Page last updated: 2024-09-04

levofloxacin and lomefloxacin

levofloxacin has been researched along with lomefloxacin in 38 studies

Compound Research Comparison

Studies
(levofloxacin)
Trials
(levofloxacin)
Recent Studies (post-2010)
(levofloxacin)
Studies
(lomefloxacin)
Trials
(lomefloxacin)
Recent Studies (post-2010) (lomefloxacin)
4,3465812,20962083134

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (10.53)18.2507
2000's27 (71.05)29.6817
2010's7 (18.42)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baroni, M; Cecchetti, V; Cianchetta, G; Cruciani, G; Mannhold, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Arakawa, Y; Kato, H; Kimura, K; Konda, T; Shibata, N; Shibayama, K; Suzuki, S; Wachino, J; Yamane, K1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Azéma, J; Dewelle, J; Guidetti, B; Kiss, R; Korolyov, A; Le Calve, B; Malet-Martino, M; Martino, R; Mijatovic, T; Vaysse, J1
Gozalbes, R; Pineda-Lucena, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Blaskovich, MAT; Pham, TDM; Ziora, ZM1
Ballesta, S; García, I; Pascual, A; Perea, EJ1
Hoogkamp-Korstanje, JA1
Callery-D'Amico, S; Cox, CE; Fowler, CL; Kim, SS; King, W; Klimberg, IW1
Anjo, S; Hara, A; Nakamura, M; Sakai, M1
Greenberg, RN; Newman, MT; Pectol, RW; Shariaty, S1
Baumann-Wilschke, I; Rücker, M; Shakibaei, M; Stahlmann, R1
Schaeffer, AJ1
Furuhama, K; Itoh, S; Katoh, M1
Chiang, SR; Chuang, YC; Ko, WC; Lee, HC; Tang, HJ; Wang, YY1
Ono, C; Tanaka, M1
Kawai, M; Mashima, Y; Mochizuki, H; Yamada, K; Yamada, M1
Maĭchuk, IuF1
Hong, JW; Hu, CQ; Sheng, LS1
Li, JL; Ma, XC; Tu, ZH; Xin, J; Zhang, T1
Naber, KG1
Hasegawa, M; Kobayashi, I; Koyama, H; Matsuzaki, K; Sato, Y; Watabe, E1
Artemenko, N; Gorelov, A; Perekalina, T; Smelov, V; Smelova, N; Ukleeva, G1
Kassab, NM; Kedor-Hackmam, ER; Santoro, MI; Singh, AK1
Ishikawa, K; Kawai, M; Mochizuki, H; Yamada, M1
Bayar, B; Bozkurt, A; Dinçel, A; Duman, S; Kaya, E; Oflu, Y; Yağci, R; Yağci, S1
Ni, YN; Zhang, GW1
Andreeva, I; Rafalsky, V; Rjabkova, E1
Fukumori, S; Hashimoto, Y; Murata, T; Taguchi, M; Tahara, K; Takaai, M1
Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M1
Carda-Broch, S; Esteve-Romero, J; Rambla-Alegre, M1
Anisimov, BI; Ryzhko, IV; Trishina, AV; Tsuraeva, RI1
Alves, G; Falcão, A; Fortuna, A; Lino, C; Pena, A; Sousa, J1
Jia, XQ; Li, YH; Pang, F; Wang, B; Zhao, QG1
Betlejewska-Kielak, K; Biernacka, J; Grudzień, M; Kłosińska-Szmurło, E; Mazurek, AP; Pluciński, F1

Reviews

5 review(s) available for levofloxacin and lomefloxacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Quinolone antibiotics.
    MedChemComm, 2019, Oct-01, Volume: 10, Issue:10

    Topics:

2019
The expanding role of fluoroquinolones.
    The American journal of medicine, 2002, Jul-08, Volume: 113 Suppl 1A

    Topics: Anti-Infective Agents; Anti-Infective Agents, Urinary; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Urinary Tract Infections

2002
Levofloxacin in the treatment of urinary tract infections and prostatitis.
    Journal of chemotherapy (Florence, Italy), 2004, Volume: 16 Suppl 2

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Female; Fluoroquinolones; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Prostatitis; Quinolones; Severity of Illness Index; Treatment Outcome; Urinary Tract Infections

2004
Quinolones for uncomplicated acute cystitis in women.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Acute Disease; Adult; Anti-Infective Agents, Urinary; Ciprofloxacin; Cystitis; Female; Fluoroquinolones; Humans; Levofloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Quinolones; Randomized Controlled Trials as Topic

2006

Trials

2 trial(s) available for levofloxacin and lomefloxacin

ArticleYear
A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection.
    Urology, 1998, Volume: 51, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Quinolones; Urinary Tract Infections

1998
Ciprofloxacin, lomefloxacin, or levofloxacin as treatment for chronic osteomyelitis.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:1

    Topics: Adult; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Fluoroquinolones; Follow-Up Studies; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Osteomyelitis; Quinolones

