levofloxacin has been researched along with vinblastine in 8 studies
| Studies (levofloxacin) | Trials (levofloxacin) | Recent Studies (post-2010) (levofloxacin) | Studies (vinblastine) | Trials (vinblastine) | Recent Studies (post-2010) (vinblastine) |
|---|---|---|---|---|---|
| 4,346 | 581 | 2,209 | 243 | 0 | 77 |
| Protein | Taxonomy | levofloxacin (IC50) | vinblastine (IC50) |
|---|---|---|---|
| Tubulin alpha-1A chain | Sus scrofa (pig) | 1.1 | |
| Tubulin beta chain | Sus scrofa (pig) | 1.1 | |
| Tubulin beta-4A chain | Homo sapiens (human) | 0.8233 | |
| Cholinesterase | Homo sapiens (human) | 2.1 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 8 | |
| Tubulin beta chain | Homo sapiens (human) | 0.8233 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 6 | |
| Tubulin alpha-3C chain | Homo sapiens (human) | 0.8233 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.6 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 5.037 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 2.1 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 2.1 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 2.1 | |
| Thromboxane-A synthase | Homo sapiens (human) | 1.87 | |
| Tubulin alpha-1B chain | Homo sapiens (human) | 0.8233 | |
| Tubulin alpha-4A chain | Homo sapiens (human) | 0.8233 | |
| Tubulin beta-4B chain | Homo sapiens (human) | 0.8233 | |
| Tubulin beta-3 chain | Homo sapiens (human) | 0.8233 | |
| Tubulin beta-2A chain | Homo sapiens (human) | 0.8233 | |
| Beta-tubulin | Leishmania donovani | 1 | |
| Tubulin beta-8 chain | Homo sapiens (human) | 0.8233 | |
| Tubulin beta-2B chain | Bos taurus (cattle) | 0.65 | |
| Tubulin alpha-3E chain | Homo sapiens (human) | 0.8233 | |
| Tubulin alpha-1A chain | Homo sapiens (human) | 0.8233 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 0.65 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 0.65 | |
| Tubulin alpha-1C chain | Homo sapiens (human) | 0.8233 | |
| Tubulin beta-6 chain | Homo sapiens (human) | 0.8233 | |
| Tubulin beta-2B chain | Homo sapiens (human) | 0.8233 | |
| Tubulin beta-1 chain | Homo sapiens (human) | 0.8233 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gibbons, S; Kaatz, GW; Zloh, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
1 review(s) available for levofloxacin and vinblastine
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
7 other study(ies) available for levofloxacin and vinblastine
| Article | Year |
|---|---|
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |