levofloxacin has been researched along with imipenem, anhydrous in 116 studies
| Studies (levofloxacin) | Trials (levofloxacin) | Recent Studies (post-2010) (levofloxacin) | Studies (imipenem, anhydrous) | Trials (imipenem, anhydrous) | Recent Studies (post-2010) (imipenem, anhydrous) |
|---|---|---|---|---|---|
| 4,346 | 581 | 2,209 | 4,784 | 391 | 1,397 |
| Protein | Taxonomy | levofloxacin (IC50) | imipenem, anhydrous (IC50) |
|---|---|---|---|
| Beta-lactamase | Pseudomonas aeruginosa | 0.15 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (4.31) | 18.2507 |
| 2000's | 54 (46.55) | 29.6817 |
| 2010's | 43 (37.07) | 24.3611 |
| 2020's | 14 (12.07) | 2.80 |
| Authors | Studies |
|---|---|
| Appelbaum, PC; Credito, KL; DeWasse, B; Kosowska-Shick, K; McGhee, P; Pankuch, GA | 1 |
| Barth, AL; Castanheira, M; Gales, AC; Nicoletti, AG; Pereira, AS; Pignatari, AC | 1 |
| Bradbury, BJ; Buechter, DD; Cheng, J; Deshpande, M; Mushtaq, G; Podos, SD; Pucci, MJ; Thanassi, JA; Thoma, CL; Vigliotti, GA | 1 |
| Cauda, R; Citton, R; D'Inzeo, T; Fadda, G; Fiori, B; Montuori, E; Posteraro, B; Sanguinetti, M; Spanu, T; Trecarichi, EM; Tumbarello, M | 1 |
| Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Luzzaro, F; Mantengoli, E; Migliavacca, R; Pagani, L; Rossolini, GM; Toniolo, A | 1 |
| Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR | 1 |
| Hovde, LB; Kroeger, LA; Mitropoulos, IF; Rotschafer, JC; Schafer, J | 1 |
| Henrichfreise, B; Luhmer-Becker, I; Wiedemann, B; Wiegand, I | 1 |
| Chen, M; Guo, P; Sun, H; Wang, H; Xu, Y; Yang, Q; Zhu, Y | 1 |
| Appelbaum, PC; Clark, CL; Ednie, LM; Kosowska-Shick, K | 1 |
| Calvet, L; Devine, R; Dubreuil, L; Jean-Pierre, H; Jumas-Bilak, E; Marchandin, H; Mercier, G; Morio, F | 1 |
| Iredell, JR; Partridge, SR; Zong, Z | 1 |
| Brémont, S; Courvalin, P; Damier-Piolle, L; Lambert, T; Magnet, S | 1 |
| Fritsche, TR; Jones, RN; Sader, HS | 1 |
| Arakawa, Y; Suzuki, S; Wachino, J; Yamane, K | 1 |
| Bethel, CR; Bonomo, RA; Carias, LL; Endimiani, A; Fox, WR; Hall, GS; Hujer, AM; Hujer, KM; Hutton, RA; Jacobs, MR; Jenkins, SG; Paterson, DL; Perez, F; Rice, LB; Tenover, FC | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Carmeli, Y; Chmelnitsky, I; Navon-Venezia, S; Strahilevitz, J | 1 |
| Craft, DW; Hachmeister, L; Hong, SG; Kim, SY; Moland, ES; Sayed, SD; Thomson, KS | 1 |
| Fukuoka, T; Kakuta, M; Koga, T; Masuda, N; Namba, E; Sugihara, C | 2 |
| Cauda, R; D'Inzeo, T; De Pascale, G; Fadda, G; Fiori, B; Leone, F; Rossi, M; Sali, M; Sanguinetti, M; Spanu, T; Trecarichi, EM; Tumbarello, M | 1 |
| Bratu, S; Georgescu, C; Landman, D; Martin, DA; Quale, J | 1 |
| Biek, D; Ge, Y; Sahm, DF; Talbot, GH | 1 |
| Hsueh, PR; Huang, YT; Liao, CH; Lin, HY; Liu, CY; Yen, LC | 1 |
| Cattoir, V; Nordmann, P; Poirel, L | 1 |
| Amicosante, G; De Luca, F; Luzzaro, F; Migliavacca, R; Mugnaioli, C; Pagani, L; Perilli, M; Pini, B; Pollini, S; Rossolini, GM; Spalla, M; Toniolo, A | 1 |
| Bennett, JW; Herrera, ML; Jorgensen, JH; Lewis, JS; Wickes, BW | 1 |
| Bradford, PA; Jones, CH; Mansour, TS; Petersen, PJ; Projan, SJ; Venkatesan, AM | 1 |
| Baptista, BC; Correia, JD; da Fonseca, JD; Martínez-Martínez, L; Pomba, C | 1 |
| Bradford, PA; Jones, CH; Keeney, D; Ruzin, A; Tuckman, M | 1 |
| Brown, SD; Traczewski, MM | 1 |
| Cui, L; Hiramatsu, K; Neoh, HM; Shoji, M | 1 |
| Appelbaum, PC; Ednie, LM; Kosowska-Shick, K; McGhee, P | 1 |
| Badal, RE; Bouchillon, SK; Hawser, SP; Hoban, DJ; Hsueh, PR; Paterson, DL | 1 |
| Brunner, LS; Haas, W; Lee, JC; Morris, TW; Pillar, CM; Zurenko, GE | 1 |
| Distèche-Nguyen, M; Gerards, T; Luxen, A; Miguet, L; Pasha, FA; Thomas, A; Zervosen, A | 1 |
| Albertí, S; Bengoechea, JA; Doménech-Sánchez, A; Llobet, E; Martínez-Martínez, L; Padilla, E | 1 |
