lidocaine and antipyrine

lidocaine has been researched along with antipyrine in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (40.74)	18.7374
1990's	6 (11.11)	18.2507
2000's	17 (31.48)	29.6817
2010's	9 (16.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Caron, G; Ermondi, G	1
Jolivette, LJ; Ward, KW	1
Carrupt, PA; Martel, S; Ottaviani, G	2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Conradi, R; Lee, PH; Shanmugasundaram, V	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Adjepon-Yamoah, KK; Finlayson, ND; Forrest, JA; Prescott, LF	3
Azarnoff, DL; Gugler, R; Lain, P	1
Adjepon-Yamoah, KK; Prescott, LF; Talbot, RG	1
Caccia, S; Conti, I; Duan, L; Tridico, RV	1
Weiss, M	1
Becker, A; Bołdys, H; Hartleb, M; Kloc, T; Mańczyk, I	1
Belpaire, FM; Bogaert, MG; Chindavijak, B	3
Blyden, GT; Greenblatt, DJ; LeDuc, BW; Scavone, JM	1
Blyden, GT; Engelking, LR; Greenblatt, DJ; Lofstedt, J	2
Ampelas, M; Côté, J; Fortunet-Fouin, H; Huet, PM; LaMarre, L; Pomier-Layrargues, G; Thibeault, MJ; Villeneuve, JP	1
Michos, N; Stocker, H; Weippl, G	1
Hamshaw-Thomas, A; Reynolds, F	1
Adjepon-Yamoah, KK; Nimmo, J; Prescott, LF	1
Branch, RA; Nies, AS; Shand, DG	1
Furkert, K	1
Dinnendahl, V; Kalbhen, DA	1
Cheong, DK; Gangarosa, LP	1
Hedges, A; Makki, KA; Perucca, E; Richens, A	1
Epping, J; Fuchshofen-Röckel, M; Heusler, H; Richter, E; Zilly, W	1
Ala-Kokko, TI; Herva, R; Hollmén, AI; Pelkonen, O; Pienimäki, P; Vähäkangas, K	1
Ferrara, SD; Frison, G; Mazzo, M; Orlando, R; Padrini, R; Palatini, P; Tedeschi, L; Zordan, R	1
Tanaka, E; Yasuhara, H	1
Koester, A; Roberts, MS; Weiss, M; Wu, ZY	1
Gillardin, JM; Heulard, I; Verleye, M	1
Brendel, K; Mayersohn, M; Sinha, V	1
Baker, AB; Gao, L; Ramzan, I	1
He, J; Huang, Y; Luo, G; Miao, Z; Wang, X; Wang, Y; Wu, T; Zhao, Z	1
Sagesaka, A; See, GL; Sugasawa, S; Sugibayashi, K; Todo, H	1
Ba, JB; Chu, ZY; Feng, X; Liu, WH; Zhang, XD; Zou, YX	1

Reviews

5 review(s) available for lidocaine and antipyrine

Article	Year
Drug metabolism in liver disease. Journal of clinical pathology. Supplement (Royal College of Pathologists), 1975, Volume: 9 Topics: Acetaminophen; Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Chronic Disease; Half-Life; Humans; Isoniazid; Lidocaine; Liver; Liver Diseases; Pharmaceutical Preparations; Tolbutamide	1975
Hemodynamic drug interactions. Cardiovascular clinics, 1974, Volume: 6, Issue:2 Topics: Animals; Antipyrine; Dogs; Dopamine; Drug Interactions; Enzyme Induction; Glucagon; Half-Life; Hemodynamics; Humans; Lidocaine; Liver Circulation; Macaca mulatta; Metabolic Clearance Rate; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Propranolol; Time Factors	1974
[Otologic agents. 13]. Pharmazeutische Praxis, 1967, Volume: 9 Topics: Adrenal Cortex Hormones; Aminopyrine; Anesthetics, Local; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Antipyrine; Benzocaine; Chloramphenicol; Disinfectants; Ear Diseases; Formaldehyde; Humans; Hydrocortisone; Lidocaine; Neomycin; Nitrofurazone; Prednisolone; Procaine; Tetracaine; Toluene	1967
[Evaluation of liver function in liver diseases using drugs as indicators]. The Journal of toxicological sciences, 1997, Volume: 22, Issue:3 Topics: Aminopyrine; Antipyrine; Erythromycin; Humans; Lidocaine; Liver; Liver Diseases; Liver Function Tests; Trimethadione	1997
Potential use of pharmacological markers to quantitatively assess liver function during liver transplantation surgery. Anaesthesia and intensive care, 2000, Volume: 28, Issue:4 Topics: Adult; Antipyrine; Biomarkers; Breath Tests; Caffeine; Coloring Agents; Galactose; Humans; Indocyanine Green; Lidocaine; Liver; Liver Function Tests; Liver Transplantation; Postoperative Period; Reference Values	2000

