Compounds > levofloxacin
Page last updated: 2024-09-04

levofloxacin and zopiclone

levofloxacin has been researched along with zopiclone in 4 studies

Compound Research Comparison

Studies
(levofloxacin)		Trials
(levofloxacin)		Recent Studies (post-2010)
(levofloxacin)		Studies
(zopiclone)		Trials
(zopiclone)		Recent Studies (post-2010) (zopiclone)
4,3465812,209747204184

Protein Interaction Comparison

ProteinTaxonomylevofloxacin (IC50)zopiclone (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.029
GABA theta subunitRattus norvegicus (Norway rat)0.029
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.029

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Other Studies

4 other study(ies) available for levofloxacin and zopiclone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013