lidocaine has been researched along with clonidine in 134 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (5.97) | 18.7374 |
| 1990's | 36 (26.87) | 18.2507 |
| 2000's | 58 (43.28) | 29.6817 |
| 2010's | 29 (21.64) | 24.3611 |
| 2020's | 3 (2.24) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Blake, DE; Holsapple, MP; Yim, GK | 1 |
| Tuleutaev, MD | 1 |
| Boico, O; Bonnet, F; Mazoit, JX | 1 |
| Brunet, PC; Gaumann, DM; Jirounek, P | 2 |
| Dai, M; Goyagi, T; Kimura, T; Naito, H; Nishikawa, T | 1 |
| Della Santa, D; Forster, A; Gaumann, D; Griessen, M; Habre, W; Poinsot, O | 1 |
| Thomas, GP; Varma, RK | 1 |
| Asakura, N; Hamaya, Y; Harukuni, I; Nishikawa, T | 1 |
| Brighouse, D; Glynn, CJ; O'Connor, M | 1 |
| Dohi, S; Nishikawa, T | 1 |
| Cousins, MJ; Tanelian, DL | 1 |
| Benhamou, D; Labaille, T; Veillette, Y | 1 |
| Ang, ET; Debaene, B; Galet, C; Goldfarb, G; Jolis, P; Khon, S | 1 |
| Ben-Zvi, Z; Garty, M; Hurwitz, A | 1 |
| Chen, CH; Tzeng, JI; Wang, JJ | 1 |
| Abrahamsson, T; Carlsson, L | 1 |
| Day, MD; Roach, AG | 1 |
| Blakemore, C; Larkman, A; Nicoll, A | 1 |
| Bainton, BG; Carpenter, RL; Chiu, AA; Gerancher, JC; Liu, S; Neal, JM | 1 |
| Ishii, A; Karasawa, A; Kishibayashi, N; Tomaru, A | 1 |
| Namba, H; Namiki, A; Tanaka, S; Tsuchida, H | 1 |
| Bardin, M; Chantelauze, C; Courteix, C; Eschalier, A; Lavarenne, J | 1 |
| Hämäläinen, MM; Pertovaara, A | 1 |
| De Kock, M; Lavandhomme, P; Scholtes, JL | 1 |
| Goto, H; Hirakawa, M; Yokoyama, M | 1 |
| Munro, HM; Paxton, LD; Sleigh, JW | 1 |
| Alvarez, ML; Baños, G; Figueira, A; Guerra, V; Núñez, M; Rodríguez, M | 1 |
| Glynn, C; O'Sullivan, K | 1 |
| Lemos, D; Muller, A | 1 |
| Bailey, PL; Reinhart, DJ; Stagg, KS; Walker, EB; Walker, KG; Wang, W; Zaugg, SE | 1 |
| Benhamou, D; Mazoit, JX; Samii, K; Veillette, Y | 1 |
| Bernard, JM; Macaire, P | 1 |
| Iwasaki, H; Kawamata, M; Kawamata, T; Namiki, A; Omote, K | 1 |
| Horikawa, Y; Kagawa, T; Kondo, M; Obara, H; Ohnishi, H | 1 |
| Franssen, M; Goff, JR; Janni, G; Jasmin, L; Kohan, L | 1 |
| Dohi, S; Iida, H; Ohata, H; Watanabe, Y | 1 |
| Benrhaiem, M; Favereau, JP; Grouille, D; Ledan, C; Orsel, I | 1 |
| Abderrahim, N; Atyaoui, F; Cherif, A; Daghfous, M; Daoud, A; Ghazouani, S; Nafaa, N; Najah, N | 1 |
| Altenburg, SP; Farah, MB | 1 |
| Dobrydnjov, I; Samarütel, J | 1 |
| Bernard, JM; Bonnet, F; Gentili, M | 1 |
| Klatt, JL; Klatt, ML; Reuben, SS; Steinberg, RB | 1 |
| Gintautas, J; Housny, W; Kraynack, BJ | 1 |
| Shannon, HE; Womer, DE | 1 |
| Atanassoff, PG; Castro Bande, M | 1 |
| Hao, S; Iwasaki, H; Takahata, O | 1 |
| Abbassi, O; al Harrar, R; Bouaggad, A; Bouderka, MA; Samkaoui, MA | 1 |
| Andersen, JB; Grey, MJ; Ladouceur, M; Nielsen, JB; Sinkjaer, T | 1 |
| Baba, Y; Inomata, S; Kakiuchi, Y; Kohda, Y; Miyabe, M; Nagashima, A; Nakayama, S; Okuyama, K; Tanaka, E; Toyooka, H; Yamasaki, Y | 1 |
| Bharti, N; Kaul, HL; Khokhar, SK; Madan, R; Shende, D | 1 |
| Bernards, CM; Kopacz, DJ | 1 |
| Eberhart, LH; Kranke, P; Roewer, N; Tramèr, MR | 1 |
| Bharti, N; Kaul, HL; Khokhar, SK; Madan, R; Mishra, S | 1 |
| Brasseur, G; Calenda, E; Quintyn, JC | 1 |
| Cousins, MJ; McClelland, JM; Parisod, E; Siddall, PJ; Viney, M | 1 |
| Asada, A; Ikeda, Y; Mori, T; Nishikawa, K; Ohashi, K | 1 |
| Baraka, A; Kanazi, GE; Rizk, L; Tran, SB | 1 |
| Inomata, S; Nagashima, A; Osaka, Y; Tanaka, E; Toyooka, H | 1 |
| Alayurt, S; Memis, D; Pamukcu, Z | 1 |
| Hendry, IA; Lacey, G; Morton, CR; Zhao, ZQ | 1 |
| Lönnqvist, PA; Naja, MZ; Ziade, MF | 1 |
| Ahmed, SU; Hord, ED; Vallejo, R | 2 |
| Bertelli, JA; Calixto, JB; Campos, MM; Ferreira, J; Rodrigues-Filho, R; Santos, AR | 1 |
| Beck, DR; Buvanendran, A; Kroin, JS; Topic, JE; Tuman, KJ; Watts, DE | 1 |
| Fang, L; Li, L; Liu, F; Sun, XX; Wang, TJ; Yang, LS | 1 |
| Faruqi, S; Kilaru, PA; Reuben, SS; Rosenthal, EA; Steinberg, RB | 1 |
| Bannova, IA; Bogdanova, LE; Mishunin, IuV; Morozov, IN; Nazarov, NA; Nikiforov, AV; Ostreĭkov, IF; Voĭkovskiĭ, OV | 1 |
| Adnan, T; Ayşe, K; Elif, AA; Gülnaz, A | 1 |
