Compounds > levofloxacin
Page last updated: 2024-09-04

levofloxacin and sulbactam

levofloxacin has been researched along with sulbactam in 16 studies

Compound Research Comparison

Studies
(levofloxacin)		Trials
(levofloxacin)		Recent Studies (post-2010)
(levofloxacin)		Studies
(sulbactam)		Trials
(sulbactam)		Recent Studies (post-2010) (sulbactam)
4,3465812,2091,844297488

Protein Interaction Comparison

ProteinTaxonomylevofloxacin (IC50)sulbactam (IC50)
Beta-lactamase Escherichia coli6.2
Beta-lactamase Shouchella clausii0.075
Beta-lactamase Pseudomonas aeruginosa0.37
Beta-lactamase Pseudomonas aeruginosa3
Beta-lactamase Aeromonas allosaccharophila4
Beta-lactamaseStaphylococcus aureus6.5
Beta-lactamaseEnterobacter cloacae1.4
Beta-lactamase TEMEscherichia coli4.3
Beta-lactamase Acinetobacter pittii1.12
Beta-lactamase Acinetobacter pittii7.758
Beta-lactamase Pseudomonas aeruginosa3
Beta-lactamase Escherichia coli2.4

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's9 (56.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Karasawa, T; Kuriyama, T; Nakagawa, K; Nakamura, S; Yamamoto, E1
Furugo, I; Ishida, M; Takii, M; Ueda, M1
Arenoso, H; Bantar, C; Caruso, N; Fernández Canigia, L; Nicola, F; Soutric, J1
Fang, X; Gong, M; Xia, J; Xu, Y; Zhang, D; Zhou, Y1
Li, J; Liu, Y; Wei, W; Yang, H; Ye, Y1
Badal, RE; Cao, B; Chen, S; Chu, Y; Duan, Q; Feng, X; Gui, B; Hu, B; Hu, Z; Huang, W; Kong, H; Liao, K; Luo, Y; Ni, Y; Shao, H; Su, J; Sun, Z; Wang, Y; Wu, A; Xu, Y; Yang, Q; Yu, Y; Zhang, H; Zhang, S1
Aksaray, S; Avcıküçük, H; Başustaoğlu, A; Kaşkatepe, B; Süzük, S1
Gao, L; Li, Y; Lyu, Y1
Ejaz, A; Ejaz, H; Javed, H; Saleem, R; Younas, S; Zafar, A1
Li, LJ; Wang, DL; Zhao, LD; Zhou, MJ1
Hu, S; Lou, Z; Shen, Y; Tu, M1
Mo, L; Peng, M; Qian, J; Wang, J1

Reviews

1 review(s) available for levofloxacin and sulbactam

ArticleYear
Bacteriological Studies of Venomous Snakebite Wounds in Hangzhou, Southeast China.
    The American journal of tropical medicine and hygiene, 2022, 10-12, Volume: 107, Issue:4

    Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacteria; Cefazolin; Cefoxitin; Ciprofloxacin; Clavulanic Acid; Fluoroquinolones; Humans; Levofloxacin; Microbial Sensitivity Tests; Snake Bites; Sulbactam; Venoms

2022

Trials

1 trial(s) available for levofloxacin and sulbactam

ArticleYear
An ex-vivo pharmacodynamic study comparing bactericidal activity of amoxicillin/sulbactam, azithromycin, doxycycline and levofloxacin against Streptococcus pneumoniae.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16, Issue:3

    Topics: Adult; Amoxicillin; Analysis of Variance; Azithromycin; Blood Bactericidal Activity; Colony Count, Microbial; Cross-Over Studies; Doxycycline; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Probability; Sensitivity and Specificity; Serum Bactericidal Test; Single-Blind Method; Statistics, Nonparametric; Streptococcus pneumoniae; Sulbactam

2004

Other Studies

14 other study(ies) available for levofloxacin and sulbactam

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections.
    Oral microbiology and immunology, 2002, Volume: 17, Issue:2

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Cefazolin; Cefotaxime; Cephalosporins; Clindamycin; Corynebacterium; Drug Resistance, Bacterial; Erythromycin; Eubacterium; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Imipenem; Levofloxacin; Ofloxacin; Penicillins; Peptostreptococcus; Periodontitis; Staphylococcus; Streptococcus; Sulbactam; Thienamycins; Tooth Diseases

