levoleucovorin has been researched along with sulforaphane* in 1 studies
1 other study(ies) available for levoleucovorin and sulforaphane
| Article | Year |
|---|---|
Sulforaphane has an additive anticancer effect to FOLFOX in highly metastatic human colon carcinoma cells.
Colorectal cancer (CRC) is one of the most common malignancies worldwide. Patients with CRC may need chemotherapy (CTx) in a neoadjuvant, adjuvant or palliative setting through the course of the disease. Unfortunately, its effect is limited by chemoresistance and chemotoxicity. Novel more effective and non‑toxic CTx regimens are needed to further improve CRC treatment outcomes. Thus, the present study was designed to test the hypothesis that non‑toxic sulforaphane (SF) is effective against CRC and has additive effects in combination with conventional 5‑fluorouracil, oxaliplatin and folinic acid (FOLFOX) CTx Topics: Aldehyde Dehydrogenase 1 Family; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Fluorouracil; Humans; Isothiocyanates; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Sulfoxides | 2022 |