| Bulik, CC; Christensen, H; Nicolau, DP | 1 |
| Dunman, PM; Hood, MI; Jacobs, AC; Sayood, K; Skaar, EP | 1 |
| Aquino, EE; León, CF; Otero, DM; Robledo, IE; Santana, JL; Santé, MI; Vázquez, GJ | 1 |
| Hakanen, AJ; Huovinen, P; Kotilainen, P; Lehtopolku, M; Nakari, UM; Siitonen, A | 1 |
| Chen, HC; King, CH; Lai, JF; Lauderdale, TL; Shiau, YR | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Chang, SC; Chen, YC; Hsia, KC; Li, SY; Liao, MH; Lin, YC; Sheng, WH | 1 |
| Flamm, R; Friedland, I; Kaniga, K; Lee, M; Redman, R; Tong, SY | 1 |
| Carmeli, Y; Chmelnitsky, I; Goren, MG; Navon-Venezia, S | 1 |
| Bajaksouzian, S; Biek, D; Critchley, IA; Good, CE; Jacobs, MR; Jones, RN; Sader, HS; Windau, AR | 1 |
| Carmeli, Y; Chmelnitsky, I; Goren, MG; Leavitt, A; Navon-Venezia, S; Ofek, I | 1 |
| Barber, M; Eberly, LE; Feeney, LA; Miller, GH; Summers, A; Wortmann, G; Zapor, MJ | 1 |
| Badal, RE; Baquero, F; Bouchillon, SK; Cantón, R; Hawser, SP; Hoban, DJ | 1 |
| Badal, RE; Bouchillon, SK; DiPersio, J; Hawser, SP; Hoban, DJ; Labombardi, VJ | 1 |
| Bai, N; Cai, Y; Li, R; Liang, B; Liu, Y; Wang, R | 1 |
| Bavari, S; Bowlin, TL; Butler, MM; Moir, DT; Panchal, RG; Peet, NP; Shinabarger, DL; Williams, JD | 1 |
| Clark, M; Doolittle, J; Giddings, MC; Khatun, J; Ramkissoon, K; Secrest, A; Su, HC; Wolfgang, MC | 1 |
| Chan, MC; Chang, TY; Chiueh, TS; Sun, JR; Wang, WY | 1 |
| Hamprecht, A; Higgins, PG; Schneiders, T; Seifert, H | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bera, S; Mondal, D | 1 |
| Gao, F; Huang, G; Xiao, J | 1 |
| Flynn, CM; Johnson, DM; Jones, RN | 1 |
| Aikawa, N; Denno, R; Fujimoto, M; Hirata, AK; Ishibiki, K; Ishihara, R; Ishikawa, S; Iwai, S; Kinoshita, H; Koide, H; Kunimatsu, M; Manabe, T; Mashita, K; Mizuno, A; Morimoto, K; Mukaiya, M; Ohnishi, H; Ohtsuka, K; Sakaguchi, S; Shinagawa, N; Takuma, K; Tanimura, H; Umemoto, Y; Ushijima, Y; Yura, J | 1 |
| Takazakura, E; Tsuji, H | 1 |
| Hikida, M; Igarashi, A; Itahashi, K; Kitamura, M; Shiba, T | 1 |
| Geddes, A; Härkönen, M; Jacobs, F; Nowotny, I; Schonwald, S; Thaler, M | 1 |
| Bryskier, A; Carbon, C; Farinotti, R; Joly-Guillou, ML; Wolff, M | 1 |
| Hashido, H; Ishigo, S; Iwata, I; Matsubara, S; Matsukawa, Y; Mikamo, H; Sawamura, H; Suematsu, H; Tamaya, T | 1 |
| Harada, H; Iwasaki, Y; Minagawa, T; Nagata, K; Nakagawa, M; Nakanishi, M; Natsuhara, A; Takemura, Y | 1 |
| Karasawa, T; Kuriyama, T; Nakagawa, K; Nakamura, S; Yamamoto, E | 1 |
| Furugo, I; Ishida, M; Takii, M; Ueda, M | 1 |
| Erdem, I; Goktas, P; Kaya, B; Kaynar-Tascioglu, J | 1 |
| Boulanger, BR; Fogarty, C; Fowler, C; Kahn, JB; Morgan, N; Oross, M; Tennenberg, A; West, M; Wiesinger, B; Wu, SC | 1 |
| Hata, K; Hisamori, S; Inoue, T; Ishimaru, H; Katoh, K; Maeda, Y; Maniwa, K; Minaguchi, M; Oida, K; Sakuramoto, M; Taguchi, Y; Tanaka, E; Terada, K | 1 |
| Burgess, DS; Frei, CR; Moczygemba, LR | 1 |
| Coker, A; Coker, C; Erkan, N; Onek, T; Sağol, O; Zeytunlu, M | 1 |
| Lister, PD; Wolter, DJ | 1 |
| Kollef, MH; Shorr, AF; Susla, GB | 1 |
| Jackson, WL; Kollef, MH; Ramage, AS; Shorr, AF; Tennenberg, AM; Wu, SC; Zadeikis, N | 1 |
| Engel, AE; Glass, D; Li, C; Wexler, HM | 1 |
| Lister, PD; Reisbig, MD; Wickman, PA; Wolter, DJ | 1 |
| Gómez Gómez, J; López Fornás, F; Lorente Salinas, I; Martínez García, F; Pérez Salmerón, J; Roldán Conesa, D; Ruiz Gómez, J; Segovia Hernández, M; Valdés Chávarri, M | 1 |
| Dowzicky, M; Kuti, JL; Nicolau, DP | 1 |
| Cox, JC; Drachman, DA; Hibbard, ML; Kopelman, TR; Maly, TJ; Matthews, MR; O'Neill, PJ; Quan, AN; Vail, SJ | 1 |
| Araj, GF; Awar, GN; Baban, TA; Kanj, SS; Naba, MR; Tabbarah, ZA | 1 |
| Fukuchi, K; Gomi, K; Takahashi, N; Wakuta, R; Yamaguchi, F | 1 |
