levofloxacin has been researched along with metyrapone in 4 studies
| Studies (levofloxacin) | Trials (levofloxacin) | Recent Studies (post-2010) (levofloxacin) | Studies (metyrapone) | Trials (metyrapone) | Recent Studies (post-2010) (metyrapone) |
|---|---|---|---|---|---|
| 4,346 | 581 | 2,209 | 3,415 | 128 | 250 |
| Protein | Taxonomy | levofloxacin (IC50) | metyrapone (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 4.8 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2.8659 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 5 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 4.6 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 7.83 | |
| Cytochrome P450 11B1, mitochondrial | Rattus norvegicus (Norway rat) | 4.7357 | |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | 0.0181 | |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | 0.0838 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for levofloxacin and metyrapone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 other study(ies) available for levofloxacin and metyrapone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |