Page last updated: 2024-09-04

levofloxacin and pyrazinamide

levofloxacin has been researched along with pyrazinamide in 55 studies

Compound Research Comparison

Studies (levofloxacin)	Trials (levofloxacin)	Recent Studies (post-2010) (levofloxacin)	Studies (pyrazinamide)	Trials (pyrazinamide)	Recent Studies (post-2010) (pyrazinamide)
4,346	581	2,209	3,626	320	1,113

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (3.64)	18.2507
2000's	8 (14.55)	29.6817
2010's	33 (60.00)	24.3611
2020's	12 (21.82)	2.80

Authors

Authors	Studies
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Khanna, A; Pareek, PK; Raj, VS; Rattan, A; Saini, KS; Sharma, P; Singh, H; Sood, R; Tarai, B; Upadhyay, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bera, S; Mondal, D	1
Mabhula, A; Singh, V	1
Chirgwin, K; El Sadr, WM; Hafner, R; Heifets, LB; Klein, O; Kreiswirth, BN; Matts, JP; Musser, JM; Nelson, ET; Perlman, DC; Salomon, N; Telzak, EE	1
Chirgwin, KD; Cohn, DL; el-Sadr, WM; Hafner, R; Heifets, L; Jones, BE; Klein, O; Matts, JP; Medard, F; Mildvan, D; Nelson, ET; Olibrice, M; Perlman, DC; Salomon, N; Telzak, EE	1
Cheon, SH; Dietze, R; Ellner, JJ; Hise, AG; Landen, K; Palaci, M; Phillips, M; Ribeiro, FC; Song, HY; Vinhas, S; Wallis, RS	1
Lou, HX; McKaveney, TP; Shullo, MA	1
Dolovich, LR; Holbrook, A; Loeb, M; Papastavros, T; Whitehead, L	1
Bogadel'nikova, IV; Kunichan, AD; Semenova, OV; Sokolova, GB	1
Aguilar, R; Auclair, B; Maslow, JN; Mikota, SK; Peloquin, CA	1
Kunichan, AD; Litovchenko, KV; Sokolova, GB; Tsybanev, AA	1
Chen, L; Chen, QL; Yin, JJ	1
Caminero, JA; Migliori, GB; Sotgiu, G; Zumla, A	1
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA	1
Akçalı, A; Akman, T; Değirmenci, Y; Karatağ, O; Koşar, S; Sener, A	1
Bergmann, JF; Cambau, E; Evans, J; Hoang-Nguyen, DT; Lloret-Linares, C; Lopes, A; Mouly, S; Raskine, L; Sellier, P	1
Ahmad, Z; Grosset, JH; Minkowski, A; Nuermberger, EL; Peloquin, CA; Tyagi, S	1
Chikamatsu, K; Fujita, A; Matsumoto, T; Mitarai, S; Mizuno, K; Ogata, H; Saito, T; Suetake, T; Suzuki, K; Toyota, E	1
Chandrasekaran, V; Dewan, P; Hemanth Kumar, AK; Ramachandran, G; Swaminathan, S; Thomas, A	1
Gratz, J; Heysell, SK; Houpt, ER; Kibiki, GS; Kumburu, H; Mpagama, SG; Ndusilo, N; Peloquin, CA; Stroup, S	1
Adler-Shohet, FC; Carson, M; Girma, H; Low, J; Singh, J	1
Bhoi, SK; Kalita, J; Misra, UK; Prasad, S	1
Bharti, H; Bhushan, B; Chander, R; Gupta, A; Kajal, NC; Ranga, V	1
Arai, M	1
Chung, JY; Jang, IJ; Jang, K; Lee, JH; Moon, SJ; Oh, J; Park, JS; Park, SI; Song, J; Yoon, J; Yu, KS	1
Betai, S; Bhoi, SK; Kalita, J; Misra, UK	1
Jung, JA; Kaisar, N; Parvez, MM; Shin, HJ; Shin, JG	1
