lidocaine and arginine

lidocaine has been researched along with arginine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's5 (21.74)18.2507
2000's10 (43.48)29.6817
2010's7 (30.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cieszkowski, M; Konturek, SJ; Obtulowicz, W; Tasler, J1
Cho, CH; Ko, JK; Tang, XL1
Maher, JW; Murray, J; Richardson, K; Sandler, AD; Schmidt, C1
Delbro, DS; Engberg, G1
Arvela, P; Mustajoki, P; Mustajoki, S; Pelkonen, O; Rautio, A1
Gay, WA; Harris, KM; Lee, R; Nitta, T; Schmid, RA; Schuessler, RB1
Itoh, Z; Suzuki, H; Tohara, K; Uchida, Y1
Lawand, NB; McNearney, T; Westlund, KN1
Bilge, SS; Celik, S; Kesim, Y; Kukula, O; Kurt, M1
DiCicco, RA; Graham, AM; Hursting, MJ; Inglis, AM; Sheth, SB; Tenero, DM1
Chen, S; Ma, SX1
Alexander, KS; Fink, JM; Honisko, ME; Mauro, VF; Militello, MA1
Edgerton, GB; Fozzard, HA; Hanck, DA; Lipkind, GM; McNulty, MM; Shah, RD1
Hanck, DA; Sheets, MF1
Cummins, TR1
Atuma, C; Engstrand, L; Henriksnäs, J; Holm, L; Phillipson, M; Sandler, S1
Kawahito, S; Kitahata, H; Takaishi, K1
Aparicio, S; Atilhan, M; Gutiérrez, A1
Chen, W; Fu, W; Marvizon, JC; Taylor, BK1

Reviews

1 review(s) available for lidocaine and arginine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for lidocaine and arginine

ArticleYear
Investigation of the interaction between argatroban and acetaminophen, lidocaine, or digoxin.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002, Jul-01, Volume: 59, Issue:13

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Antithrombins; Area Under Curve; Arginine; Confidence Intervals; Cross-Over Studies; Digoxin; Drug Interactions; Female; Half-Life; Humans; Lidocaine; Male; Metabolic Clearance Rate; Middle Aged; Pipecolic Acids; Sulfonamides

2002

Other Studies

21 other study(ies) available for lidocaine and arginine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Comparison of amino acids bathing the oxyntic gland area in the stimulation of gastric secretion.
    Gastroenterology, 1976, Volume: 70, Issue:1

    Topics: Amino Acids; Animals; Arginine; Atropine; Cysteine; Dogs; Fistula; Gastric Juice; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Leucine; Lidocaine; Metiamide; Pancreas; Pepsin A; Phenylalanine; Stimulation, Chemical; Stomach; Threonine

1976
The differential mechanisms of mild irritants on adaptive cytoprotection.
    Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1

    Topics: Adaptation, Physiological; Animals; Arginine; Atropine; Capsaicin; Chorionic Gonadotropin; Ethanol; Gastric Mucosa; Hexamethonium; Indomethacin; Irritants; Lidocaine; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Stomach Ulcer; Substance P

1994
Regulation of distal esophageal mucosal blood flow: the roles of nitric oxide and substance P.
    Surgery, 1993, Volume: 114, Issue:2

    Topics: Animals; Arginine; Dogs; Esophagus; Hydrochloric Acid; Immunohistochemistry; Lidocaine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Regional Blood Flow; Substance P; Vagotomy

1993
Are there tonically active, inhibitory motor nerves in the guinea-pig gallbladder?
    Acta physiologica Scandinavica, 1993, Volume: 149, Issue:2

    Topics: Animals; Arginine; Bethanechol; Bethanechol Compounds; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Lidocaine; Male; Motor Neurons; Muscle, Smooth; Nitroarginine; Time Factors

1993
Effects of heme arginate on cytochrome P450-mediated metabolism of drugs in patients with variegate porphyria and in healthy men.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:1

    Topics: Adult; Arginine; Caffeine; Coumarins; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Heme; Humans; Isoenzymes; Lidocaine; Male; Middle Aged; Porphyrias, Hepatic; Reference Values

1994
Retrograde infusion of lidocaine or L-arginine before reperfusion reduces myocardial infarct size.
    The Annals of thoracic surgery, 1998, Volume: 65, Issue:5

    Topics: Anesthetics, Local; Animals; Arginine; Cardiovascular Agents; Coloring Agents; Coronary Vessels; Echocardiography; Heart Ventricles; Image Processing, Computer-Assisted; Infusions, Intravenous; Lidocaine; Lissamine Green Dyes; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Random Allocation; Sodium Chloride; Swine; Tetrazolium Salts; Ventricular Function, Left

1998
Initiation of phase III contractions in the jejunum by atropine, hexamethonium and xylocaine in conscious dogs.
    Neurogastroenterology and motility, 2000, Volume: 12, Issue:1

    Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Arginine; Atropine; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Consciousness; Dogs; Enteric Nervous System; Enzyme Inhibitors; Gastrointestinal Motility; Hexamethonium; Indoles; Injections, Intra-Arterial; Jejunum; Lidocaine; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nicotinic Antagonists; Parasympatholytics; Peptide Fragments; Piperidines; Postprandial Period; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sulfonamides; Tetrodotoxin