| Honda, K; Inomata, S; Misawa, S; Nagashima, A; Tanaka, E | 1 |
| Brkovic, B; Stojic, D; Todorovic, L | 1 |
| Frade, LP; Lauretti, GR; Lima, ICPR; Pereira, NL | 1 |
| Dixon, D; Faruqi, S; Madabhushi, L; Pristas, R; Reuben, SS; Wenner, S | 1 |
| Honda, K; Inomata, S; Nakamura, T; Tanaka, E | 1 |
| Bordes, M; Cros, AM | 1 |
| Almeida, RG; DeRossi, R; Frazílio, FO; Medeiros, U; Righetto, FR | 1 |
| Ball, AM; Smith, KM | 1 |
| Al-Tannir, MA; El-Rajab, M; Maaliki, H; Naja, MZ; Zeidan, A; Ziade, MF | 1 |
| Chen, LC; Huang, YS; Huh, BK; Wong, CS; Wu, CT; Yang, CP; Yeh, CC | 1 |
| Al-Tannir, MA; El-Rajab, M; Naja, ZM; Tawfik, OM; Ziade, FM | 2 |
| Goroszeniuk, T; Pratap, JN; Shankar, RK | 1 |
| Dohi, S; Iida, H; Oda, A; Osawa, Y; Tanahashi, S; Yamaguchi, S | 1 |
| Brkovic, B; Gardasevic, M; Jovic, N; Roganovic, J; Stojic, D; Todorovic, L | 1 |
| Higuchi, H; Kohjitani, A; Maeda, S; Miyawaki, T; Shimada, M; Yoshitomi, T | 1 |
| Bernard-Bertrand, F; Braque, S; Canciani, JP; Gentili, ME; Guezennec, D; Guillou, N | 1 |
| Hiruma, H; Kawakami, T; Shimizu, K; Sugie, H; Takenami, T | 1 |
| Chen, CL; Chen, JJ; Chiang, RP; Huang, CT; Lin, LH; Lue, JH; Tsai, YJ | 1 |
| Koshy, T; Misra, S; Suneel, PR | 1 |
| Brack, A; Keilig, S; Kranke, P; Schäfer, M | 1 |
| Klamt, JG; Nascimento, MS; Prado, WA | 1 |
| Byrne, D; Cofer, S; Goudy, S; Hersey, S; Labadie, R; Mantle, C; Moss, JR; Stowell, N; Swanson, E; Wang, L; Werkhaven, J | 1 |
| Kotsiou, A; Mourouzis, I; Saranteas, T; Tigka, E | 1 |
| Patel, N; Trivedi, V | 1 |
| Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T | 1 |
| Abi Nader, EL; Aouad, MT; Barakat, DE; Cherfane, GM; Hussein, JN; Karam, HS; Siddik-Sayyid, SM; Yazbeck-Karam, VG | 1 |
| Patil, PM; Patil, SP | 1 |
| Chon, JY; Moon, HS | 1 |
| Brown, K; Dohmeier, D; Hansen, K; Siebenaler, K; Zhang, Y | 1 |
| Abreu Baptista, JF; Brocco, MC; Cabral, SA; Carraretto, AR; Gomez, RS | 1 |
| Holland, MG; Marraffa, JM; Ryzewski, M; Sullivan, RW | 1 |
| Gurjeet, K; Rohan, B; Singh, PY | 1 |
| Esin, OR; Esin, RG; Sitnova, MA | 1 |
| Brkovic, B; Krsljak, E; Milic, MS; Stojic, D | 1 |
| Akhavan, A; Aminozarbian, MG; Davoudi, A; Mahdavian, P; Shadmehr, E | 1 |
| Chiba, K; Haraya, K; Kato, M; Sugiyama, Y | 1 |
| Agarwal, S; Dandriyal, R; Giri, KY; Pachauri, S; Prasad, NI; Rastogi, S; Singh, HP | 1 |
| Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S | 1 |
| Paisley, P; Serpell, M | 1 |
| Sivaramakrishnan, G; Sridharan, K | 1 |
| Ankouni, T; Mugharbil, A; Naja, AS; Naja, Z | 1 |
| Bedon-Carte, S; Bello, M; Leo, F; Oger, S; Ouattara, A; Vielstadte, C; Zaouter, C | 1 |
| Beck, M; Drum, M; Fowler, S; MacDonald, E; Nusstein, J; Reader, A | 1 |
| Al Assadi, S; Kanazi, G; Karam, C; Zeeni, C | 1 |
| Bengono Bengono, RS; Metogo, JM; Minkande, JZ; Ndikontar, R; Ngouatna, S; Ntock, FN; Tochie, JN | 1 |
8 review(s) available for lidocaine and clonidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Subarachnoid anesthesia: 100 years of an established technique].
Topics: Adrenergic alpha-Agonists; Adult; Ambulatory Surgical Procedures; Analgesics; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Child; Clonidine; Diffusion; Drug Synergism; Epinephrine; Female; Germany; Headache; History, 19th Century; History, 20th Century; Humans; Lidocaine; Male; Polyradiculopathy; Spain; Subarachnoid Space | 2000 |
Pharmacological treatment of postoperative shivering: a quantitative systematic review of randomized controlled trials.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Clonidine; Humans; Ketanserin; Lidocaine; Meperidine; Postoperative Complications; Randomized Controlled Trials as Topic; Shivering | 2002 |
[Inhalation induction with sevoflurane in paediatrics: what is new?].
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Drug Synergism; Electroencephalography; Humans; Infant; Intubation, Intratracheal; Lidocaine; Methyl Ethers; Morphine; Nitrous Oxide; Prospective Studies; Psychomotor Agitation; Seizures; Sevoflurane; Time Factors | 2006 |
Postoperative pain management: can transdermal patches help?
