Page last updated: 2024-09-04

levofloxacin and prednisolone

levofloxacin has been researched along with prednisolone in 24 studies

Compound Research Comparison

Studies
(levofloxacin)
Trials
(levofloxacin)
Recent Studies (post-2010)
(levofloxacin)
Studies
(prednisolone)
Trials
(prednisolone)
Recent Studies (post-2010) (prednisolone)
4,3465812,20934,4143,3027,141

Protein Interaction Comparison

ProteinTaxonomylevofloxacin (IC50)prednisolone (IC50)
Glucocorticoid receptorHomo sapiens (human)0.0278
Progesterone receptorHomo sapiens (human)2.08
Glucocorticoid receptorRattus norvegicus (Norway rat)0.0565
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.016
Mineralocorticoid receptor Homo sapiens (human)0.0322
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.016
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.016
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.016

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (25.00)29.6817
2010's15 (62.50)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Meda, KP; Parmar, C1
Figueira-Coelho, J; Lourenço, S; Malhado, JA; Mendonça, P; Pires, AC1
Bhoi, SK; Kalita, J; Misra, UK; Prasad, S1
Gotoh, M; Katagiri, S; Nakamura, I; Ohyashiki, K; Yoshizawa, S1
Bae, SH; Jin, KW; Kim, E; Kim, H1
Fujikawa, A; Hanazawa, T; Nakamura, H; Okamoto, Y; Yonekura, S1
Ahn, JH; Kim, DH1
Bulut, T; Celik, B; Uzun, R; Yalcin, AD; Yalcin, AN1
Cardoso, L; Gonçalves, JR; Marques, R; Serra, P1
Moussa, K; Schallhorn, JM; Shantha, J1
Cannizzo, P; Dal Vecchio, M; Fea, AM; Grondin, C; Lorenzi, U1
Lehtinen, V; Loukovaara, S; Moilanen, J; Nieminen, R1
Grzybowski, A; Kanclerz, P; Lytvynchuk, L1
Azadi, H; Darabi, E; Fathi, S; Ghanei, M; Ghazale, AH; Ghazvini, A; Izadi, M; Jafari, R; Movaseghi, F; Mozafari, A; Panahi, Y; Parsaei, MR; Ranjkesh, MH; Rezapour, M; Saadat, SH; Salesi, M; Vahedi, E; Zand, N1
Chang, YF; Cheng, YH; Ko, YC; Liu, CJ1

Reviews

2 review(s) available for levofloxacin and prednisolone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Achilles tendon rupture associated with combination therapy of levofloxacin and steroid in four patients and a review of the literature.
    Foot & ankle international, 2007, Volume: 28, Issue:12

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Casts, Surgical; Female; Follow-Up Studies; Glucocorticoids; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Physical Therapy Modalities; Prednisolone; Pulmonary Disease, Chronic Obstructive; Rupture, Spontaneous; Walkers

2007

Trials

1 trial(s) available for levofloxacin and prednisolone

ArticleYear
Safety and efficacy of levofloxacin versus rifampicin in tuberculous meningitis: an open-label randomized controlled trial.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Aspirin; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Levofloxacin; Male; Middle Aged; Prednisolone; Pyrazinamide; Radiography; Rifampin; Treatment Outcome; Tuberculosis, Meningeal; Young Adult

2014

Other Studies

21 other study(ies) available for levofloxacin and prednisolone

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Mycoplasma pneumoniae-associated mucositis with minimal skin manifestations.
    American journal of clinical dermatology, 2008, Volume: 9, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Asthma; Conjunctivitis; Humans; Immunoglobulin G; Immunoglobulin M; Levofloxacin; Lung; Male; Mucositis; Mycoplasma Infections; Mycoplasma pneumoniae; Ofloxacin; Prednisolone; Radiography, Thoracic; Skin Ulcer

2008
[Case report; Disseminated Mycobacterium abscessus infection with hemophagocytic syndrome during treatment of chronic lymphocytic leukemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014, Mar-10, Volume: 103, Issue:3

    Topics: Amikacin; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Clarithromycin; Cyclophosphamide; Humans; Imipenem; Immunocompromised Host; Immunoglobulins, Intravenous; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Levofloxacin; Lymphohistiocytosis, Hemophagocytic; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Opportunistic Infections; Prednisolone; Treatment Outcome

2014
Klebsiella Endophthalmitis as Retinal Vasculitis with Prostatic Abscess.
    Optometry and vision science : official publication of the American Academy of Optometry, 2015, Volume: 92, Issue:7

    Topics: Abscess; Anti-Bacterial Agents; Ceftazidime; Drug Therapy, Combination; Endophthalmitis; Eye Infections, Bacterial; Glucocorticoids; Humans; Intravitreal Injections; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Male; Middle Aged; Prednisolone; Prostatic Diseases; Retinal Vasculitis; Tomography, X-Ray Computed; Visual Acuity; Vitrectomy

