lidocaine and amiloride

lidocaine has been researched along with amiloride in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's8 (34.78)18.2507
2000's10 (43.48)29.6817
2010's3 (13.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bagal, SK; Brown, AD; Cox, PJ; Omoto, K; Owen, RM; Pryde, DC; Sidders, B; Skerratt, SE; Stevens, EB; Storer, RI; Swain, NA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carmeliet, E; Tytgat, J; Vereecke, J1
Dart, AM; Riemersma, RA1
Nebel, U; Wermelskirchen, D; Wilffert, B; Wirth, A1
Ensor, DM1
Boucher, RC; Bromberg, PA; Buntin, WH; Gatzy, JT; Knowles, MR1
Haigney, MC; Lakatta, EG; Silverman, HS; Stern, MD1
Geada, MM; Singh, J; Wisdom, DM1
Dukhanin, AS; Galenko-Iaroshevskiĭ, PA; Khankoeva, AI1
Bidani, A; Heming, TA1
Dai, DZ; De Clerck, F; Lu, HR; Remeysen, P; Saels, A; Yang, P1
Chan, MH; Farley, JM1
Chiba, T; Marcus, DC1
Barbry, P; Clerici, C; Folkesson, HG; Jayr, C; Laffon, M; Matthay, MA; Pittet, JF; Wang, Y1
Gupta, A; Gupta, S; Moudgil, P; Sharma, A; Tiwary, AK1
Bánfalvi, G; Kiss-Tóth, E; Petkó, M; Roszer, T; Szentmiklósi, AJ1
Kasaba, T; Onizuka, S; Takasaki, M; Tamura, R1
Fujii, T; Haga, T; Kawashima, K; Masai, M; Misawa, H; Moriwaki, Y; Okuda, T; Takada-Takatori, Y1

Reviews

2 review(s) available for lidocaine and amiloride

ArticleYear
Ion channels as therapeutic targets: a drug discovery perspective.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Drug Discovery; Humans; Ion Channels; Models, Molecular; Phylogeny

2013
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

21 other study(ies) available for lidocaine and amiloride

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A combined study of sodium current and T-type calcium current in isolated cardiac cells.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 417, Issue:2

    Topics: Adenosine; Amiloride; Animals; Calcium Channels; Flunarizine; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Kinetics; Lidocaine; Myocardium; Perfusion; Rats; Sodium Channels; Tetrodotoxin

1990
Noradrenaline release from the rat heart during anoxia: effects of changes in extracellular sodium concentration and inhibition of sodium uptake mechanisms.
    Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:1

    Topics: Amiloride; Animals; Extracellular Space; Hypoxia; In Vitro Techniques; Lidocaine; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Sodium

1991
45Ca2+ movements induced by Ca2+ chloride in isolated rat aorta under K(+)-free conditions.
    European journal of pharmacology, 1991, Jan-17, Volume: 192, Issue:3

    Topics: Amiloride; Animals; Aorta, Thoracic; Benzothiazoles; Calcium; Calcium Chloride; Calcium Radioisotopes; Flunarizine; In Vitro Techniques; Indomethacin; Lanthanum; Lidocaine; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Piperidines; Potassium; Rats; Thiazoles; Vasoconstriction

1991
Proceedings: Effect of diuretics and vagus blockade on the release of avian prolactin.
    The Journal of endocrinology, 1974, Volume: 63, Issue:2

    Topics: Amiloride; Animals; Ducks; Electric Stimulation; Electrophoresis, Polyacrylamide Gel; Lidocaine; Pituitary Gland; Prolactin; Pyrazines; Salt Gland; Vagus Nerve

1974
Measurements of transepithelial electric potential differences in the trachea and bronchi of human subjects in vivo.
    The American review of respiratory disease, 1982, Volume: 126, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Amiloride; Bronchi; Epithelium; Female; Humans; Lidocaine; Male; Membrane Potentials; Middle Aged; Smoking; Trachea

1982
Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading.
    Circulation, 1994, Volume: 90, Issue:1

    Topics: Amiloride; Animals; Benzofurans; Benzothiazoles; Calcium; Calcium Channel Blockers; Cell Separation; Ethers, Cyclic; Fluorescent Dyes; Hypoxia; Lidocaine; Myocardial Contraction; Myocardium; Piperidines; Rats; Sodium; Sodium Channel Blockers; Sodium-Hydrogen Exchangers; Tetrodotoxin; Thiazoles

1994
Characterization of a sodium-dependent magnesium efflux from magnesium-loaded rat pancreatic acinar cells.
    Experimental physiology, 1996, Volume: 81, Issue:3

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Biological Transport; Bumetanide; Choline; Dinitrophenols; Female; In Vitro Techniques; Lidocaine; Magnesium; Male; Ouabain; Pancreas; Quinidine; Rats; Rats, Sprague-Dawley; Time Factors

