lidocaine and baclofen

lidocaine has been researched along with baclofen in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's7 (35.00)18.2507
2000's6 (30.00)29.6817
2010's3 (15.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andrade, R1
Henry, JL; Hong, Y1
Gilbert, CD; Hirsch, JA1
Foong, FW; Satoh, M1
Fukuda, H; Kudo, Y; Ono, H1
Ono, H1
Berger, TW; Grace, AA; Nisenbaum, ES1
Matsuoka, H; Mizoguchi, K; Nishimura, Y; Obi, T; Takatsu, M1
Aston-Jones, G; Chiang, C1
Johnson, SW; Shen, KZ; Wu, YN1
Clements, JD; Silver, RA1
Lao, LJ; Marvizón, JC; Song, B1
Burnett, A; Cook, IJ; Fuentealba, SE; Szczesniak, MM1
Grothe, B; Koch, U; Magnusson, AK; Park, TJ; Pecka, M1

Reviews

1 review(s) available for lidocaine and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for lidocaine and baclofen

ArticleYear
Differential relaxation and contractile responses of the human upper esophageal sphincter mediated by interplay of mucosal and deep mechanoreceptor activation.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 294, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adult; Anesthetics, Local; Baclofen; Catheterization; Chemoreceptor Cells; Esophageal Sphincter, Upper; Female; GABA Agonists; Humans; Hydrochloric Acid; Infusions, Parenteral; Insufflation; Lidocaine; Male; Mechanoreceptors; Mechanotransduction, Cellular; Middle Aged; Mucous Membrane; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Peristalsis; Pressure; Reflex

2008

Other Studies

18 other study(ies) available for lidocaine and baclofen

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Blockade of neurotransmitter-activated K+ conductance by QX-314 in the rat hippocampus.
    European journal of pharmacology, 1991, Jun-25, Volume: 199, Issue:2

    Topics: Animals; Baclofen; Calcium; Hippocampus; Lidocaine; Membrane Potentials; Norepinephrine; Potassium Channels; Rats; Receptors, GABA-A; Receptors, Serotonin; Serotonin

1991
Phaclofen-reversible effects of GABA in the spinal cord of the rat.
    European journal of pharmacology, 1991, Aug-29, Volume: 201, Issue:2-3

    Topics: Animals; Baclofen; Bicuculline; Blood Pressure; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Injections, Spinal; Lidocaine; Male; Rats; Rats, Inbred Strains; Spinal Cord; Stereoisomerism; Sympathetic Nervous System

1991
Synaptic physiology of horizontal connections in the cat's visual cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Bicuculline; Cats; Electric Stimulation; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Lidocaine; Receptors, GABA-A; Synapses; Visual Cortex

1991
Analgesic potencies of non-narcotic, narcotic and anesthetic drugs as determined by the bradykinin-induced biting-like responses in rats.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Anesthetics; Animals; Baclofen; Bradykinin; Chloralose; Dose-Response Relationship, Drug; Indomethacin; Lidocaine; Male; Morphine; Nociceptors; Rats; Rats, Inbred Strains

1983
Mechanisms of depressant action of muscle relaxants on spinal reflexes: participation of membrane stabilizing action.
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:3

    Topics: Action Potentials; Animals; Baclofen; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Mephenesin; Motor Neurons; Muscle Relaxants, Central; Neuromuscular Junction; Neurons, Afferent; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Tolperisone

1984
Animal techniques for evaluating muscle relaxants.
    Electroencephalography and clinical neurophysiology. Supplement, 1982, Volume: 36

    Topics: Action Potentials; Afferent Pathways; Anesthetics, Local; Animals; Baclofen; Decerebrate State; Lidocaine; Mephenesin; Muscle Relaxants, Central; Muscles; Rats; Reflex; Spinal Cord

1982
Depression of glutamatergic and GABAergic synaptic responses in striatal spiny neurons by stimulation of presynaptic GABAB receptors.
    Synapse (New York, N.Y.), 1993, Volume: 14, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Corpus Striatum; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Lidocaine; Male; Neurons; Pregnanolone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Sodium Channel Blockers; Synapses

1993
Muscle cramp as the result of impaired GABA function--an electrophysiological and pharmacological observation.
    Muscle & nerve, 1993, Volume: 16, Issue:11

    Topics: Amyotrophic Lateral Sclerosis; Baclofen; Clomipramine; Diazepam; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Levodopa; Lidocaine; Male; Middle Aged; Motor Neurons; Muscle Cramp; Muscular Atrophy, Spinal; Nerve Block; Neural Conduction; Sensory Thresholds; Ulnar Nerve

1993
Response of locus coeruleus neurons to footshock stimulation is mediated by neurons in the rostral ventral medulla.
    Neuroscience, 1993, Volume: 53, Issue:3

    Topics: Animals; Baclofen; Basal Ganglia; Cadmium; Electroshock; gamma-Aminobutyric Acid; Lidocaine; Locus Coeruleus; Male; Manganese; Medulla Oblongata; Microinjections; Neurons; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Synapses

1993
Presynaptic inhibition preferentially reduces in NMDA receptor-mediated component of transmission in rat midbrain dopamine neurons.
    British journal of pharmacology, 1999, Volume: 127, Issue:6

    Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Cesium; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Agonists; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Mesencephalon; N-Methylaspartate; Neurons; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

1999
Unveiling synaptic plasticity: a new graphical and analytical approach.
    Trends in neurosciences, 2000, Volume: 23, Issue:3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Baclofen; Cells, Cultured; Computer Graphics; Data Display; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; Lidocaine; Mathematical Computing; Memory; Models, Neurological; Neuronal Plasticity; Neurons; Rats; Regression Analysis; Signal Processing, Computer-Assisted; Synapses

2000
Neurokinin release produced by capsaicin acting on the central terminals and axons of primary afferents: relationship with N-methyl-D-aspartate and GABA(B) receptors.
    Neuroscience, 2003, Volume: 121, Issue:3

    Topics: Afferent Pathways; Analysis of Variance; Anesthetics, Local; Animals; Axons; Baclofen; Calcium; Capsaicin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Functional Laterality; GABA Agonists; Immunohistochemistry; In Vitro Techniques; Indoles; Isoindoles; Lidocaine; Microscopy, Confocal; Neurokinin-1 Receptor Antagonists; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Spinal Nerve Roots; Time Factors

2003
Retrograde GABA signaling adjusts sound localization by balancing excitation and inhibition in the brainstem.
    Neuron, 2008, Jul-10, Volume: 59, Issue:1

    Topics: Acoustic Stimulation; Action Potentials; Anesthetics, Local; Animals; Animals, Newborn; Auditory Pathways; Baclofen; Dose-Response Relationship, Drug; Ear; Egtazic Acid; Electric Stimulation; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Gerbillinae; In Vitro Techniques; Lidocaine; Models, Molecular; Neural Inhibition; Neurons; Olivary Nucleus; Organophosphorus Compounds; Patch-Clamp Techniques; Receptors, GABA-B; Sound Localization; Synaptic Transmission

2008