lidocaine and allopurinol

lidocaine has been researched along with allopurinol in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's5 (17.24)18.2507
2000's12 (41.38)29.6817
2010's10 (34.48)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Barstow, L; Small, RE1
Ball, GV; Freeman, D1
Adam, R; Astarcioglu, I; Azoulay, D; Bao, YM; Bismuth, H; Bonhomme, L; Chiche, L; Fredj, G; Lemoine, A1
Davies, EA; Elkhammas, EA; Ferguson, RM; Greenson, J; Henry, ML; Salazar, A; Tesi, RJ1
Groothuis, GM; Hof, IH; Kranenburg, K; Maring, JK; Meijer, DK; Merema, M; Olinga, P; Slooff, MJ1
Cifuentes, A; García-Valdecasas, JC; Gonzalez, FX; Grande, L; López-Boado, MA; Net, M; Palacín, J; Rimola, A; Rull, R; Tabet, J; Taurá, P; Valero, R; Visa, J1
Demiryurek, AT; Gunaydin, B1
Asahiyama, M; Inagi, T; Kanebako, M; Makino, K; Nakajima, T; Ohtsuki, E; Terada, H; Tomoda, K1
Hanken, I; Sander, CA; Schimmer, M1
Aftab, A; Boutelle, M; Cook, T; Dobson, GP; Gowers, S; Hamaoui, K; Papalois, V; Rudd, D1
Earnest, R; Goodman, MD; McGlone, E; Morris, MC; Singer, KE; Stevens-Topie, S; Wallen, TE1

Reviews

1 review(s) available for lidocaine and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

28 other study(ies) available for lidocaine and allopurinol

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Liver function assessment by drug metabolism.
    Pharmacotherapy, 1990, Volume: 10, Issue:4

    Topics: Acetamides; Adult; Allopurinol; Aminopyrine; Caffeine; Half-Life; Humans; Indocyanine Green; Lidocaine; Liver; Liver Circulation; Liver Diseases; Liver Function Tests; Metabolic Clearance Rate; Middle Aged; Oxypurinol; Pyrimidines; Sorbitol

1990
Management of chronic and recurrent gout.
    Modern treatment, 1971, Volume: 8, Issue:4

    Topics: Adrenocorticotropic Hormone; Allopurinol; Chronic Disease; Colchicine; Dexamethasone; Diet Therapy; Gout; Humans; Indomethacin; Lidocaine; Phenylbutazone; Prednisolone; Probenecid; Recurrence; Synovial Fluid; Uric Acid

1971
Limits of the MEGX test in the selection of liver grafts for transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Adenosine; Adult; Allopurinol; Female; Glutathione; Graft Survival; Humans; Insulin; Lidocaine; Liver; Liver Function Tests; Liver Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Prognosis; Raffinose; Solutions; Tissue Donors; Treatment Outcome

1993
Safe use of liver donors with MEGX values less than 90 ng/mL.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Adenosine; Adult; Alanine Transaminase; Allopurinol; Analysis of Variance; Aspartate Aminotransferases; Female; Glutathione; Humans; Insulin; Lidocaine; Liver Function Tests; Liver Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Prothrombin Time; Raffinose; Solutions; Tissue Donors

1993
Value of the in vitro or in vivo monoethylglycinexylidide test for predicting liver graft function.
    Transplantation, 1997, Jul-15, Volume: 64, Issue:1

    Topics: Adenosine; Allopurinol; Glutathione; Humans; Insulin; Lidocaine; Liver Transplantation; Organ Preservation; Organ Preservation Solutions; Raffinose; Tissue Donors

1997
Value of MEGX test in predicting survival after liver transplantation from non-heart-beating donor pigs.
    Transplantation proceedings, 1997, Volume: 29, Issue:8

    Topics: Adenosine; Allopurinol; Animals; Glutathione; Graft Survival; Heart Arrest; Insulin; Lidocaine; Liver; Liver Transplantation; Organ Preservation; Organ Preservation Solutions; Raffinose; Survival Rate; Swine; Tissue Donors

1997
Interaction of lidocaine with reactive oxygen and nitrogen species.
    European journal of anaesthesiology, 2001, Volume: 18, Issue:12

    Topics: Acridines; Anesthetics, Local; Cell-Free System; Dose-Response Relationship, Drug; Ferrous Compounds; Humans; Hydrogen Peroxide; Hypochlorous Acid; Leukocytes; Lidocaine; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Oxidants; Peroxynitrous Acid; Reactive Oxygen Species; Xanthine; Xanthine Oxidase

2001
Preparation and properties of carrageenan microspheres containing allopurinol and local anesthetic agents for the treatment of oral mucositis.
    Colloids and surfaces. B, Biointerfaces, 2009, Jun-01, Volume: 71, Issue:1

    Topics: Allopurinol; Anesthetics; Carrageenan; Drug Carriers; Lidocaine; Microscopy, Electron, Scanning; Microspheres; Stomatitis; Surface Properties

2009
Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2010, Volume: 8, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Bacterial Infections; Ciprofloxacin; Drug Combinations; Female; Folic Acid; Gout Suppressants; Humans; Hydroxocobalamin; Lidocaine; Male; Middle Aged; Phenytoin; Prednisone; Pyridoxine; Stevens-Johnson Syndrome; Superinfection; Survival Rate; Trimethoprim, Sulfamethoxazole Drug Combination

2010
An ex vivo comparison of adenosine and lidocaine solution and University of Wisconsin solution for hypothermic machine perfusion of porcine kidneys: potential for development.
    The Journal of surgical research, 2017, Volume: 208

    Topics: Adenosine; Allopurinol; Animals; Glomerular Filtration Rate; Glutathione; Hypothermia, Induced; Insulin; Kidney; Lidocaine; Microdialysis; Organ Preservation Solutions; Oxygen Consumption; Perfusion; Raffinose; Swine

2017
Postinjury treatments to make early tactical aeromedical evacuation practical for the brain after TBI.
    The journal of trauma and acute care surgery, 2021, 08-01, Volume: 91, Issue:2S Suppl 2

    Topics: Adenosine; Air Ambulances; Allopurinol; Amitriptyline; Animals; Brain; Brain Chemistry; Brain Injuries, Traumatic; Cytokines; Disease Models, Animal; Emergency Medical Services; Lidocaine; Magnesium; Male; Mice; Mice, Inbred C57BL; Propranolol; Rotarod Performance Test

2021