Page last updated: 2024-09-04

levofloxacin and miconazole

levofloxacin has been researched along with miconazole in 9 studies

Compound Research Comparison

Studies
(levofloxacin)
Trials
(levofloxacin)
Recent Studies (post-2010)
(levofloxacin)
Studies
(miconazole)
Trials
(miconazole)
Recent Studies (post-2010) (miconazole)
4,3465812,2092,309238476

Protein Interaction Comparison

ProteinTaxonomylevofloxacin (IC50)miconazole (IC50)
Metabotropic glutamate receptor 6Homo sapiens (human)6.5
AcetylcholinesteraseElectrophorus electricus (electric eel)2.4
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)5.314
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Mus musculus (house mouse)4.55
Cytochrome P450 1A2 Rattus norvegicus (Norway rat)4.55
Cytochrome P450 1A2Homo sapiens (human)4.55
Tyrosine-protein kinase FynHomo sapiens (human)4.16
Heme oxygenase 1 Rattus norvegicus (Norway rat)5.8
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.939
Muscarinic acetylcholine receptor M2Homo sapiens (human)4.336
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.197
ATP-dependent translocase ABCB1Homo sapiens (human)3
Cytochrome P450 3A4Homo sapiens (human)0.4938
Alpha-2A adrenergic receptorHomo sapiens (human)3.966
Adenosine receptor A3Homo sapiens (human)2.811
Cytochrome P450 2D6Homo sapiens (human)1.32
Muscarinic acetylcholine receptor M1Homo sapiens (human)3.971
AromataseHomo sapiens (human)0.6
Cytochrome P450 2C9 Homo sapiens (human)0.2
Beta-3 adrenergic receptorHomo sapiens (human)5.482
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)3.7
Androgen receptorRattus norvegicus (Norway rat)7.089
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)2.811
Alpha-2B adrenergic receptorHomo sapiens (human)3.598
Muscarinic acetylcholine receptor M3Homo sapiens (human)3.154
ATP-dependent translocase ABCB1Mus musculus (house mouse)7.8
Substance-K receptorHomo sapiens (human)4.839
D(1A) dopamine receptorHomo sapiens (human)6.247
Heme oxygenase 2Rattus norvegicus (Norway rat)5.8
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.939
Thromboxane-A synthase Homo sapiens (human)0.263
Histamine H2 receptorHomo sapiens (human)6.75
Alpha-1D adrenergic receptorHomo sapiens (human)3.046
Substance-P receptorHomo sapiens (human)6.813
5-hydroxytryptamine receptor 2AHomo sapiens (human)3.907
5-hydroxytryptamine receptor 2CHomo sapiens (human)5.314
Sodium-dependent serotonin transporterHomo sapiens (human)0.778
Cytochrome P450 2C19Homo sapiens (human)0.008
Mu-type opioid receptorHomo sapiens (human)6.059
D(3) dopamine receptorHomo sapiens (human)3.199
Delta-type opioid receptorHomo sapiens (human)3.387
Kappa-type opioid receptorHomo sapiens (human)6.594
5-hydroxytryptamine receptor 2BHomo sapiens (human)5.545
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)2.811
CholinesteraseEquus caballus (horse)5.55
Sodium-dependent dopamine transporter Homo sapiens (human)1.701
Lanosterol 14-alpha demethylaseHomo sapiens (human)0.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)6.7

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Al-Taweel, SA; Al-Trawneh, SA; Cavazzoni, A; El-Abadelah, MM; Incerti, M; Vicini, P; Zahra, JA; Zani, F1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bahekar, SS; Jawale, CS; Karnik, KS; Pansare, DN; Pawar, CD; Sarkate, AP; Shelke, RN; Shinde, DB1
Zhang, B1
Gao, F; Huang, G; Xiao, J1

Reviews

2 review(s) available for levofloxacin and miconazole

ArticleYear
Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids.
    European journal of medicinal chemistry, 2019, Apr-15, Volume: 168

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles

2019
Current scenario of tetrazole hybrids for antibacterial activity.
    European journal of medicinal chemistry, 2019, Dec-15, Volume: 184

    Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles

2019

Other Studies

7 other study(ies) available for levofloxacin and miconazole

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Thienopyridines; Topoisomerase II Inhibitors

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Synthesis and antimicrobial evaluation of novel ethyl 2-(2-(4-substituted)acetamido)-4-subtituted-thiazole-5-carboxylate derivatives.
    Bioorganic & medicinal chemistry letters, 2016, 08-01, Volume: 26, Issue:15

    Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus flavus; Aspergillus niger; Bacillus subtilis; Candida albicans; Carboxylic Acids; Dose-Response Relationship, Drug; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship; Thiazoles

2016