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Antiemetics; Clonidine; Fentanyl; Humans; Lidocaine; Nitric Oxide Donors; Nitroglycerin; Orthopedic Procedures; Pain, Postoperative; Postoperative Nausea and Vomiting; Scopolamine | 2006 |
Analgesia in the surgical intensive care unit.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities | 2017 |
The role of topiceuticals in cancer pain.
Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Capsaicin; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Humans; Lidocaine; Menthol; Neuralgia; Pain Management; Pain Measurement | 2017 |
Effect of clonidine on the efficacy of lignocaine local anesthesia in dentistry: A systematic review and meta-analysis of randomized, controlled trials.
Topics: Analgesics; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Clonidine; Drug Synergism; Humans; Lidocaine; Randomized Controlled Trials as Topic | 2018 |
45 trial(s) available for lidocaine and clonidine
| Article | Year |
|---|---|
Effects of epinephrine and clonidine on plasma concentrations of spinal bupivacaine.
Topics: Aged; Anesthesia, Spinal; Blood Pressure; Bupivacaine; Clonidine; Double-Blind Method; Epinephrine; Female; Heart Rate; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Neurons, Afferent; Time Factors | 1992 |
Oral clonidine preanaesthetic medication does not alter plasma lidocaine elimination during epidural anaesthesia in lightly anaesthetized patients.
Topics: Absorption; Administration, Oral; Adult; Anesthesia, Epidural; Clonidine; Female; Humans; Lidocaine; Middle Aged; Preanesthetic Medication | 1992 |
Comparison between clonidine and epinephrine admixture to lidocaine in brachial plexus block.
Topics: Adult; Anesthesia, Local; Brachial Plexus; Clonidine; Double-Blind Method; Epinephrine; Female; Humans; Lidocaine; Male; Nerve Block; Pain Measurement; Pain, Postoperative | 1992 |
[Effects of epidural clonidine added to lidocaine solution upon the requirements of sedatives during epidural anesthesia].
Topics: Adult; Anesthesia, Epidural; Clonidine; Diazepam; Female; Humans; Hysterectomy; Injections, Intravenous; Lidocaine; Middle Aged; Thiamylal | 1991 |
Clinical evaluation of clonidine added to lidocaine solution for epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Blood Pressure; Clonidine; Epinephrine; Female; Genital Diseases, Female; Heart Rate; Humans; Lidocaine; Middle Aged; Respiration | 1990 |
Oral clonidine prolongs lidocaine spinal anesthesia in human volunteers.
Topics: Administration, Oral; Anesthesia, Spinal; Clonidine; Cross-Over Studies; Double-Blind Method; Humans; Lidocaine; Preanesthetic Medication; Time Factors | 1995 |
Clonidine and lidocaine inhibition of isoflurane-induced tachycardia in humans.
Topics: Administration, Topical; Adult; Anesthesia, Inhalation; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Female; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Isoflurane; Lidocaine; Male; Norepinephrine; Preanesthetic Medication; Tachycardia | 1994 |
Intraoperative and postoperative analgesia using intravenous opioid, clonidine and lignocaine.
Topics: Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Clonidine; Colectomy; Double-Blind Method; Fentanyl; Humans; Injections, Intravenous; Intraoperative Care; Lidocaine; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Care; Time Factors | 1994 |
The cardiovascular response to ketamine: the effects of clonidine and lignocaine.
Topics: Adult; Aged; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Ketamine; Lidocaine; Male; Middle Aged; Surgical Procedures, Operative; Tachycardia | 1993 |
[Comparative study of clonidine and lidocaine on the attenuation of the intraocular pressure increase associated with laryngoscopy and endotracheal intubation].
Topics: Adult; Aged; Blood Pressure; Clonidine; Double-Blind Method; Female; Heart Rate; Humans; Intraocular Pressure; Intubation, Intratracheal; Laryngoscopy; Lidocaine; Male; Middle Aged; Ocular Hypertension; Preanesthetic Medication; Prospective Studies; Sympatholytics; Treatment Outcome | 1995 |
A double-blind randomised comparison of the effects of epidural clonidine, lignocaine and the combination of clonidine and lignocaine in patients with chronic pain.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Chronic Disease; Clonidine; Double-Blind Method; Drug Combinations; Female; Humans; Lidocaine; Male; Middle Aged; Pain | 1996 |
Postoperative analgesia after peripheral nerve block for podiatric surgery: clinical efficacy and chemical stability of lidocaine alone versus lidocaine plus clonidine.
Topics: Adrenergic alpha-Agonists; Adult; Analgesia; Analgesics; Analysis of Variance; Anesthetics, Local; Ankle; Clonidine; Double-Blind Method; Drug Combinations; Female; Foot Diseases; Hallux Valgus; Humans; Hypotension; Lidocaine; Male; Metatarsus; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Prospective Studies; Sensation; Time Factors; Toes | 1996 |
Clonidine and or adrenaline decrease lignocaine plasma peak concentration after epidural injection.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Anesthetics, Local; Area Under Curve; Clonidine; Drug Interactions; Drug Therapy, Combination; Epinephrine; Female; Half-Life; Humans; Injections, Epidural; Lidocaine; Male; Metabolic Clearance Rate; Middle Aged | 1996 |
Dose-range effects of clonidine added to lidocaine for brachial plexus block.
Topics: Adult; Aged; Anesthetics, Local; Blood Pressure; Brachial Plexus; Carpal Tunnel Syndrome; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Humans; Hypnotics and Sedatives; Lidocaine; Middle Aged; Nerve Block; Oxygen; Sympatholytics | 1997 |
[Influence of preanesthetic medication on the effect of a local anesthetic tape].
Topics: Adjuvants, Anesthesia; Administration, Topical; Adult; Aged; Anesthetics, Local; Anti-Anxiety Agents; Catheterization, Peripheral; Clonidine; Diazepam; Drug Interactions; Humans; Lidocaine; Middle Aged; Pain; Preanesthetic Medication; Sympatholytics | 1997 |
The optimal test dose of epinephrine for epidural injection with lidocaine solution in awake patients premedicated with oral clonidine.
Topics: Adult; Aged; Anesthesia, Epidural; Anesthetics, Local; Clonidine; Double-Blind Method; Epinephrine; Heart Rate; Humans; Lidocaine; Middle Aged; Preanesthetic Medication; Wakefulness | 1998 |
Enhancement of intrathecal lidocaine by addition of local and systemic clonidine.
Topics: Adrenergic alpha-Agonists; Aged; Analgesics; Anesthesia, Spinal; Anesthetics, Local; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Female; Femoral Neck Fractures; Fracture Fixation, Internal; Hemodynamics; Humans; Hysterectomy; Injections, Spinal; Lidocaine; Male; Middle Aged; Motor Neurons; Nerve Block; Neurons, Afferent; Phenylephrine; Prostatectomy | 1999 |
Adding clonidine to lidocaine for intravenous regional anesthesia prevents tourniquet pain.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Clonidine; Double-Blind Method; Female; Forearm; Hand; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Pain; Pain Measurement; Prospective Studies; Time Factors; Tourniquets | 1999 |
Intravenous regional anesthesia using lidocaine and clonidine.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Anesthetics, Local; Clonidine; Double-Blind Method; Hand; Humans; Lidocaine; Middle Aged; Pain, Postoperative; Sympathetic Nervous System | 1999 |
[Addition of clonidine to 0.5% lidocaine for intravenous locoregional anesthesia].
Topics: Adult; Analysis of Variance; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Double-Blind Method; Drug Combinations; Female; Humans; Ketoprofen; Lidocaine; Male; Pain Measurement; Pain, Postoperative | 2001 |
Plasma lidocaine concentrations during continuous thoracic epidural anesthesia after clonidine premedication in children.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Analgesics; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Child; Child, Preschool; Clonidine; Drug Interactions; Humans; Infant; Lidocaine; Male; Methyl Ethers; Preanesthetic Medication; Sevoflurane; Thoracic Vertebrae; Urologic Surgical Procedures | 2001 |
A dose response study of clonidine with local anesthetic mixture for peribulbar block: a comparison of three doses.
Topics: Adjuvants, Anesthesia; Anesthetics, Combined; Anesthetics, Local; Cataract Extraction; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Eye; Female; Humans; Lidocaine; Male; Middle Aged; Nerve Block | 2001 |
Effect of clonidine on lidocaine clearance in vivo: a microdialysis study in humans.
Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Local; Area Under Curve; Clonidine; Cold Temperature; Female; Humans; Injections, Intravenous; Lidocaine; Male; Microdialysis; Pain Measurement; Pain Threshold; Physical Stimulation; Regional Blood Flow | 2001 |
Effect of addition of clonidine to local anaesthetic mixture for peribulbar block.
Topics: Analgesics; Anesthetics, Local; Cataract Extraction; Clonidine; Double-Blind Method; Eye; Female; Humans; Hyaluronoglucosaminidase; Lidocaine; Male; Middle Aged; Nerve Block; Time Factors | 2002 |
The addition of sufentanil, tramadol or clonidine to lignocaine for intravenous regional anaesthesia.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Carpal Tunnel Syndrome; Clonidine; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Outcome Assessment, Health Care; Pain Measurement; Pain, Postoperative; Sufentanil; Tourniquets; Tramadol | 2004 |
General anaesthesia combined with bilateral paravertebral blockade (T5-6) vs. general anaesthesia for laparoscopic cholecystectomy: a prospective, randomized clinical trial.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Clonidine; Double-Blind Method; Female; Fentanyl; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Pain, Postoperative; Postoperative Nausea and Vomiting | 2004 |
[Effects of clonidine combined with various local anesthetics in brachial plexus block].
Topics: Adolescent; Adult; Amides; Analgesics; Anesthetics, Local; Brachial Plexus; Bupivacaine; Clonidine; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Ropivacaine | 2004 |
Surgery on the affected upper extremity of patients with a history of complex regional pain syndrome: the use of intravenous regional anesthesia with clonidine.
Topics: Anesthesia, Conduction; Anesthetics, Combined; Anesthetics, Intravenous; Clonidine; Complex Regional Pain Syndromes; Double-Blind Method; Female; Hand; Humans; Injections, Intravenous; Lidocaine; Male; Prospective Studies; Secondary Prevention | 2004 |
Clonidine as an adjuvant for lidocaine in axillary brachial plexus block in patients with chronic renal failure.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Aged; Anastomosis, Surgical; Anesthetics, Local; Blood Gas Analysis; Brachial Plexus; Clonidine; Conscious Sedation; Double-Blind Method; Female; Hemodynamics; Humans; Kidney Failure, Chronic; Lidocaine; Male; Middle Aged; Nerve Block; Oxygen; Prospective Studies | 2005 |
Comparison of clonidine and epinephrine in lidocaine anaesthesia for lower third molar surgery.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Anesthesia, Dental; Anesthetics, Local; Blood Pressure; Clonidine; Double-Blind Method; Epinephrine; Female; Heart Rate; Humans; Lidocaine; Male; Mandible; Middle Aged; Molar, Third; Nerve Block; Pain, Postoperative; Tooth Extraction; Vasoconstrictor Agents | 2005 |
Repetitive occipital nerve blockade for cervicogenic headache: expanded case report of 47 adults.
Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Cervical Vertebrae; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Electric Stimulation; Electrodiagnosis; Female; Fentanyl; Humans; Lidocaine; Male; Middle Aged; Neck Pain; Nerve Block; Post-Traumatic Headache; Prospective Studies; Spinal Nerves; Treatment Outcome | 2006 |
Occipital nerve blockade for cervicogenic headache: a double-blind randomized controlled clinical trial.
Topics: Adult; Anesthetics, Local; Bupivacaine; Cervical Vertebrae; Clonidine; Double-Blind Method; Drug Combinations; Electric Stimulation; Electrodes; Electrodiagnosis; Facial Nerve; Female; Fentanyl; Humans; Lidocaine; Male; Middle Aged; Neck Muscles; Nerve Block; Post-Traumatic Headache; Spinal Nerves; Treatment Outcome | 2006 |
Co-injection of clonidine prolongs the anesthetic effect of lidocaine skin infiltration by a peripheral action.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Clonidine; Double-Blind Method; Drug Combinations; Forearm; Humans; Injections, Subcutaneous; Lidocaine; Nerve Block; Pain Threshold; Reference Values; Skin; Time Factors | 2007 |
Lidocaine+clonidine for maxillary infiltration anaesthesia: parameters of anaesthesia and vascular effects.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics; Anesthesia, Local; Anesthetics, Local; Arteries; Blood Pressure; Clonidine; Double-Blind Method; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Lidocaine; Male; Maxilla; Molar, Third; Orbit; Pain Threshold; Pain, Postoperative; Sensation; Time Factors; Tissue Culture Techniques; Tooth Extraction; Tooth, Impacted; Vasoconstrictor Agents | 2008 |
Oral clonidine attenuates the fall in mean arterial pressure due to scalp infiltration with epinephrine-lidocaine solution in patients undergoing craniotomy: a prospective, randomized, double-blind, and placebo controlled trial.