2002
[Microbiological and clinical studies of Haemophilus influenzae isolated at Kitakyushu Municipal Medical Center from 1996 through 1999].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3

    Topics: Adult; Aged; Ampicillin; Anti-Infective Agents; beta-Lactamases; Cefaclor; Cephalosporins; Child, Preschool; Female; Haemophilus influenzae; Humans; Imipenem; Infant; Infant, Newborn; Levofloxacin; Male; Meningitis, Bacterial; Meropenem; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Respiratory System; Seasons; Sulbactam; Thienamycins

2002
A retrospective analysis of carbapenem-resistant Acinetobacter baumannii-mediated nosocomial pneumonia and the in vitro therapeutic benefit of cefoperazone/sulbactam.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 23

    Topics: Acinetobacter baumannii; Aged; Aged, 80 and over; Anti-Bacterial Agents; C-Reactive Protein; Carbapenems; Cefoperazone; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Female; Humans; Levofloxacin; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Minocycline; Pneumonia, Bacterial; Retrospective Studies; Sulbactam; Thienamycins

2014
In vitro synergy of colistin combinations against extensively drug-resistant Acinetobacter baumannii producing OXA-23 carbapenemase.
    Journal of chemotherapy (Florence, Italy), 2016, Volume: 28, Issue:3

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Colistin; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Fosfomycin; Humans; Imipenem; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Polymerase Chain Reaction; Rifampin; Sulbactam

2016
Antimicrobial Susceptibilities of Aerobic and Facultative Gram-Negative Bacilli from Intra-abdominal Infections in Patients from Seven Regions in China in 2012 and 2013.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1

    Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefoxitin; China; Ciprofloxacin; Community-Acquired Infections; Cross Infection; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Gene Expression; Humans; Imipenem; Intraabdominal Infections; Levofloxacin; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam

2016
[The comparison of antibiotic susceptibilities of uropathogenic Escherichia coli isolates in transition from CLSI to EUCAST].
    Mikrobiyoloji bulteni, 2015, Volume: 49, Issue:4

    Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Bacteriuria; Cefuroxime; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Drug Resistance, Bacterial; Escherichia coli Infections; European Union; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Reference Standards; Sulbactam; Trimethoprim, Sulfamethoxazole Drug Combination; Turkey; Urinary Tract Infections; Uropathogenic Escherichia coli

2015
Trends in Drug Resistance of
    Chinese medical journal, 2017, Mar-20, Volume: 130, Issue:6

    Topics: Acinetobacter baumannii; Amikacin; Anti-Infective Agents; Cefepime; Cefoperazone; Ceftazidime; Cephalosporins; China; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam

2017
AmpC beta-lactamases in Klebsiella pneumoniae: An emerging threat to the paediatric patients.
    JPMA. The Journal of the Pakistan Medical Association, 2018, Volume: 68, Issue:6

    Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefoperazone; Cefoxitin; Cephalosporins; Child; Child, Preschool; Ciprofloxacin; Cross-Sectional Studies; Disk Diffusion Antimicrobial Tests; Drug Combinations; Drug Resistance, Bacterial; Female; Hospitals, Pediatric; Humans; Imipenem; Infant; Infant, Newborn; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Male; Meropenem; Microbial Sensitivity Tests; Pakistan; Piperacillin, Tazobactam Drug Combination; Sulbactam

2018
Septic shock caused by Rhizobium radiobacter in an elderly woman: A case report.
    Medicine, 2019, Volume: 98, Issue:49

    Topics: Aged, 80 and over; Agrobacterium tumefaciens; Anti-Bacterial Agents; Cefoperazone; Disease Progression; Drug Therapy, Combination; Female; Humans; Levofloxacin; Shock, Septic; Sulbactam

2019
Antibiotic Sensitivity of
    International journal of clinical practice, 2022, Volume: 2022

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cefoperazone; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Proteus Infections; Proteus mirabilis; Sulbactam; Sulfamethoxazole; Urinary Calculi; Urinary Tract Infections

2022