| Goto, H; Higaki, M; Honda, K; Ishii, H; Mikura, S; Nakamura, M; Okazaki, M; Tsunoda, T; Wada, H; Watanabe, T; Yasutake, T | 1 |
| Kurtinecz, M; Li, G; Mitrani-Gold, FS; Mundy, LM; Singh, KP; Tomayko, JF; Wetherington, J | 1 |
| Bolac, C; Brassat, S; Camus, M; Cante, V; Guillet, G; Paquier-Valette, C | 1 |
| Gotoh, M; Katagiri, S; Nakamura, I; Ohyashiki, K; Yoshizawa, S | 1 |
| Galani, I; Giamarellos-Bourboulis, EJ; Pistiki, A; Safarika, A | 1 |
| Eksi, F; Nazli, E; Zer, Y | 1 |
| Li, J; Liu, Y; Wei, W; Yang, H; Ye, Y | 1 |
| Chen, TL; Chiu, CH; Fung, CP; Kuo, SC; Lee, YT; Lin, JC; Wang, FD; Wang, YC; Yang, YS; Yin, T | 1 |
| Badal, RE; Cao, B; Chen, S; Chu, Y; Duan, Q; Feng, X; Gui, B; Hu, B; Hu, Z; Huang, W; Kong, H; Liao, K; Luo, Y; Ni, Y; Shao, H; Su, J; Sun, Z; Wang, Y; Wu, A; Xu, Y; Yang, Q; Yu, Y; Zhang, H; Zhang, S | 1 |
| Hashiguchi, N; Inoshima, I; Inoshima, N | 1 |
| Ariza-Prota, MA; Budiño, T; Casan, P; Fole-Vázquez, D; García-Clemente, M; Pando-Sandoval, A | 1 |
| Aksaray, S; Avcıküçük, H; Başustaoğlu, A; Kaşkatepe, B; Süzük, S | 1 |
| Ahn, J; Jo, A | 1 |
| Hackel, MA; Hoban, DJ; Karlowsky, JA; Lob, SH; Sahm, DF | 1 |
| Gao, L; Li, Y; Lyu, Y | 1 |
| Bar-David, E; Ben-Shmuel, A; Brosh, T; Glinert, I; Kobiler, D; Levy, H; Schlomovitz, J; Sittner, A; Weiss, S | 1 |
| Ejaz, A; Ejaz, H; Javed, H; Saleem, R; Younas, S; Zafar, A | 1 |
| Chalhoub, H; Harding, SV; Tulkens, PM; Van Bambeke, F | 1 |
| Conterno, LO; Dayer, M; Gonzalez Garay, AG; Martí-Amarista, CE; Martí-Carvajal, AJ | 1 |
| Erber, J; Rothe, K; Schmid, RM; Schneider, J; Spinner, CD; Tschaikowsky, T; Weidlich, S | 1 |
| Dash, A; Gupta, N; Kodan, P; Ray, Y; Singh, BK; Soneja, M | 1 |
| Chander, J; Goel, A; Gupta, V; Palta, S; Singhal, L | 1 |
| Ardebili, A; Bagheri, H; Goharrizi, MASB; Hjimohammadi, A; Izanloo, A; Jamali, A; Shahri, FN | 1 |
| Bezruk, VV; Bulyk, TS; Buriak, OH; Godovanets, OS; Honcharuk, LM; Hresko, MD; Hresko, MM; Makarova, OV; Pervozvanska, OI; Rynzhuk, LV; Sheremet, MI; Shkrobanets, ID; Velia, MI; Voytkevich, NI; Yurkiv, OI; Yurniuk, SV | 1 |
| Al Atbee, MYN; Jalil, MB | 1 |
| Baba, T; Boucher, HW; Chambers, HF; Collyar, D; Dai, W; Doernberg, SB; Evans, SR; Fowler, VG; Gelone, SP; Hamasaki, T; Hill, C; Holland, TL; Howard-Anderson, J; Kinamon, T; Mariano, D; Nambiar, S; Rubin, D | 1 |
| Cheng, B; Guo, P; Jia, P; Xu, Y; Yang, Q; Zhang, H; Zhu, Y | 1 |
| Abbas Tikki, K; Hayder Hasan, T; Sabah Bustani, G; Sadeq Al-Ethari, A | 1 |
| Khan, M; Ma, K; Wan, I; Willcox, MD | 1 |
| Alcalá, FJC; Alonso, AR; Alonso, OZ; Calvo, C; de Villalta, MGF; García, LE; García-Boyano, M; Melero, IQ; Retolaza, IR | 1 |
| Álvarez-Pérez, S; Anega, B; Blanco, JL; García, ME; Hernández, M | 1 |
5 review(s) available for levofloxacin and imipenem, anhydrous
| Article | Year |
|---|---|
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Current scenario of tetrazole hybrids for antibacterial activity.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles | 2019 |
Quinolones for treatment of nosocomial pneumonia: a meta-analysis.
Topics: Anti-Infective Agents; Cilastatin; Ciprofloxacin; Cross Infection; Humans; Imipenem; Levofloxacin; Meta-Analysis as Topic; Ofloxacin; Pneumonia, Bacterial; Quinolones; Randomized Controlled Trials as Topic | 2005 |
Systematic review and meta-analysis of antimicrobial treatment effect estimation in complicated urinary tract infection.
Topics: Anti-Bacterial Agents; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Clinical Trials as Topic; Databases, Bibliographic; Doripenem; Drug Combinations; Female; Humans; Imipenem; Levofloxacin; Male; Research Design; Treatment Outcome; Urinary Tract Infections | 2013 |
A comparison of different antibiotic regimens for the treatment of infective endocarditis.
Topics: Anti-Bacterial Agents; Endocarditis, Bacterial; Female; Fosfomycin; Humans; Imipenem; Levofloxacin; Male; Penicillins; Randomized Controlled Trials as Topic; Vancomycin | 2020 |
3 trial(s) available for levofloxacin and imipenem, anhydrous
| Article | Year |
|---|---|
Levofloxacin in the empirical treatment of patients with suspected bacteraemia/sepsis: comparison with imipenem/cilastatin in an open, randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteremia; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Imipenem; Levofloxacin; Middle Aged; Ofloxacin; Protease Inhibitors; Sepsis; Thienamycins | 1999 |
Levofloxacin compared with imipenem/cilastatin followed by ciprofloxacin in adult patients with nosocomial pneumonia: a multicenter, prospective, randomized, open-label study.
Topics: Adult; Aged; Anti-Bacterial Agents; Cilastatin; Ciprofloxacin; Cross Infection; Drug Therapy, Combination; Female; Humans; Imipenem; Levofloxacin; Male; Middle Aged; Ofloxacin; Pneumonia, Bacterial; Pneumonia, Staphylococcal; Prospective Studies; Pseudomonas aeruginosa | 2003 |
Levofloxacin for treatment of ventilator-associated pneumonia: a subgroup analysis from a randomized trial.
Topics: Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Cross Infection; Double-Blind Method; Drug Combinations; Drug Resistance, Bacterial; Female; Humans; Imipenem; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pneumonia, Bacterial; Prospective Studies; Thienamycins; Treatment Outcome; Ventilators, Mechanical | 2005 |
108 other study(ies) available for levofloxacin and imipenem, anhydrous
| Article | Year |
|---|---|
Multistep resistance selection and postantibiotic-effect studies of the antipneumococcal activity of LBM415 compared to other agents.
Topics: Amidohydrolases; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Peptides; Pneumococcal Infections; Species Specificity; Streptococcus pneumoniae; Time Factors | 2007 |
First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Conjugation, Genetic; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Integrons; Latin America; Molecular Sequence Data; Plasmids | 2007 |
In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens.
Topics: Animals; Anti-Infective Agents; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Mice; Microbial Sensitivity Tests; Quinolones; Thiazoles | 2007 |
Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-beta-lactamase-producing Enterobacteriaceae: importance of inadequate initial antimicrobial treatment.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cross Infection; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Female; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged; Predictive Value of Tests; Proteus mirabilis; Risk Factors; Survival Analysis; Treatment Outcome | 2007 |
Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cross Infection; Humans; Italy; Microbial Sensitivity Tests | 2007 |
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital.
Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic | 2007 |
Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Ceftazidime; Colistin; Colony Count, Microbial; Drug Combinations; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests | 2007 |
Development of resistance in wild-type and hypermutable Pseudomonas aeruginosa strains exposed to clinical pharmacokinetic profiles of meropenem and ceftazidime simulated in vitro.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Ceftazidime; Colony Count, Microbial; DNA, Bacterial; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Enzyme Inhibitors; Genotype; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Mutation; Phenotype; Porins; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Thienamycins | 2007 |
Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals.
Topics: Acinetobacter; Acinetobacter Infections; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Blotting, Southern; Carbapenems; China; Chloramphenicol; Colistin; Cross Infection; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Hospitals; Humans; Imipenem; Integrons; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Rifampin; Sequence Analysis, DNA | 2007 |
Capability of 11 antipneumococcal antibiotics to select for resistance by multistep and single-step methodologies.
Topics: Anti-Bacterial Agents; Aza Compounds; Azithromycin; Clarithromycin; Clavulanic Acid; Clindamycin; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Imipenem; Ketolides; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Streptococcus pneumoniae | 2007 |
Antimicrobial susceptibilities and clinical sources of Dialister species.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Species Specificity; Veillonellaceae | 2007 |
RmtC 16S rRNA methyltransferase in Australia.
Topics: Aminoglycosides; Anti-Bacterial Agents; Australia; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Drug Resistance, Bacterial; Genes, rRNA; Humans; Methyltransferases; Microbial Sensitivity Tests; Proteus Infections; Proteus mirabilis; RNA, Ribosomal, 16S | 2008 |
AdeIJK, a resistance-nodulation-cell division pump effluxing multiple antibiotics in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Cloning, Molecular; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Sequence Analysis, DNA; Substrate Specificity | 2008 |
Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Ceftaroline; Cephalosporins; Community-Acquired Infections; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; United States | 2008 |
Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan.
Topics: Anti-Bacterial Agents; Conjugation, Genetic; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Fluoroquinolones; Hospitals; Humans; Japan; Microbial Sensitivity Tests; Plasmids; Prevalence | 2008 |
Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States.
Topics: Aged; Bacterial Proteins; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Quinolones; United States | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates.
Topics: Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacter cloacae; Genes, Bacterial; Microbial Sensitivity Tests; Plasmids; Quinolones | 2008 |
In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii and selection of tigecycline-amikacin synergy.
Topics: Acinetobacter baumannii; Amikacin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Microbial Sensitivity Tests; Minocycline; Tigecycline | 2008 |
Potent in vitro activity of tomopenem (CS-023) against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.
Topics: Carbapenems; Imipenem; Meropenem; Methicillin Resistance; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Thienamycins | 2008 |
Bloodstream infections caused by extended-spectrum-beta-lactamase- producing Escherichia coli: risk factors for inadequate initial antimicrobial therapy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Risk Factors; Treatment Failure | 2008 |
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Endemic Diseases; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; New York City; Sequence Analysis, DNA | 2008 |
In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; United States | 2008 |
Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; Blood; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Taiwan | 2008 |
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids | 2008 |
First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy.
Topics: Base Sequence; beta-Lactam Resistance; beta-Lactamases; Data Collection; DNA Primers; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Integrons; Italy; Molecular Epidemiology; Molecular Sequence Data | 2008 |
KPC-2-producing Enterobacter cloacae and pseudomonas putida coinfection in a liver transplant recipient.