Juthong, S; Laohapojanart, N; Padmavathi, AR; Pungrassami, P; Ratanajamit, C; Srichana, T; Suwandecha, T	1
Adebola, SO; Adedeji, TO; Adefuye, BO; Oladeji, SM; Sogebi, OA	1
Khanna, SR; Kralovic, SM; Prakash, R	1
Boulle, A; Fox, T; Khomo, N; Kock, Y; Leslie, J; Manning, K; Meintjes, G; Mudaly, V; Stewart, A; Tiffin, N; Wasserman, S; Zhao, Y	1
Patel, S; Roy, S; Weaver, MD	1
Alarcón Guizado, VA; Alarcon, E; Cornejo Garcia, JG; Heldal, E; Mendoza Ticona, A; Moore, DAJ	1
Ahn, H; Ahn, JH; Cho, SN; Hahn, S; Jang, JY; Jeon, D; Jhun, BW; Jo, KW; Kang, YA; Kim, CK; Kim, DK; Kim, JS; Kim, SY; Kim, YR; Koh, WJ; Lee, JH; Lee, JY; Lee, M; Lee, SH; Lee, T; Mok, J; Park, JS; Shim, TS; Shin, S; Shin, SJ; Song, T; Won, HJ; Yim, JJ	1
Ader, F; Collardeau-Frachon, S; Gillet, Y; Huguet, A; Ohlmann, C	1
Abbara, A; Abubakar, I; Alexander, E; Booth, H; Bothamley, GH; Creer, DD; Davidson, JA; Harris, RJ; Kon, OM; Kunst, H; Lalor, MK; Lipman, MC; Loebinger, MR; Loutet, MG; Lozewicz, S; McHugh, TD; Milburn, HJ; Mohiyuddin, T; Palchaudhuri, P; Phillips, PPJ; Schmok, E; Stagg, HR; Taylor, L	1
E R, V; Keny, S; Lawande, D; Parrikar, A	1
Baloch, AQ; Ghazal, A; Khanzada, FM; Mustafa, T; Qadir, M; Rizvi, AH; Tahseen, S	1
Eather, G; Matigian, N; O'Connor, B; Wilson, M	1
Ishikawa, S; Mukai, Y; Paudel, S; Suga, S; Wada, T; Yoshida, S	1
Kawkitinarong, K; Laohapojanart, N; Ratanajamit, C; Srichana, T	1
Bate, PNN; Chiwala, G; Fang, C; Guan, P; Hameed, HMA; Hu, J; Khan, SA; Liu, J; Liu, Z; Mugweru, JN; Tan, S; Tan, Y; Wang, B; Yusuf, B; Zhang, T; Zhong, N	1
Jiang, H; Li, X; Niu, Q; Xing, Z; Xu, J	1
Chen, KH; Chen, YL; Hung, CC; Lin, SW; Liu, WD; Wang, JT; Wang, YC	1
Kamoshita, F; Karaushi, H; Mitsutake, K; Miyawaki, Y; Seki, M; Watanabe, N	1
Brankin, A; Colman, RE; Georghiou, SB; Seifert, M; Suresh, A; Uplekar, S; Walker, TM	1
Ahn, JH; Cho, SN; Hahn, S; Jeon, D; Jhun, BW; Jo, KW; Kang, YA; Kim, DK; Kim, J; Kim, JS; Kim, K; Kim, S; Kim, SY; Kim, YR; Kwak, N; Lee, JK; Lee, JY; Lee, M; Lee, SH; Lee, T; Mok, J; Park, JS; Seok, KH; Shim, TS; Yim, D; Yim, JJ; Yoon, S	1
Aalhoul, F; Cotton, F; Fage, D	1

Reviews

4 review(s) available for levofloxacin and pyrazinamide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Insights of synthetic analogues of anti-leprosy agents. Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13 Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship	2019
Drug-resistance in MedChemComm, 2019, Aug-01, Volume: 10, Issue:8 Topics:	2019
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis. The Lancet. Infectious diseases, 2010, Volume: 10, Issue:9 Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; Kanamycin; Levofloxacin; Ofloxacin; Pyrazinamide; Tuberculosis	2010

