lgd-2226 and bicalutamide

lgd-2226 has been researched along with bicalutamide* in 1 studies

Other Studies

1 other study(ies) available for lgd-2226 and bicalutamide

Article	Year
Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones. Bioorganic & medicinal chemistry letters, 2007, Mar-15, Volume: 17, Issue:6 A series of alkylamino-2-quinolinone compounds (3) was discovered as androgen receptor modulators based on an early linear tricyclic quinoline pharmacophore (1). The series demonstrated selective high binding affinity to androgen receptor and potent receptor modulating activities in the cotransfection assays. Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Cell Line; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nitriles; Quinolines; Receptors, Androgen; Structure-Activity Relationship; Tosyl Compounds; Transfection	2007

Article

Year

Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones.

Bioorganic & medicinal chemistry letters, 2007, Mar-15, Volume: 17, Issue:6

A series of alkylamino-2-quinolinone compounds (3) was discovered as androgen receptor modulators based on an early linear tricyclic quinoline pharmacophore (1). The series demonstrated selective high binding affinity to androgen receptor and potent receptor modulating activities in the cotransfection assays.

Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Cell Line; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nitriles; Quinolines; Receptors, Androgen; Structure-Activity Relationship; Tosyl Compounds; Transfection

2007