lidocaine and capsaicin

lidocaine has been researched along with capsaicin in 167 studies

Research

Studies (167)

TimeframeStudies, this research(%)All Research%
pre-19909 (5.39)18.7374
1990's46 (27.54)18.2507
2000's45 (26.95)29.6817
2010's61 (36.53)24.3611
2020's6 (3.59)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Asakura, K; Kataura, A; Kojima, T; Narita, S; Shirasaki, H1
Håkanson, R; Wallengren, J1
Go, K; Namimatsu, A; Okuda, M; Tanimoto, H1
Hansson, L; Karlsson, JA; Midgren, B; Persson, CG; Simonsson, BG1
Izumi, H; Karita, K1
Fändriks, L; Hamlet, A; Jönson, C1
Dempsey, DT; Milner, R; Ritchie, WP; Sullivan, TR1
Deshpande, YG; Fitzgerald, S; Kaminski, DL; Nguyen, HQ1
Friedel, I; Hummel, C; Kobal, G; Thürauf, N1
Anderson, N; Choudry, NB; Fuller, RW; Karlsson, JA1
Bergren, DR1
McEvoy, RD; Reynolds, AM1
Barnes, PJ; Chung, KF; Lammers, JW; McCusker, MT; Minette, P1
Ravi, K1
Bachelard, H; Barabé, J; Rioux, F; St-Pierre, S1
Leyden, JJ; Soschin, D1
Erjefält, I; Persson, CG1
Cassidy, SS; Coast, JR; Monsereenusorn, Y1
Fukushima, T; Jin, Y; Morikawa, M; Nakazawa, H; Sasaki, H; Sekizawa, K1
Cho, CH; Ko, JK; Tang, XL1
Horie, T; Koyama, S; Matsumoto, K; Yamaguchi, M1
Park, HJ; Raymond, SA; Shin, HC1
Hansson, L; Karlsson, JA; Midgren, B1
Hottenstein, OD; Jacobson, ED; Remak, G2
Park, HJ; Raymond, SA; Shin, HC; Strichartz, GR1
Benaim, G; Giuliani, S; Lazzeri, M; Lecci, A; Maggi, CA; Turini, D1
Leung, FW1
Dempsey, DT; Mercer, DW; Ritchie, WP1
Titus, F1
Conte, B; Cutrufo, C; Manzini, S1
Inoue, K; Kunimoto, M; Masaki, T; Ogata, K; Takao, F1
Chandiramani, VA; Duthie, GS; Fowler, CJ; Peterson, T1
Pettit, MJ; Schwark, HD1
De Mey, JG; Jacobs, MJ; Kitslaar, PJ; Kurvers, HA; Reneman, RS; Rouwet, EV; Slaaf, DW; Tangelder, GJ; van den Wildenberg, FA1
Ravi, K; Singh, M1
Kobayashi, J; Ohta, M; Terada, Y1
McCafferty, DM; Sharkey, KA; Wallace, JL1
Laitin, S; Licht, D; Wallace, MS; Yaksh, TL1
Prystowsky, JB; Rege, RV1
Blandizzi, C; Carignani, D; Colucci, R; Del Tacca, M; Lazzeri, G1
Chisholm, K; Cousins, MJ; Vickers, ER; Walker, S1
Atsuta, S; Proud, D; Sanico, AM; Togias, A1
Dasgupta, P; Fowler, CJ; Stephen, RL1
Avelino, A; Coimbra, A; Cruz, F1
Belmonte, C; Brock, JA; McLachlan, EM1
Kasaba, T; Takasaki, M; Tanaka, N1
Grampp, W; Skogvall, S1
Damas, J; Liégeois, JF1
Maibach, HI; Rowbotham, MC; Yosipovitch, G1
Fuchs, PN; Meyer, RA; Pappagallo, M1
Nielsen, JB; Petersen, T; Schrøder, HD1
Chancellor, MB; De Groat, WC; Fraser, MO; Jung, SY; Ozawa, H; Yokoyama, O; Yoshiyama, M1
Baschiera, F; Blandizzi, C; Carignani, D; Colucci, R; Del Tacca, M; Lazzeri, G; Tognetti, M1
Koppert, W; Ostermeier, N; Schmelz, M; Sittl, R; Weidner, C1
Arendt-Nielsen, L; Gottrup, H; Hansen, PO; Jensen, TS1
Millqvist, E1
Haruma, K; Kajiyama, G; Nojima, K; Okahara, S; Sumii, K; Sumii, M; Yoshihara, M1
Kanamaru, A; Kojima, K; Mutoh, T; Nishimura, R; Sasaki, N; Tsubone, H1
Anand, A1
Dahl, JB; Dirks, J; Fabricius, P; Petersen, KL; Rowbotham, MC1
Arendt-Nielsen, L; Bach, FW; Gottrup, H; Jensen, TS1
Kanamaru, A; Kuwahara, M; Mutoh, T; Nishimura, R; Sasaki, N; Tsubone, H1
Avidan, A1
Abbott, PV; Verdickt, GM1
Dallel, R; Dubray, C; Ngom, PI; Woda, A1
Furness, JB; Khalil, Z; Kumano, K; Sanger, GJ; Timar-Peregrin, A1
Wang, W; Zhu, GQ; Zucker, IH1
Mailman, D1
Ahmad, M; Goucke, CR1
Helyes, Z; Jakab, B; Németh, J; Oroszi, G; Pintér, E; Szilvássy, Z; Szolcsányi, J1
Adcock, JJ; Beatch, G; Douglas, GJ; Garabette, M; Gascoigne, M; Page, CP; Walker, M1
Markley, HG1
SABETIAN, M1
Lao, LJ; Marvizón, JC; Song, B1
Bach, FW; Gottrup, H; Jensen, TS1
Ando, R; Kawamura, S; Watanabe, C; Yonezawa, A1
Baliki, M; Chidiac, JJ; Hawwa, N; Jabbur, SJ; Rifai, K; Saadé, NE1
Blumstein, H; Gorevic, PD1
Shyu, BC; Sun, JJ; Yang, JW1
Altschuler, E; Foye, PM; Stitik, TP1
Chambers, JP; Johnson, CB; Lizarraga, I1
Baron, R; Naleschinski, D; Wasner, G1
D'Arcy, Y; McCarberg, B1
Chen, MC; Klumpp, DJ; Mongiu, AK; Rudick, CN1
McCleskey, EW1
Bean, BP; Binshtok, AM; Woolf, CJ1
Agarwal, A; Dhiraaj, S; Gupta, D; Singh, PK; Tandon, M; Yadav, G1
Tyring, SK1
Fischer, MJ; Gavva, NR; Kienel, S; Kistner, K; Leffler, A; Nau, C; Reeh, PW; Rehner, D; Sauer, SK1
Chen, AD; De, W; Duan, YC; Gao, XY; Xu, B; Zhong, MK; Zhu, GQ1
Haraguchi, R; Iwanaga, T; Kubo, H; Muraki, M; Tohda, Y1
Beitz, AJ; Khasabov, SG; Pacharinsak, C; Simone, DA1
Hu, JW; Lam, DK; Sessle, BJ1
Deshpande, SB; Singh, SK1
Iwata, K; Kitagawa, J; Kondo, M; Masuda, Y; Miyamoto, M; Nitta-Kubota, I; Oi, Y; Ren, K; Shoda, E; Suzuki, I; Tsuboi, Y1
Gibson, SJ; Helme, RD; McMeeken, JM; Zheng, Z1
Chhabra, S; Garroway, N; Landis, S; Skolnik, DC1
Juszczak, K; Thor, PJ; Wyczolkowski, M; Ziomber, A1
Ahn, DK; Bean, BP; Binshtok, AM; Chung, G; Hwang, SJ; Jung, SJ; Kang, Y; Kim, HY; Kim, JS; Kim, K; Lee, MK; Li, HY; Oh, SB; Park, CK; Woolf, CJ1
Arendt-Nielsen, L; Boudreau, SA; Hennings, K; Sessle, BJ; Svensson, P1
Dahl, JB; Kehlet, H; Mathiesen, O1
Baron, R; Mahn, F1
Chen, SL; Dong, X; Fang, JY; Li, Y; Liu, ZL; Mo, JZ; Xiao, SD; Zhang, LY1
Lam, VY; Schulteis, G; Wallace, M1
Wilkins, BW1
Beggs, S; Kwan, C; Liu, XJ; Salter, MW1
Cheng, DS; Kennedy, DJ; Visco, CJ1
Bae, YC; Chung, G; Jo, HJ; Jung, SJ; Kim, HY; Kim, JS; Kim, YS; Oh, SB1
Armstrong, EP; Malone, DC; McCarberg, B; Panarites, CJ; Pham, SV1
Du, JQ; Li, Q; Liu, XH; Sun, N; Tang, JS; Zhu, JX1
Akiyuki, S; Kawamata, M; Kawamata, T; Shimizu, F; Tanaka, S1
Draxler, J; Gustorff, B; Hauer, D; Seis, A; Thaler, J1
Argoff, CE1
Amelink, GJ; Keppel Hesselink, JM; Kopsky, DJ1
Fan, ZD; Gan, XB; Gao, XY; Xiong, XQ; Zhang, L; Zhu, GQ1
Cheng, J; Fox, LE; Shen, J1
Juszczak, K; Thor, PJ1
Ahern, CA; Pless, SA; Rivera-Acevedo, RE; Schwarz, SK1
Binshtok, AM; Hitomi, S; Iwata, K; Kitagawa, J; Lev, S; Maeda, T; Mostafeezur, RM; Seo, K; Suzuki, A; Suzuki, I; Yamada, Y; Yamamura, K; Zakir, HM1
Chen, WW; Gao, XY; Han, Y; Xiong, XQ; Zhang, F; Zhou, YB; Zhu, GQ1
Bean, BP; Brenneis, C; Cobos, EJ; Ferreirós, N; Geisslinger, G; Ghasemlou, N; Kistner, K; Labocha, S; Puopolo, M; Reeh, PW; Roberson, D; Segal, D; Sisignano, M; Strominger, A; Woolf, CJ1
Bean, BP; Binshtok, AM; Oh, SB; Puopolo, M; Woolf, CJ; Yao, GL1
Agarwal, A; Gupta, D; Kishore, K; Rastogi, S; Singh, PK; Singh, U1
Dahan, A; Krebs-Brown, A; Martini, CH; Olofsen, E; Passier, P; Stoker, M; Yassen, A1
Bhattacharjee, A; Docherty, RJ; Ginsberg, L; Jadoon, S; Orrell, RW1
Heir, GM; Khan, J; Nasri-Heir, C1
Knolle, E; Kovacs, GG; Medwed, S; Scharbert, G; Schemper, M; Zadrazil, M1
Ahn, JS; Badral, B; Chung, G; Davies, AJ; Hong, SD; Kim, JS; Kim, YH; Oh, SB1
Büchel, C; Geuter, S; Schenk, LA; Sprenger, C1
Kern, KU; Nowack, W; Poole, C1
Lü, H; Qiu, Z; Wang, L; Xu, X; Yang, Z; Yu, L1
Aschenbrenner, CA; Eisenach, JC; Houle, TT; Peters, CM; Ririe, D1
Galluzzi, KE; Stanos, SP1
Goßrau, G1
Ernault, E; Fricová, J; Høye, K; Jensen, TS; Marques, S; Siciliano, T; Vanelderen, P1
Andresen, MC; Fawley, JA; Hofmann, ME; Largent-Milnes, TM1
Benedetti, F; Finnerup, NB; Grosen, K; Jensen, TS; Petersen, GL; Pilegaard, HK; Price, DD; Tracey, I; Vase, L1
Johnson, RW; Rice, AS1
Chen, X; Claggett, B; Egorova, N; Freeman, S; Gollub, RL; Kaptchuk, TJ; Kirsch, I; Kong, J; Yu, R1
Frank, JA; Lewin, GR; Moroni, M; Moshourab, R; Sumser, M; Trauner, D1
Abdulnour, RE; Agac, B; Bean, BP; Burkett, PR; Chiu, IM; Cronin, SJ; DiBiase, M; Foster, SL; Ghasemlou, N; Haworth, O; Kuchroo, VK; Laedermann, C; Lai, N; Lee, S; Levy, BD; Pascal, MA; Penninger, JM; Roberson, D; Seki, H; Talbot, S; Tran, JV; Von Hehn, C; Woolf, CJ1
Bang, S; Berta, T; Ji, RR; Kim, YH; Oh, SB; Wang, F; Xu, ZZ; Zhang, Y1
Kern, KU; Weiser, T1
Di Stasio, D; Gentile, E; Guida, A; Lauritano, D; Lucchese, A; Maio, C; Petruzzi, M; Salerno, C; Serpico, R; Tammaro, M1
Gibbs, LM; Lindsay, TJ; Snyder, MJ1
Paisley, P; Serpell, M1
Arendt-Nielsen, L; Cairns, BE; Wang, K; Zhang, Y1
Delorme, C; Martin, E; Mick, G; Pickering, G; Tiberghien, F1
Béjar, J; Chávez, D; Contreras-Hernández, E; Cortés, U; Glusman, S; Hernández, E; Martín, M; Reyes, P; Rudomin, P; Velázquez, E1
Baron, R; Binder, A; Enax-Krumova, EK; Geisslinger, G; Gierthmühlen, J; Henrich, F; Hüllemann, P; Klein, T; Lötsch, J; Magerl, W; Maier, C; Oertel, B; Schuh-Hofer, S; Tölle, TR; Treede, RD; Vollert, J1
Kern, KU; Schwickert-Nieswandt, M1
Araya, EI; Chichorro, JG; Claudino, RF; de Oliveira, SB; Ferreira, LEN; Franz-Montan, M; Gambeta, E1
Brozmanova, M; Buday, T; Svajdova, S1
Hu, Y; Yu, S; Yu, X1
Chen, W; Fu, W; Marvizon, JC; Taylor, BK1
Kaisler, M; Kumowski, N; Maier, C; Meyer-Frießem, CH; Schwarzer, A1
Lucchini, C; Pickering, G1
Cohrs, J; Kerns, R1
Lin, K; Liu, X; Wei, L; Zeng, Q; Zhang, J1
Freeman, J; Gupta, R; Maloney, J; Pew, S; Strand, N; Wie, C1
Almeshal, D; Fontaine, R; Hans, GH; Investigators Team, TP; Roelant, E; Smits, E; Van Boxem, K; Vanlommel, L; Verhaegen, I1

