Compounds > lidocaine

lidocaine and coumarin

lidocaine has been researched along with coumarin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's5 (50.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Jolivette, LJ; Ward, KW1
Jolivette, LJ; Nagilla, R; Ward, KW1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Arvela, P; Bäckstrom, M; Pelkonen, O; Rautio, A; Sotaniemi, EA1
Arvela, P; Mustajoki, P; Mustajoki, S; Pelkonen, O; Rautio, A1
Groothuis, GM; Merema, MT; van Midwoud, PM; Verpoorte, E1

Other Studies

10 other study(ies) available for lidocaine and coumarin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Capsules; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Epilepsy; Female; Humans; Injections, Intravenous; Isoenzymes; Kidney Diseases; Kidney Function Tests; Lidocaine; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Middle Aged; Mixed Function Oxygenases; Peptide Fragments; Procollagen; Umbelliferones

1995
Effects of heme arginate on cytochrome P450-mediated metabolism of drugs in patients with variegate porphyria and in healthy men.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:1

    Topics: Adult; Arginine; Caffeine; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Heme; Humans; Isoenzymes; Lidocaine; Male; Middle Aged; Porphyrias, Hepatic; Reference Values

1994
A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices.
    Lab on a chip, 2010, Oct-21, Volume: 10, Issue:20

    Topics: Animals; Coumarins; Equipment Design; Equipment Failure Analysis; Flow Injection Analysis; Intestinal Mucosa; Lidocaine; Liver; Male; Microfluidic Analytical Techniques; Organ Culture Techniques; Rats; Rats, Wistar

2010