2000

Other Studies

31 other study(ies) available for levofloxacin and lomefloxacin

ArticleYear
Chemometric studies on the bactericidal activity of quinolones via an extended VolSurf approach.
    Journal of medicinal chemistry, 2004, Jun-03, Volume: 47, Issue:12

    Topics: Anti-Bacterial Agents; Enterococcus faecalis; Escherichia coli; Models, Molecular; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Quinolones; Staphylococcus aureus; Thermodynamics

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chitosan; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Humans; Malates; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Transformation, Bacterial; Uncoupling Agents

2007
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
    Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum Tolerated Dose; Mice; Neoplasms; Piperazine; Piperazines

2009
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Uptake of 5 fluoroquinolones into human polymorphonuclear cells].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14, Issue:8

    Topics: Anti-Infective Agents; Biological Transport; Fleroxacin; Fluorometry; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Levofloxacin; Neutrophils; Norfloxacin; Ofloxacin; Quinolones; Temperature

1996
In-vitro activities of ciprofloxacin, levofloxacin, lomefloxacin, ofloxacin, pefloxacin, sparfloxacin and trovafloxacin against gram-positive and gram-negative pathogens from respiratory tract infections.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:3

    Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Pefloxacin; Quinolones; Respiratory Tract Infections

1997
Comparison of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy.
    Journal of pharmaceutical and biomedical analysis, 1999, Volume: 18, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Levofloxacin; Magnetic Resonance Spectroscopy; Metals; Ofloxacin; Quinolones; Solutions; Temperature

1999
Ultrastructural characterization of murine limb buds after in vitro exposure to grepafloxacin and other fluoroquinolones.
    Archives of toxicology, 2002, Volume: 75, Issue:11-12

    Topics: Abnormalities, Drug-Induced; Animals; Anti-Infective Agents; Calcium; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fluoroquinolones; In Vitro Techniques; Levofloxacin; Limb Buds; Magnesium; Male; Mice; Mice, Inbred Strains; Ofloxacin; Piperazines; Pregnancy; Quinolones

2002
In vivo photochemical micronucleus induction due to certain quinolone antimicrobial agents in the skin of hairless mice.
    Mutation research, 2002, Sep-26, Volume: 520, Issue:1-2

    Topics: Animals; Anti-Infective Agents; Chromosome Aberrations; Dose-Response Relationship, Drug; Fluoroquinolones; Levofloxacin; Light; Male; Mice; Mice, Hairless; Micronuclei, Chromosome-Defective; Micronucleus Tests; Ofloxacin; Photosensitizing Agents; Quinolones; Skin; Time Factors

2002
In vitro and in vivo activities of fluoroquinolones against Aeromonas hydrophila.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7

    Topics: Aeromonas hydrophila; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Cefotaxime; Ciprofloxacin; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Levofloxacin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Moxifloxacin; Ofloxacin; Quinolines; Quinolones

2003
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:8

    Topics: Binding Sites; Chloroquine; Ciprofloxacin; Drug Interactions; Enoxacin; Fluoroquinolones; Levodopa; Levofloxacin; Melanins; Monophenol Monooxygenase; Norfloxacin; Ofloxacin; Quinolones; Timolol

2003
Aqueous humor levels of topically applied levofloxacin, norfloxacin, and lomefloxacin in the same human eyes.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:9

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Urinary; Aqueous Humor; Chromatography, High Pressure Liquid; Female; Fluoroquinolones; Humans; Levofloxacin; Male; Norfloxacin; Ofloxacin; Quinolones

2003
[Levofloxacin (Tavanic) in the treatment of corneal ulcers].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2003, Volume: 48, Issue:6

    Topics: Administration, Oral; Anti-Infective Agents; Corneal Ulcer; Drug Administration Schedule; Drug Therapy, Combination; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Ofloxacin; Ophthalmic Solutions; Quinolones; Treatment Outcome

2003
[Analysis of the response factors of different quinolones detected by evaporative light-scattering detector].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:9

    Topics: Chromatography, High Pressure Liquid; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Light; Linear Models; Ofloxacin; Quinolones

2003
Compare two methods of measuring DNA damage induced by photogenotoxicity of fluoroquinolones.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:2

    Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Comet Assay; Cricetinae; Cricetulus; DNA; DNA Damage; Fibroblasts; Fluoroquinolones; Levofloxacin; Ofloxacin; Quinolones; Ultraviolet Rays

2004
[Antimicrobial susceptibility surveillance of recent isolates from ophthalmological infections to gatifloxacin and other antimicrobial drugs].
    The Japanese journal of antibiotics, 2005, Volume: 58, Issue:1

    Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; Levofloxacin; Ofloxacin; Quinolones

2005
Chlamydia trachomatis survival in the presence of two fluoroquinolones (lomefloxacin versus levofloxacin) in patients with chronic prostatitis syndrome.
    Andrologia, 2005, Volume: 37, Issue:2-3

    Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Chronic Disease; Fluoroquinolones; Humans; Levofloxacin; Male; Ofloxacin; Prostatitis; Quinolones

2005
Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 2006, Jan-23, Volume: 40, Issue:1