Trials

2 trial(s) available for lidocaine and antipyrine

Article	Year
Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media. Arzneimittel-Forschung, 1985, Volume: 35, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Child, Preschool; Drug Combinations; Humans; Infant; Lidocaine; Otitis Media; Pain; Phenylpropionates; Solutions; Suprofen; Time Factors	1985
A comparative study of antipyrine and lignocaine disposition in normal subjects and in patients treated with enzyme-inducing drugs. British journal of clinical pharmacology, 1980, Volume: 10, Issue:5 Topics: Adolescent; Adult; Anticonvulsants; Antipyrine; Biological Availability; Enzyme Induction; Glucaric Acid; Humans; Kinetics; Lidocaine; Middle Aged	1980

Article

Year

Clinical experience and results of treatment with suprofen in pediatrics. 4th communication: Assessment of pain in babies and infants/Analgesic effect of suprofen syrup in otitis media.

Arzneimittel-Forschung, 1985, Volume: 35, Issue:11

Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Child, Preschool; Drug Combinations; Humans; Infant; Lidocaine; Otitis Media; Pain; Phenylpropionates; Solutions; Suprofen; Time Factors

1985

A comparative study of antipyrine and lignocaine disposition in normal subjects and in patients treated with enzyme-inducing drugs.

British journal of clinical pharmacology, 1980, Volume: 10, Issue:5

Topics: Adolescent; Adult; Anticonvulsants; Antipyrine; Biological Availability; Enzyme Induction; Glucaric Acid; Humans; Kinetics; Lidocaine; Middle Aged