Topics: Adolescent; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Local; Antihypertensive Agents; Blood Pressure; Clonidine; Craniotomy; Double-Blind Method; Epinephrine; Female; Humans; Lidocaine; Male; Middle Aged; Preanesthetic Medication; Prospective Studies; Vasoconstrictor Agents; Young Adult | 2009 |
Comparison of clonidine, local anesthetics, and placebo for pain reduction in pediatric tonsillectomy.
Topics: Adenoids; Adolescent; Age Factors; Analgesics; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Clonidine; Dehydration; Diet; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertrophy; Injections; Lidocaine; Male; Multivariate Analysis; Pain Measurement; Pain, Postoperative; Palatine Tonsil; Premedication; Prospective Studies; Sleep Apnea Syndromes; Tonsillectomy; Tonsillitis | 2011 |
A comparative clinical study of injection clonidine versus midazolam in supraclavicular brachial plexus block for sedation and postoperative analgesia: a study of 60 cases.
Topics: Adult; Analgesia; Analgesics; Brachial Plexus; Bupivacaine; Clonidine; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Postoperative Period; Time Factors; Young Adult | 2010 |
Supplementation of retrobulbar block with clonidine in vitreoretinal surgery: effect on postoperative pain.
Topics: Aged; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Clonidine; Double-Blind Method; Female; Hospitals, University; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Pain, Postoperative; Prospective Studies; Time Factors; Vitreoretinal Surgery | 2011 |
Is clonidine an adequate alternative to epinephrine as a vasoconstrictor in patients with hypertension?
Topics: Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Clonidine; Double-Blind Method; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Lidocaine; Male; Maxilla; Maxillary Nerve; Middle Aged; Molar, Third; Nerve Block; Pain, Postoperative; Safety; Time Factors; Tooth Extraction; Treatment Outcome; Vasoconstrictor Agents | 2012 |
Effect of clonidine added to lidocaine for sub-Tenon's (episcleral) anesthesia in cataract surgery.
Topics: Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Cataract Extraction; Clonidine; Double-Blind Method; Eye Movements; Female; Humans; Hyaluronoglucosaminidase; Lidocaine; Male; Middle Aged; Prospective Studies | 2014 |
Addition of clonidine or lignocaine to ropivacaine for supraclavicular brachial plexus block: a comparative study.
Topics: Adult; Amides; Analgesia; Anesthesia; Anesthetics; Anesthetics, Local; Antihypertensive Agents; Brachial Plexus Block; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lidocaine; Male; Middle Aged; Prospective Studies; Ropivacaine | 2014 |
Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers.
Topics: Adult; Analgesics; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Clonidine; Cross-Over Studies; Dental Pulp; Dental Pulp Test; Diabetes Mellitus, Type 2; Diastole; Double-Blind Method; Electrocardiography; Epinephrine; Heart Rate; Humans; Laser-Doppler Flowmetry; Lidocaine; Maxilla; Pain Measurement; Systole; Time Factors | 2016 |
Anaesthetic efficacy of lidocaine/clonidine for inferior alveolar nerve block in patients with irreversible pulpitis.
Topics: Adolescent; Adult; Anesthesia, Dental; Clonidine; Double-Blind Method; Epinephrine; Female; Humans; Injections; Lidocaine; Male; Mandible; Mandibular Nerve; Middle Aged; Molar; Nerve Block; Pulpitis; Young Adult | 2017 |
Anesthetic Success Using Nitrous Oxide and a Combination of Lidocaine/Clonidine for the Inferior Alveolar Nerve Block and the Effects on Blood Pressure and Pulse in Patients with Symptomatic Irreversible Pulpitis: A Prospective, Randomized, Double-blind S
Topics: Anesthesia, Dental; Anesthetics, Local; Blood Pressure; Clonidine; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Nitrous Oxide; Prospective Studies; Pulpitis | 2021 |
The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study.
Topics: Analgesics, Opioid; Anesthesia, General; Clonidine; Dexamethasone; Dexmedetomidine; Diazepam; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Isoflurane; Ketamine; Lidocaine; Magnesium Sulfate; Pain, Postoperative; Pilot Projects; Propofol; Rocuronium; Saline Solution | 2022 |
81 other study(ies) available for lidocaine and clonidine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
Reversible depression of electrically-induced contractions of guinea pig longitudinal muscle by a reversible inhibitor of prostaglandin synthetase.
Topics: Amidines; Animals; Chlorphenamidine; Clonidine; Cyclooxygenase Inhibitors; Guinea Pigs; Indomethacin; Lidocaine; Morphine; Muscle Contraction; Naloxone; Norepinephrine; Phentolamine; Prostaglandins E; Tolazoline | 1979 |
[The use of clofelin as a component in cerebrospinal anesthesia].
Topics: Adnexal Diseases; Adult; Aged; Anesthesia, Spinal; Clonidine; Evaluation Studies as Topic; Female; Humans; Hysterectomy; Lidocaine; Middle Aged; Ovarian Neoplasms | 1992 |
Clonidine enhances the effects of lidocaine on C-fiber action potential.
Topics: Action Potentials; Animals; Clonidine; Drug Interactions; Lidocaine; Membrane Potentials; Nerve Fibers; Rabbits; Tetrodotoxin | 1992 |
Isolated paced guinea pig left atrium: a new ouabain-induced arrhythmia model.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Function, Left; Clonidine; Disease Models, Animal; Drug Evaluation; Female; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Ouabain; Propranolol; Reproducibility of Results | 1991 |
Unusual complications of the treatment of chronic spinal arachnoiditis.