Topics: Anti-Bacterial Agents; beta-Lactamases; Enterobacter cloacae; Female; Humans; Liver Transplantation; Microbial Sensitivity Tests; Middle Aged; Pseudomonas putida; RNA, Ribosomal, 16S | 2009 |
Establishment of in vitro susceptibility testing methodologies and comparative activities of piperacillin in combination with the penem {beta}-lactamase inhibitor BLI-489.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; beta-Lactamase Inhibitors; Drug Combinations; Enzyme Inhibitors; Humans; Lactams; Microbial Sensitivity Tests; Piperacillin | 2009 |
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog.
Topics: Animals; Anti-Bacterial Agents; Dogs; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Virulence | 2009 |
Characterization and sequence analysis of extended-spectrum-{beta}-lactamase-encoding genes from Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates collected during tigecycline phase 3 clinical trials.
Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactamases; Clinical Trials, Phase III as Topic; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Humans; Isoelectric Focusing; Klebsiella pneumoniae; Microbial Sensitivity Tests; Minocycline; Proteus mirabilis; Reverse Transcriptase Polymerase Chain Reaction; Tigecycline | 2009 |
Affinity of Tomopenem (CS-023) for penicillin-binding proteins in Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.
Topics: Carbapenems; Escherichia coli; Microbial Sensitivity Tests; Mutation; Penicillin-Binding Proteins; Pseudomonas aeruginosa; Staphylococcus aureus | 2009 |
In vitro antimicrobial activity of a new cephalosporin, ceftaroline, and determination of quality control ranges for MIC testing.
Topics: Anti-Bacterial Agents; Ceftaroline; Ceftriaxone; Cephalosporins; Culture Media; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quality Control | 2009 |
Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Chromosome Walking; DNA-Binding Proteins; Genetic Engineering; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Point Mutation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2009 |
Comparative antipneumococcal activities of sulopenem and other drugs.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Lactams; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Streptococcus pneumoniae | 2009 |
Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; China; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Imipenem; India; Klebsiella; Quinolones; Thailand | 2009 |
Besifloxacin, a novel fluoroquinolone, has broad-spectrum in vitro activity against aerobic and anaerobic bacteria.
Topics: Anti-Bacterial Agents; Azepines; Bacteria, Anaerobic; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests | 2009 |
Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.
Topics: Computational Biology; Computer Simulation; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ligands; Penicillin-Binding Proteins; Protein Binding; Streptococcus pneumoniae; Structure-Activity Relationship | 2009 |
Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence.
Topics: Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Culture Media; Defensins; DNA, Bacterial; Drug Resistance, Bacterial; Genotype; Humans; Klebsiella Infections; Klebsiella pneumoniae; Lipopolysaccharides; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Phenotype; Plasmids; Polymyxin B; Polysaccharides; Repressor Proteins; RNA, Bacterial | 2010 |
In vitro potency of CXA-101, a novel cephalosporin, against Pseudomonas aeruginosa displaying various resistance phenotypes, including multidrug resistance.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Young Adult | 2010 |
Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Cations, Monovalent; Culture Media; Drug Resistance, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Proteomics; Sodium Chloride; Virulence Factors | 2010 |
Detection of KPC in Acinetobacter spp. in Puerto Rico.
Topics: Acinetobacter; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; beta-Lactam Resistance; beta-Lactamases; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Population Surveillance; Puerto Rico | 2010 |
Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents.
Topics: Anti-Bacterial Agents; Campylobacter coli; Campylobacter Infections; Campylobacter jejuni; Carbapenems; Drug Resistance, Multiple, Bacterial; Erythromycin; Feces; Finland; Humans; Macrolides; Microbial Sensitivity Tests; Minocycline; Tigecycline | 2010 |
Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates.
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Quinolines; Quinolones; Taiwan | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Aminoglycosides; beta-Lactamases; Carbapenems; Cephalosporins; DNA Gyrase; Drug Resistance, Bacterial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Taiwan | 2010 |
Worldwide experience with the use of doripenem against extended-spectrum-beta-lactamase-producing and ciprofloxacin-resistant Enterobacteriaceae: analysis of six phase 3 clinical studies.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Ciprofloxacin; Clinical Trials, Phase III as Topic; Doripenem; Enterobacteriaceae; Enterobacteriaceae Infections; Global Health; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prevalence | 2010 |
Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008.
Topics: Academic Medical Centers; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Humans; In Vitro Techniques; Israel; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Time Factors | 2010 |
Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Communicable Diseases, Emerging; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States | 2010 |
Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; Israel; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology; Phylogeny; Plasmids; Polymerase Chain Reaction | 2010 |
In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center.
Topics: Acinetobacter baumannii; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Dibekacin; Hospitals, Military; Humans; Microbial Sensitivity Tests; Warfare | 2010 |
Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob
Topics: Abdomen; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cross Infection; Escherichia coli; Escherichia coli Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae | 2010 |
Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART).
Topics: Abdomen; Amikacin; beta-Lactams; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Ertapenem; Escherichia coli; Gram-Negative Bacteria; Humans; Imipenem; Microbial Sensitivity Tests | 2010 |
In vitro antimicrobial activity and mutant prevention concentration of colistin against Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Colistin; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Mutation | 2010 |
Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates.
Topics: Anti-Bacterial Agents; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests | 2010 |
The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins.
