists; Lidocaine; Methotrexate; Phenylcarbamates; Salmeterol Xinafoate; Sulfonamides; Tosyl Compounds; Treatment Outcome

1999
[Refractory proctitis].
    Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:4

    Topics: Administration, Oral; Adrenal Cortex Hormones; Algorithms; Anesthetics, Local; Antibodies, Monoclonal; Aspirin; Azathioprine; Biopsy; Cyclosporine; Drug Therapy, Combination; Escherichia coli; Forecasting; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Lidocaine; Methotrexate; Nicotine; Patient Compliance; Probiotics; Proctitis; Randomized Controlled Trials as Topic; Rectum; Suppositories; Time Factors

2007

Trials

3 trial(s) available for lidocaine and cyclosporine

ArticleYear
Metabolic liver function and lipoprotein metabolism after orthotopic liver transplantation in patients on immunosuppressive therapy with FK 506 or cyclosporine.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Antilymphocyte Serum; Apolipoprotein A-I; Apolipoproteins B; Azathioprine; Bilirubin; Cholesterol; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Europe; Humans; Lidocaine; Liver Function Tests; Liver Transplantation; Methylprednisolone; Middle Aged; Prednisolone; Tacrolimus; Time Factors

1995
The yin and yang of lidocaine and cyclosporine metabolism in liver graft recipients.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Cyclosporine; Drug Interactions; Humans; Lidocaine; Liver Transplantation; Metabolic Clearance Rate; Microsomes, Liver; Models, Theoretical; NADP; Prospective Studies

1994
Acute cyclosporine toxicity after liver transplantation is predicted by the lidocaine monoethylglycinexylidide test in the donor.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1997, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Cyclosporine; Female; Humans; Kidney Diseases; Lidocaine; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Nervous System Diseases; Prognosis; Prospective Studies; Tissue Donors

1997

Other Studies

19 other study(ies) available for lidocaine and cyclosporine

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.
    European journal of medicinal chemistry, 2017, Mar-10, Volume: 128

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Drug Discovery; Hippocampus; Immunosuppressive Agents; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Molecular Docking Simulation; Neurons; Piperazines; Protein Conformation; Urea

2017
Effect of age and gender on the activity of human hepatic CYP3A.
    Biochemical pharmacology, 1992, Jul-22, Volume: 44, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Body Weight; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diltiazem; Humans; Lidocaine; Microsomes, Liver; Middle Aged; Nifedipine; Oxidoreductases, N-Demethylating; Quinidine; Sex Factors; Smoking

1992
Importance of cytochrome P-450IIIA activity in determining dosage and blood levels of FK 506 and cyclosporine in liver transplant recipients.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Breath Tests; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Erythromycin; Female; Humans; Lidocaine; Liver Transplantation; Male; Oxidoreductases, N-Demethylating; Predictive Value of Tests; Regression Analysis; Tacrolimus

1994
Effect of cyclosporine-A pretreatment on lidocaine metabolite formation in the regenerating rat liver.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Animals; Cyclosporine; Hepatectomy; Lidocaine; Liver; Liver Regeneration; Male; Organ Size; Rats; Rats, Inbred Lew; Reference Values

1994
Lidocaine metabolite formation in the liver donor as a predictive test for the safe and efficient introduction of cyclosporine in the recipient.
    Transplantation proceedings, 1993, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Brain Death; Child; Cyclosporine; Cytochrome P-450 Enzyme System; Female; Humans; Isoenzymes; Lidocaine; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Prognosis; Tissue Donors

1993
Psoriasis and side-effects of mesotherapy.
    International journal of dermatology, 2001, Volume: 40, Issue:9

    Topics: Aged; Aminophylline; Anesthetics, Local; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Injections, Intradermal; Lidocaine; Psoriasis; Sciatica; Vasodilator Agents; Xanthinol Niacinate

2001
Lidocaine-induced apoptosis and necrosis in U937 cells depending on its dosage.
    Biomedical research (Tokyo, Japan), 2005, Volume: 26, Issue:6

    Topics: Anesthetics, Local; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cyclosporine; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lidocaine; Membrane Potentials; Mitochondria; Necrosis; Tetrazolium Salts; U937 Cells

2005