lidocaine and carbamazepine

lidocaine has been researched along with carbamazepine in 78 studies

Research

Studies (78)

TimeframeStudies, this research(%)All Research%
pre-199020 (25.64)18.7374
1990's9 (11.54)18.2507
2000's19 (24.36)29.6817
2010's26 (33.33)24.3611
2020's4 (5.13)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Anger, T; Madge, DJ; Mulla, M; Riddall, D1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Barthelemy, MA; Bigg, D; Chabrier, PE; Huchet, M; Liberatore, AM; Pommier, J; Schulz, J1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Conradi, R; Lee, PH; Shanmugasundaram, V1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Sen, S; Sinha, N1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Cai, G; Cai, J; Calcul, L; Cheng, F; Jia, R; Li, C; Li, Q; Luo, X; She, F; Sun, X; Wang, D; Wang, S; Wang, Y; Wei, L; Yu, J; Zheng, M; Zhou, M1
Hazell, JW1
Goodey, RJ; Melding, PS1
Harell, M; Shea, JJ1
Jusić, A; Stimac-Crnosija, D1
Jusić, A; Sostarko, M; Vöglein, S1
Danielson, MG; Fowler, GW; Julien, RM1
Harker, LA; Murai, K; Stouffer, JL; Tyler, RS1
Backus, KH; Pflimlin, P; Trube, G1
Gries, FA; Ziegler, D1
Brose, WG; Tanelian, DL1
Bolton, CF; Hahn, AF; Parkes, AW; Stewart, SA1
Elliott, P1
Lajtha, A; Post, RM; Reith, ME; Weiss, SR; Zimányi, I1
Nierenberg, J; Post, RM; Szele, F; Weiss, SR; Woodward, R1
Gal, J; Molitoris, BA; Nakata, LM; Sedman, AJ1
Leppik, IE1
Lindblom, U; Lindström, P1
Hulshof, JH; Vermeij, P1
Hauswirth, O; Singh, BN1
Corbett, JJ; Tenser, RB1
Warfield, CA1
Goodey, RJ1
D'Arcy, PF1
Emmett, JR; Shea, JJ1
Zenk, KE1
Chuang, DM; Dick, D; Margolis, RL; Post, RM; Weiss, SR1
Erdö, SL; Lakics, V; Molnár, P1
Balbani, AP; Bento, RF; Bittar, RS; Câmara, J; Sanchez, TG1
Eldridge, PR; Knottenbelt, DC; Newton, SA1
Shannon, HE; Womer, DE1
Ghetti, A; Guia, A; Manalo, G; Santaana, D; Tao, H; Xie, B; Xu, J1
Maurya, PK; Mishra, VN; Pradhan, S; Yadav, R1
Carr, RW; De Col, R; Messlinger, K1
Cummins, TR; Heers, C; Sheets, PL; Stoehr, T1
Kitano, H; Shinohara, H; Zakir Hossain, SM1
Forde, G; Stanos, S1
Komatsu, M; Kubota, T; Nakajima, M; Okumura, A; Shimakawa, S; Tanabe, T1
Huang, CS; Kuo, CC; Yang, YC1
Johnson, EA; Parnell, BA; Zolnoun, DA1
Eliav, E; Haribabu, PK; Heir, GM1
Kobayashi, K; Kodani, N; Maniwa, S; Nakano, K; Ohtsuka, Y1
Bean, BP; Jo, S1
Tikhonov, DB; Zhorov, BS1
Bulusu, S; Buttle, SG; Dyment, D; Pohl, D; Sell, E1
Steinberg, DI1
Fedorova, IM; Tikhonov, DB1
Roses, S1
Acosta, MDC; Belmonte, C; Gallar, J; Luna, C; Meseguer, V; Mizerska, K; Quirce, S1
Araya, EI; Baggio, DF; Chichorro, JG; Koren, LO; Schwarting, RKW1
Sijm, DTHM; Tukker, AM; van Kleef, RGDM; Vrolijk, MF; Westerink, RHS1

Reviews

8 review(s) available for lidocaine and carbamazepine

ArticleYear
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke

2001
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Tinnitus.
    British journal of hospital medicine, 1979, Volume: 22, Issue:5

    Topics: Aspirin; Carbamazepine; Ear Diseases; Electric Stimulation Therapy; Hearing Loss, Noise-Induced; Humans; Lidocaine; Middle Aged; Nafronyl; Perceptual Masking; Tinnitus

1979
Review of pharmacologic treatment of tinnitus.
    The American journal of otology, 1992, Volume: 13, Issue:5

    Topics: Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Double-Blind Method; Female; Flunarizine; Humans; Lidocaine; Male; Streptomycin; Tinnitus

1992
Status epilepticus.
    Neurologic clinics, 1986, Volume: 4, Issue:3

    Topics: Adult; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Humans; Infant, Newborn; Lidocaine; Paraldehyde; Phenytoin; Status Epilepticus; Terminology as Topic; Valproic Acid

1986
Comparative mechanisms of action of antiarrhythmic drugs.
    American heart journal, 1974, Volume: 87, Issue:3

    Topics: Action Potentials; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Benzyl Compounds; Bretylium Compounds; Calcium; Carbamazepine; Chemical Phenomena; Chemistry; Diethylamines; Disopyramide; Heart; Humans; Imidazoles; Iodobenzoates; Lidocaine; Membrane Potentials; Phenyl Ethers; Phenytoin; Procainamide; Propylamines; Quinidine; Verapamil

1974
An overview of perinatal clinical pharmacology.
    Clinics in laboratory medicine, 1981, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline

1981
Practical management strategies for the chronic pain patient.
    The Journal of family practice, 2007, Volume: 56, Issue:8 Suppl Ho

    Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chronic Disease; Clinical Protocols; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged; Pain; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Substance-Related Disorders; Thiophenes; Treatment Outcome

2007

Trials

4 trial(s) available for lidocaine and carbamazepine

ArticleYear
The analgesic effect of tocainide in trigeminal neuralgia.
    Pain, 1987, Volume: 28, Issue:1

    Topics: Adult; Aged; Carbamazepine; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Tocainide; Trigeminal Neuralgia

1987
The value of carbamazepine in the treatment of tinnitus.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1985, Volume: 47, Issue:5

    Topics: Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Humans; Lidocaine; Middle Aged; Random Allocation; Tinnitus

1985
Lidocaine test in patients with tinnitus: rationale of accomplishment and relation to the treatment with carbamazepine.
    Auris, nasus, larynx, 1999, Volume: 26, Issue:4

    Topics: Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Local; Carbamazepine; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Tinnitus; Treatment Outcome

1999
Clinical trial of minimal treatment for clustering seizures in cases of convulsions with mild gastroenteritis.
    Brain & development, 2011, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Anesthetics, Local; Anticonvulsants; Carbamazepine; Child; Electroencephalography; Female; Gastroenteritis; Humans; Lidocaine; Male; Seizures; Young Adult

2011

Other Studies

66 other study(ies) available for lidocaine and carbamazepine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
2-Alkyl-4-arylimidazoles: structurally novel sodium channel modulators.
    Bioorganic & medicinal chemistry letters, 2004, Jul-05, Volume: 14, Issue:13

    Topics: Animals; Benzimidazoles; Binding Sites; Brain; Carbolines; Cells, Cultured; Electrophysiology; Inhibitory Concentration 50; Rats; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Veratridine

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR.
    Journal of medicinal chemistry, 2021, 08-12, Volume: 64, Issue:15

    Topics: Dose-Response Relationship, Drug; Drug Discovery; ErbB Receptors; Ligands; Molecular Structure; Peptidomimetics; Structure-Activity Relationship

2021
The treatment of tinnitus with oral anticonvulsants.
    The Journal of laryngology and otology, 1979, Volume: 93, Issue:2

    Topics: Administration, Oral; Adult; Aged; Carbamazepine; Female; Humans; Lidocaine; Male; Middle Aged; Phenytoin; Time Factors; Tinnitus

1979
Management of tinnitus aurium with lidocaine and carbamazepine.
    The Laryngoscope, 1978, Volume: 88, Issue:9 Pt 1

    Topics: Administration, Oral; Adult; Aged; Carbamazepine; Drug Evaluation; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Tinnitus

1978
[Genesis of dystrophia myotonica and its therapy with Tegretal and Xylocaine].
    Neurologija, 1978, Volume: 26, Issue:1-4

    Topics: Adult; Carbamazepine; Humans; Lidocaine; Male; Myotonic Dystrophy

1978
[Long-term effect of lignocaine on myotonic dystrophy and on the "stiff man" syndrome].
    Neuropsihijatrija, 1976, Volume: 24, Issue:1-4