1996
[A study of the mechanism of lidocaine and befol effects on Na-exchange in normal cardiomyocytes and in the experimental model of hypoxia in vitro].
    Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 122, Issue:7

    Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Benzamides; Benzofurans; Cell Hypoxia; Cells, Cultured; Enzyme Inhibitors; Heart; Lidocaine; Morpholines; Myocardium; Ouabain; Rats; Sodium; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Spectrometry, Fluorescence

1996
Effects of lidocaine on cytosolic pH regulation and stimulus-induced effector functions in alveolar macrophages.
    Lung, 1997, Volume: 175, Issue:6

    Topics: Acid-Base Equilibrium; Adenosine Triphosphate; Amiloride; Anesthetics, Local; Animals; Anti-Bacterial Agents; Cell Survival; Cytosol; Enzyme Inhibitors; Hydrogen-Ion Concentration; Lidocaine; Macrolides; Macrophages, Alveolar; Male; Proton-Translocating ATPases; Rabbits; Sodium-Hydrogen Exchangers; Superoxides; Tumor Necrosis Factor-alpha; Vacuolar Proton-Translocating ATPases

1997
Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.
    European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3

    Topics: Amiloride; Anesthesia; Animals; Arrhythmias, Cardiac; Benzothiazoles; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels; Heart Rate; Lidocaine; Male; Myocardial Reperfusion Injury; Piperidines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Sodium Channels; Thiazoles; Verapamil

1999
Lidocaine-induced alterations in agonist-induced ion transport of cultured swine tracheal submucosal gland cells.
    Toxicology and applied pharmacology, 2000, Sep-15, Volume: 167, Issue:3

    Topics: Acetylcholine; Amiloride; Anesthetics, Local; Animals; Atropine; Biological Transport; Cell Survival; Cells, Cultured; Drug Interactions; Electrophysiology; Ions; Isoproterenol; Lidocaine; Male; Respiratory Mucosa; Swine; Trachea

2000
Basolateral K+ conductance establishes driving force for cation absorption by outer sulcus epithelial cells.
    The Journal of membrane biology, 2001, Nov-15, Volume: 184, Issue:2

    Topics: Absorption; Amiloride; Animals; Barium; Cations, Monovalent; Electric Conductivity; Enzyme Inhibitors; Epithelial Cells; Gerbillinae; Lidocaine; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Quinine; Sodium-Potassium-Exchanging ATPase

2001
Lidocaine induces a reversible decrease in alveolar epithelial fluid clearance in rats.
    Anesthesiology, 2002, Volume: 96, Issue:2

    Topics: Amiloride; Anesthetics, Local; Animals; Blood Gas Analysis; Body Fluids; Diuretics; Epithelium; Hemodynamics; Injections; Injections, Intravenous; Lidocaine; Male; Oocytes; Proteins; Pulmonary Alveoli; Pulmonary Gas Exchange; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Sodium Channels; Xenopus

2002
Potentiation of spermicidal activity of 2',4'-dichlorobenzamil by lidocaine.
    Indian journal of experimental biology, 2002, Volume: 40, Issue:12

    Topics: Amiloride; Animals; Humans; Lidocaine; Male; Rabbits; Spermatocidal Agents; Spermatozoa

2002
Phe-met-arg-phe (FMRF)-amide is a substrate source of NO synthase in the gastropod nervous system.
    Cell and tissue research, 2006, Volume: 325, Issue:3

    Topics: Amiloride; Animals; FMRFamide; Gastropoda; Immunohistochemistry; Lidocaine; Muscle Contraction; NADPH Dehydrogenase; Nervous System; Neuropeptides; Nitric Oxide Synthase; Sodium Channel Blockers; Tetrodotoxin

2006
Lidocaine increases intracellular sodium concentration through a Na+-H+ exchanger in an identified Lymnaea neuron.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:5

    Topics: Amiloride; Anesthetics, Local; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Lidocaine; Lymnaea; Mepivacaine; Microscopy, Fluorescence; Neurons; Prilocaine; Sodium; Sodium-Hydrogen Exchangers; Up-Regulation

2008
Acetylcholine synthesis and release in NIH3T3 cells coexpressing the high-affinity choline transporter and choline acetyltransferase.
    Journal of neuroscience research, 2009, Volume: 87, Issue:13

    Topics: Acetylcholine; Amiloride; Animals; Cation Transport Proteins; Choline; Choline O-Acetyltransferase; Hemicholinium 3; Lidocaine; Membrane Lipids; Mice; NIH 3T3 Cells; Organic Cation Transport Proteins; Phospholipids; Procaine; Rats; Recombinant Fusion Proteins; Sodium

2009