Reviews

24 review(s) available for lidocaine and capsaicin

ArticleYear
[Symptomatic treatment of cluster headache].
    Revista de neurologia, 1995, Volume: 23 Suppl 4

    Topics: Alkaloids; Analgesics; Capsaicin; Cluster Headache; Cocaine; Dihydroergotamine; Ergotamine; Humans; Lidocaine; Methoxyflurane; Narcotics; Oxygen; Sumatriptan; Vasoconstrictor Agents

1995
Management strategies for the treatment of neuropathic pain in the elderly.
    Drugs & aging, 2002, Volume: 19, Issue:12

    Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Anticonvulsants; Antidepressive Agents; Capsaicin; Cognitive Behavioral Therapy; Diabetic Neuropathies; Herpes Simplex; Humans; Lidocaine; Nerve Block; Nervous System Diseases; Neuralgia; Pain; Pain Management; Physical Therapy Modalities; Stroke; Tramadol

2002
Topical agents in the treatment of cluster headache.
    Current pain and headache reports, 2003, Volume: 7, Issue:2

    Topics: Administration, Intranasal; Administration, Topical; Capsaicin; Cluster Headache; Cocaine; Dihydroergotamine; Humans; Lidocaine; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents

2003
Rheumatologic illnesses: treatment strategies for older adults.
    Geriatrics, 2005, Volume: 60, Issue:6

    Topics: Adjuvants, Immunologic; Administration, Topical; Aged; Aging; Analgesics; Anesthetics, Local; Arthritis; Capsaicin; Cognitive Behavioral Therapy; Exercise; Humans; Hyaluronic Acid; Injections, Intra-Articular; Lidocaine; Patient Education as Topic; Self-Help Devices

2005
Pharmacotherapy of osteoarthritis.
    American journal of physical medicine & rehabilitation, 2006, Volume: 85, Issue:11 Suppl

    Topics: Acetaminophen; Administration, Topical; Analgesics; Anesthetics, Local; Capsaicin; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Injections, Intra-Articular; Lidocaine; Osteoarthritis; Salicylates; Tramadol

2006
Target pain with topical peripheral analgesics.
    The Nurse practitioner, 2007, Volume: 32, Issue:7

    Topics: Administration, Topical; Aged; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Female; Hot Temperature; Humans; Lidocaine; Osteoarthritis, Knee; Pain; Pain Management; Peripheral Nervous System Agents

2007
Management of herpes zoster and postherpetic neuralgia.
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:6 Suppl

    Topics: Adrenal Cortex Hormones; Aged; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Antiviral Agents; Capsaicin; Drug Administration Schedule; Drug Therapy, Combination; Herpes Zoster; Humans; Lidocaine; Middle Aged; Neuralgia, Postherpetic; Palliative Care

2007
Clinical inquiries: What measures relieve postherpetic neuralgia?
    The Journal of family practice, 2009, Volume: 58, Issue:7

    Topics: Administration, Oral; Administration, Topical; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Evidence-Based Medicine; Family Practice; Female; Follow-Up Studies; Humans; Lidocaine; Male; Neuralgia, Postherpetic; Pain Measurement; Randomized Controlled Trials as Topic; Risk Assessment; Severity of Illness Index

2009
An expert opinion on postoperative pain management, with special reference to new developments.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:15

    Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Capsaicin; Disease Management; gamma-Aminobutyric Acid; Humans; Lidocaine; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic

2010
Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia.
    Current medical research and opinion, 2011, Volume: 27, Issue:5

    Topics: Administration, Topical; Amines; Anesthetics, Local; Antidepressive Agents, Tricyclic; Capsaicin; Clinical Trials as Topic; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Markov Chains; Neuralgia, Postherpetic; Pregabalin; Quality of Life; Sensory System Agents; Thiophenes; Transdermal Patch

2011
[Potentials for differential block with local anesthetics].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59 Suppl

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Bupivacaine; Capsaicin; Drug Design; Humans; Levobupivacaine; Lidocaine; Nociceptors; Physical Stimulation; Sodium Channel Blockers; Sodium Channels; TRPV Cation Channels

2010
Review of current guidelines on the care of postherpetic neuralgia.
    Postgraduate medicine, 2011, Volume: 123, Issue:5

    Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Capsaicin; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia, Postherpetic; Practice Guidelines as Topic; Pregabalin; Primary Health Care; Tramadol; Transdermal Patch

2011
[Capsaicin and lidocaine usage in functional disorders of urinary bladder].
    Folia medica Cracoviensia, 2011, Volume: 51, Issue:1-4

    Topics: Botulinum Toxins; Calcium Channels; Capsaicin; Cholinergic Antagonists; Drug Therapy, Combination; Humans; Lidocaine; Nerve Tissue Proteins; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels; Urinary Bladder, Overactive

2011
Topical medications as treatment of neuropathic orofacial pain.
    Dental clinics of North America, 2013, Volume: 57, Issue:3

    Topics: Administration, Cutaneous; Capsaicin; Cyclooxygenase Inhibitors; Diclofenac; Facial Pain; Humans; Lidocaine; Neuralgia; Sensory System Agents; Voltage-Gated Sodium Channel Blockers

2013
Topical therapies in the management of chronic pain.
    Postgraduate medicine, 2013, Volume: 125, Issue:4 Suppl 1

    Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chronic Pain; Diclofenac; Humans; Ibuprofen; Irritants; Ketoprofen; Lidocaine; Musculoskeletal Pain; Neoplasms; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis, Knee; Palliative Care

2013
[Postherpetic neuralgia].
    Schmerz (Berlin, Germany), 2014, Volume: 28, Issue:1

    Topics: Administration, Topical; Aged; Analgesics; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Antiviral Agents; Capsaicin; Cooperative Behavior; Cross-Sectional Studies; Herpes Zoster Vaccine; Humans; Interdisciplinary Communication; Lidocaine; Middle Aged; Neuralgia, Postherpetic; Pain Management; Pain Measurement; Randomized Controlled Trials as Topic