Topics: Aged; Analgesia, Epidural; Arachnoiditis; Chronic Disease; Clonidine; Female; Humans; Injections; Lidocaine; Morphine; Subarachnoid Space | 1990 |
Failure of epidural opioid to control cancer pain in a patient previously treated with massive doses of intravenous opioid.
Topics: Adenocarcinoma; Bupivacaine; Cecal Neoplasms; Clonidine; Female; Humans; Hydromorphone; Infusions, Intravenous; Injections, Epidural; Lidocaine; Middle Aged; Pain; Substance Withdrawal Syndrome | 1989 |
[Clinical effects of the addition of clonidine with and without adrenaline with peridural administration of lidocaine].
Topics: Anesthesia, Epidural; Clonidine; Epinephrine; Humans; Lidocaine; Pain, Postoperative | 1989 |
[Duration of analgesia after crural nerve block: effect of the addition of clonidine to xylocaine].
Topics: Adult; Analgesia; Clonidine; Humans; Lidocaine; Middle Aged; Nerve Block | 1989 |
Interaction of clonidine and morphine with lidocaine in mice and rats.
Topics: Animals; Blood Gas Analysis; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Hypoxia; Lethal Dose 50; Lidocaine; Male; Mice; Morphine; Rats; Yohimbine | 1989 |
[Clonidine enhances analgesia produced by epidural lidocaine].
Topics: Adolescent; Adult; Analgesia, Epidural; Clonidine; Drug Evaluation; Drug Synergism; Female; Humans; Lidocaine; Male | 1988 |
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium.
Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; Clonidine; Coronary Disease; Desipramine; Fluoxetine; Heart; Isomerism; Lidocaine; Male; Maprotiline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats.
Topics: Albuterol; Alprenolol; Animals; Atropine; Bethanidine; Blood Pressure; Cats; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Injections; Isoproterenol; Lidocaine; Male; Norepinephrine; Pempidine; Phentolamine; Practolol; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Sotalol; Species Specificity; Time Factors | 1974 |
Modulation of EPSP shape and efficacy by intrinsic membrane conductances in rat neocortical pyramidal neurons in vitro.
Topics: Animals; Cesium; Clonidine; Electric Conductivity; Evoked Potentials; In Vitro Techniques; Ion Channels; Lidocaine; Membrane Potentials; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses; Visual Cortex | 1993 |
Colonic giant migrating contractions induced by glycerol enema in anesthetized rats.
Topics: Animals; Atropine; Catheterization; Clonidine; Colon; Enema; Ganglionic Blockers; Gastrointestinal Motility; Glycerol; Hexamethonium; Hexamethonium Compounds; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar | 1993 |
Study of the sensitivity of the diabetes-induced pain model in rats to a range of analgesics.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Aspirin; Clonidine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Humans; Lidocaine; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 1994 |
The rostroventromedial medulla is not involved in alpha 2-adrenoceptor-mediated antinociception in the rat.
Topics: Analysis of Variance; Animals; Cerebellum; Clonidine; Dose-Response Relationship, Drug; Hot Temperature; Imidazoles; Lidocaine; Male; Medetomidine; Medulla Oblongata; Microinjections; Pain; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Reflex; Skin Temperature; Spinal Cord; Time Factors | 1993 |
Clonidine does not affect lidocaine seizure threshold in rats.
Topics: Animals; Blood Pressure; Carbon Dioxide; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Infusions, Intravenous; Lidocaine; Male; Oxygen; Rats; Rats, Wistar; Seizures; Time Factors | 1993 |
Hyperpolarizing afterpotentials in C fibers and local anesthetic effects of clonidine and lidocaine.
Topics: Action Potentials; Anesthetics, Local; Animals; Clonidine; Drug Interactions; Lidocaine; Nerve Fibers; Neural Conduction; Rabbits; Vagus Nerve | 1994 |
[Cancer pain: beneficial effect of ketamine addition to spinal administration of morphine-clonidine-lidocaine mixture].
Topics: Aged; Analgesics; Catheters, Indwelling; Clonidine; Drug Combinations; Drug Synergism; Female; Humans; Infusion Pumps; Injections, Spinal; Ketamine; Lidocaine; Male; Middle Aged; Morphine; Neoplasms; Pain; Pain Management | 1996 |
Antinociceptive interaction of intrathecal alpha2-adrenergic agonists, tizanidine and clonidine, with lidocaine in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Injections, Spinal; Lidocaine; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Yohimbine | 1997 |
The cold plate as a test of nociceptive behaviors: description and application to the study of chronic neuropathic and inflammatory pain models.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Chronic Disease; Clonidine; Cold Temperature; Hindlimb; Hot Temperature; Inflammation; Lidocaine; Morphine; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Skin Temperature; Stress, Mechanical; Wounds and Injuries | 1998 |
-Postoperative analgesia after major surgery of the knee.
Topics: Acetaminophen; Analgesia; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Bupivacaine; Clonidine; Humans; Knee Joint; Lidocaine; Ligaments, Articular; Morphine; Nerve Block; Pain, Postoperative; Physical Therapy Modalities; Sufentanil; Sympatholytics; Transcutaneous Electric Nerve Stimulation | 1998 |
[Analgesia in thoracic injuries: a comparative study of 2 techniques of loco-regional analgesia].
Topics: Adult; Aged; Analgesia; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Buprenorphine; Clonidine; Humans; Lidocaine; Male; Middle Aged; Pleura; Rib Fractures; Thoracic Injuries; Time Factors | 1998 |
Tizanidine protects mice against convulsions induced by lidocaine: involvement of alpha 2-adrenoceptors.
Topics: Animals; Anticonvulsants; Behavior, Animal; Clonidine; Drug Interactions; Lidocaine; Male; Mice; Phentolamine; Prazosin; Receptors, Adrenergic, alpha-2; Seizures; Time Factors; Yohimbine | 1999 |
Successful treatment of reflex sympathetic dystrophy by bier block with lidocaine and clonidine.
Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Cardiography, Impedance; Clonidine; Female; Humans; Injections, Spinal; Lidocaine; Monitoring, Physiologic; Muscle Contraction; Pain; Reflex Sympathetic Dystrophy; Sympatholytics | 1999 |
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice.
Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fentanyl; Lidocaine; Male; Mice; Morphine; Oxymetazoline; Pain; Pain Measurement; Pertussis Toxin; Temperature; Virulence Factors, Bordetella | 2000 |
Antinociceptive interaction between spinal clonidine and lidocaine in the rat formalin test: an isobolographic analysis.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Calcium Channels; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Formaldehyde; Injections, Spinal; Lidocaine; Male; Nerve Fibers; Pain; Potassium Channels; Rats; Rats, Sprague-Dawley | 2001 |
Group II muscle afferents probably contribute to the medium latency soleus stretch reflex during walking in humans.
Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Local; Ankle; Clonidine; Cold Temperature; Electromyography; Female; Foot; Humans; Ischemia; Lidocaine; Male; Muscle, Skeletal; Neurons, Afferent; Reaction Time; Reflex, Stretch; Time Factors; Walking | 2001 |
Peribulbar anaesthesia using a combination of lidocaine, bupivocaine and clonidine in vitreoretinal surgery.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Bupivacaine; Clonidine; Female; Humans; Injections; Lidocaine; Male; Middle Aged; Ophthalmologic Surgical Procedures; Patient Satisfaction; Prospective Studies; Retinal Diseases; Safety; Treatment Outcome; Vitrectomy | 2002 |
Allodynia after acute intrathecal morphine administration in a patient with neuropathic pain after spinal cord injury.
Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Anesthetics, Local; Clonidine; Humans; Injections, Spinal; Laminectomy; Lidocaine; Male; Morphine; Pain; Paraplegia; Spinal Cord Injuries | 2003 |
Epidural clonidine suppresses the baroreceptor-sympathetic response depending on isoflurane concentrations in cats.
Topics: Acidosis; Adrenergic alpha-Agonists; Anesthetics, Inhalation; Anesthetics, Local; Animals; Blood Pressure; Cats; Clonidine; Epidural Space; Female; Heart; Heart Rate; Injections; Isoflurane; Lidocaine; Male; Pressoreceptors; Sympathetic Nervous System | 2003 |
Multimodal spinal anesthesia.
Topics: Adult; Aged; Anesthesia, Spinal; Clonidine; Cystoscopy; Female; Humans; Lidocaine; Lithotripsy; Male; Middle Aged; Sufentanil | 2003 |
Effects of clonidine on lidocaine metabolism in human or rat liver microsomes.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Anesthetics, Local; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Humans; In Vitro Techniques; Lidocaine; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 2003 |
Substance P release in the cat spinal cord upon afferent C-fibre stimulation is not attenuated by clonidine at analgesic doses.
Topics: Afferent Pathways; Analgesics; Animals; Cats; Clonidine; Dose-Response Relationship, Drug; Down-Regulation; Electric Stimulation; Lidocaine; Nerve Fibers, Unmyelinated; Nociceptors; Pain; Presynaptic Terminals; Spinal Cord; Substance P; Synaptic Transmission | 2004 |
Seizures after a Bier block with clonidine and lidocaine.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Clonidine; Epilepsy, Complex Partial; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Reflex Sympathetic Dystrophy | 2004 |
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Brachial Plexus; Brachial Plexus Neuropathies; Celecoxib; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ketamine; Lidocaine; Male; Morphine; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Pyrazoles; Radiculopathy; Rats; Rats, Wistar; Sulfonamides | 2004 |
Clonidine prolongation of lidocaine analgesia after sciatic nerve block in rats Is mediated via the hyperpolarization-activated cation current, not by alpha-adrenoreceptors.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; In Vitro Techniques; Ion Channels; Lidocaine; Male; Nerve Block; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sciatic Nerve | 2004 |
[Combined use of local anesthetic with clonidine in cases of tooth extraction].
Topics: Adrenergic alpha-Agonists; Anesthesia, Local; Anesthetics, Local; Blood Pressure; Cardiovascular System; Clonidine; Dose-Response Relationship, Drug; Drug Combinations; Electrocardiography; Heart Rate; Humans; Injections; Lidocaine; Tooth Exfoliation; Vasoconstriction | 2005 |
A study of the in vitro interaction between lidocaine and premedications using human liver microsomes.
Topics: Animals; Cimetidine; Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Ketoconazole; Lidocaine; Microsomes, Liver; Midazolam; Neuromuscular Depolarizing Agents; Pentobarbital; Pharmacogenetics; Premedication; Rats; Theophylline; Thiamylal | 2005 |
The antinociceptive effect of local or systemic parecoxib combined with lidocaine/clonidine intravenous regional analgesia for complex regional pain syndrome type I in the arm.
Topics: Adrenergic alpha-Agonists; Aged; Analgesics; Anesthetics, Local; Arm; Clonidine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Female; Humans; Isoxazoles; Lidocaine; Male; Membrane Proteins; Middle Aged; Outpatients; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Reflex Sympathetic Dystrophy | 2005 |
Seizures after a Bier block with clonidine and lidocaine: is clonidine really the culprit?
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Drug Interactions; Humans; Lidocaine; Nerve Block; Rats; Seizures | 2005 |
The incidence of complex regional pain syndrome after fasciectomy for Dupuytren's contracture: a prospective observational study of four anesthetic techniques.
Topics: Aged; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Intravenous; Arm; Axilla; Clonidine; Complex Regional Pain Syndromes; Dupuytren Contracture; Fasciotomy; Female; Humans; Lidocaine; Male; Middle Aged; Nerve Block; Postoperative Complications; Tourniquets | 2006 |
Effects of premedication medicines on the formation of the CYP3A4-dependent metabolite of ropivacaine, 2', 6'-Pipecoloxylidide, on human liver microsomes in vitro.
Topics: Amides; Anesthetics, Local; Bupivacaine; Cells, Cultured; Cimetidine; Clonidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Humans; Lidocaine; Microsomes, Liver; Midazolam; Premedication; Ropivacaine; Thiamylal; Vecuronium Bromide | 2006 |
Clinical evaluation of clonidine added to lidocaine solution for subarachnoid analgesia in sheep.