Trials

11 trial(s) available for levofloxacin and pyrazinamide

Article	Year
Susceptibility to levofloxacin of Myocobacterium tuberculosis isolates from patients with HIV-related tuberculosis and characterization of a strain with levofloxacin monoresistance. Community Programs for Clinical Research on AIDS 019 and the AIDS Clinica AIDS (London, England), 1997, Volume: 11, Issue:12 Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antibiotics, Antitubercular; Antitubercular Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Ethambutol; Humans; In Vitro Techniques; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin; Sputum; Tuberculosis	1997
Evaluation of an intensive intermittent-induction regimen and duration of short-course treatment for human immunodeficiency virus-related pulmonary tuberculosis. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) and the AIDS Clinical Tr Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:5 Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Recurrence; Rifampin; Sputum; Treatment Outcome; Tuberculosis, Pulmonary	1998
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7 Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult	2011
Safety and efficacy of levofloxacin versus rifampicin in tuberculous meningitis: an open-label randomized controlled trial. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8 Topics: Adolescent; Adult; Aged; Antitubercular Agents; Aspirin; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Prednisolone; Pyrazinamide; Radiography; Rifampin; Treatment Outcome; Tuberculosis, Meningeal; Young Adult	2014
Pharmacokinetics of Second-Line Antituberculosis Drugs after Multiple Administrations in Healthy Volunteers. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Area Under Curve; Cycloserine; Drug Monitoring; Fluoroquinolones; Healthy Volunteers; Humans; Kanamycin; Levofloxacin; Male; Moxifloxacin; Prothionamide; Pyrazinamide; Streptomycin; Young Adult	2015
Safety and efficacy of additional levofloxacin in tuberculous meningitis: A randomized controlled pilot study. Tuberculosis (Edinburgh, Scotland), 2016, Volume: 98 Topics: Adolescent; Adult; Aged; Antitubercular Agents; Disability Evaluation; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Pilot Projects; Proportional Hazards Models; Pyrazinamide; Rifampin; Seizures; Time Factors; Treatment Outcome; Tuberculosis, Meningeal; Young Adult	2016
Evaluation of Proinflammatory Cytokines and Adverse Events in Healthy Volunteers upon Inhalation of Antituberculosis Drugs. Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:11 Topics: Administration, Inhalation; Adult; Antitubercular Agents; Cross-Over Studies; Double-Blind Method; Dry Powder Inhalers; Female; Healthy Volunteers; Humans; Interleukin-1beta; Isoniazid; Levofloxacin; Liposomes; Male; Peak Expiratory Flow Rate; Pyrazinamide; Rifampin; Sputum; Tumor Necrosis Factor-alpha; Young Adult	2016
Treatment outcomes for isoniazid-monoresistant tuberculosis in Peru, 2012-2014. PloS one, 2018, Volume: 13, Issue:12 Topics: Adolescent; Adult; Child; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Ethambutol; Female; Humans; Infant; Infant, Newborn; Isoniazid; Levofloxacin; Male; Middle Aged; Peru; Pyrazinamide; Retrospective Studies; Rifampin; Sex Factors; Time Factors; Tuberculosis, Multidrug-Resistant	2018
Delamanid, linezolid, levofloxacin, and pyrazinamide for the treatment of patients with fluoroquinolone-sensitive multidrug-resistant tuberculosis (Treatment Shortening of MDR-TB Using Existing and New Drugs, MDR-END): study protocol for a phase II/III, m Trials, 2019, Jan-16, Volume: 20, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Equivalence Trials as Topic; Female; Humans; Levofloxacin; Linezolid; Male; Middle Aged; Multicenter Studies as Topic; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Republic of Korea; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Young Adult	2019
Efficacy and safety of combined isoniazid-rifampicin-pyrazinamide-levofloxacin dry powder inhaler in treatment of pulmonary tuberculosis: A randomized controlled trial. Pulmonary pharmacology & therapeutics, 2021, Volume: 70 Topics: Dry Powder Inhalers; Humans; Isoniazid; Levofloxacin; Powders; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary	2021
9 months of delamanid, linezolid, levofloxacin, and pyrazinamide versus conventional therapy for treatment of fluoroquinolone-sensitive multidrug-resistant tuberculosis (MDR-END): a multicentre, randomised, open-label phase 2/3 non-inferiority trial in So Lancet (London, England), 2022, 10-29, Volume: 400, Issue:10362 Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Male; Pyrazinamide; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2022