2014
Clinical practice. Postherpetic neuralgia.
    The New England journal of medicine, 2014, Oct-16, Volume: 371, Issue:16

    Topics: Administration, Topical; Aged; Amines; Analgesics, Opioid; Anesthetics, Local; Antipyretics; Capsaicin; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Herpes Zoster Vaccine; Humans; Lidocaine; Neuralgia, Postherpetic; Pregabalin

2014
An overview of burning mouth syndrome.
    Frontiers in bioscience (Elite edition), 2016, 01-01, Volume: 8, Issue:1

    Topics: Benzylamines; Burning Mouth Syndrome; Capsaicin; Clonazepam; Humans; Lidocaine; Prevalence

2016
Treating Painful Diabetic Peripheral Neuropathy: An Update.
    American family physician, 2016, Aug-01, Volume: 94, Issue:3

    Topics: Administration, Topical; Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anesthetics, Local; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Isosorbide Dinitrate; Lidocaine; Phenols; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin and Noradrenaline Reuptake Inhibitors; Tapentadol; Tramadol; Transcutaneous Electric Nerve Stimulation; Vasodilator Agents; Venlafaxine Hydrochloride

2016
The role of topiceuticals in cancer pain.
    Current opinion in supportive and palliative care, 2017, Volume: 11, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Cancer Pain; Capsaicin; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Humans; Lidocaine; Menthol; Neuralgia; Pain Management; Pain Measurement

2017
Localized neuropathic pain: an expert consensus on local treatments.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Administration, Topical; Aged; Analgesics; Anesthetics, Local; Animals; Capsaicin; Humans; Lidocaine; Neuralgia; Quality of Life; Randomized Controlled Trials as Topic

2017
Topical Treatment of Localized Neuropathic Pain in the Elderly.
    Drugs & aging, 2020, Volume: 37, Issue:2

    Topics: Administration, Topical; Aged; Aged, 80 and over; Analgesics; Capsaicin; Humans; Lidocaine; Middle Aged; Neuralgia

2020
The Treatment of Topical Drugs for Postherpetic Neuralgia: A Network Meta-Analysis.
    Pain physician, 2020, Volume: 23, Issue:6

    Topics: Bayes Theorem; Capsaicin; Humans; Lidocaine; Network Meta-Analysis; Neuralgia, Postherpetic; Pharmaceutical Preparations; Quality of Life

2020
Comprehensive Review of Topical Analgesics for Chronic Pain.
    Current pain and headache reports, 2021, Feb-03, Volume: 25, Issue:2

    Topics: Administration, Topical; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Antipruritics; Capsaicin; Chronic Pain; Humans; Lidocaine

2021

Trials

25 trial(s) available for lidocaine and capsaicin

ArticleYear
Capsaicin-induced cough in humans.
    The American review of respiratory disease, 1992, Volume: 146, Issue:2

    Topics: Administration, Inhalation; Adolescent; Adult; Capsaicin; Citrates; Citric Acid; Cough; Dose-Response Relationship, Drug; Humans; Lidocaine; Male; Middle Aged; Reproducibility of Results

1992
Effects of inhaled lignocaine and adrenaline on capsaicin-induced cough in humans.
    Thorax, 1994, Volume: 49, Issue:11

    Topics: Administration, Inhalation; Adolescent; Adult; Capsaicin; Cough; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; Humans; Lidocaine; Male

1994
Concentration-effect relations for intravenous lidocaine infusions in human volunteers: effects on acute sensory thresholds and capsaicin-evoked hyperpathia.
    Anesthesiology, 1997, Volume: 86, Issue:6

    Topics: Adolescent; Adult; Anesthetics, Local; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Hot Temperature; Humans; Hyperalgesia; Infusion Pumps; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Pain Measurement; Pain Threshold; Placebos; Sensory Thresholds; Skin Temperature

1997
Analysis of 50 patients with atypical odontalgia. A preliminary report on pharmacological procedures for diagnosis and treatment.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 85, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anesthetics, Combined; Anesthetics, Local; Capsaicin; Chi-Square Distribution; Chronic Disease; Facial Pain; Female; Humans; Infusions, Intravenous; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Pain Measurement; Phentolamine; Prilocaine; Reflex Sympathetic Dystrophy; Sex Factors; Single-Blind Method; Surveys and Questionnaires; Sympatholytics; Temporomandibular Joint Disorders; Toothache

1998
Plasma extravasation through neuronal stimulation in human nasal mucosa in the setting of allergic rhinitis.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:2

    Topics: Adult; Aged; Anesthetics, Local; Atropine; Bradykinin; Capillary Permeability; Capsaicin; Female; Fibrinogen; Humans; Lidocaine; Male; Middle Aged; Nasal Lavage Fluid; Nasal Mucosa; Nasal Provocation Tests; Neurons, Afferent; Parasympatholytics; Rhinitis, Allergic, Perennial; Serum Albumin

1998
Effect of EMLA pre-treatment on capsaicin-induced burning and hyperalgesia.
    Acta dermato-venereologica, 1999, Volume: 79, Issue:2

    Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Capsaicin; Female; Humans; Hyperalgesia; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Pain Threshold; Paresthesia; Premedication; Prilocaine; Reference Values; Severity of Illness Index; Single-Blind Method; Treatment Outcome

1999
Topical EMLA pre-treatment fails to decrease the pain induced by 1% topical capsaicin.
    Pain, 1999, Volume: 80, Issue:3

    Topics: Administration, Topical; Adult; Anesthetics, Local; Capsaicin; Drug Tolerance; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Neuralgia; Pain Threshold; Prilocaine

1999
Intravesical capsaicin in patients with detrusor hyper-reflexia--a placebo-controlled cross-over study.
    Scandinavian journal of urology and nephrology, 1999, Volume: 33, Issue:2

    Topics: Administration, Intravesical; Anesthetics, Local; Capsaicin; Cross-Over Studies; Female; Humans; Lidocaine; Male; Middle Aged; Premedication; Reflex, Abnormal; Spinal Cord Diseases; Substance P; Time Factors; Urinary Bladder; Urinary Bladder, Neurogenic; Urodynamics

1999
Low-dose lidocaine reduces secondary hyperalgesia by a central mode of action.
    Pain, 2000, Volume: 85, Issue:1-2

    Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Axons; Capsaicin; Double-Blind Method; Female; Humans; Hyperalgesia; Injections, Intravenous; Laser-Doppler Flowmetry; Lidocaine; Male; Middle Aged; Pain Measurement

2000
Differential effects of systemically administered ketamine and lidocaine on dynamic and static hyperalgesia induced by intradermal capsaicin in humans.
    British journal of anaesthesia, 2000, Volume: 84, Issue:2

    Topics: Analgesics; Anesthetics, Local; Capsaicin; Cross-Over Studies; Double-Blind Method; Hot Temperature; Humans; Hyperalgesia; Ketamine; Lidocaine; Male; Pain Measurement; Pain Threshold; Touch

2000
Cough provocation with capsaicin is an objective way to test sensory hyperreactivity in patients with asthma-like symptoms.
    Allergy, 2000, Volume: 55, Issue:6

    Topics: Administration, Inhalation; Adult; Anesthetics, Local; Asthma; Capsaicin; Cough; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Multiple Chemical Sensitivity; Placebos

2000
The effect of systemic lidocaine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adult; Anesthetics, Local; Capsaicin; Cross-Over Studies; Dizziness; Double-Blind Method; Hot Temperature; Humans; Hyperalgesia; Infusions, Intravenous; Injections, Intravenous; Lidocaine; Male; Nociceptors; Pain; Pain Measurement; Pain Threshold; Placebos; Skin; Sleep Stages; Vision Disorders; Xerostomia

2000
Peripheral lidocaine but not ketamine inhibits capsaicin-induced hyperalgesia in humans.
    British journal of anaesthesia, 2000, Volume: 85, Issue:4

    Topics: Analgesics; Analysis of Variance; Anesthetics, Local; Capsaicin; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Ketamine; Lidocaine; Male; Pain Measurement; Touch

2000
Differential effects of peripheral ketamine and lidocaine on skin flux and hyperalgesia induced by intradermal capsaicin in humans.
    Clinical physiology and functional imaging, 2004, Volume: 24, Issue:2

    Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Capsaicin; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Injections, Subcutaneous; Ketamine; Lidocaine; Male; Pain; Skin

2004
Comparative evaluation of myolaxin and EMLA cream for attenuation of venous cannulation pain: a prospective, randomised, double blind study.
    Anaesthesia and intensive care, 2007, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Capsaicin; Catheterization, Peripheral; Double-Blind Method; Female; Humans; Incidence; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Pain; Pain Measurement; Prilocaine; Prospective Studies; Statistics, Nonparametric; Veins

2007
The effect of local anaesthetic on age-related capsaicin-induced mechanical hyperalgesia--a randomised, controlled study.
    Pain, 2009, Volume: 144, Issue:1-2

    Topics: Adult; Aged; Aging; Analysis of Variance; Anesthetics, Local; Capsaicin; Female; Humans; Hyperalgesia; Lidocaine; Male; Pain Measurement; Personality; Procaine; Psychophysics; Sex Factors; Time Factors; Young Adult

2009
The effects of training time, sensory loss and pain on human motor learning.
    Journal of oral rehabilitation, 2010, Volume: 37, Issue:9

    Topics: Adult; Anesthetics, Local; Capsaicin; Feedback, Sensory; Female; Follow-Up Studies; Humans; Learning; Lidocaine; Male; Motor Skills; Muscle Fatigue; Pain; Reaction Time; Sensation; Sensory System Agents; Stress, Mechanical; Time Factors; Tongue; Touch; Touch Perception; Young Adult

2010
Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial.
    The journal of pain, 2011, Volume: 12, Issue:3

    Topics: Anesthetics, Local; Capsaicin; Double-Blind Method; Humans; Hyperalgesia; Injections, Intradermal; Lidocaine; Pain; Pain Measurement; Pain Threshold; Time Factors; Transdermal Patch

2011
Antihyperalgesic efficacy of 5% lidocaine medicated plaster in capsaicin and sunburn pain models--two randomized, double-blinded, placebo-controlled crossover trials in healthy volunteers.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:18

    Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Capsaicin; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hyperalgesia; Lidocaine; Neuralgia; Pain Measurement; Physical Stimulation; Sunburn; Treatment Outcome; Young Adult

2011
A comparative evaluation of local application of the combination of eutectic mixture of local anesthetics and capsaicin for attenuation of venipuncture pain.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Capsaicin; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Ointments; Pain; Pain Measurement; Phlebotomy; Prilocaine; Prospective Studies; Young Adult

2013
A novel approach to identify responder subgroups and predictors of response to low- and high-dose capsaicin patches in postherpetic neuralgia.
    European journal of pain (London, England), 2013, Volume: 17, Issue:10

    Topics: Aged; Aged, 80 and over; Capsaicin; Chronic Pain; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Neuralgia, Postherpetic; Transdermal Patch; Treatment Outcome

2013
Comparison of cooling and EMLA to reduce the burning pain during capsaicin 8% patch application: a randomized, double-blind, placebo-controlled study.
    Pain, 2013, Volume: 154, Issue:12

    Topics: Adult; Capsaicin; Cryotherapy; Double-Blind Method; Female; Follow-Up Studies; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Ointments; Pain; Pain Management; Pain Measurement; Prilocaine; Transdermal Patch; Young Adult

2013
Tolerability of the capsaicin 8% patch following pretreatment with lidocaine or tramadol in patients with peripheral neuropathic pain: a multicentre, randomized, assessor-blinded study.
    European journal of pain (London, England), 2014, Volume: 18, Issue:9

    Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Capsaicin; Female; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Pain Measurement; Premedication; Sensory System Agents; Single-Blind Method; Tramadol; Transdermal Patch; Treatment Outcome

2014
γ-Aminobutyric acid (GABA) oral rinse reduces capsaicin-induced burning mouth pain sensation: An experimental quantitative sensory testing study in healthy subjects.
    European journal of pain (London, England), 2018, Volume: 22, Issue:2

    Topics: Adult; Analgesics; Capsaicin; Cross-Over Studies; Double-Blind Method; Female; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Lidocaine; Male; Mouthwashes; Pain; Pain Management; Pain Measurement; Pain Threshold; Tongue; Young Adult

2018
Considerations on the Obstacles That Lead to Slow Recruitment in a Pain Management Clinical Trial: Experiences from the Belgian PELICAN (PrEgabalin Lidocaine Capsaicin Neuropathic Pain) Pragmatic Study.
    Pain research & management, 2023, Volume: 2023

    Topics: Belgium; Capsaicin; Humans; Lidocaine; Neuralgia; Pain Management; Pilot Projects; Pregabalin; Quality of Life

2023

Other Studies

118 other study(ies) available for lidocaine and capsaicin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Study on the dye leakage response of nasal mucosa following topical, capsaicin challenge in guinea pigs.
    Acta oto-laryngologica, 1992, Volume: 112, Issue:3

    Topics: Administration, Intranasal; Administration, Topical; Animals; Atropine; Benzenesulfonates; Capsaicin; Chromones; Coloring Agents; Diphenhydramine; Exudates and Transudates; Guinea Pigs; Histamine; Histamine Release; Injections, Subcutaneous; Lidocaine; Male; Methacholine Chloride; Nasal Mucosa; Nasal Provocation Tests; Substance P

1992
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin.
    The British journal of dermatology, 1992, Volume: 126, Issue:2

    Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation

1992
Mechanism of nasal secretion mediated via nerve reflex in guinea pigs and evaluation of antiallergic drugs.
    International archives of allergy and immunology, 1992, Volume: 97, Issue:2

    Topics: Allergens; Aminopyridines; Animals; Atropine Derivatives; Bronchodilator Agents; Capsaicin; Ganglionic Blockers; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Hypersensitivity; Lidocaine; Methacholine Chloride; Nasal Mucosa; ortho-Aminobenzoates; Parasympatholytics; Phthalazines; Pyrilamine; Reflex

1992
Axon reflex flare evoked by nicotine in human skin.
    The Japanese journal of physiology, 1992, Volume: 42, Issue:5

    Topics: Adult; Axons; Capsaicin; Diphenhydramine; Female; Humans; Injections, Intradermal; Lidocaine; Male; Middle Aged; Nerve Fibers; Nicotine; Receptors, Histamine; Reflex; Regional Blood Flow; Skin; Vasodilation

1992
The mediation of increased duodenal alkaline secretion in response to 10 mM HCl in the anaesthetized rat. Support for the involvement of capsaicin-sensitive nerve elements.
    Acta physiologica Scandinavica, 1992, Volume: 146, Issue:4

    Topics: Animals; Bicarbonates; Capsaicin; Dinoprostone; Duodenum; Hydrochloric Acid; Intestinal Mucosa; Lidocaine; Male; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Vagotomy; Vagus Nerve

1992
Effect of capsaicin on gastric mucosal injury and blood flow following bile acid exposure.
    The Journal of surgical research, 1992, Volume: 52, Issue:6

    Topics: Animals; Bile Acids and Salts; Capsaicin; DNA; Dogs; Gastric Acid; Gastric Mucosa; Lidocaine; Regional Blood Flow

1992
The effect of capsaicin on gallbladder fluid absorption.
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:4 Pt 1

    Topics: Absorption; Animals; Body Fluids; Buffers; Capsaicin; Cats; Gallbladder; Indomethacin; Lidocaine; Osmolar Concentration; Perfusion; Prostaglandins

1991
The mucosal potential elicited by noxious chemical stimuli with CO2 in rats: is it a peripheral nociceptive event?
    Neuroscience letters, 1991, Jul-22, Volume: 128, Issue:2

    Topics: Animals; Capsaicin; Carbon Dioxide; Electroencephalography; Evoked Potentials; Guanethidine; Lidocaine; Male; Nasal Mucosa; Neurons; Nociceptors; Peripheral Nerves; Rats; Rats, Inbred Strains; Stimulation, Chemical; Sympathetic Nervous System; Trigeminal Nerve

1991
Separation of cough and reflex bronchoconstriction by inhaled local anaesthetics.
    The European respiratory journal, 1990, Volume: 3, Issue:5

    Topics: Administration, Inhalation; Adult; Anesthetics, Local; Bronchial Spasm; Capsaicin; Cough; Female; Humans; Lidocaine; Male; Neural Conduction; Propiophenones; Reflex

1990
Capsaicin challenge, reflex bronchoconstriction, and local action of substance P.
    The American journal of physiology, 1988, Volume: 254, Issue:5 Pt 2

    Topics: Aerosols; Airway Resistance; Animals; Atropine; Blood Pressure; Bronchi; Capsaicin; Guinea Pigs; Lidocaine; Plethysmography; Reflex; Substance P; Vagus Nerve

1988
Tachykinins mediate hypocapnia-induced bronchoconstriction in guinea pigs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 67, Issue:6

    Topics: Animals; Bronchi; Bupivacaine; Capsaicin; Carbon Dioxide; Female; Glycopeptides; Guinea Pigs; Lidocaine; Male; Tachykinins

1989
Nonadrenergic bronchodilator mechanisms in normal human subjects in vivo.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 64, Issue:5

    Topics: Adult; Airway Resistance; Bronchi; Bronchodilator Agents; Capsaicin; Cough; Female; Humans; Ipratropium; Lidocaine; Male; Propranolol; SRS-A

1988
Role of vagal and sympathetic afferents in reflex respiratory responses to capsaicin in dogs.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:7

    Topics: Animals; Capsaicin; Dogs; Lidocaine; Neurons, Afferent; Respiration; Spinal Cord; Sympathetic Nervous System; Thoracotomy; Vagotomy; Vagus Nerve

1988
Epicardial application of capsaicin causes tachycardia and pressor effect in guinea pigs.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 57, Issue:1

    Topics: Administration, Topical; Animals; Blood Pressure; Capsaicin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart; Heart Rate; Lidocaine; Male; Vagotomy

1987
Sorbic acid-induced erythema and edema.
    Journal of the American Academy of Dermatology, 1986, Volume: 14, Issue:2 Pt 1

    Topics: Administration, Topical; Anti-Inflammatory Agents; Aspirin; Betamethasone Valerate; Capsaicin; Cosmetics; Dermatitis, Atopic; Dose-Response Relationship, Drug; Edema; Erythema; Fatty Acids, Unsaturated; Histamine; Humans; Hydrocortisone; Hydroxyzine; Lidocaine; Mast Cells; Pharmaceutic Aids; Preservatives, Pharmaceutical; Sorbic Acid

1986
Anti-asthma drugs and capsaicine-induced microvascular effects in lower airways.
    Agents and actions, 1985, Volume: 16, Issue:1-2

    Topics: Animals; Asthma; Bronchodilator Agents; Capillary Permeability; Capsaicin; Guinea Pigs; Lidocaine; Male; Terbutaline; Trachea; Xanthines

1985
Sensitivity of pulmonary chemo reflexes and lung inflation reflexes to repetitive stimulation and to inhibition with lidocaine and morphine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:2-3

    Topics: Animals; Blood Gas Analysis; Capsaicin; Dogs; Female; Hemodynamics; Injections, Intra-Arterial; Lidocaine; Lung; Male; Morphine; Naloxone; Nerve Fibers; Pulmonary Artery; Reflex; Respiration

1985
Capsaicin desensitization inhibits swallowing reflex in guinea pigs.
    American journal of respiratory and critical care medicine, 1994, Volume: 149, Issue:1

    Topics: Acetylcholine; Afferent Pathways; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Deglutition; Dipeptides; Dose-Response Relationship, Drug; Electromyography; Guinea Pigs; Indoles; Lidocaine; Nerve Fibers; Premedication; Reflex; Substance P

1994
The differential mechanisms of mild irritants on adaptive cytoprotection.
    Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1

    Topics: Adaptation, Physiological; Animals; Arginine; Atropine; Capsaicin; Chorionic Gonadotropin; Ethanol; Gastric Mucosa; Hexamethonium; Indomethacin; Irritants; Lidocaine; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach Ulcer; Substance P

1994
[Capsaicin-induced cough. Tachyphylaxis and the effect of anaesthesia on the pharynx].
    Arerugi = [Allergy], 1994, Volume: 43, Issue:12