Topics: Analgesia; Analgesics; Anesthetics, Combined; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Female; Lidocaine; Male; Sheep; Subarachnoid Space | 2006 |
Nerve-stimulator-guided repeated pudendal nerve block for treatment of pudendal neuralgia.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Clonidine; Electric Stimulation; Epinephrine; Female; Fentanyl; Genitalia; Humans; Lidocaine; Male; Medical Illustration; Middle Aged; Nerve Block; Neuralgia; Pain Measurement; Perineum; Peripheral Nerves; Recurrence; Treatment Outcome; Vasoconstrictor Agents | 2006 |
Repeated lumbar sympathetic blockade with lidocaine and clonidine attenuates pain in complex regional pain syndrome type 1 patients--a report of two cases.
Topics: Adult; Autonomic Nerve Block; Clonidine; Complex Regional Pain Syndromes; Humans; Lidocaine; Lumbosacral Region; Male | 2006 |
Effects of alpha2-adrenoceptor agonists on tetrodotoxin-resistant Na+ channels in rat dorsal root ganglion neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Resistance; Ganglia, Spinal; Lidocaine; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin; Yohimbine | 2007 |
Dexmedetomidine enhances the local anesthetic action of lidocaine via an alpha-2A adrenoceptor.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Lidocaine; Male; Oxymetazoline; Prazosin; Receptors, Adrenergic, alpha-2; Yohimbine | 2008 |
Successful but prolonged resuscitation after local anesthetic-induced cardiac arrest: is clonidine effective?
Topics: Adrenergic alpha-Agonists; Aged; Anesthetics, Local; Bupivacaine; Cardiopulmonary Resuscitation; Clonidine; Drug Therapy, Combination; Heart Arrest; Humans; Lidocaine; Lumbosacral Plexus; Male; Nerve Block; Time Factors | 2008 |
Effects of clonidine on lidocaine-induced inhibition of axonal transport in cultured mouse dorsal root ganglion neurones.
Topics: Adrenergic alpha-Agonists; Anesthetics, Local; Animals; Axonal Transport; Clonidine; Dose-Response Relationship, Drug; Ganglia, Spinal; Lidocaine; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; Neural Inhibition; Neurites; Organelles | 2008 |
Effects of pre-emptive drug treatment on astrocyte activation in the cuneate nucleus following rat median nerve injury.
Topics: Adrenergic alpha-Agonists; Animals; Astrocytes; Citrates; Clonidine; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Hyperalgesia; Lidocaine; Male; Median Neuropathy; Medulla Oblongata; Pain Threshold; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Up-Regulation | 2010 |
[Opioid induced cough: Do we know its pathophysiology and can it be eliminated?].
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Local; Clonidine; Cough; Fentanyl; Humans; Injections, Intravenous; Lidocaine; Reflex; Risk Factors | 2010 |
Intravenous regional block is similar to sympathetic ganglion block for pain management in patients with complex regional pain syndrome type I.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Local; Autonomic Nerve Block; Clonidine; Female; Ganglia, Sympathetic; Humans; Lidocaine; Male; Middle Aged; Pain Measurement; Reflex Sympathetic Dystrophy; Time Factors; Treatment Outcome | 2010 |
The influence of clonidine co-administration on the extent of lidocaine protein binding to rat serum and tissues.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Blood Proteins; Clonidine; Drug Synergism; Lidocaine; Mandible; Masseter Muscle; Muscle Proteins; Myocardium; Protein Binding; Rats; Rats, Wistar | 2011 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine | 2011 |
Be more vigilant when using clonidine as a vasoconstrictor for local anesthesia!
Topics: Anesthetics, Local; Antihypertensive Agents; Clonidine; Epinephrine; Female; Humans; Hypertension; Lidocaine; Male; Vasoconstrictor Agents | 2012 |
Adjuvants to prolong the local anesthetic effects of coated microneedle products.
Topics: Adjuvants, Pharmaceutic; Anesthetics, Local; Animals; Clonidine; Female; Guanfacine; Lidocaine; Microinjections; Needles; Prilocaine; Skin; Swine | 2012 |
Compounded ointment results in severe toxicity in a pediatric patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined Modality Therapy; Consciousness Disorders; Cyclohexanecarboxylic Acids; Diaper Rash; Drug Combinations; Drug Compounding; Drug Overdose; Emergencies; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Ketamine; Lidocaine; Male; Mefenamic Acid; Ointments; Reflex, Abnormal; Respiration Disorders; Skin Absorption | 2013 |
[The principles of pharmacotherapy of poststroke shoulder pain].
Topics: Amines; Amitriptyline; Anti-Inflammatory Agents; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Pregabalin; Shoulder Pain; Stroke | 2015 |
Prediction of inter-individual variability on the pharmacokinetics of CYP1A2 substrates in non-smoking healthy volunteers.
Topics: Area Under Curve; Caffeine; Clonidine; Cytochrome P-450 CYP1A2; Healthy Volunteers; Humans; Lidocaine; Monte Carlo Method; Phenacetin; Theophylline | 2016 |
Comparison of cardiovascular responses after injection of lidocaine with either clonidine or adrenaline: a two-year comparative analysis.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Local; Blood Pressure; Clonidine; Epinephrine; Female; Heart Rate; Humans; Injections; Lidocaine; Male; Mandibular Nerve; Middle Aged; Nerve Block; Tooth Extraction; Young Adult | 2017 |
Thoracic paravertebral catheterization for more than one year: A report of mastodynia.
Topics: Analgesics; Anesthetics, Local; Catheterization; Clonidine; Electric Injuries; Epidural Space; Female; Humans; Hyperalgesia; Lidocaine; Mastodynia; Middle Aged; Nerve Block; Pain Measurement; Thoracic Vertebrae; Time Factors; Treatment Outcome | 2018 |
Effect of opioid-free anaesthesia on postoperative epidural ropivacaine requirement after thoracic surgery: A retrospective unmatched case-control study.
Topics: Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Case-Control Studies; Clonidine; Female; Humans; Injections, Intravenous; Ketamine; Lidocaine; Male; Middle Aged; Morphine; Pain, Postoperative; Retrospective Studies; Ropivacaine; Thoracic Surgical Procedures; Thoracotomy; Time Factors | 2019 |
A sequential allocation study to determine the ED
Topics: Anesthesia, Conduction; Anesthetics, Local; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Lidocaine; Pain | 2022 |