1980

Other Studies

47 other study(ies) available for lidocaine and antipyrine

Article	Year
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability. Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13 Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water	2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Antipyrine, paracetamol, and lignocaine elimination in chronic liver disease. British medical journal, 1977, May-28, Volume: 1, Issue:6073 Topics: Acetaminophen; Adult; Aged; Antipyrine; Chronic Disease; Female; Half-Life; Humans; Kinetics; Lidocaine; Liver; Liver Diseases; Male; Middle Aged; Prothrombin Time; Serum Albumin	1977
Effect of portacaval shunt on the disposition of drugs with and without first-pass effect. The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:3 Topics: Animals; Antipyrine; Biological Availability; Dogs; Female; Half-Life; Kinetics; Lidocaine; Liver; Male; Portacaval Shunt, Surgical; Salicylamides; Time Factors	1975
Proceedings: Antipyrine, lingocaine and paracetamol metabolism in chronic liver disease. Gut, 1975, Volume: 16, Issue:10 Topics: Acetaminophen; Adult; Aged; Antipyrine; Chronic Disease; Female; Humans; Lidocaine; Liver Diseases; Male; Middle Aged	1975
Impaired Lignocaine metabolism in patients with myocardial infarction and cardiac failure. British medical journal, 1976, Apr-17, Volume: 1, Issue:6015 Topics: Adult; Aged; Antipyrine; Half-Life; Heart Failure; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Shock, Cardiogenic	1976
Effects of L-fenfluramine on rat liver drug-metabolizing enzymes. Research communications in chemical pathology and pharmacology, 1991, Volume: 71, Issue:2 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Fenfluramine; Lidocaine; Liver; Male; Mixed Function Oxygenases; Rats; Rats, Inbred Strains	1991
Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction. Clinical pharmacokinetics, 1990, Volume: 18, Issue:5 Topics: Absorption; Antipyrine; Biological Availability; Caffeine; Diphenhydramine; Dose-Response Relationship, Drug; Humans; Ketanserin; Lidocaine; Liver Diseases; Metronidazole; Nomifensine; Triamterene	1990
[Usefulness of the evaluation of blood supply and mass of the liver for predicting the rate of pharmacokinetics of lidocaine, propranolol and phenazone]. Polskie Archiwum Medycyny Wewnetrznej, 1989, Volume: 81, Issue:6 Topics: Adult; Aged; Antipyrine; Female; Humans; Lidocaine; Liver; Liver Circulation; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Portal System; Propranolol	1989
In-vitro biotransformation of antipyrine, lignocaine and propranolol in the liver of rats with turpentine-induced inflammation. The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:11 Topics: Aminopyrine N-Demethylase; Animals; Antipyrine; Biotransformation; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Hepatitis, Animal; In Vitro Techniques; Lidocaine; Liver; Male; Propranolol; Rats; Rats, Inbred Strains; Turpentine	1987
Effect of inflammation and proadifen on the disposition of antipyrine, lignocaine and propranolol in rat isolated perfused liver. The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:12 Topics: Animals; Antipyrine; In Vitro Techniques; Inflammation; Lidocaine; Liver; Male; Proadifen; Propranolol; Rats; Rats, Inbred Strains; Turpentine	1987
Effect of antipyrine coadministration on the kinetics of acetaminophen and lidocaine. European journal of clinical pharmacology, 1988, Volume: 35, Issue:4 Topics: Acetaminophen; Adult; Antipyrine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Kinetics; Lidocaine; Male	1988
Effect of inflammation on the metabolism of antipyrine, lidocaine and propranolol in isolated rat hepatocytes. Pharmacology, 1988, Volume: 36, Issue:4 Topics: Animals; Antipyrine; Inflammation; Lidocaine; Liver; Male; Proadifen; Propranolol; Rats; Rats, Inbred Strains; Turpentine	1988
Pharmacokinetics of antipyrine, acetaminophen and lidocaine in fed and fasted horses. Journal of veterinary pharmacology and therapeutics, 1987, Volume: 10, Issue:1 Topics: Acetaminophen; Animals; Antipyrine; Fasting; Female; Horses; Kinetics; Lidocaine; Liver	1987
Drug disposition in patients with HBsAg-positive chronic liver disease. Digestive diseases and sciences, 1987, Volume: 32, Issue:7 Topics: Adult; Aminopyrine; Antipyrine; Female; Hepatitis; Hepatitis B Surface Antigens; Hepatitis, Chronic; Humans; Indocyanine Green; Lidocaine; Liver; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged	1987
Antipyrine and lidocaine are cleared faster in horses than in humans: acetaminophen may be handled similarly. Pharmacology, 1987, Volume: 34, Issue:4 Topics: Acetaminophen; Animals; Antipyrine; Female; Horses; Humans; Kinetics; Lidocaine; Species Specificity	1987