    Topics: Adult; Anesthesia; Capsaicin; Cough; Female; Humans; Lidocaine; Male; Middle Aged; Pharynx

1994
Potentiation by capsaicin of lidocaine's phasic impulse block in isolated rat sciatic nerve.
    Pharmacological research, 1994, Volume: 30, Issue:1

    Topics: Action Potentials; Animals; Capsaicin; Drug Synergism; In Vitro Techniques; Lidocaine; Male; Nerve Fibers; Nerve Fibers, Myelinated; Rats; Sciatic Nerve

1994
Adrenergic, purinergic, and endothelial mediators and modulators of norepinephrine-induced mesenteric autoregulatory escape.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:8

    Topics: Adenosine Deaminase; Animals; Animals, Newborn; Blood Flow Velocity; Capsaicin; Denervation; Dose-Response Relationship, Drug; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Homeostasis; In Vitro Techniques; Lidocaine; Male; Mesenteric Arteries; Methylene Blue; Norepinephrine; Phentolamine; Portal Pressure; Propranolol; Rats; Rats, Sprague-Dawley; Ultrasonography; Vasoconstriction

1994
Multifactorial mediation of post norepinephrine induced intestinal hyperemia.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:2

    Topics: Adenosine Deaminase; Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Animals; Animals, Newborn; Capsaicin; Denervation; Dose-Response Relationship, Drug; Hexamethonium Compounds; Hyperemia; Intestines; Lidocaine; Male; Methylene Blue; Neurons, Afferent; Norepinephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Splanchnic Circulation; Sympathetic Nervous System

1994
Potentiation by capsaicin of lidocaine's tonic impulse block in isolated rat sciatic nerve.
    Neuroscience letters, 1994, Jun-06, Volume: 174, Issue:1

    Topics: Action Potentials; Animals; Capsaicin; Drug Synergism; Electric Stimulation; In Vitro Techniques; Lidocaine; Male; Nerve Fibers; Nerve Fibers, Myelinated; Neural Conduction; Rats; Sciatic Nerve

1994
The behavioral response induced by intravesical instillation of capsaicin rats is mediated by pudendal urethral sensory fibers.
    Life sciences, 1994, Volume: 55, Issue:6

    Topics: Animals; Behavior, Animal; Capsaicin; Female; Lidocaine; Male; Neurons, Afferent; Rats; Rats, Wistar; Tetrodotoxin; Urethra; Urinary Bladder

1994
Primary sensory nerves mediate in part the protective mesenteric hyperemia after intraduodenal acidification in rats.
    Gastroenterology, 1993, Volume: 105, Issue:6

    Topics: Animals; Capsaicin; Duodenum; Hydrochloric Acid; Hyperemia; Lidocaine; Male; Mesenteric Artery, Superior; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Regional Blood Flow

1993
Sensory neuron-mediated gastric mucosal protection is blocked by cyclooxygenase inhibition.
    Surgery, 1994, Volume: 115, Issue:2

    Topics: Administration, Topical; Animals; Bile Acids and Salts; Capsaicin; Cyclooxygenase Inhibitors; DNA; Gastric Mucosa; Indomethacin; Lidocaine; Nerve Block; Neurons, Afferent; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Taurocholic Acid

1994
Electrocorticographic desynchronization after application of visceral and somatic noxious stimuli in urethane-anesthetized rats: effect of intrathecal administration of tachykinin (NK 1 or NK 2) receptor antagonists.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1

    Topics: Acetylcholine; Administration, Topical; Anesthesia; Animals; Benzamides; Capsaicin; Cortical Synchronization; Electric Stimulation; Indoles; Injections, Spinal; Isoindoles; Lidocaine; Male; Perineum; Physalaemin; Piperidines; Rats; Rats, Wistar; Receptors, Tachykinin; Sensitivity and Specificity; Urethane; Urinary Bladder

1996
[Therapeutic trials with topical capsaicin cream and iontophoretically applied lidocaine for diabetic painful truncal neuropathy].
    Rinsho shinkeigaku = Clinical neurology, 1996, Volume: 36, Issue:1

    Topics: Capsaicin; Diabetic Neuropathies; Humans; Hyperesthesia; Iontophoresis; Lidocaine; Male; Middle Aged; Ointments; Pain

1996
Urodynamic changes during therapeutic intravesical instillations of capsaicin.
    British journal of urology, 1996, Volume: 77, Issue:6

    Topics: Administration, Intravesical; Adolescent; Adult; Aged; Anesthetics, Local; Capsaicin; Female; Humans; Lidocaine; Male; Middle Aged; Muscle Contraction; Pain Measurement; Urinary Incontinence; Urodynamics

1996
Capsaicin-induced rapid receptive field reorganization in cuneate neurons.
    Journal of neurophysiology, 1996, Volume: 75, Issue:3

    Topics: Afferent Pathways; Animals; Capsaicin; Cats; Ganglia, Sensory; Lidocaine; Membrane Potentials; Neurons; Time Factors

1996
Skin blood flow disturbances in the contralateral limb in a peripheral mononeuropathy in the rat.
    Neuroscience, 1996, Volume: 74, Issue:3

    Topics: Animals; Capsaicin; Cold Temperature; Electric Stimulation; Functional Laterality; Hindlimb; Lidocaine; Male; Nerve Fibers; Neurons, Afferent; Pain; Peripheral Nervous System Diseases; Rats; Rats, Inbred Lew; Regional Blood Flow; Sciatic Nerve; Skin; Spinal Cord; Time Factors; Ultrasonography, Doppler; Vasoconstriction; Vasodilation

1996
Role of vagal lung C-fibres in the cardiorespiratory effects of capsaicin in monkeys.
    Respiration physiology, 1996, Volume: 106, Issue:2

    Topics: Administration, Inhalation; Animals; Capsaicin; Cardiovascular System; Cold Temperature; Female; Halothane; Heart; Heart Atria; Injections; Lidocaine; Lung; Macaca mulatta; Male; Nerve Fibers; Pericardium; Respiratory System; Vagotomy; Vagus Nerve

1996
Tetrodotoxin-resistant Na+ spikes of C fibers have at least two subtypes in the isolated bullfrog sciatic nerve.
    Neuroscience letters, 1996, Dec-27, Volume: 221, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Cadmium; Capsaicin; Electric Stimulation; Electrophysiology; Lidocaine; Nerve Fibers; Rana catesbeiana; Sciatic Nerve; Sodium; Tetrodotoxin

1996
Effects of chemical sympathectomy and sensory nerve ablation on experimental colitis in the rat.
    The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 1

    Topics: Administration, Topical; Animals; Capsaicin; Colitis; Colon; Denervation; Female; Injections; Lidocaine; Male; Nervous System; Oxidopamine; Rats; Rats, Sprague-Dawley; Sensation; Sympathectomy, Chemical; Trinitrobenzenesulfonic Acid

1997
Neurogenic inflammation in cholecystitis.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:7

    Topics: Animals; Bradykinin; Capsaicin; Cholecystitis; Gallbladder; Guinea Pigs; Lidocaine; Lipopolysaccharides; Nerve Endings; Nerve Fibers; Nociceptors; Oxidopamine

1997
Positive modulation of pepsinogen secretion by gastric acidity after vagal cholinergic stimulation.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3

    Topics: Animals; Bethanechol; Capsaicin; Electric Stimulation; Gastric Acid; Gastric Acidity Determination; Lidocaine; Male; Pepsinogens; Rats; Rats, Wistar; Vagus Nerve

1997
Electromotive drug administration of lidocaine to anesthetize the bladder before intravesical capsaicin.
    The Journal of urology, 1998, Volume: 159, Issue:6

    Topics: Administration, Intravesical; Adult; Aged; Anesthetics, Local; Capsaicin; Female; Humans; Iontophoresis; Lidocaine; Male; Middle Aged; Reflex, Abnormal; Urinary Bladder Diseases; Urodynamics

1998
Lidocaine prevents noxious excitation of bladder afferents induced by intravesical capsaicin without interfering with the ensuing sensory desensitization: an experimental study in the rat.
    The Journal of urology, 1998, Volume: 159, Issue:2

    Topics: Administration, Intravesical; Anesthetics, Local; Animals; Capsaicin; Female; Lidocaine; Rats; Rats, Wistar; Urinary Bladder

1998
Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig cornea.
    The Journal of physiology, 1998, Oct-01, Volume: 512 ( Pt 1)

    Topics: Animals; Capsaicin; Ciliary Body; Cornea; Electric Stimulation; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Lidocaine; Nerve Endings; Nociceptors; Reaction Time; Sodium Channels; Tetrodotoxin

1998
[Effect of epidural anesthesia on airway constriction induced with methacholine or capsaicin in cats].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:8

    Topics: Action Potentials; Airway Resistance; Anesthesia, Epidural; Anesthetics, Local; Animals; Bronchoconstriction; Bronchoconstrictor Agents; Capsaicin; Cats; Heart; Lidocaine; Methacholine Chloride; Sympathetic Nervous System; Vagus Nerve

1998
Physiological oxygen concentration gives an oscillating spontaneous tone in guinea-pig tracheal preparations.
    Acta physiologica Scandinavica, 1999, Volume: 165, Issue:1

    Topics: Animals; Capsaicin; Electric Stimulation; Guinea Pigs; Heptanol; In Vitro Techniques; Indomethacin; Lidocaine; Male; Muscle Tonus; Muscle, Smooth; Oscillometry; Oxygen; Tetrodotoxin; Trachea

1999
The inflammatory reaction induced by formalin in the rat paw.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:3

    Topics: Anesthetics, Local; Animals; Blood Pressure; Bradykinin; Capillary Permeability; Capsaicin; Dose-Response Relationship, Drug; Edema; Extravasation of Diagnostic and Therapeutic Materials; Formaldehyde; Inflammation; Inflammation Mediators; Kininogens; Lidocaine; Male; Neuropeptides; Rats; Rats, Wistar; Serum Albumin; Time Factors

1999
Urethral afferent nerve activity affects the micturition reflex; implication for the relationship between stress incontinence and detrusor instability.
    The Journal of urology, 1999, Volume: 162, Issue:1

    Topics: Anesthetics, Local; Animals; Capsaicin; Enzyme Inhibitors; Female; Lidocaine; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Reflex, Abnormal; Sodium Chloride; Urethra; Urinary Bladder; Urinary Incontinence, Stress; Urination

