liarozole has been researched along with ketoconazole in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 9 (60.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodie, AM; Clement, OO; Gediya, LK; Goloubeva, OG; Handratta, VD; Huynh, CK; Nanne, IP; Njar, VC; Patel, JB; Soprano, DR | 1 |
| Brancale, A; Coogan, MP; Elford, C; Evans, BA; Gomaa, MS; Jarno, L; McClelland, R; Nicholson, RI; Ooi, LL; Simons, C; Yee, SW | 1 |
| Muftuoglu, Y; Mustata, G | 1 |
| Aboraia, AS; Brancale, A; DeLuca, HF; Ferla, S; Ochalek, JT; Pepper, CJ; Simons, C; Zhu, J | 1 |
| Denis, L; Mahler, C | 1 |
| Bruynseels, J; Coene, MC; De Coster, R; Freyne, E; Raeymaekers, A; Sanz, G; Snoeck, E; Van Rooy, P; Vanden Bussche, G; Wouters, W | 1 |
| Bellens, D; Janssen, PA; Roels, I; Vanden Bossche, H; Willemsens, G | 1 |
| Coene, MC; Cools, W; Goossens, J; Monbaliu, J; Van Wauwe, JP | 1 |
| De Coster, R; Denis, L; Mahler, C | 1 |
| Denis, L; Mahler, C; Verhelst, J | 1 |
| Bruynseels, J; De Coster, R; Wouters, W | 1 |
| Bouillon, R; Marcelis, S; Tan, BK; Verstuyf, A; Zhao, J | 1 |
| Akaza, H; Fujikura, T; Ideyama, Y; Ishikawa, H; Kudoh, M; Nakahara, T; Nanya, T; Okada, M; Shikama, H; Susaki, Y; Tanimoto, K; Yoden, T | 1 |
| Maden, M; Sonneveld, E; van den Brink, CE; van der Leede, BJ; van der Saag, PT | 1 |
| Hosaka, M; Takeda, M | 1 |
5 review(s) available for liarozole and ketoconazole
| Article | Year |
|---|---|
Management of relapsing disease in prostate cancer.
Topics: Aminoglutethimide; Androgen Antagonists; Antineoplastic Agents; Combined Modality Therapy; Estrogens; Humans; Imidazoles; Ketoconazole; Male; Neoplasm Metastasis; Orchiectomy; Palliative Care; Prostatic Neoplasms; Recurrence | 1992 |
From 14 alpha-demethylase inhibitors in fungal cells to androgen and oestrogen biosynthesis inhibitors in mammalian cells.
Topics: Androgen Antagonists; Animals; Antifungal Agents; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estrogen Antagonists; Humans; Imidazoles; Ketoconazole; Oxidoreductases; Sterol 14-Demethylase; Triazoles | 1990 |
Ketoconazole and liarozole in the treatment of advanced prostatic cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Glucocorticoids; Humans; Imidazoles; Ketoconazole; Male; Middle Aged; Mineralocorticoids; Neoplasm Recurrence, Local; Neoplasm Staging; Prostatic Neoplasms; Remission Induction; Testosterone | 1993 |
P450-dependent enzymes as targets for prostate cancer therapy.
Topics: Adenocarcinoma; Aldehyde-Lyases; Androgen Antagonists; Androgens; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Cattle; Clinical Trials as Topic; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Imidazoles; Ketoconazole; Male; Mice; Neoplasm Proteins; Prostatic Neoplasms; Rats; Rats, Wistar; Salvage Therapy; Steroid 17-alpha-Hydroxylase; Tretinoin; Tumor Cells, Cultured | 1996 |
[Inhibitors of the key enzymes of androgen synthesis: potential agents as targets for prostate cancer].
Topics: 17-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androstenes; Androstenols; Animals; Antineoplastic Agents, Hormonal; Carbazoles; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Male; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone | 2000 |
1 trial(s) available for liarozole and ketoconazole
| Article | Year |
|---|---|
Ketoconazole and liarozole in the treatment of advanced prostatic cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Glucocorticoids; Humans; Imidazoles; Ketoconazole; Male; Middle Aged; Mineralocorticoids; Neoplasm Recurrence, Local; Neoplasm Staging; Prostatic Neoplasms; Remission Induction; Testosterone | 1993 |
10 other study(ies) available for liarozole and ketoconazole
| Article | Year |
|---|---|
Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cricetinae; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Microsomes, Liver; Neoplasm Transplantation; Prostatic Neoplasms; Retinoic Acid 4-Hydroxylase; Stereoisomerism; Transplantation, Heterologous; Tretinoin | 2004 |
Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays.
Topics: Binding Sites; Cell Line, Tumor; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Microsomes, Liver; Models, Biological; Models, Molecular; Retinoic Acid 4-Hydroxylase; Stereoisomerism; Structure-Activity Relationship; Tetralones; Tretinoin | 2005 |
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship | 2010 |
Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): synthesis and biological evaluation.
Topics: Antineoplastic Agents; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Cytochrome P-450 Enzyme Inhibitors; Heme; Humans; Imidazoles; Inhibitory Concentration 50; Leukemia, Lymphocytic, Chronic, B-Cell; Models, Molecular; Sequence Homology, Amino Acid; Structure-Activity Relationship; Vitamin D3 24-Hydroxylase | 2014 |
R 75251, a new inhibitor of steroid biosynthesis.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Androgen Antagonists; Animals; Estradiol; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Male; Middle Aged; Rats; Steroids; Testosterone | 1990 |
Effects of cytochrome P-450 inhibitors on the in vivo metabolism of all-trans-retinoic acid in rats.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Imidazoles; Ketoconazole; Male; Rats; Rats, Inbred Strains; Tretinoin | 1990 |
The effects of a new imidazole derivative in advanced prostatic cancer. A preliminary report.
Topics: Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers, Tumor; Humans; Imidazoles; Ketoconazole; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms | 1989 |
Enhancement of antiproliferative activity of 1alpha,25-dihydroxyvitamin D3 (analogs) by cytochrome P450 enzyme inhibitors is compound- and cell-type specific.
Topics: Calcitriol; Cell Division; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Tumor Cells, Cultured | 1996 |
Novel nonsteroidal inhibitor of cytochrome P450(17alpha) (17alpha-hydroxylase/C17-20 lyase), YM116, decreased prostatic weights by reducing serum concentrations of testosterone and adrenal androgens in rats.
Topics: Abiraterone Acetate; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Androstadienes; Animals; Carbazoles; Enzyme Inhibitors; Gonadotropin-Releasing Hormone; Guinea Pigs; Imidazoles; Ketoconazole; Male; Orchiectomy; Organ Size; Prostate; Rats; Seminal Vesicles; Steroid 17-alpha-Hydroxylase; Testosterone | 1998 |
Embryonal carcinoma cell lines stably transfected with mRARbeta2-lacZ: sensitive system for measuring levels of active retinoids.
Topics: Animals; Carcinoma, Embryonal; Chick Embryo; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation, Developmental; Genes, Reporter; Imidazoles; Isomerism; Ketoconazole; Limb Buds; Mesoderm; Mice; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoids; Time Factors; Transcriptional Activation; Transfection; Tretinoin; Tumor Cells, Cultured | 1999 |