Topics: Anti-Infective Agents; Bacterial Proteins; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Two-Dimensional; Methylmalonate-Semialdehyde Dehydrogenase (Acylating); Microbial Sensitivity Tests; Pseudomonas aeruginosa; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinate-Semialdehyde Dehydrogenase | 2010 |
Overexpression of the adeB gene in clinical isolates of tigecycline-nonsusceptible Acinetobacter baumannii without insertion mutations in adeRS.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Aged; Aged, 80 and over; Bacterial Proteins; Carbapenems; Drug Resistance, Bacterial; Female; Humans; Male; Membrane Transport Proteins; Middle Aged; Minocycline; Molecular Sequence Data; Mutagenesis, Insertional; Reverse Transcriptase Polymerase Chain Reaction; Tigecycline | 2010 |
In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; Carbapenems; Drug Resistance, Bacterial; Fatal Outcome; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
In vitro efficacy of levofloxacin alone or in combination tested against multi-resistant Pseudomonas aeruginosa strains.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Ciprofloxacin; Drug Resistance, Multiple; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Piperacillin; Pseudomonas aeruginosa; Tobramycin | 1996 |
[Isolation rate of Enterococcus spp. from surgical infections and their susceptibilities].
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Microbial; Enterococcus; Humans; Imipenem; Levofloxacin; Ofloxacin; Penicillins; Surgical Wound Infection; Thienamycins; Time Factors; Vancomycin | 1997 |
[Legionella pneumonia successfully treated despite late diagnosis].
Topics: Administration, Oral; Aged; Anti-Infective Agents; Cilastatin; Drug Combinations; Humans; Imipenem; Legionnaires' Disease; Levofloxacin; Male; Ofloxacin; Protease Inhibitors; Thienamycins | 1997 |
In vitro antibacterial activity of LJC 11,036, an active metabolite of L-084, a new oral carbapenem antibiotic with potent antipneumococcal activity.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Carrier Proteins; Cefdinir; Cephalosporins; Dipeptidases; Drug Stability; Escherichia coli Proteins; Hexosyltransferases; Imipenem; Lactams; Levofloxacin; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Ofloxacin; Penicillin-Binding Proteins; Peptidoglycan Glycosyltransferase; Peptidyl Transferases; Protein Binding; Serine-Type D-Ala-D-Ala Carboxypeptidase; Thienamycins | 1999 |
In vivo activity of levofloxacin alone or in combination with imipenem or amikacin in a mouse model of Acinetobacter baumannii pneumonia.
Topics: Acinetobacter Infections; Amikacin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Area Under Curve; Disease Models, Animal; Drug Therapy, Combination; Female; Imipenem; Levofloxacin; Mice; Mice, Inbred C3H; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Bacterial; Thienamycins | 2000 |
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture].
Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefixime; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Japan; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillin G; Penicillins; Streptococcus pneumoniae; Thienamycins | 2000 |
[Mycobacterium abscessus infection complicated with diabetes mellitus].
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Diabetes Complications; Drug Combinations; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Male; Mycobacterium Infections, Nontuberculous; Ofloxacin; Tuberculosis, Pulmonary | 2002 |
Bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections.
Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Cefazolin; Cefotaxime; Cephalosporins; Clindamycin; Corynebacterium; Drug Resistance, Bacterial; Erythromycin; Eubacterium; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Imipenem; Levofloxacin; Ofloxacin; Penicillins; Peptostreptococcus; Periodontitis; Staphylococcus; Streptococcus; Sulbactam; Thienamycins; Tooth Diseases | 2002 |
[Microbiological and clinical studies of Haemophilus influenzae isolated at Kitakyushu Municipal Medical Center from 1996 through 1999].
Topics: Adult; Aged; Ampicillin; Anti-Infective Agents; beta-Lactamases; Cefaclor; Cephalosporins; Child, Preschool; Female; Haemophilus influenzae; Humans; Imipenem; Infant; Infant, Newborn; Levofloxacin; Male; Meningitis, Bacterial; Meropenem; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Respiratory System; Seasons; Sulbactam; Thienamycins | 2002 |
The comparison of in the vitro effect of imipenem or meropenem combined with ciprofloxacin or levofloxacin against multidrug-resistant Pseudomonas aeruginosa strains.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 2002 |
[A case of pulmonaly bulla infection with Mycobacterium fortuitum].
Topics: Aged; Blister; Cilastatin; Cilastatin, Imipenem Drug Combination; Clarithromycin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Levofloxacin; Lung Diseases, Interstitial; Minocycline; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Ofloxacin; Pulmonary Emphysema | 2003 |
Pharmacodynamic modeling of carbapenems and fluoroquinolones against bacteria that produce extended-spectrum beta-lactamases.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Ertapenem; Escherichia coli; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Klebsiella pneumoniae; Lactams; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Ofloxacin; Thienamycins | 2004 |
Effects of selected antibiotics on pancreatitis induced liver and pulmonary injury.
Topics: Acute Disease; Alanine Transaminase; Amylases; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Imipenem; L-Lactate Dehydrogenase; Levofloxacin; Liver; Liver Diseases; Lung; Lung Diseases; Male; Nitric Oxide; Ofloxacin; Pancreatitis; Rats; Rats, Wistar | 2005 |
Levofloxacin-imipenem combination prevents the emergence of resistance among clinical isolates of Pseudomonas aeruginosa.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections | 2005 |
In vitro activities of doripenem and comparator agents against 364 anaerobic clinical isolates.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; beta-Lactams; Carbapenems; Doripenem; Ertapenem; Humans; Imipenem; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Ofloxacin; Thienamycins | 2005 |
Levofloxacin/imipenem prevents the emergence of high-level resistance among Pseudomonas aeruginosa strains already lacking susceptibility to one or both drugs.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Synergism; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa | 2006 |
[Comparative study of treatment with quinupristin-dalfopristin alone or in combination with gentamicin, teicoplanin, imipenem or levofloxacin in experimental endocarditis due to a multidrug-resistant Enterococcus faecium].
Topics: Aged; Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecium; Female; Gentamicins; Gram-Positive Bacterial Infections; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Rabbits; Teicoplanin; Virginiamycin | 2006 |
A pharmacodynamic simulation to assess tigecycline efficacy for hospital-acquired pneumonia compared with other common intravenous antibiotics.