1999
CCK1 and CCK2 receptors regulate gastric pepsinogen secretion.
    European journal of pharmacology, 1999, May-28, Volume: 373, Issue:1

    Topics: Acids; Anesthetics, Local; Animals; Benzodiazepinones; Capsaicin; Devazepide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Acid; Gastric Mucosa; Gastrins; Histidine Decarboxylase; Hormone Antagonists; Lidocaine; Male; Methylhistidines; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nootropic Agents; Omeprazole; Pepsinogens; Perfusion; Phenylurea Compounds; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide; Somatostatin; Vagotomy

1999
Acid-sensitive and alkaline-sensitive sensory neurons regulate pH dependent gastrin secretion in rat.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:6

    Topics: Acids; Alkalies; Anesthetics, Local; Animals; Capsaicin; Gastrins; Hydrogen; Hydrogen-Ion Concentration; Lidocaine; Male; Neurons, Afferent; Pyloric Antrum; Rats; Rats, Wistar; RNA, Messenger; Somatostatin

2000
Effects of perineural capsaicin treatment on cardiopulmonary reflexes elicited by laryngeal instillations of capsaicin and distilled water in sevoflurane-anesthetized dogs.
    The Journal of veterinary medical science, 2000, Volume: 62, Issue:6

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Capsaicin; Dogs; Female; Heart Rate; Laryngeal Masks; Laryngeal Nerves; Larynx; Lidocaine; Male; Methyl Ethers; Reflex; Respiration; Respiratory Function Tests; Sevoflurane; Water

2000
Influence of bronchial C fibre receptors on respiration in cats: possible role in humans.
    Respiration physiology, 2000, Volume: 123, Issue:1-2

    Topics: Anesthetics, Local; Animals; Atrial Function; Biguanides; Blood Pressure; Bronchi; Bronchial Arteries; Capsaicin; Cats; Heart Rate; Hemodynamics; Humans; Injections; Lidocaine; Nerve Fibers; Respiratory Mechanics; Serotonin Receptor Agonists; Vagotomy

2000
Respiratory and cardiovascular reflexes elicited by nasal instillation of capsaicin to anesthetized, spontaneously breathing dogs.
    The Journal of veterinary medical science, 2001, Volume: 63, Issue:4

    Topics: Administration, Intranasal; Anesthetics, Local; Animals; Apnea; Blood Pressure; Bronchoconstriction; Capsaicin; Cardiovascular Physiological Phenomena; Dogs; Female; Heart Rate; Lidocaine; Male; Nasal Cavity; Reflex; Respiration; Respiratory Function Tests

2001
Hot chili, a cook and EMLA.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:6

    Topics: Anesthetics, Local; Capsaicin; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Prilocaine

2001
Blood flow changes in human dental pulps when capsaicin is applied to the adjacent gingival mucosa.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2001, Volume: 92, Issue:5

    Topics: Adult; Anesthetics, Local; Axons; Capsaicin; Cuspid; Dental Pulp; Female; Gingiva; Humans; Laser-Doppler Flowmetry; Lidocaine; Male; Mandibular Nerve; Mouth Mucosa; Nerve Block; Neurons, Afferent; Prilocaine; Regional Blood Flow; Sensory System Agents; Vasodilation

2001
A human oral capsaicin pain model to assess topical anesthetic-analgesic drugs.
    Neuroscience letters, 2001, Dec-28, Volume: 316, Issue:3

    Topics: Administration, Topical; Adult; Anesthetics, Local; Capsaicin; Female; Genetic Variation; Humans; Lidocaine; Male; Models, Neurological; Nociceptors; Pain; Pain Measurement; Tongue

2001
The relationship between propagated contractions and pseudoaffective changes in blood pressure in response to intestinal distension.
    Neurogastroenterology and motility, 2001, Volume: 13, Issue:6

    Topics: Adrenergic alpha-Antagonists; Affect; Anesthetics, Local; Animals; Blood Pressure; Capsaicin; Heart Rate; Intestines; Lidocaine; Mesentery; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicotinic Antagonists; Pain; Physical Stimulation; Pressure; Rats; Rats, Sprague-Dawley; Reflex

2001
Central AT1 receptors are involved in the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure.
    Basic research in cardiology, 2002, Volume: 97, Issue:4

    Topics: Anesthetics, Local; Angiotensin II; Animals; Anti-Arrhythmia Agents; Bradykinin; Capsaicin; Heart Failure; Heart Ventricles; Hemodynamics; Injections, Intravenous; Injections, Intraventricular; Lidocaine; Ligation; Losartan; Male; Myocardial Infarction; Myocardium; Neurons, Afferent; Organ Size; Pericardium; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reflex; Renin; Sympathetic Nervous System; Ventricular Function

2002
A role for abdominal vagal afferents in lipopolysaccharide-induced hypotension.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:2

    Topics: Animals; Blood Pressure Determination; Capsaicin; Disease Models, Animal; Drug Interactions; Female; Hypotension; Injections, Intravenous; Leukocyte Count; Lidocaine; Lipopolysaccharides; Nerve Block; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity; Shock, Septic; Vagus Nerve

2002
Role of voltage-gated cation channels and axon reflexes in the release of sensory neuropeptides by capsaicin from isolated rat trachea.
    European journal of pharmacology, 2003, Jan-05, Volume: 458, Issue:3

    Topics: Agatoxins; Anesthetics, Local; Animals; Axons; Cadmium; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Lidocaine; Male; Neuropeptides; omega-Conotoxin GVIA; Rats; Reflex; Sodium Channels; Somatostatin; Spider Venoms; Substance P; Tetrodotoxin; Trachea

2003
RSD931, a novel anti-tussive agent acting on airway sensory nerves.
    British journal of pharmacology, 2003, Volume: 138, Issue:3

    Topics: Administration, Inhalation; Aerosols; Animals; Antitussive Agents; Bronchi; Bronchoconstriction; Capsaicin; Carnosine; Citric Acid; Cough; Dose-Response Relationship, Drug; Female; Guinea Pigs; Lidocaine; Lung; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Rabbits; Time Factors

2003
THE R OLE OF THE VESICAL MUCOSA IN REFLEX MICTURITION.
    British journal of urology, 1965, Volume: 37

    Topics: Animals; Capsaicin; Capsicum; Cocaine; Dogs; Lidocaine; Mucous Membrane; Nerve Endings; Pharmacology; Reflex; Research; Urinary Bladder; Urination

1965
Neurokinin release produced by capsaicin acting on the central terminals and axons of primary afferents: relationship with N-methyl-D-aspartate and GABA(B) receptors.
    Neuroscience, 2003, Volume: 121, Issue:3

    Topics: Afferent Pathways; Analysis of Variance; Anesthetics, Local; Animals; Axons; Baclofen; Calcium; Capsaicin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Functional Laterality; GABA Agonists; Immunohistochemistry; In Vitro Techniques; Indoles; Isoindoles; Lidocaine; Microscopy, Confocal; Neurokinin-1 Receptor Antagonists; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Spinal Nerve Roots; Time Factors

2003
An assessment of vascular pain using the flexor reflex in anesthetized rats.
    Methods and findings in experimental and clinical pharmacology, 2004, Volume: 26, Issue:2

    Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Electromyography; Hindlimb; Injections, Intra-Arterial; Injections, Spinal; Injections, Subcutaneous; Lidocaine; Male; Morphine; Muscle, Skeletal; Naloxone; Pain Measurement; Procaine; Rats; Rats, Sprague-Dawley; Reflex, Stretch; Time Factors; Toes; Vascular Diseases

2004
Occlusion of dentinal tubules and selective block of pulp innervation prevent the nociceptive behaviour induced in rats by intradental application of irritants.
    Archives of oral biology, 2004, Volume: 49, Issue:6

    Topics: Anesthetics, Local; Animals; Capsaicin; Dental Pulp; Female; Incisor; Irritants; Lidocaine; Male; Models, Animal; Nerve Block; Neurons, Afferent; Nociceptors; Oxalates; Rats; Rats, Sprague-Dawley; Receptors, Drug

2004
Current source density analysis of laser heat-evoked intra-cortical field potentials in the primary somatosensory cortex of rats.
    Neuroscience, 2006, Jul-21, Volume: 140, Issue:4

    Topics: Animals; Capsaicin; Electric Stimulation; Evoked Potentials, Somatosensory; Hot Temperature; Lasers; Lidocaine; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Somatosensory Cortex; Stimulation, Chemical

2006
Developmental changes in threshold, conduction velocity, and depressive action of lignocaine on dorsal root potentials from neonatal rats are associated with maturation of myelination.
    Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:2

    Topics: Anesthetics, Local; Animals; Animals, Newborn; Capsaicin; Ethanol; Female; Lidocaine; Male; Myelin Sheath; Nerve Fibers, Myelinated; Neural Conduction; Rats; Rats, Sprague-Dawley; Spinal Nerve Roots

2007
A role for peripheral afferents in the pathophysiology and treatment of at-level neuropathic pain in spinal cord injury? A case report.
    Pain, 2007, Volume: 131, Issue:1-2

    Topics: Administration, Topical; Afferent Pathways; Capsaicin; Humans; Hyperalgesia; Lidocaine; Male; Middle Aged; Spinal Fractures; Thoracic Vertebrae

2007
Organ cross talk modulates pelvic pain.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:3

    Topics: Anesthetics, Local; Animals; Behavior, Animal; Capsaicin; Colon; Cystitis, Interstitial; Evans Blue; Female; Herpesvirus 1, Suid; Lidocaine; Mice; Mice, Inbred C57BL; Pelvic Pain; Physical Stimulation; Pseudorabies; Viral Plaque Assay

2007
Neuroscience: a local route to pain relief.
    Nature, 2007, Oct-04, Volume: 449, Issue:7162

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Capsaicin; Cell Membrane Permeability; Electric Conductivity; Humans; Lidocaine; Nociceptors; Pain; Sodium; Sodium Channel Blockers; TRPV Cation Channels

2007
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
    Nature, 2007, Oct-04, Volume: 449, Issue:7162

    Topics: Anesthesia, Local; Anesthetics, Local; Animals; Capsaicin; Cell Membrane Permeability; Electric Conductivity; Ganglia, Spinal; Lidocaine; Neurons; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; TRPV Cation Channels

2007
Chillies: out of the frying pan and into the clinic?
    Lancet (London, England), 2007, Oct-13, Volume: 370, Issue:9595

    Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Capsaicin; Drug Interactions; Humans; Lidocaine; Pain; Rats; TRPV Cation Channels

2007
The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:2

    Topics: Anesthetics, Local; Animals; Ankyrins; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Cell Line; Evoked Potentials; Humans; Lidocaine; Neurons, Afferent; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sensory System Agents; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels

2008
Paraventricular nucleus is involved in the central pathway of cardiac sympathetic afferent reflex in rats.
    Experimental physiology, 2008, Volume: 93, Issue:6

    Topics: Afferent Pathways; Anesthetics, Local; Animals; Blood Pressure; Bradykinin; Capsaicin; Central Nervous System; Excitatory Amino Acid Agonists; Glutamic Acid; Heart; Kainic Acid; Lidocaine; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System

2008
Continued inhalation of lidocaine suppresses antigen-induced airway hyperreactivity and airway inflammation in ovalbumin-sensitized guinea pigs.
    International immunopharmacology, 2008, Volume: 8, Issue:5

    Topics: Administration, Inhalation; Anesthetics, Local; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsaicin; Cell Count; Cough; Eosinophils; Guinea Pigs; Histamine; Inflammation; Lidocaine; Lung; Male; Ovalbumin; Substance P

2008
NK-1 receptors in the rostral ventromedial medulla contribute to hyperalgesia produced by intraplantar injection of capsaicin.
    Pain, 2008, Sep-30, Volume: 139, Issue:1

    Topics: Animals; Capsaicin; Hindlimb; Hyperalgesia; Lidocaine; Male; Medulla Oblongata; Microinjections; Neurokinin-1 Receptor Antagonists; Pain Measurement; Pilot Projects; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1

2008
Surgical incision can alter capsaicin-induced central sensitization in rat brainstem nociceptive neurons.
    Neuroscience, 2008, Oct-15, Volume: 156, Issue:3

    Topics: Action Potentials; Analysis of Variance; Anesthetics, Local; Animals; Capsaicin; Hyperalgesia; Lidocaine; Male; Mechanoreceptors; Nociceptors; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Skin; Temporomandibular Joint; Trigeminal Nucleus, Spinal

2008
Nociceptive vascular reflexes evoked by scorpion venom modulate cardiorespiratory parameters involving vanilloid receptor 1 in anaesthetised rats.
    Neuroscience letters, 2009, Feb-27, Volume: 451, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Blood Vessels; Capsaicin; Cardiovascular Physiological Phenomena; Drug Interactions; Heart Rate; Injections, Intra-Arterial; Lidocaine; Male; Nociceptors; Rats; Receptors, Serotonin, 5-HT3; Reflex; Respiratory Physiological Phenomena; Scorpion Venoms; Sensory Receptor Cells; Serotonin; Time Factors; TRPV Cation Channels; Visceral Afferents

2009
Increased phosphorylation of extracellular signal-regulated kinase in trigeminal nociceptive neurons following propofol administration in rats.
    The journal of pain, 2009, Volume: 10, Issue:6

    Topics: Anesthetics, Local; Animals; Brain; Capsaicin; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Hypnotics and Sedatives; Lidocaine; Male; Nociceptors; Pentobarbital; Phosphorylation; Propofol; Rats; Rats, Sprague-Dawley; Sensory System Agents; Spinal Cord; Trigeminal Nerve

2009
Urodynamic effects of the bladder C-fiber afferent activity modulation in chronic model of overactive bladder in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60, Issue:4

    Topics: Administration, Intravesical; Afferent Pathways; Anesthetics, Local; Animals; Capsaicin; Cystitis; Disease Models, Animal; Female; Lidocaine; Nerve Fibers, Unmyelinated; Random Allocation; Rats; Rats, Wistar; Sensory System Agents; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urodynamics

2009
Selectively targeting pain in the trigeminal system.
    Pain, 2010, Volume: 150, Issue:1

    Topics: Action Potentials; Analysis of Variance; Anesthetics, Local; Animals; Capsaicin; Electric Stimulation; Lidocaine; Mice; Mice, Knockout; Neurons; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Reflex; Trigeminal Ganglion; TRPV Cation Channels

2010
[Types of topical treatment for peripheral neuropathic pain : Mechanism of action and indications].
    Schmerz (Berlin, Germany), 2010, Volume: 24, Issue:4

    Topics: Administration, Topical; Afferent Pathways; Analgesics; Anesthetics, Local; Antidepressive Agents; Capsaicin; Humans; Lidocaine; Nerve Fibers; Nerve Regeneration; Neuralgia; Peripheral Nervous System Diseases; Sensory System Agents; TRPV Cation Channels

2010
Luminal serotonin time-dependently modulates vagal afferent driven antinociception in response to colorectal distention in rats.
    Neurogastroenterology and motility, 2011, Volume: 23, Issue:1

    Topics: Afferent Pathways; Analgesics; Animals; Capsaicin; Colon; Dilatation, Pathologic; Food Hypersensitivity; Granisetron; Hyperalgesia; Intestinal Mucosa; Lidocaine; Male; Pain; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Time Factors; Vagotomy; Vagus Nerve

2011
Bring on the heat: transient receptor potential vanilloid type-1 (TRPV-1) channels as a sensory link for local thermal hyperaemia.
    The Journal of physiology, 2010, Nov-01, Volume: 588, Issue:Pt 21

    Topics: Anesthetics, Local; Capsaicin; Hot Temperature; Humans; Hyperemia; Lidocaine; Lidocaine, Prilocaine Drug Combination; Nitric Oxide; Prilocaine; Regional Blood Flow; Sensory Receptor Cells; Skin; TRPV Cation Channels

2010
Peripheral nerve injury and TRPV1-expressing primary afferent C-fibers cause opening of the blood-brain barrier.
    Molecular pain, 2010, Nov-02, Volume: 6

    Topics: Animals; Blood-Brain Barrier; Capsaicin; Constriction, Pathologic; Lidocaine; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurons, Afferent; Permeability; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Time Factors; TRPV Cation Channels

2010
Pharmaceutical therapy for radiculopathy.
    Physical medicine and rehabilitation clinics of North America, 2011, Volume: 22, Issue:1

    Topics: Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Capsaicin; Humans; Lidocaine; Muscle Relaxants, Central; Radiculopathy; Tumor Necrosis Factor-alpha

2011
Characterization of dental nociceptive neurons.
    Journal of dental research, 2011, Volume: 90, Issue:6

    Topics: Action Potentials; Anesthetics, Local; Animals; Capsaicin; Cells, Cultured; Fluorescent Dyes; Lidocaine; NAV1.8 Voltage-Gated Sodium Channel; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Reverse Transcriptase Polymerase Chain Reaction; Sensory System Agents; Sodium Channel Blockers; Sodium Channels; Tooth; Toothache; Transient Receptor Potential Channels; Trigeminal Ganglion

2011
Rostroventral medulla-mediated biphasic modulation of the rat cardiosomatic motor reflex.
    Neuroscience, 2011, Jun-30, Volume: 185

    Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthetics, Local; Animals; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Functional Laterality; Lidocaine; Male; Medulla Oblongata; Naloxone; Narcotic Antagonists; Neural Pathways; Rats; Rats, Sprague-Dawley; Reflex; Sensory System Agents; Spinal Cord Injuries; Yohimbine

2011
Intractable neuropathic pain in spinal intramedullary cavernoma treated successfully with a novel combination cream.
    Pain medicine (Malden, Mass.), 2012, Volume: 13, Issue:5

    Topics: Capsaicin; Drug Combinations; Humans; Isosorbide Dinitrate; Lidocaine; Male; Middle Aged; Neuralgia; Ointments; Pain, Intractable; Spinal Cord Neoplasms

2012
Involvement of enhanced cardiac sympathetic afferent reflex in sympathetic activation in early stage of diabetes.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 113, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Bradykinin; Capsaicin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diterpenes; Heart; Kidney; Lidocaine; Losartan; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Sympathetic Nervous System; TRPV Cation Channels

2012
Differential effects of peripheral versus central coadministration of QX-314 and capsaicin on neuropathic pain in rats.
    Anesthesiology, 2012, Volume: 117, Issue:2

    Topics: Anesthetics, Local; Animals; Antipruritics; Capsaicin; Disease Models, Animal; Drug Administration Routes; Drug Therapy, Combination; Hyperalgesia; Lidocaine; Male; Neuralgia; Peripheral Nerves; Rats; Rats, Sprague-Dawley

2012
Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes.
    Molecular pharmacology, 2012, Volume: 82, Issue:6

    Topics: Anesthetics, Local; Animals; Benzocaine; Capsaicin; Lidocaine; Mutation; Oocytes; Quaternary Ammonium Compounds; Tetraethylammonium; TRPV Cation Channels; Xenopus laevis; Xenopus Proteins

2012
Expression of TRPV1 channels after nerve injury provides an essential delivery tool for neuropathic pain attenuation.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Anesthetics, Local; Animals; Capsaicin; Gene Expression; Hyperalgesia; Lidocaine; Male; Mandibular Nerve; Myelin Sheath; Nerve Regeneration; Neuralgia; Nociceptors; Pain Management; Pain Threshold; Rats; Rats, Sprague-Dawley; Trigeminal Ganglion; Trigeminal Nerve Injuries; TRPV Cation Channels

2012
Enhanced adipose afferent reflex contributes to sympathetic activation in diet-induced obesity hypertension.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:5

    Topics: Adipose Tissue, White; Angiotensin II; Animals; Blood Pressure; Capsaicin; Diet, High-Fat; Diterpenes; Enzyme-Linked Immunosorbent Assay; Hypertension; Immunohistochemistry; Lidocaine; Male; Norepinephrine; Obesity; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reflex; Renin; Sensory System Agents; Sympathetic Nervous System

2012
Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Jan-02, Volume: 33, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Axons; Behavior, Animal; Capsaicin; Chronic Pain; Disease Models, Animal; Lidocaine; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sensory Receptor Cells; TRPV Cation Channels