Placental transfer of bupivacaine, pethidine and lignocaine in the rabbit. Effect of umbilical flow rate and protein content. British journal of obstetrics and gynaecology, 1985, Volume: 92, Issue:7 Topics: Animals; Antipyrine; Blood Flow Velocity; Blood Proteins; Bupivacaine; Female; Lidocaine; Maternal-Fetal Exchange; Meperidine; Perfusion; Pregnancy; Protein Binding; Rabbits; Umbilical Cord	1985
Gross impairment of hepatic drug metabolism in a patient with chronic liver disease. British medical journal, 1974, Nov-16, Volume: 4, Issue:5941 Topics: Adult; Antipyrine; Biotransformation; Chronic Disease; Female; Half-Life; Hepatitis; Humans; Jaundice; Lidocaine; Liver; Male	1974
[Pharmacology studies on the influencing of chondroitin sulfate decomposition in vitro]. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:2 Topics: Aminopyrine; Anti-Inflammatory Agents; Antipyrine; Aspirin; Chemical Phenomena; Chemistry; Chloroquine; Chondroitin; Copper; Densitometry; Flavonoids; Flufenamic Acid; Glucosamine; Hyaluronoglucosaminidase; Iron; Lidocaine; Male; Malonates; Methylamines; Oxyphenbutazone; Prednisolone; Rutin; Sodium Chloride; Sodium Salicylate; Sulfates; Testis; Triazines	1971
Local anesthetics: inhibition of subcutaneous absorption in rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:4 Topics: Absorption; Animals; Antipyrine; Cocaine; Depression, Chemical; Injections, Subcutaneous; Lidocaine; Phosphates; Phosphorus Isotopes; Prilocaine; Procaine; Rats; Tetracaine	1970
[Drug metabolism in patients with liver disease (author's transl)]. Leber, Magen, Darm, 1980, Volume: 10, Issue:5 Topics: Acute Disease; Adult; Antipyrine; Biological Availability; Biotransformation; Cholestasis; Female; Hepatitis; Hexobarbital; Humans; Lidocaine; Liver Cirrhosis; Liver Diseases; Male; Methohexital; Middle Aged	1980
Transfer of lidocaine and bupivacaine across the isolated perfused human placenta. Pharmacology & toxicology, 1995, Volume: 77, Issue:2 Topics: Anesthetics, Local; Antipyrine; Bupivacaine; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Maternal-Fetal Exchange; Oxygen Consumption; Partial Pressure; Placenta; Pregnancy; Reference Standards	1995
Effect of moderate or severe liver dysfunction on the pharmacokinetics of gamma-hydroxybutyric acid. European journal of clinical pharmacology, 1996, Volume: 50, Issue:4 Topics: Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Humans; Hydroxybutyrates; Lidocaine; Liver Cirrhosis; Male; Middle Aged	1996
Distribution kinetics of diazepam, lidocaine and antipyrine in the isolated perfused rat hindlimb. Pharmaceutical research, 1997, Volume: 14, Issue:11 Topics: Animals; Antipyrine; Diazepam; Hindlimb; In Vitro Techniques; Lidocaine; Male; Perfusion; Rats; Rats, Wistar; Tissue Distribution	1997
Phenazone potentiates the local anaesthetic effect of lidocaine in mice. Pharmacological research, 2000, Volume: 41, Issue:5 Topics: Anesthetics, Local; Animals; Antipyrine; Dose-Response Relationship, Drug; Drug Synergism; Lidocaine; Male; Mice	2000
A simplified isolated perfused rat liver apparatus: characterization and measurement of extraction ratios of selected compounds. Life sciences, 2000, Mar-31, Volume: 66, Issue:19 Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Central Nervous System Depressants; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethanol; In Vitro Techniques; Lidocaine; Liver; Male; Models, Biological; Oxygen Consumption; Perfusion; Rats; Rats, Sprague-Dawley	2000
The Therapeutic Effect of Stellate Ganglion Block on Facial Nerve Palsy in Patients with Type 2 Diabetes Mellitus. European neurology, 2015, Volume: 74, Issue:1-2 Topics: Adult; Anesthetics, Local; Antipyrine; Aspirin; Autonomic Nerve Block; Blood Glucose; Dexamethasone; Diabetes Mellitus, Type 2; Edaravone; Facial Nerve Diseases; Facial Paralysis; Female; Free Radical Scavengers; Glucocorticoids; Humans; Lidocaine; Male; Middle Aged; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Prednisone; Retrospective Studies; Stellate Ganglion; Thiamine; Treatment Outcome; Vinca Alkaloids; Vitamin B 12; Vitamin B Complex	2015
Eyelid skin as a potential site for drug delivery to conjunctiva and ocular tissues. International journal of pharmaceutics, 2017, Nov-25, Volume: 533, Issue:1 Topics: Administration, Cutaneous; Aminopyrine; Animals; Antipyrine; Diclofenac; Eye; Lidocaine; ortho-Aminobenzoates; Permeability; Pilocarpine; Rats, Hairless; Rhodamines; Skin; Skin Absorption	2017
Preclinical safety assessment of antipyrine combined with lidocaine hydrochloride as ear drops. Regulatory toxicology and pharmacology : RTP, 2019, Volume: 103 Topics: Animals; Antipyrine; Dose-Response Relationship, Drug; Drug Combinations; Ear; Erythrocytes; Female; Gastrointestinal Tract; Guinea Pigs; Lidocaine; Liver; Male; Mice; Mice, Inbred ICR; Pharmaceutical Solutions; Rabbits; Rats; Rats, Sprague-Dawley	2019