    Topics: Anti-Bacterial Agents; Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Ethylamines; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Levofloxacin; Models, Chemical; Models, Statistical; Ofloxacin; Pefloxacin; Pharmaceutical Preparations; Quinolones; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Temperature; Time Factors

2006
Corneal penetration of simultaneously applied topical levofloxacin, norfloxacin and lomefloxacin in human eyes.
    Acta ophthalmologica Scandinavica, 2006, Volume: 84, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cornea; Female; Fluoroquinolones; Humans; Keratoplasty, Penetrating; Levofloxacin; Male; Middle Aged; Norfloxacin; Ofloxacin; Quinolones; Tissue Distribution

2006
Penetration of second-, third-, and fourth-generation topical fluoroquinolone into aqueous and vitreous humour in a rabbit endophthalmitis model.
    Eye (London, England), 2007, Volume: 21, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Aqueous Humor; Aza Compounds; Ciprofloxacin; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Levofloxacin; Moxifloxacin; Ofloxacin; Ophthalmic Solutions; Quinolines; Rabbits; Staphylococcal Infections; Vitreous Body

2007
[Synchronous fluorimetric determination of the residues of three quinolones in Eel by partial least squares].
    Guang pu xue yu guang pu fen xi = Guang pu, 2006, Volume: 26, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Drug Residues; Eels; Fluorometry; Fluoroquinolones; Least-Squares Analysis; Levofloxacin; Norfloxacin; Ofloxacin; Quinolones; Seafood

2006
The apical uptake transporter of levofloxacin is distinct from the peptide transporter in human intestinal epithelial Caco-2 cells.
    Drug metabolism and pharmacokinetics, 2008, Volume: 23, Issue:5

    Topics: Biological Transport; Caco-2 Cells; Cell Compartmentation; Dipeptides; Fluoroquinolones; Humans; Intestinal Absorption; Levofloxacin; Membrane Transport Proteins; Ofloxacin; Peptide Transporter 1; Symporters

2008
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
    Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Diclofenac; Dioxolanes; Drug Combinations; Drug Interactions; Enoxacin; Fleroxacin; Fluoroquinolones; Gatifloxacin; Levofloxacin; Male; Mice; Microbial Sensitivity Tests; Naphthyridines; Norfloxacin; Ofloxacin; Oxazines; Phenylacetates; Piperazines; Receptors, GABA-A; Seizures

2009
Validation of a MLC method with fluorescence detection for the determination of quinolones in urine samples by direct injection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Dec-01, Volume: 877, Issue:31

    Topics: Anti-Bacterial Agents; Aza Compounds; Calibration; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluorescence; Fluoroquinolones; Humans; Levofloxacin; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Reproducibility of Results

2009
[Efficacy of levofloxacin, lomefloxacin and moxifloxacin vs. other fluoroquinolones in experimental plague due to FI+ and FI- strains of Yersinia pestis in Albino mice].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2009, Volume: 54, Issue:5-6

    Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoroquinolones; Humans; Levofloxacin; Mice; Moxifloxacin; Ofloxacin; Plague; Quinolines; Species Specificity; Time Factors; Yersinia pestis

2009
Development and validation of a fast isocratic liquid chromatography method for the simultaneous determination of norfloxacin, lomefloxacin and ciprofloxacin in human plasma.
    Biomedical chromatography : BMC, 2011, Volume: 25, Issue:5

    Topics: Anti-Infective Agents; Chromatography, Liquid; Ciprofloxacin; Drug Stability; Fluoroquinolones; Humans; Levofloxacin; Linear Models; Norfloxacin; Ofloxacin; Reproducibility of Results; Sensitivity and Specificity

2011
Control of an outbreak due to orthopedic infections caused by Enterobacteriaceae producing IMP-4 or IMP-8 carbapenemases.
    Pathologie-biologie, 2014, Volume: 62, Issue:3

    Topics: Adolescent; Anti-Bacterial Agents; Arthritis, Infectious; beta-Lactam Resistance; beta-Lactamases; China; Cross Infection; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Fluoroquinolones; Fracture Fixation, Internal; Humans; Infection Control; Klebsiella Infections; Klebsiella oxytoca; Levofloxacin; Male; Meropenem; Middle Aged; Osteitis; Patient Isolation; Protective Clothing; Retrospective Studies; Surgical Wound Infection; Thienamycins; Universal Precautions; Wound Infection

2014
Physicochemical properties of lomefloxacin, levofloxacin, and moxifloxacin relevant to the biopharmaceutics classification system.
    Acta chimica Slovenica, 2014, Volume: 61, Issue:4

    Topics: Anti-Bacterial Agents; Biopharmaceutics; Chemistry, Pharmaceutical; Electrochemistry; Fluoroquinolones; Gastrointestinal Tract; Humans; Hydrogen-Ion Concentration; Levofloxacin; Models, Molecular; Molecular Conformation; Moxifloxacin; Permeability; Phosphates; Potentiometry; Protons; Quantum Theory; Solubility; Solvents; Static Electricity; Temperature

2014