2013
Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314.
    Journal of neurophysiology, 2013, Volume: 109, Issue:7

    Topics: Action Potentials; Animals; Capsaicin; Cell Line, Tumor; Cesium; Connexins; Ganglia, Spinal; Humans; Ion Transport; Lidocaine; Rats; Rats, Sprague-Dawley; Sodium; TRPV Cation Channels

2013
TRPA1 insensitivity of human sural nerve axons after exposure to lidocaine.
    Pain, 2013, Volume: 154, Issue:9

    Topics: Action Potentials; Anesthetics, Local; Animals; Axons; Biophysics; Calcium Channels; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Lidocaine; Mustard Plant; Nerve Fibers; Nerve Tissue Proteins; Neural Conduction; Neurons, Afferent; Plant Oils; Rats; Rats, Wistar; Sural Nerve; Transient Receptor Potential Channels; TRPA1 Cation Channel

2013
Pain fiber anesthetic reduces brainstem Fos after tooth extraction.
    Journal of dental research, 2013, Volume: 92, Issue:11

    Topics: Anesthetics, Combined; Anesthetics, Local; Animals; Brain Stem; Capsaicin; Dental Pulp; Electric Stimulation; Electromyography; Lidocaine; Male; Mandibular Nerve; Masticatory Muscles; Molar; Neural Pathways; Neurons, Afferent; Nociceptors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reflex; Sensory System Agents; Time Factors; Tooth Extraction; Trigeminal Caudal Nucleus

2013
Expectation requires treatment to boost pain relief: an fMRI study.
    Pain, 2014, Volume: 155, Issue:1

    Topics: Adult; Anesthetics, Local; Antipruritics; Brain; Capsaicin; Female; Humans; Image Processing, Computer-Assisted; Lidocaine; Male; Motivation; Oxygen; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Prilocaine; Skin; Time Factors; Young Adult

2014
Treatment of neuropathic pain with the capsaicin 8% patch: is pretreatment with lidocaine necessary?
    Pain practice : the official journal of World Institute of Pain, 2014, Volume: 14, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Dipyrone; Female; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Pain Measurement; Pirinitramide; Time Factors; Transdermal Patch; Treatment Outcome

2014
Capsaicin-sensitive cough receptors in lower airway are responsible for cough hypersensitivity in patients with upper airway cough syndrome.
    Medical science monitor : international medical journal of experimental and clinical research, 2013, Dec-03, Volume: 19

    Topics: Adult; Anesthetics, Local; Capsaicin; Case-Control Studies; Cough; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Histamine; Humans; Hypersensitivity; Hypopharynx; Lidocaine; Male; Middle Aged; Receptors, Calcitonin Gene-Related Peptide; Sputum; Statistics, Nonparametric; TRPV Cation Channels

2013
Nociceptor-selective peripheral nerve block induces delayed mechanical hypersensitivity and neurotoxicity in rats.
    Anesthesiology, 2014, Volume: 120, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Local; Animals; Behavior, Animal; Capsaicin; Disease Models, Animal; Hyperalgesia; Hypersensitivity, Delayed; Lidocaine; Male; Nerve Block; Nerve Fibers; Neural Conduction; Neurotoxicity Syndromes; Nociceptors; Pain, Postoperative; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sensory System Agents; TRPV Cation Channels

2014
External QX-314 inhibits evoked cranial primary afferent synaptic transmission independent of TRPV1.
    Journal of neurophysiology, 2014, Dec-01, Volume: 112, Issue:11

    Topics: Anesthetics, Local; Animals; Capsaicin; Cranial Nerves; Excitatory Postsynaptic Potentials; Lidocaine; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Reaction Time; TRPV Cation Channels

2014
Expectations and positive emotional feelings accompany reductions in ongoing and evoked neuropathic pain following placebo interventions.
    Pain, 2014, Volume: 155, Issue:12

    Topics: Adult; Aged; Anesthetics, Local; Capsaicin; Emotions; Female; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Nocebo Effect; Pain Measurement; Physical Stimulation; Placebo Effect; Postoperative Complications; Psychological Tests; Sensory System Agents; Thoracostomy

2014
Distinct neural representations of placebo and nocebo effects.
    NeuroImage, 2015, May-15, Volume: 112

    Topics: Adult; Anesthetics, Local; Capsaicin; Cerebral Cortex; Female; Hot Temperature; Humans; Lidocaine; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System; Nocebo Effect; Pain; Pain Perception; Periaqueductal Gray; Placebo Effect; Reward; Set, Psychology; Young Adult

2015
Photoswitchable fatty acids enable optical control of TRPV1.
    Nature communications, 2015, May-22, Volume: 6

    Topics: Animals; Azo Compounds; Bradykinin; Capsaicin; Fatty Acids; Ganglia, Spinal; HEK293 Cells; Humans; In Vitro Techniques; Lidocaine; Lipid Metabolism; Mice; Photochemical Processes; Photochemistry; Serotonin; TRPV Cation Channels

2015
Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
    Neuron, 2015, Jul-15, Volume: 87, Issue:2

    Topics: Airway Remodeling; Anesthetics, Local; Animals; Animals, Newborn; Capsaicin; Cytokines; Disease Models, Animal; Freund's Adjuvant; Green Fluorescent Proteins; Interleukin-5; Lidocaine; Mice; Nociceptors; Ovalbumin; Respiratory Hypersensitivity; Time Factors; Vasoactive Intestinal Peptide

2015
[Shingles symptoms are gone but not the pain].
    MMW Fortschritte der Medizin, 2015, Jul-23, Volume: 157, Issue:13

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Amines; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclohexanecarboxylic Acids; Dipyrone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Guideline Adherence; Humans; Ibuprofen; Lidocaine; Neuralgia, Postherpetic; Phenols; Pregabalin; Tapentadol; Treatment Failure

2015
Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade.
    Nature medicine, 2015, Volume: 21, Issue:11

    Topics: Adult; Aged; Anesthetics, Local; Animals; Antineoplastic Agents; Capsaicin; Diabetic Neuropathies; Female; Flagellin; Ganglia, Spinal; Humans; Hyperalgesia; Lidocaine; Male; Mice; Mice, Knockout; Middle Aged; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neuralgia; Neurofilament Proteins; Neurons; Paclitaxel; Peripheral Nerve Injuries; Sensory System Agents; Toll-Like Receptor 5

2015
[Topical ambroxol for the treatment of neuropathic pain: A first clinical observation. German version].
    Schmerz (Berlin, Germany), 2015, Volume: 29, Issue:6

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Ambroxol; Capsaicin; Female; Humans; Lidocaine; Long-Term Care; Male; Middle Aged; Neuralgia; Pain Measurement; Pain, Postoperative; Retrospective Studies

2015
Supraspinal modulation of neuronal synchronization by nociceptive stimulation induces an enduring reorganization of dorsal horn neuronal connectivity.
    The Journal of physiology, 2018, 05-01, Volume: 596, Issue:9

    Topics: Anesthetics, Local; Animals; Capsaicin; Cats; Female; Hyperalgesia; Lidocaine; Male; Nerve Net; Nociception; Physical Stimulation; Posterior Horn Cells; Sensory System Agents

2018
Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models.
    Pain, 2018, Volume: 159, Issue:6

    Topics: Adult; Aged; Algorithms; Capsaicin; Female; Healthy Volunteers; Humans; Hyperalgesia; Lidocaine; Male; Middle Aged; Models, Biological; Nerve Block; Neuralgia; Pain Measurement; Pain Perception; Pain Threshold; Phenotype; Sensation; Sensory System Agents; Young Adult

2018
[Postherpetic neuralgia of the left trigeminus nerve V1 : Successful therapy with capsaicin 8% patch].
    Schmerz (Berlin, Germany), 2018, Volume: 32, Issue:6

    Topics: Aged; Capsaicin; Humans; Lidocaine; Neuralgia, Postherpetic; Quality of Life; Trigeminal Nerve

2018
Comparison of antinociceptive effects of plain lidocaine versus lidocaine complexed with hydroxypropyl-β-cyclodextrin in animal models of acute and persistent orofacial pain.
    Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:5

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Analgesics; Animals; Capsaicin; Carrageenan; Disease Models, Animal; Formaldehyde; Hot Temperature; Hyperalgesia; Lidocaine; Male; Pain; Rats, Wistar

2019
Lidocaine, a Non-selective Inhibitor of Voltage-Gated Sodium Channels, Blocks Chemically-Induced Cough in Awake Naïve Guinea Pigs.
    Advances in experimental medicine and biology, 2019, Volume: 1160

    Topics: Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Cough; Guinea Pigs; Lidocaine; Voltage-Gated Sodium Channels; Wakefulness

2019
QX-314 inhibits acid-induced activation of esophageal nociceptive C fiber neurons.
    Neurogastroenterology and motility, 2019, Volume: 31, Issue:4

    Topics: Acrylamides; Action Potentials; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Esophagus; Guinea Pigs; Hydrochloric Acid; Lidocaine; Nerve Fibers, Unmyelinated; Nociception; Patch-Clamp Techniques; TRPV Cation Channels

2019
Neuropeptide Y release in the rat spinal cord measured with Y1 receptor internalization is increased after nerve injury.
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Calcium Channel Blockers; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Excitatory Amino Acid Antagonists; Hyperalgesia; Indoles; Interneurons; Lidocaine; Male; Microscopy, Confocal; Neuropeptide Y; Nociception; omega-Conotoxins; Peripheral Nerve Injuries; Posterior Horn Cells; Potassium Chloride; Protein Transport; Protein Tyrosine Phosphatases; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide Y; Sensory System Agents; Spinal Cord; Spinal Nerve Roots; TRPV Cation Channels; Voltage-Gated Sodium Channel Blockers

2019
[Long-term effectiveness of topical analgesics].
    Schmerz (Berlin, Germany), 2020, Volume: 34, Issue:1

    Topics: Administration, Topical; Analgesics; Botulinum Toxins, Type A; Capsaicin; Female; Humans; Lidocaine; Male; Neuralgia

2020
Using transdermal patches to treat neuropathic pain.
    Nursing, 2020, Volume: 50, Issue:4

    Topics: Anesthetics, Local; Capsaicin; Humans; Lidocaine; Neuralgia; Patient Education as Topic; Transdermal Patch

2020