Page last updated: 2024-09-04

levofloxacin and posaconazole

levofloxacin has been researched along with posaconazole in 4 studies

Compound Research Comparison

Studies
(levofloxacin)
Trials
(levofloxacin)
Recent Studies (post-2010)
(levofloxacin)
Studies
(posaconazole)
Trials
(posaconazole)
Recent Studies (post-2010) (posaconazole)
4,3465812,2091,5751031,014

Protein Interaction Comparison

ProteinTaxonomylevofloxacin (IC50)posaconazole (IC50)
Bile salt export pumpHomo sapiens (human)8.1
Steroid 17-alpha-hydroxylase/17,20 lyaseHomo sapiens (human)0.921
Cytochrome P450 3A4Homo sapiens (human)0.2458
AromataseHomo sapiens (human)8.4
Cytochrome P450 2C9 Homo sapiens (human)7.2
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.31
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.021
Sterol 14-alpha demethylaseTrypanosoma cruzi strain CL Brener0.464
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Frauenfelder, T; Gerber, B; Köppel, J; Manz, MG; Nair, G; Nguyen-Kim, TD; Paul, M; Schanz, U1
Bateman, AC; Clarridge, J; Garvin, K; Greenbaum, A; Grim, J; Liu, AW1

Reviews

1 review(s) available for levofloxacin and posaconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for levofloxacin and posaconazole

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Efficacy of anti-fungal but not anti-bacterial prophylaxis in intensive primary AML therapy: a real-world, retrospective comparative single-centre study.
    Swiss medical weekly, 2014, Volume: 144

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Antifungal Agents; Antineoplastic Agents; Bacteremia; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Levofloxacin; Male; Middle Aged; Mycoses; Retrospective Studies; Survival Rate; Triazoles

2014
Cutaneous phaeohyphomycosis in a hematopoietic stem cell transplant patient caused by Alternaria rosae: First case report.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:3

    Topics: Acute Kidney Injury; Acyclovir; Aged; Alternaria; Alternariosis; Antibiotic Prophylaxis; Antifungal Agents; Drug Therapy, Combination; Fatal Outcome; Graft vs Host Disease; Hand; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Levofloxacin; Magnetic Resonance Imaging; Male; Microbial Sensitivity Tests; Paranasal Sinuses; Phaeohyphomycosis; Pneumonia; Prednisone; Primary Myelofibrosis; Respiratory Insufficiency; Spores, Fungal; Transplantation, Homologous; Triazoles; Voriconazole

2017