lidocaine and chlorpheniramine

lidocaine has been researched along with chlorpheniramine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199012 (33.33)18.7374
1990's0 (0.00)18.2507
2000's13 (36.11)29.6817
2010's10 (27.78)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Chiang, GH; Unger, SH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Caron, G; Ermondi, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baum, T; Shropshire, AT1
Johnson, HL; Maibach, HI1
Katona, PG; Rigel, DF1
Altura, BM; Zweifach, BW1
Beckett, AH; Triggs, EJ1
Delorme, P1
Joshi, BK; Namaji, KJ; Sadre, NL; Tiwari, NM1
Doutre, LP; Périssat, J1
Baum, T; Eckfeld, DK; Rowles, G; Shropshire, AT; Varner, LL1
Bagnasco, G; Cometti, A; Maggi, N1
Liu, Q; Liu, Y; Pan, W; Yao, S1
Bilgin, F; Doğrul, A; Orhan, ME; Yüksel, U1
Fornés, L; Hernández-Pérez, M; Hossler, E; Lundberg, U; Paniz-Mondolfi, AE; Pérez-Alvarez, AM; Reyes-Jaimes, O1
Sanaei-Zadeh, H1
Dickson, N; Moles, I; Pallett, SJC1
Li, H; Li, P; Li, S; Wang, R1

Reviews

2 review(s) available for lidocaine and chlorpheniramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Different interventions for preventing postoperative catheter-related bladder discomfort: a systematic review and meta-analysis.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:6

    Topics: Chlorpheniramine; Dexmedetomidine; Gabapentin; Haloperidol; Humans; Ketamine; Lidocaine; Meperidine; Nefopam; Pain, Postoperative; Pregabalin; Tolterodine Tartrate; Tramadol; Urinary Bladder; Urinary Catheters

2022

Other Studies

34 other study(ies) available for lidocaine and chlorpheniramine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Octanol-physiological buffer distribution coefficients of lipophilic amines by reversed-phase high-performance liquid chromatography and their correlation with biological activity.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:3

    Topics: Amines; Animals; Buffers; Chromatography, High Pressure Liquid; Histamine Release; Lipid Metabolism; Octanols; Protein Binding; Rats; Serum Albumin, Bovine; Sodium-Potassium-Exchanging ATPase; Solubility; Structure-Activity Relationship

1981
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Central and peripheral contribution to the antihypertensive action of indoramin.
    European journal of pharmacology, 1975, Volume: 32, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cats; Chlorpheniramine; Electric Stimulation; Ganglia, Autonomic; Heart Conduction System; Heart Rate; Hypothalamus; Indoles; Indoramin; Lidocaine; Male; Sympathetic Nervous System; Synaptic Transmission

1975
Contact urticaria syndrome. Contact urticaria to diethyltoluamide (immediate-type hypersensitivity).
    Archives of dermatology, 1975, Volume: 111, Issue:6

    Topics: Adult; Ammonium Sulfate; Atropine; Benzamides; Benzocaine; Chlorpheniramine; DEET; Dermatitis, Contact; Diphenhydramine; Female; Histamine; Humans; Hypersensitivity, Immediate; Insect Repellents; Lidocaine; p-Methoxy-N-methylphenethylamine; Patch Tests; Urticaria

1975
Effects of antihistamines and local anesthetics on excess tachycardia in conscious dogs.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Anesthetics, Local; Animals; Atropine; Chlorpheniramine; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Lidocaine; Male; Procaine; Promethazine; Pyrilamine; Tachycardia

1986
Pharmacologic properties of antihistamines in relation to vascular reactivity.
    The American journal of physiology, 1965, Volume: 209, Issue:3

    Topics: Adrenalectomy; Animals; Atropine; Blood Circulation; Blood Vessels; Chlorpheniramine; Chlorpromazine; Diphenhydramine; Histamine; Histamine H1 Antagonists; Isoproterenol; Lidocaine; Mesentery; Phenoxybenzamine; Phentolamine; Promethazine; Rats; Serotonin; Vasomotor System; Yohimbine

1965
Buccal absorption of basic drugs and its application as an in vivo model of passive drug transfer through lipid membranes.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19

    Topics: Adult; Amines; Amphetamine; Appetite Depressants; Benzphetamine; Biological Transport; Chlorpheniramine; Chlorphentermine; Ephedrine; Fenfluramine; Furans; Humans; Hydrogen-Ion Concentration; Lidocaine; Male; Membranes; Meperidine; Mephentermine; Methadone; Models, Biological; Morpholines; Mouth; Nicotine; Phenethylamines; Phenmetrazine; Phenylpropanolamine