Other Studies

40 other study(ies) available for levofloxacin and pyrazinamide

Article	Year
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysis; DNA-Directed RNA Polymerases; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; India; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Point Mutation; Polymerase Chain Reaction; Rifampin	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
A whole blood bactericidal assay for tuberculosis. The Journal of infectious diseases, 2001, Apr-15, Volume: 183, Issue:8 Topics: Anti-Infective Agents; Antitubercular Agents; Aza Compounds; Blood; Blood Bactericidal Activity; Culture Media; Ethambutol; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Quinolines; Rifampin	2001
Limited tolerability of levofloxacin and pyrazinamide for multidrug-resistant tuberculosis prophylaxis in a solid organ transplant population. Pharmacotherapy, 2002, Volume: 22, Issue:6 Topics: Anti-Infective Agents; Antitubercular Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Levofloxacin; Male; Middle Aged; Ofloxacin; Organ Transplantation; Pyrazinamide; Retrospective Studies; Transplantation Immunology; Tuberculosis	2002
Adverse events associated with pyrazinamide and levofloxacin in the treatment of latent multidrug-resistant tuberculosis. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002, Jul-23, Volume: 167, Issue:2 Topics: Adolescent; Adult; Anti-Infective Agents; Antitubercular Agents; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyrazinamide; Tuberculosis, Multidrug-Resistant	2002
[Effect of levofloxacine on cell elements of the lung tissue and on the growth of drug resistant Mycobacteria tuberculosis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:6 Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Cell Movement; Culture Techniques; Drug Interactions; Drug Resistance, Multiple, Bacterial; Isoniazid; Levofloxacin; Lung; Lymphocytes; Macrophages; Mice; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin	2002
Population pharmacokinetics of antituberculous drugs and treatment of Mycobacterium bovis infection in bongo antelope (Tragelaphus eurycerus isaaci). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2002, Volume: 33, Issue:3 Topics: Amikacin; Animals; Antelopes; Antitubercular Agents; Area Under Curve; Ethambutol; Female; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Pyrazinamide; Rifampin; Tuberculosis	2002
[Evaluation of levofloxacin antitubercular activity in vitro and in lung tissue culture]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:12 Topics: Anti-Infective Agents; Antitubercular Agents; Drug Therapy, Combination; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide	2002
[A study on the clinical efficacy of a combination regimen with levofloxacin and capreomycin in the treatment of multi-drug resistant pulmonary tuberculosis]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2003, Volume: 26, Issue:8 Topics: Adolescent; Adult; Antitubercular Agents; Capreomycin; Drug Therapy, Combination; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2003
[Epidural abscess due to a Mycobacterium tuberculosis strain with primary resistance to isoniazid and ethambutol]. Mikrobiyoloji bulteni, 2012, Volume: 46, Issue:4 Topics: Antitubercular Agents; Cervical Vertebrae; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Epidural Abscess; Ethambutol; Humans; Isoniazid; Levofloxacin; Magnetic Resonance Imaging; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Streptomycin; Thoracic Vertebrae; Tuberculosis, Central Nervous System	2012
