lexitropsin has been researched along with stallimycin in 9 studies
| Studies (lexitropsin) | Trials (lexitropsin) | Recent Studies (post-2010) (lexitropsin) | Studies (stallimycin) | Trials (stallimycin) | Recent Studies (post-2010) (stallimycin) |
|---|---|---|---|---|---|
| 73 | 0 | 3 | 485 | 0 | 39 |
| Protein | Taxonomy | lexitropsin (IC50) | stallimycin (IC50) |
|---|---|---|---|
| GTPase HRas | Homo sapiens (human) | 0.2 | |
| Estrogen receptor | Homo sapiens (human) | 0.02 | |
| Neutrophil elastase | Homo sapiens (human) | 0.2 | |
| DNA topoisomerase 1 | Homo sapiens (human) | 2.7 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lown, JW | 1 |
| Brazil-Zison, M; Dickerson, RE; Filipowsky, ME; Kopka, ML; Lown, JW | 1 |
| Dickerson, RE; Goodsell, DS; Kopka, ML; Walker, WL | 1 |
| Lown, JW; Mazumder, A; Neamati, N; Owen, JM; Pommier, Y; Sunder, S; Tandon, M | 1 |
| Bartulewicz, D; Markowska, A; Pućkowska, A; Rózański, A; Zwierz, K | 1 |
| Lown, JW; Reddy, BS; Sharma, SK | 1 |
| Goodsell, DS | 1 |
| Denny, WA | 1 |
| Markowska, A; Rózański, A | 1 |
4 review(s) available for lexitropsin and stallimycin
| Article | Year |
|---|---|
DNA recognition by lexitropsins, minor groove binding agents.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Base Sequence; Binding Sites; Distamycins; DNA; Drug Design; Electrochemistry; Humans; Ligands; Models, Biological; Molecular Sequence Data; Molecular Structure; Netropsin; Nucleic Acid Conformation | 1994 |
Recent developments in sequence selective minor groove DNA effectors.
Topics: Animals; Anthraquinones; Benzimidazoles; Bisbenzimidazole; Bleomycin; Chemistry, Pharmaceutical; Cross-Linking Reagents; Distamycins; DNA; Drug Design; Duocarmycins; Humans; Indoles; Leucomycins; Ligands; Netropsin; Urea | 2001 |
Sequence recognition of DNA by lexitropsins.
Topics: Base Pairing; Crystallography, X-Ray; Distamycins; DNA; Drug Design; Models, Chemical; Models, Molecular; Netropsin | 2001 |
DNA minor groove alkylating agents.
Topics: Alkylating Agents; Animals; Anthramycin; Antibiotics, Antineoplastic; Benzofurans; Bisbenzimidazole; Chlorambucil; Cyclohexanecarboxylic Acids; Cyclohexenes; Distamycins; DNA; Duocarmycins; Humans; Indoles; Netropsin; Nitrogen Mustard Compounds; Pyrroles; Structure-Activity Relationship | 2001 |
5 other study(ies) available for lexitropsin and stallimycin
| Article | Year |
|---|---|
Linked lexitropsins and the in vitro inhibition of HIV-1 reverse transcriptase RNA-directed DNA polymerization: a novel induced-fit of 3,5 m-pyridyl bisdistamycin to enzyme-associated template-primer.
Topics: Antiviral Agents; Bisbenzimidazole; Diminazene; Distamycins; DNA Polymerase I; DNA Primers; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; Indoles; Kinetics; Models, Molecular; Netropsin; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides | 1996 |
Design of stapled DNA-minor-groove-binding molecules with a mutable atom simulated annealing method.
Topics: Base Sequence; Binding Sites; Distamycins; DNA; Entropy; Hydrogen Bonding; Hydroxides; Netropsin; Structure-Activity Relationship | 1997 |
Highly potent synthetic polyamides, bisdistamycins, and lexitropsins as inhibitors of human immunodeficiency virus type 1 integrase.
Topics: Anti-HIV Agents; Base Sequence; Cells, Cultured; Distamycins; DNA Footprinting; HIV Integrase; HIV Integrase Inhibitors; Humans; Molecular Sequence Data; Netropsin; Nylons; Repetitive Sequences, Nucleic Acid; Sequence Alignment; Structure-Activity Relationship | 1998 |
Synthetic analogues of netropsin and distamycin. V. Synthesis of a carbocyclic bis-lexitropsin as potential DNA cleaving agent.
Topics: Antineoplastic Agents; Antiviral Agents; Cell Division; Distamycins; Humans; Netropsin | 1999 |
Synthetic analogues of netropsin and distamycin. VI. Synthesis of carbocyclic lexitropsins containing a bioreductive element.
Topics: Alkylation; Antineoplastic Agents; Cell Hypoxia; Distamycins; DNA, Neoplasm; Netropsin; Oxidation-Reduction | 2000 |