1967
Localized heat urticaria.
    The Journal of allergy, 1969, Volume: 43, Issue:5

    Topics: Adult; Anesthetics, Local; Chlorpheniramine; Desensitization, Immunologic; Female; Histamine H1 Antagonists; Hot Temperature; Humans; Hypersensitivity; Lidocaine; p-Methoxy-N-methylphenethylamine; Pollen; Procaine; Skin Tests; Sympathomimetics; Triamcinolone; Ultraviolet Rays; Urticaria

1969
Effect of some antihistaminic agents on the chronotropic response of adrenaline hydrochloride on isolated rat atria.
    Indian journal of medical sciences, 1970, Volume: 24, Issue:3

    Topics: Animals; Chlorpheniramine; Chlorpromazine; Epinephrine; Heart; Heart Atria; Heart Rate; Histamine H1 Antagonists; Imidazoles; Lidocaine; Procainamide; Prochlorperazine; Rats

1970
[Propofan as an antalgic in general surgery. Apropos of 50 cases].
    Bordeaux medical, 1972, Volume: 5, Issue:18

    Topics: Acetaminophen; Analgesics; Aspirin; Bone Diseases; Caffeine; Chlorpheniramine; Dextropropoxyphene; Drug Combinations; Fractures, Bone; Humans; Lidocaine; Peritoneal Diseases; Postoperative Care; Suppositories; Tablets; Wounds and Injuries

1972
Observations on models used for the evaluation of antiarrhythmic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Benzazepines; Bretylium Compounds; Chlorpheniramine; Diazepam; Disease Models, Animal; Dogs; Drug Antagonism; Guinea Pigs; Imipramine; Ketones; Lidocaine; Male; Meperidine; Mephentermine; Ouabain; Phentolamine; Phenytoin; Procainamide; Promazine; Promethazine; Propranolol; Quinidine

1971
GLC analysis of multicomponent suppository formulations.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:7

    Topics: Acetaminophen; Amides; Aminopyrine; Aspirin; Benzoates; Caffeine; Chlorpheniramine; Chromatography, Gas; Dextropropoxyphene; Ethylamines; Lidocaine; Malonates; Phenacetin; Sulfadimethoxine; Suppositories

1971
Study on the enhancement of Ru(bpy)3(2+) electrochemiluminescence by nanogold and its application for pentoxyverine detection.
    Electrophoresis, 2005, Volume: 26, Issue:23

    Topics: Chlorpheniramine; Cyclopentanes; Electrophoresis, Capillary; Gold; Lidocaine; Luminescent Measurements; Nanotechnology; Organometallic Compounds

2005
Comparison of the local anesthetic effects of chlorpheniramine, midazolam, lidocaine, and normal saline after intradermal injection.
    Medical science monitor : international medical journal of experimental and clinical research, 2007, Volume: 13, Issue:4

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Chlorpheniramine; Double-Blind Method; Female; Humans; Injections, Intradermal; Lidocaine; Male; Midazolam; Pain Measurement; Prospective Studies; Time Factors

2007
Cutaneous lepidopterism: dermatitis from contact with moths of Hylesia metabus (Cramer 1775) (Lepidoptera: Saturniidae), the causative agent of caripito itch.
    International journal of dermatology, 2011, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Anesthetics, Local; Animals; Antipruritics; Chlorpheniramine; Dermatitis, Contact; Dexamethasone; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Lidocaine; Loratadine; Male; Middle Aged; Moths; Pruritus; Treatment Outcome; Triamcinolone Acetonide; Venezuela

2011
Centipede bite.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:7

    Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Arthropods; Bites and Stings; Chlorpheniramine; Edema; Erythema; Humans; Hydrocortisone; Lidocaine; Male; Pain; Pentazocine; Tetanus Toxoid

2014
Challenges of Remote Medical Care in South Sudan: Centipede Bites.
    Wilderness & environmental medicine, 2019, Volume: 30, Issue:2

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Arthropod Venoms; Arthropods; Bites and Stings; Chlorpheniramine; Fentanyl; Histamine H1 Antagonists; Humans; Hydrocortisone; Lidocaine; Male; Military Personnel; Muscle Contraction; Pain; Pruritus; South Sudan

2019