Inadequate therapeutic response to a recommended antituberculosis fixed-dose combination regimen in an overweight patient with Mycobacterium bovis infection. The Annals of pharmacotherapy, 2013, Volume: 47, Issue:1 Topics: Adult; Antitubercular Agents; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Humans; Isoniazid; Levofloxacin; Male; Mycobacterium bovis; Ofloxacin; Overweight; Practice Guidelines as Topic; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Lymph Node	2013
Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis. American journal of respiratory and critical care medicine, 2013, Jul-01, Volume: 188, Issue:1 Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoroquinolones; Levofloxacin; Mice; Mice, Inbred BALB C; Moxifloxacin; Ofloxacin; Pyrazinamide; Quinolines; Treatment Outcome; Tuberculosis	2013
[Clinical evaluation of a line probe assay kit for the identification of Mycobacterium species and detection of drug-resistant Mycobacterium tuberculosis]. Kekkaku : [Tuberculosis], 2013, Volume: 88, Issue:3 Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Rifampin	2013
Estimation of content of anti-TB drugs supplied at centres of the Revised National TB Control Programme in Tamil Nadu, India. Tropical medicine & international health : TM & IH, 2013, Volume: 18, Issue:9 Topics: Antitubercular Agents; Cycloserine; Drug Stability; Drug Storage; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; India; Isoniazid; Levofloxacin; Ofloxacin; Pyrazinamide; Rifampin; Spectrophotometry; Tuberculosis	2013
Plasma drug activity in patients on treatment for multidrug-resistant tuberculosis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2 Topics: Adolescent; Adult; Amikacin; Antitubercular Agents; Cycloserine; Ethionamide; Female; Fluoroquinolones; Humans; Kanamycin; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Moxifloxacin; Mycobacterium tuberculosis; Ofloxacin; Pyrazinamide; Sputum; Tanzania; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary	2014
Management of latent tuberculosis infection in child contacts of multidrug-resistant tuberculosis. The Pediatric infectious disease journal, 2014, Volume: 33, Issue:6 Topics: Adolescent; Antibiotic Prophylaxis; Antitubercular Agents; Child; Contact Tracing; Humans; Latent Tuberculosis; Levofloxacin; Pyrazinamide; Retrospective Studies; Tuberculosis, Multidrug-Resistant	2014
Profile of adverse drug reactions in drug resistant tuberculosis from Punjab. The Indian journal of tuberculosis, 2014, Volume: 61, Issue:4 Topics: Adolescent; Adult; Aged; Antitubercular Agents; Arthralgia; Ataxia; Chemical and Drug Induced Liver Injury; Child; Cycloserine; Drug Eruptions; Drug Therapy, Combination; Ethambutol; Ethionamide; Female; Gastrointestinal Diseases; Hearing Loss; Humans; Hypothyroidism; India; Kanamycin; Levofloxacin; Male; Middle Aged; Peripheral Nervous System Diseases; Psychoses, Substance-Induced; Pyrazinamide; Severity of Illness Index; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Vision Disorders; Young Adult	2014
[A case of tuberculous meningitis complicated with multiple drug hypersensitivity to antituberculosis agents]. Rinsho shinkeigaku = Clinical neurology, 2015, Volume: 55, Issue:2 Topics: Antitubercular Agents; Drug Hypersensitivity; Drug Therapy, Combination; Ethambutol; Ethionamide; Humans; Immunologic Tests; Isoniazid; Levofloxacin; Lymphocyte Activation; Male; Middle Aged; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis, Meningeal	2015
Inhibitory Interaction Potential of 22 Antituberculosis Drugs on Organic Anion and Cation Transporters of the SLC22A Family. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11 Topics: 1-Methyl-4-phenylpyridinium; Aminosalicylic Acid; Animals; Antitubercular Agents; Ciprofloxacin; HEK293 Cells; Humans; Inhibitory Concentration 50; Ion Transport; Kinetics; Levofloxacin; Linezolid; Metformin; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Pyrazinamide; Rifabutin; Rifampin; Zidovudine	2016