Topics: Anti-Bacterial Agents; Cross Infection; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Models, Biological; Monte Carlo Method; Ofloxacin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Tigecycline | 2008 |
Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tobramycin | 2010 |
Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Clarithromycin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Lebanon; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Vancomycin | 2010 |
[Validity of using imipenem as a representative carbapenems and levofloxacin as a representative fluoroquinolones in antibiotics susceptibility test for enterobacteriaceae].
Topics: Anti-Bacterial Agents; Carbapenems; Drug Resistance, Bacterial; Enterobacteriaceae; Fluoroquinolones; Imipenem; Levofloxacin; Ofloxacin | 2011 |
Risk factors for bacteraemia attributable to Pseudomonas aeruginosa resistant to imipenem, levofloxacin, or gentamicin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Female; Gentamicins; Humans; Imipenem; Infant; Infant, Newborn; Levofloxacin; Male; Middle Aged; Ofloxacin; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Young Adult | 2011 |
[Endogenous endophthalmitis as a complication in erysipelas].
Topics: Antifungal Agents; Bacteremia; Ceftazidime; Diabetes Mellitus, Type 2; Disease Susceptibility; Drug Therapy, Combination; Endophthalmitis; Erysipelas; Eye Infections, Bacterial; Humans; Imipenem; Intertrigo; Leg; Levofloxacin; Male; Middle Aged; Obesity; Streptococcus agalactiae; Uveitis, Anterior; Vancomycin | 2013 |
[Case report; Disseminated Mycobacterium abscessus infection with hemophagocytic syndrome during treatment of chronic lymphocytic leukemia].
Topics: Amikacin; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Clarithromycin; Cyclophosphamide; Humans; Imipenem; Immunocompromised Host; Immunoglobulins, Intravenous; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Levofloxacin; Lymphohistiocytosis, Hemophagocytic; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Opportunistic Infections; Prednisolone; Treatment Outcome | 2014 |
Time-kill effect of levofloxacin on multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii: synergism with imipenem and colistin.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Colistin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Pseudomonas Infections; Time Factors | 2015 |
In vitro efficacy of various antibiotic combinations against Pseudomonas aeruginosa isolates.
Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Colistin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Microbial Viability; Pseudomonas aeruginosa; Pseudomonas Infections | 2015 |
In vitro synergy of colistin combinations against extensively drug-resistant Acinetobacter baumannii producing OXA-23 carbapenemase.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Colistin; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Fosfomycin; Humans; Imipenem; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Polymerase Chain Reaction; Rifampin; Sulbactam | 2016 |
A retrospective study of the incidence, clinical characteristics, identification, and antimicrobial susceptibility of bacteremic isolates of Acinetobacter ursingii.
Topics: Acinetobacter; Acinetobacter Infections; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Ceftazidime; Ceftriaxone; Electrophoresis, Gel, Pulsed-Field; Female; Genotype; Humans; Imipenem; Incidence; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Phenotype; Retrospective Studies; RNA, Ribosomal, 16S | 2015 |
Antimicrobial Susceptibilities of Aerobic and Facultative Gram-Negative Bacilli from Intra-abdominal Infections in Patients from Seven Regions in China in 2012 and 2013.
Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefoxitin; China; Ciprofloxacin; Community-Acquired Infections; Cross Infection; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Gene Expression; Humans; Imipenem; Intraabdominal Infections; Levofloxacin; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam | 2016 |
[A CASE OF PULMONARY MYCOBACTERIUM ABSCESSUS INFECTION SUCCESSFULLY TREATED WITH SHORT-TERM CAM, AMK, AND IPM/cs FOLLOWED BY LONG-TERM ORAL CAM AND LVFX].
Topics: Administration, Oral; Aged; Amikacin; Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Clarithromycin; Drug Combinations; Female; Humans; Imipenem; Levofloxacin; Lung Diseases; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria | 2015 |
Community-acquired bacteremic Streptomyces atratus pneumonia in animmunocompetent adult: a case report.
Topics: Actinomycetales Infections; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Bronchoscopy; Community-Acquired Infections; Humans; Imipenem; Immunocompetence; Levofloxacin; Male; Pneumonia, Bacterial; Sequence Analysis, DNA; Streptomyces; Treatment Outcome | 2015 |
[The comparison of antibiotic susceptibilities of uropathogenic Escherichia coli isolates in transition from CLSI to EUCAST].
Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Bacteriuria; Cefuroxime; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Drug Resistance, Bacterial; Escherichia coli Infections; European Union; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Reference Standards; Sulbactam; Trimethoprim, Sulfamethoxazole Drug Combination; Turkey; Urinary Tract Infections; Uropathogenic Escherichia coli | 2015 |
Phenotypic and genotypic characterisation of multiple antibiotic-resistant Staphylococcus aureus exposed to subinhibitory levels of oxacillin and levofloxacin.
Topics: Adhesins, Bacterial; Bacterial Adhesion; Bacterial Proteins; beta-Lactamases; Biofilms; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Coagulase; Dipeptides; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genotype; Imipenem; Levofloxacin; Membrane Transport Proteins; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxacillin; Phenotype; Polymerase Chain Reaction; Staphylococcus aureus; Streptomycin | 2016 |
Antimicrobial susceptibility of Gram-negative ESKAPE pathogens isolated from hospitalized patients with intra-abdominal and urinary tract infections in Asia-Pacific countries: SMART 2013-2015.
Topics: Acinetobacter baumannii; Amikacin; Anti-Infective Agents; Asia; beta-Lactamases; beta-Lactams; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacter; Ertapenem; Gram-Negative Bacteria; Hospitalization; Humans; Imipenem; Intraabdominal Infections; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Urinary Tract Infections | 2017 |
Trends in Drug Resistance of
Topics: Acinetobacter baumannii; Amikacin; Anti-Infective Agents; Cefepime; Cefoperazone; Ceftazidime; Cephalosporins; China; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam | 2017 |
Treating Anthrax-Induced Meningitis in Rabbits.