2000
Amino acid release into the knee joint: key role in nociception and inflammation.
    Pain, 2000, Volume: 86, Issue:1-2

    Topics: Amino Acids; Anesthetics, Local; Animals; Arginine; Arthritis; Carrageenan; Chromatography, High Pressure Liquid; Citrulline; Glutamic Acid; Hindlimb; Injections, Intra-Articular; Joints; Kaolin; Lidocaine; Male; Pain; Rats; Rats, Sprague-Dawley; Synovial Fluid

2000
The role of nitrergic system in lidocaine-induced convulsion in the mouse.
    Japanese journal of pharmacology, 2001, Volume: 85, Issue:1

    Topics: Anesthetics, Local; Animals; Anticonvulsants; Arginine; Diazepam; Enzyme Inhibitors; Lidocaine; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Seizures

2001
Nitric oxide in the gracile nucleus mediates depressor response to acupuncture (ST36).
    Journal of neurophysiology, 2003, Volume: 90, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Bradycardia; Electroacupuncture; Heart Rate; Lidocaine; Male; Medulla Oblongata; Microinjections; Neural Conduction; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oligonucleotides, Antisense; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers

2003
Compatibility of argatroban with selected cardiovascular agents.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2004, Nov-15, Volume: 61, Issue:22

    Topics: Amiodarone; Anticoagulants; Arginine; Cardiovascular Agents; Drug Interactions; Drug Therapy, Combination; Fenoldopam; Furosemide; Humans; Infusions, Parenteral; Lidocaine; Milrinone; Natriuretic Peptide, Brain; Nitroglycerin; Nitroprusside; Pipecolic Acids; Sulfonamides; Vasopressins

2004
Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels.
    The Journal of physiology, 2007, Jun-01, Volume: 581, Issue:Pt 2

    Topics: Anesthetics, Local; Arginine; Aspartic Acid; Binding Sites; Cell Line; Cell Membrane Permeability; Glutamic Acid; Humans; Ion Channel Gating; Kinetics; Lidocaine; Lysine; Membrane Potentials; Models, Molecular; Molecular Structure; Muscle Proteins; Mutagenesis, Site-Directed; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenylalanine; Protein Conformation; Sodium Channel Blockers; Sodium Channels; Static Electricity; Transfection

2007
Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels.
    The Journal of physiology, 2007, Jul-01, Volume: 582, Issue:Pt 1

    Topics: Anesthetics, Local; Anti-Arrhythmia Agents; Arginine; Binding Sites; Biotin; Cell Line; Cysteine; Dose-Response Relationship, Drug; Humans; Ion Channel Gating; Kinetics; Lidocaine; Membrane Potentials; Muscle Proteins; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Protein Conformation; Protein Structure, Tertiary; Sodium Channel Blockers; Sodium Channels; Transfection

2007
Setting up for the block: the mechanism underlying lidocaine's use-dependent inhibition of sodium channels.
    The Journal of physiology, 2007, Jul-01, Volume: 582, Issue:Pt 1

    Topics: Anesthetics, Local; Anti-Arrhythmia Agents; Arginine; Binding Sites; Biotin; Cell Line; Cysteine; Humans; Ion Channel Gating; Kinetics; Lidocaine; Membrane Potentials; Muscle Proteins; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Protein Conformation; Protein Structure, Tertiary; Sodium Channel Blockers; Sodium Channels; Transfection

2007
Acute effects of Helicobacter pylori extracts on gastric mucosal blood flow in the mouse.
    World journal of gastroenterology, 2009, Jan-14, Volume: 15, Issue:2

    Topics: Animals; Arginine; Blood Flow Velocity; Gastric Mucosa; Helicobacter pylori; Lidocaine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type II; Signal Transduction; Water

2009
Local anesthetics inhibit nitric oxide production and L-arginine uptake in cultured bovine aortic endothelial cells.
    European journal of pharmacology, 2013, Mar-15, Volume: 704, Issue:1-3

    Topics: Anesthetics, Local; Animals; Aorta; Arginine; Cattle; Cells, Cultured; Endothelial Cells; Lidocaine; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Procaine

2013
Design of arginine-based therapeutic deep eutectic solvents as drug solubilization vehicles for active pharmaceutical ingredients.
    Physical chemistry chemical physics : PCCP, 2019, May-28, Volume: 21, Issue:20

    Topics: Arginine; Drug Delivery Systems; Lidocaine; Pharmaceutical Preparations; Solubility; Solvents

2019
Neuropeptide Y release in the rat spinal cord measured with Y1 receptor internalization is increased after nerve injury.
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Calcium Channel Blockers; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Excitatory Amino Acid Antagonists; Hyperalgesia; Indoles; Interneurons; Lidocaine; Male; Microscopy, Confocal; Neuropeptide Y; Nociception; omega-Conotoxins; Peripheral Nerve Injuries; Posterior Horn Cells; Potassium Chloride; Protein Transport; Protein Tyrosine Phosphatases; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide Y; Sensory System Agents; Spinal Cord; Spinal Nerve Roots; TRPV Cation Channels; Voltage-Gated Sodium Channel Blockers

2019