Clinical predictors of aminoglycoside-induced ototoxicity in drug-resistant Tuberculosis patients on intensive therapy. Auris, nasus, larynx, 2017, Volume: 44, Issue:4 Topics: Adult; Age Factors; Aminoglycosides; Antitubercular Agents; Audiometry, Pure-Tone; Body Mass Index; Coinfection; Comorbidity; Cycloserine; Diabetes Mellitus; Female; Hearing Loss; HIV Infections; Humans; Kanamycin; Levofloxacin; Male; Middle Aged; Nigeria; Prospective Studies; Prothionamide; Pyrazinamide; Risk Factors; Time Factors; Tuberculosis, Multidrug-Resistant; Young Adult	2017
Tuberculous Meningitis in an Immunocompetent Host: A Case Report. The American journal of case reports, 2016, Dec-23, Volume: 17 Topics: Antitubercular Agents; Cerebrospinal Fluid; Drug Therapy, Combination; Emigrants and Immigrants; Humans; Immunocompetence; Isoniazid; Levofloxacin; Male; Middle Aged; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Senegal; Treatment Outcome; Tuberculosis, Meningeal; United States	2016
Improved Treatment Outcomes With Bedaquiline When Substituted for Second-line Injectable Agents in Multidrug-resistant Tuberculosis: A Retrospective Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 04-24, Volume: 68, Issue:9 Topics: Adult; Antitubercular Agents; Coinfection; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; HIV; HIV Infections; Humans; Isoniazid; Isoxazoles; Levofloxacin; Male; Mycobacterium tuberculosis; Oxazolidinones; Pyrazinamide; Retrospective Studies; South Africa; Survival Analysis; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2019
Miliary tuberculosis and herpes pharyngitis after a trip to a developing country: dangers of biologics. BMJ case reports, 2018, Oct-02, Volume: 2018 Topics: Adalimumab; Aged, 80 and over; Anti-Bacterial Agents; Antirheumatic Agents; Antitubercular Agents; Arthritis, Rheumatoid; Biological Products; Developing Countries; Diagnosis, Differential; Herpes Simplex; Herpesvirus 1, Human; Humans; India; Isoniazid; Levofloxacin; Lung; Male; Opportunistic Infections; Pharyngitis; Pyrazinamide; Tomography, X-Ray Computed; Travel-Related Illness; Tuberculin Test; Tuberculosis, Miliary; Vitamin B 6	2018
Drug-Induced Fulminant Hepatitis in a Child Treated for Latent Multidrug-Resistant Tuberculosis With Dual Therapy Combining Pyrazinamide and Levofloxacin. The Pediatric infectious disease journal, 2019, Volume: 38, Issue:10 Topics: Antitubercular Agents; Child; Drug Therapy, Combination; Humans; Latent Tuberculosis; Levofloxacin; Male; Massive Hepatic Necrosis; Pyrazinamide; Tuberculosis, Multidrug-Resistant	2019
Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance. The European respiratory journal, 2019, Volume: 54, Issue:4 Topics: Adolescent; Adult; Aged; Antitubercular Agents; Drug Therapy, Combination; Duration of Therapy; Ethambutol; Female; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Logistic Models; London; Male; Middle Aged; Practice Guidelines as Topic; Pyrazinamide; Recurrence; Retrospective Studies; Rifampin; Treatment Failure; Tuberculosis, Multidrug-Resistant; World Health Organization; Young Adult	2019
Gitelman-like syndrome: A rare complication of using aminoglycosides in tuberculosis - A case report. The Indian journal of tuberculosis, 2020, Volume: 67, Issue:3 Topics: Alkalosis; Antitubercular Agents; Capreomycin; Clofazimine; Cycloserine; Deprescriptions; Ethionamide; Gitelman Syndrome; Humans; Hypocalcemia; Hypokalemia; Levofloxacin; Linezolid; Male; Middle Aged; Pyrazinamide; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Water-Electrolyte Imbalance	2020
