Page last updated: 2024-09-04

levofloxacin and pemetrexed

levofloxacin has been researched along with pemetrexed in 2 studies

Compound Research Comparison

Studies
(levofloxacin)
Trials
(levofloxacin)
Recent Studies (post-2010)
(levofloxacin)
Studies
(pemetrexed)
Trials
(pemetrexed)
Recent Studies (post-2010) (pemetrexed)
4,3465812,2092,4696571,695

Protein Interaction Comparison

ProteinTaxonomylevofloxacin (IC50)pemetrexed (IC50)
Thymidylate synthase Escherichia coli1.1
Dihydrofolate reductaseHomo sapiens (human)4.0309
Dihydrofolate reductaseLacticaseibacillus casei2.3
Thymidylate synthaseHomo sapiens (human)8.1787
Dihydrofolate reductaseEscherichia coli K-122.3
Folate receptor betaHomo sapiens (human)0.2585
Folate receptor alphaHomo sapiens (human)0.2417
Trifunctional purine biosynthetic protein adenosine-3Homo sapiens (human)0.0342
Bifunctional purine biosynthesis protein ATICHomo sapiens (human)0.07
Reduced folate transporterHomo sapiens (human)0.0928
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii1.655
Proton-coupled folate transporterHomo sapiens (human)0.0229

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Matsuyama, K1

Reviews

2 review(s) available for levofloxacin and pemetrexed

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Development of a Prodrug of Levofloxacin to Avoid Chelation with Al
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2017, Volume: 137, Issue:9

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Chelating Agents; Drug Discovery; Esters; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Hydrolysis; Levofloxacin; Nucleic Acid Synthesis Inhibitors; Pemetrexed; Prodrugs; Rats

2017