2015
Pre-operative effects of the administration of systemic corticosteroids combined with antibiotics on a lobular capillary hemangioma in the nasal cavity.
    Auris, nasus, larynx, 2016, Volume: 43, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Endoscopy; Epistaxis; Female; Glucocorticoids; Granuloma, Pyogenic; Humans; Levofloxacin; Nasal Cavity; Nasal Obstruction; Nasal Surgical Procedures; Nose Diseases; Prednisolone; Preoperative Care; Tomography, X-Ray Computed

2016
Thermal Ocular Surface Injury from Cooking Oil: Delayed Onset Transient Corneal Infiltration and Myopic Shift.
    Korean journal of ophthalmology : KJO, 2016, Volume: 30, Issue:2

    Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Burns, Chemical; Cooking; Corneal Edema; Corneal Stroma; Drug Therapy, Combination; Eye Burns; Glucocorticoids; Humans; Levofloxacin; Male; Myopia; Oils; Ophthalmic Solutions; Prednisolone; Prospective Studies; Vision Disorders; Visual Acuity

2016
Levofloxacin Induced Toxic Epidermal Necrolysis: Successful Therapy with Omalizumab (Anti-IgE) and Pulse Prednisolone.
    The American journal of case reports, 2016, Sep-16, Volume: 17

    Topics: Aged; Anti-Allergic Agents; Anti-Bacterial Agents; Female; Glucocorticoids; Humans; Levofloxacin; Omalizumab; Prednisolone; Pulse Therapy, Drug; Stevens-Johnson Syndrome

2016
Acute fibrinous and organising pneumonia.
    BMJ case reports, 2017, Sep-07, Volume: 2017

    Topics: Anti-Bacterial Agents; Biopsy; Community-Acquired Infections; Cryptogenic Organizing Pneumonia; Diagnosis, Differential; Female; Fever; Fibrin; Glucocorticoids; Humans; Legionella pneumophila; Legionnaires' Disease; Levofloxacin; Lung; Lung Diseases, Interstitial; Middle Aged; Pneumonia; Prednisolone; Radiography; Rare Diseases; Tomography, X-Ray Computed; Treatment Outcome

2017
Blurry Vision and Eye Pain After Pterygium Surgery.
    JAMA ophthalmology, 2018, 07-01, Volume: 136, Issue:7

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Eye Infections, Bacterial; Eye Pain; Female; Glucocorticoids; Humans; Indomethacin; Intraocular Pressure; Levofloxacin; Moxifloxacin; Ophthalmologic Surgical Procedures; Prednisolone; Pseudomonas aeruginosa; Pseudomonas Infections; Pterygium; Scleritis; Vision Disorders; Visual Acuity

2018
[Chorioretinis sclopetaria].
    Journal francais d'ophtalmologie, 2018, Volume: 41, Issue:5

    Topics: Adult; Chorioretinitis; Eye Injuries, Penetrating; Firearms; Foreign Bodies; Humans; Levofloxacin; Male; Nasal Cavity; Orbit; Orthognathic Surgical Procedures; Plastic Surgery Procedures; Prednisolone; Tomography, Optical Coherence; Tomography, X-Ray Computed; Wounds, Gunshot

2018
Topical levofloxacin, nepafenac and prednisolone acetate medication after cataract surgery in the biggest tertiary eye hospital in Finland during 2015-2018.
    Acta ophthalmologica, 2019, Volume: 97, Issue:6

    Topics: Administration, Topical; Anti-Bacterial Agents; Anti-Inflammatory Agents; Benzeneacetamides; Cataract Extraction; Drug Therapy, Combination; Female; Finland; Follow-Up Studies; Humans; Incidence; Levofloxacin; Male; Ophthalmic Solutions; Phenylacetates; Postoperative Care; Prednisolone; Retrospective Studies; Surgical Wound Infection; Treatment Outcome; Visual Acuity

2019
Methods for achieving low endophthalmitis rates in phacoemulsification cataract surgery.
    Acta ophthalmologica, 2020, Volume: 98, Issue:1

    Topics: Benzeneacetamides; Cataract; Endophthalmitis; Finland; Humans; Levofloxacin; Phacoemulsification; Phenylacetates; Prednisolone

2020
The clinical value of two combination regimens in the Management of Patients Suffering from Covid-19 pneumonia: a single centered, retrospective, observational study.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2020, Volume: 28, Issue:2

    Topics: Adult; Aged; Azithromycin; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Drug Therapy, Combination; Female; Hospitalization; Humans; Hydroxychloroquine; Iran; Length of Stay; Levofloxacin; Lopinavir; Male; Meropenem; Middle Aged; Naproxen; Oseltamivir; Pneumonia, Viral; Prednisolone; Retrospective Studies; Ritonavir; Treatment Outcome; Vancomycin

2020
Development of a dual delivery of levofloxacin and prednisolone acetate via PLGA nanoparticles/ thermosensitive chitosan-based hydrogel for postoperative management: An in-vitro and ex-vivo study.
    International journal of biological macromolecules, 2021, Jun-01, Volume: 180

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cell Survival; Cells, Cultured; Chitosan; Cytokines; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug Therapy, Combination; Endophthalmitis; Epithelial Cells; Epithelium, Corneal; Hydrogels; Keratitis; Levofloxacin; Nanoparticles; Particle Size; Postoperative Complications; Prednisolone; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Temperature

2021