Isoniazid resistance profile and associated levofloxacin and pyrazinamide resistance in rifampicin resistant and sensitive isolates/from pulmonary and extrapulmonary tuberculosis patients in Pakistan: A laboratory based surveillance study 2015-19. PloS one, 2020, Volume: 15, Issue:9 Topics: Adolescent; Adult; Antitubercular Agents; Child; Child, Preschool; Drug Resistance, Bacterial; Epidemiological Monitoring; Female; Genotype; Humans; Infant; Isoniazid; Laboratories; Levofloxacin; Male; Microbial Sensitivity Tests; Pakistan; Phenotype; Pyrazinamide; Retrospective Studies; Rifampin; Tuberculosis, Multidrug-Resistant; Young Adult	2020
Management of isoniazid-monoresistant tuberculosis (Hr-TB) in Queensland, Australia: a retrospective case series. Respiratory medicine, 2020, Volume: 173 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Australia; Child; Child, Preschool; Drug Therapy, Combination; Ethambutol; Ethinyl Estradiol-Norgestrel Combination; Female; Fluoroquinolones; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Pyrazinamide; Retrospective Studies; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult	2020
INTENSIVE TREATMENT OF A CAPTIVE BORNEAN ELEPHANT ( Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2021, Volume: 51, Issue:4 Topics: Administration, Rectal; Animals; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Elephants; Isoniazid; Japan; Levofloxacin; Mycobacterium; Mycobacterium Infections; Pyrazinamide	2021
A recombinant selective drug-resistant M. bovis BCG enhances the bactericidal activity of a second-line anti-tuberculosis regimen. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142 Topics: Amikacin; Animals; Antigens, Bacterial; Antitubercular Agents; BCG Vaccine; Disease Models, Animal; Drug Resistance, Bacterial; Levofloxacin; Mice, Inbred BALB C; Mice, SCID; Mycobacterium bovis; Mycobacterium tuberculosis; Plasmids; Prothionamide; Pyrazinamide; Tuberculosis, Pulmonary; Vaccines, Synthetic; Virulence	2021
Intracellular Activity of Poly (DL-Lactide-co-Glycolide) Nanoparticles Encapsulated with Prothionamide, Pyrazinamide, Levofloxacin, Linezolid, or Ethambutol on Multidrug-Resistant Current drug delivery, 2023, Volume: 20, Issue:3 Topics: Anti-Bacterial Agents; Antitubercular Agents; Ethambutol; Humans; Levofloxacin; Linezolid; Mycobacterium tuberculosis; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Prothionamide; Pyrazinamide; Reactive Oxygen Species; Tuberculosis; Tuberculosis, Multidrug-Resistant	2023
Pyrazinamide related prolonged drug-induced liver injury: A case report. Medicine, 2022, Sep-30, Volume: 101, Issue:39 Topics: Antitubercular Agents; Arylamine N-Acetyltransferase; Chemical and Drug Induced Liver Injury; Ethambutol; Humans; Levofloxacin; Pyrazinamide; Transaminases; Tuberculosis, Lymph Node	2022
A Mycobacterium tuberculosis-Infected Patient Who Could Not Tolerate Oral Intake Successfully Treated Using an Intravenous Tedizolid-Containing Regimen. The American journal of case reports, 2022, Oct-10, Volume: 23 Topics: Aged; Anti-Bacterial Agents; Antitubercular Agents; Cutaneous Fistula; Ethambutol; Humans; Isoniazid; Levofloxacin; Linezolid; Male; Meropenem; Micafungin; Mycobacterium tuberculosis; Oxazolidinones; Pyrazinamide; Rifampin; Streptomycin; Teicoplanin; Tetrazoles; Tuberculosis	2022
In silico evaluation of WHO-endorsed molecular methods to detect drug resistant tuberculosis. Scientific reports, 2022, 10-22, Volume: 12, Issue:1 Topics: Amikacin; Antitubercular Agents; Capreomycin; Genotype; Humans; Isoniazid; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; World Health Organization	2022
Protein binding investigation of first-line and second-line antituberculosis drugs. International journal of antimicrobial agents, 2023, Volume: 62, Issue:6 Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Levofloxacin; Linezolid; Moxifloxacin; Protein Binding; Pyrazinamide; Rifampin; Tuberculosis	2023