Topics: Animals; Anthrax; Anti-Bacterial Agents; Antitoxins; Bacillus anthracis; Central Nervous System; Ciprofloxacin; Clindamycin; Dexamethasone; Disease Models, Animal; Drug Combinations; Imipenem; Levofloxacin; Linezolid; Meningitis, Bacterial; Meropenem; Rabbits; Treatment Failure | 2018 |
AmpC beta-lactamases in Klebsiella pneumoniae: An emerging threat to the paediatric patients.
Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefoperazone; Cefoxitin; Cephalosporins; Child; Child, Preschool; Ciprofloxacin; Cross-Sectional Studies; Disk Diffusion Antimicrobial Tests; Drug Combinations; Drug Resistance, Bacterial; Female; Hospitals, Pediatric; Humans; Imipenem; Infant; Infant, Newborn; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Male; Meropenem; Microbial Sensitivity Tests; Pakistan; Piperacillin, Tazobactam Drug Combination; Sulbactam | 2018 |
Influence of pH on the activity of finafloxacin against extracellular and intracellular Burkholderia thailandensis, Yersinia pseudotuberculosis and Francisella philomiragia and on its cellular pharmacokinetics in THP-1 monocytes.
Topics: Anti-Bacterial Agents; Burkholderia; Fluoroquinolones; Francisella; Humans; Hydrogen-Ion Concentration; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Monocytes; THP-1 Cells; Yersinia pseudotuberculosis | 2020 |
Successful bedaquiline-containing antimycobacterial treatment in post-traumatic skin and soft-tissue infection by Mycobacterium fortuitum complex: a case report.
Topics: Amikacin; Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Female; Humans; Imipenem; Levofloxacin; Macrolides; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Skin; Skin Diseases, Bacterial; Soft Tissue Infections; Soft Tissue Injuries; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Vietnam; Young Adult | 2020 |
Choosing the therapy for neurological infection with rapidly growing mycobacteria.
Topics: Administration, Intravenous; Adolescent; Amikacin; Central Nervous System Bacterial Infections; Clinical Decision-Making; Female; Humans; Imipenem; Levofloxacin; Linezolid; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Ventriculoperitoneal Shunt | 2020 |
Topics: Anti-Bacterial Agents; Carbapenem-Resistant Enterobacteriaceae; Colistin; Humans; Imipenem; Klebsiella pneumoniae; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Polymyxin B; Tigecycline | 2021 |
Antimicrobial resistance, virulence factors, and genotypes of Pseudomonas aeruginosa clinical isolates from Gorgan, northern Iran.
Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Colistin; Deoxyribonucleases; Drug Resistance, Bacterial; Genotype; Gentamicins; Humans; Imipenem; Iran; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Pancreatic Elastase; Phospholipases; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin; Virulence Factors | 2022 |
Management of antibacterial therapy of infectious and inflammatory diseases of the urinary tract in children and regional peculiarities during the COVID-19 pandemic.
Topics: Adolescent; Anti-Bacterial Agents; Carbapenems; Child; Child, Preschool; COVID-19 Drug Treatment; Doxycycline; Humans; Imipenem; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Pandemics; Urinary Tract; Urinary Tract Infections | 2022 |
The prevalence of multiple drug resistance Escherichia coli and Klebsiella pneumoniae isolated from patients with urinary tract infections.
Topics: Ampicillin; Anti-Bacterial Agents; Aztreonam; Cefepime; Ceftazidime; Ceftriaxone; Ciprofloxacin; Drug Resistance, Multiple; Escherichia coli; Escherichia coli Infections; Gentamicins; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Piperacillin; Prevalence; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 2022 |
Improving Traditional Registrational Trial End Points: Development and Application of a Desirability of Outcome Ranking End Point for Complicated Urinary Tract Infection Clinical Trials.
Topics: Anti-Bacterial Agents; Doripenem; Humans; Imipenem; Levofloxacin; Urinary Tract Infections | 2023 |
In vitro activity of ceftaroline, ceftazidime-avibactam, and comparators against Gram-positive and -negative organisms in China: the 2018 results from the ATLAS program.
Topics: Ampicillin; Anti-Bacterial Agents; Azabicyclo Compounds; Ceftaroline; Ceftazidime; Cephalosporins; Colistin; Drug Combinations; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Imipenem; Klebsiella pneumoniae; Levofloxacin; Meropenem; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Piperacillin; Tazobactam; Tigecycline | 2022 |
Genotypic Detection of
Topics: Agar; Amikacin; Anti-Bacterial Agents; Ceftazidime; Ceftriaxone; Ciprofloxacin; Citrobacter koseri; Gentamicins; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Urinary Tract Infections | 2022 |
Ciprofloxacin resistance and tolerance of Pseudomonas aeruginosa ocular isolates.
Topics: Agar; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Gentamicins; Humans; Imipenem; Keratitis; Levofloxacin; Microbial Sensitivity Tests; Piperacillin; Polymyxin B; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2023 |
Microbiological patterns of bacterial infections in tracheostomized children: Reducing uncertainty in continuous care.
Topics: Adolescent; Anti-Bacterial Agents; Child; Drug Resistance, Bacterial; Escherichia coli; Follow-Up Studies; Humans; Imipenem; Klebsiella pneumoniae; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Respiratory Tract Infections; Retrospective Studies; Staphylococcal Infections; Uncertainty | 2023 |
In vitro activity of fidaxomicin and combinations of fidaxomicin with other antibiotics against Clostridium perfringens strains isolated from dogs and cats.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clindamycin; Clostridioides difficile; Clostridium Infections; Clostridium perfringens; Diarrhea; Dog Diseases; Dogs; Erythromycin; Fidaxomicin; Humans; Imipenem; Levofloxacin; Metronidazole; Microbial Sensitivity Tests; Vancomycin | 2023 |