levofloxacin has been researched along with loperamide in 9 studies
| Studies (levofloxacin) | Trials (levofloxacin) | Recent Studies (post-2010) (levofloxacin) | Studies (loperamide) | Trials (loperamide) | Recent Studies (post-2010) (loperamide) |
|---|---|---|---|---|---|
| 4,346 | 581 | 2,209 | 1,358 | 196 | 488 |
| Protein | Taxonomy | levofloxacin (IC50) | loperamide (IC50) |
|---|---|---|---|
| Cocaine esterase | Homo sapiens (human) | 5.7 | |
| Beta-2 adrenergic receptor | Homo sapiens (human) | 3.005 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 2.5 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 9.27 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Histamine H2 receptor | Homo sapiens (human) | 3.081 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 2.202 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0014 | |
| D(3) dopamine receptor | Homo sapiens (human) | 1.337 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.896 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 3.125 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 4.105 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.033 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 0.239 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.628 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dai, JG; Ge, GB; Hu, YC; Li, R; Lin, PC; Lin, S; Qiu, BL; Sun, ZH; Wang, LY; Wu, YZ; Xia, GY; Zhang, HW; Zhang, JF | 1 |
| Frenck, RW; Johnston, JR; Monteville, MR; Putnam, SD; Riddle, MS; Rockabrand, DM; Sanders, JW; Tribble, DR; Ulukan, S | 1 |
| Connor, P; Danboise, B; Fraser, J; Gutierrez, RL; Hulseberg, C; Hutley, EJ; Lalani, T; Porter, CK; Riddle, MS; Simons, MP; Swierczewski, B; Tribble, DR | 1 |
2 review(s) available for levofloxacin and loperamide
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for levofloxacin and loperamide
| Article | Year |
|---|---|
Azithromycin and loperamide are comparable to levofloxacin and loperamide for the treatment of traveler's diarrhea in United States military personnel in Turkey.
Topics: Adult; Azithromycin; Campylobacter Infections; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Escherichia coli Infections; Feces; Female; Humans; Levofloxacin; Loperamide; Male; Military Personnel; Nausea; Ofloxacin; Salmonella Infections; Time Factors; Travel; Turkey; United States | 2007 |
Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide.
Topics: Acute Disease; Adult; Afghanistan; Anti-Bacterial Agents; Azithromycin; Diarrhea; Djibouti; Double-Blind Method; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Female; Honduras; Humans; Kenya; Levofloxacin; Loperamide; Male; Military Personnel; Travel; Treatment Outcome | 2017 |
5 other study(ies) available for levofloxacin and loperamide
| Article | Year |
|---|---|
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Bysspectin A, an unusual octaketide dimer and the precursor derivatives from the endophytic fungus Byssochlamys spectabilis IMM0002 and their biological activities.
Topics: Anti-Bacterial Agents; Biocatalysis; Byssochlamys; Carboxylesterase; Carboxylic Ester Hydrolases; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Polyketides; Staphylococcus aureus; Structure-Activity Relationship | 2018 |