    Topics: Adult; Carbamazepine; Female; Humans; Lidocaine; Male; Muscle Rigidity; Myotonic Dystrophy; Syndrome; Time Factors

1976
The effects of antiepileptic drugs on estrogen-induced electrographic spike-wave discharge.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 193, Issue:2

    Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Clonazepam; Clorazepate Dipotassium; Diazepam; Electroencephalography; Estrogens; Ethosuximide; Female; Imipramine; Lidocaine; Male; Motor Cortex; Phenytoin; Stereotaxic Techniques; Trimethadione

1975
Action of diazepam on the voltage-dependent Na+ current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil.
    Brain research, 1991, May-10, Volume: 548, Issue:1-2

    Topics: Action Potentials; Animals; Carbamazepine; Cell Line; Cells, Cultured; Diazepam; Embryo, Mammalian; Flumazenil; Kinetics; Lidocaine; Mice; Neuroblastoma; Neurons; Phenytoin; Sodium Channels; Spinal Cord

1991
[Treatment of pain in diabetic polyneuropathy].
    Deutsche medizinische Wochenschrift (1946), 1991, May-03, Volume: 116, Issue:18

    Topics: Analgesics; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Carbamazepine; Diabetic Neuropathies; Gangliosides; Humans; Lidocaine; Linolenic Acids; Mexiletine; Pain

1991
Neuropathic pain can be relieved by drugs that are use-dependent sodium channel blockers: lidocaine, carbamazepine, and mexiletine.
    Anesthesiology, 1991, Volume: 74, Issue:5

    Topics: Adult; Aged; Carbamazepine; Female; Humans; Lidocaine; Male; Mexiletine; Neuralgia; Peripheral Nerve Injuries; Sodium Channels

1991
Neuromyotonia in hereditary motor neuropathy.
    Journal of neurology, neurosurgery, and psychiatry, 1991, Volume: 54, Issue:3

    Topics: Adolescent; Anti-Arrhythmia Agents; Carbamazepine; Child; Electromyography; Female; Humans; Lidocaine; Male; Muscles; Myotonia Congenita; Myotonic Dystrophy; Neural Conduction; Neuromuscular Diseases; Pedigree; Peripheral Nerves; Peripheral Nervous System Diseases; Phenytoin; Tocainide

1991
Action of antiepileptic and anaesthetic drugs on Na- and Ca-spikes in mammalian non-myelinated axons.
    European journal of pharmacology, 1990, Jan-10, Volume: 175, Issue:2

    Topics: Action Potentials; Anesthetics; Animals; Anticonvulsants; Axons; Calcium; Carbamazepine; Dose-Response Relationship, Drug; Flurazepam; Lidocaine; Procaine; Rats; Rats, Inbred Strains; Sodium; Verapamil

1990
Evidence for a common site of action of lidocaine and carbamazepine in voltage-dependent sodium channels.
    European journal of pharmacology, 1989, Aug-29, Volume: 167, Issue:3

    Topics: Animals; Batrachotoxins; Carbamazepine; Female; Hippocampus; In Vitro Techniques; Lidocaine; Male; Phenytoin; Rats; Rats, Inbred Strains; Sodium Channels

1989
Chronic carbamazepine inhibits the development of local anesthetic seizures kindled by cocaine and lidocaine.
    Brain research, 1989, Sep-11, Volume: 497, Issue:1

    Topics: Anesthetics; Animals; Anticonvulsants; Carbamazepine; Cocaine; Dose-Response Relationship, Drug; Kindling, Neurologic; Lidocaine; Male; Rats; Rats, Inbred Strains

1989
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.
    American journal of nephrology, 1986, Volume: 6, Issue:2

    Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic; Lidocaine; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Valproic Acid; Vancomycin

1986
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; Facial Muscles; Facial Nerve; Glioma; Humans; Lidocaine; Male; Muscle Contraction; Muscular Diseases; Myoclonus; Nerve Block; Phenytoin; Volition

1974
Obturator neuropathy after forceps delivery.
    Obstetrics and gynecology, 1984, Volume: 64, Issue:3 Suppl

    Topics: Adult; Carbamazepine; Delivery, Obstetric; Female; Humans; Hyperesthesia; Lidocaine; Methylprednisolone; Nerve Block; Nerve Compression Syndromes; Obturator Nerve; Pain; Pain Management; Pregnancy

1984
Drugs in the treatment of tinnitus.
    Ciba Foundation symposium, 1981, Volume: 85

    Topics: Amobarbital; Antidepressive Agents, Tricyclic; Carbamazepine; Ethanol; Humans; Lidocaine; Phenytoin; Primidone; Tinnitus; Valproic Acid

1981
Early reports on drug interactions.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2

    Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine

1983
The medical treatment of tinnitus.
    The Journal of laryngology and otology. Supplement, 1981, Issue:4

    Topics: Adult; Carbamazepine; Diethylcarbamazine; Female; Humans; Lidocaine; Myoclonus; Phenytoin; Primidone; Tinnitus

1981
Effect of cocaine, lidocaine kindling and carbamazepine on batrachotoxin-induced phosphoinositide hydrolysis in rat brain slices.
    Brain research, 1993, Jun-18, Volume: 614, Issue:1-2

    Topics: Animals; Batrachotoxins; Brain Chemistry; Carbamazepine; Cocaine; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Kindling, Neurologic; Lidocaine; Male; Phosphatidylinositols; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sodium Channels

1993
Protection against veratridine toxicity in rat cortical cultures: relationship to sodium channel blockade.
    Neuroreport, 1995, Dec-29, Volume: 7, Issue:1

    Topics: Animals; Carbamazepine; Cell Death; Cells, Cultured; Cerebral Cortex; Lidocaine; Neuroprotective Agents; Patch-Clamp Techniques; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Veratridine; Vinca Alkaloids

1995
Headshaking in horses: possible aetiopathogenesis suggested by the results of diagnostic tests and several treatment regimes used in 20 cases.
    Equine veterinary journal, 2000, Volume: 32, Issue:3

    Topics: Anesthesia; Anesthetics, Local; Animals; Anti-Allergic Agents; Antimanic Agents; Carbamazepine; Contact Lenses; Cyproheptadine; Endoscopy; Female; Head; Head Movements; Horse Diseases; Horses; Lidocaine; Male; Masks; Mepivacaine; Radiography; Seasons; Tracheostomy; Trigeminal Nerve

2000
Pharmacologic reversal of pertussis toxin-induced thermal allodynia in mice.
    Neuropharmacology, 2000, Jul-24, Volume: 39, Issue:10

    Topics: Animals; Carbamazepine; Clonidine; Desipramine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fentanyl; Lidocaine; Male; Mice; Morphine; Oxymetazoline; Pain; Pain Measurement; Pertussis Toxin; Temperature; Virulence Factors, Bordetella

2000
Efficient characterization of use-dependent ion channel blockers by real-time monitoring of channel state.
    Assay and drug development technologies, 2006, Volume: 4, Issue:1

    Topics: Carbamazepine; Cell Line; Electrophysiology; Humans; Kinetics; Lamotrigine; Lidocaine; Membrane Potentials; Membrane Transport Modulators; Monitoring, Physiologic; Muscle Proteins; NAV1.4 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Reproducibility of Results; Sodium Channels; Tetracaine; Transfection; Triazines

2006
Focal myelomalacia and syrinx formation after accidental intramedullary lidocaine injection during lumbar anesthesia: a report of 3 cases.
    Journal of the neurological sciences, 2006, Dec-21, Volume: 251, Issue:1-2

    Topics: Adult; Amines; Anesthesia, Spinal; Anesthetics, Local; Carbamazepine; Cesarean Section; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Lidocaine; Lumbosacral Region; Magnetic Resonance Imaging; Spinal Cord Diseases

2006
Conduction velocity is regulated by sodium channel inactivation in unmyelinated axons innervating the rat cranial meninges.
    The Journal of physiology, 2008, Feb-15, Volume: 586, Issue:4

    Topics: Animals; Carbamazepine; Cyanides; Enzyme Inhibitors; Female; Lidocaine; Lithium; Male; Meninges; Nerve Fibers, Unmyelinated; Neural Conduction; Neurons, Afferent; Ouabain; Potassium; Rats; Rats, Wistar; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Synaptic Transmission; Tetrodotoxin

2008
Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 326, Issue:1

    Topics: Acetamides; Animals; Carbamazepine; Cell Line; Cells, Cultured; Humans; Lacosamide; Lidocaine; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels

2008
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
    Analytical chemistry, 2008, May-15, Volume: 80, Issue:10

    Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine

2008
Lidocaine, carbamazepine, and imipramine have partially overlapping binding sites and additive inhibitory effect on neuronal Na+ channels.
    Anesthesiology, 2010, Volume: 113, Issue:1

    Topics: Anesthetics, Local; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Binding Sites; Brain; Carbamazepine; Drug Synergism; Imipramine; Lidocaine; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Sodium Channels

2010
Genitofemoral and perineal neuralgia after transobturator midurethral sling.
    Obstetrics and gynecology, 2012, Volume: 119, Issue:2 Pt 2

    Topics: Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Autonomic Nerve Block; Carbamazepine; Female; Humans; Lidocaine; Lower Extremity; Middle Aged; Neuralgia; Pain, Postoperative; Perineum; Ropivacaine; Suburethral Slings; Vulva

2012
Topical medications for the effective management of neuropathic orofacial pain.
    Journal of the American Dental Association (1939), 2013, Volume: 144, Issue:6

    Topics: Administration, Topical; Amines; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperesthesia; Iatrogenic Disease; Ketoprofen; Lidocaine; Maxillary Nerve; Middle Aged; Neuralgia; Radicular Cyst

2013
Successful treatment of early myoclonic encephalopathy using lidocaine and carbamazepine.
    Epileptic disorders : international epilepsy journal with videotape, 2013, Volume: 15, Issue:3

    Topics: Anesthetics, Local; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Infant, Newborn; Lidocaine; Magnetic Resonance Imaging; Seizures; Spasm; Spasms, Infantile; Treatment Outcome

2013
Sidedness of carbamazepine accessibility to voltage-gated sodium channels.
    Molecular pharmacology, 2014, Volume: 85, Issue:2

    Topics: Carbamazepine; Cell Membrane Permeability; Cells, Cultured; Humans; Lidocaine; NAV1.7 Voltage-Gated Sodium Channel; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels

2014
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
    The Journal of general physiology, 2017, Apr-03, Volume: 149, Issue:4

    Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines

2017
Pointed rhythmic theta waves: a unique EEG pattern in KCNQ2-related neonatal epileptic encephalopathy.
    Epileptic disorders : international epilepsy journal with videotape, 2017, Sep-01, Volume: 19, Issue:3

    Topics: Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Female; Humans; Infant, Newborn; KCNQ2 Potassium Channel; Lidocaine; Spasms, Infantile; Treatment Outcome

2017
Review: In trigeminal neuralgia, carbamazepine, botulinum toxin type A, or lidocaine improve response rate vs placebo.
    Annals of internal medicine, 2018, 10-16, Volume: 169, Issue:8

    Topics: Botulinum Toxins, Type A; Carbamazepine; Humans; Lidocaine; Network Meta-Analysis; Trigeminal Neuralgia

2018
Lidocaine and carbamazepine inhibit while phenytoin and lamotrigine paradoxically enhance the insect neuromuscular transmission.
    Invertebrate neuroscience : IN, 2019, 02-08, Volume: 19, Issue:1

    Topics: Anesthetics, Local; Animals; Anticonvulsants; Carbamazepine; Diptera; Lamotrigine; Lidocaine; Phenytoin; Synaptic Transmission; Voltage-Gated Sodium Channel Blockers

2019
Neuralgia and Myself.
    Headache, 2019, Volume: 59, Issue:8

    Topics: Administration, Intranasal; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Carbamazepine; Female; Humans; Lidocaine; Paintings; Students, Medical; Trigeminal Neuralgia

2019
Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Nociceptive Corneal Nerves After Surgical Lesion.
    Investigative ophthalmology & visual science, 2021, 01-04, Volume: 62, Issue:1

    Topics: Amitriptyline; Animals; Carbamazepine; Carbon Dioxide; Cornea; Corneal Stroma; Electrophysiology; Female; Guinea Pigs; Lidocaine; Male; Nerve Fibers; Nerve Regeneration; Nociceptors; Ophthalmic Nerve; Sodium Channel Blockers; Surgical Flaps

2021
Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs.
    European journal of pharmacology, 2022, May-05, Volume: 922

    Topics: Analgesics; Animals; Carbamazepine; Hyperalgesia; Lidocaine; Male; Midazolam; Neuralgia; Rats; Trigeminal Neuralgia; Vocalization, Animal

2022
Mixture effects of tetrodotoxin (TTX) and drugs targeting voltage-gated sodium channels on spontaneous neuronal activity in vitro.
    Toxicology letters, 2023, Jan-15, Volume: 373

    Topics: Animals; Carbamazepine; Flecainide; Humans; Lidocaine; Rats; Riluzole; Tetrodotoxin; Voltage-Gated Sodium Channels

2023