levofloxacin has been researched along with trazodone in 8 studies
| Studies (levofloxacin) | Trials (levofloxacin) | Recent Studies (post-2010) (levofloxacin) | Studies (trazodone) | Trials (trazodone) | Recent Studies (post-2010) (trazodone) |
|---|---|---|---|---|---|
| 4,346 | 581 | 2,209 | 1,466 | 295 | 312 |
| Protein | Taxonomy | levofloxacin (IC50) | trazodone (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.091 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.909 | |
| D(2) dopamine receptor | Homo sapiens (human) | 4.485 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.017 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.281 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.389 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.942 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.311 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.281 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.265 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.1315 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.091 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.311 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.192 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.361 | |
| D(3) dopamine receptor | Homo sapiens (human) | 3.743 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.107 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.281 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 2.203 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for levofloxacin and trazodone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
7 other study(ies) available for levofloxacin and trazodone
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |