Page last updated: 2024-09-04

levofloxacin and eye

levofloxacin has been researched along with eye in 16 studies

Compound Research Comparison

Studies
(levofloxacin)
Trials
(levofloxacin)
Recent Studies (post-2010)
(levofloxacin)
Studies
(eye)
Trials
(eye)
Recent Studies (post-2010) (eye)
4,3465812,20941,7167248,737

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's4 (25.00)29.6817
2010's9 (56.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Jin, Y; Mochizuki, K; Ohkubo, S; Okamura, Y; Tanahashi, T; Tanaka, M; Torisaki, M; Yamashita, Y1
Bandello, F; Ferrari, E; Furlanut, M; Pavan, F; Pea, F; Roman-Pognuz, D1
Guo, H; Li, J; Liu, Z; Nie, S; Pan, W1
Bai, XQ; Deng, SJ; Li, L; Li, R; Liang, QF; Luo, SY; Sun, XG; Wang, ZQ1
Choi, JS; Joo, CK; Kim, KA; Lim, JA; Park, SH1
Chen, H; Jiang, HR; Wu, XG; Xin, M; Yang, LN1
Chen, H; Jiang, H; Liu, T; Song, Z; Wu, X; Xu, Y; Yang, L; Yue, W1
Chen, ZJ; Han, L; Sun, ST; Wang, LY; Yue, J; Zhang, YQ1
Allouche, S; Dabboussi, F; Hamze, M; Mallat, H1
Colaço, R; Fernandes, AI; Galante, R; Mata, JL; Matos, AP; Moutinho, MG; Paradiso, P; Saramago, B; Serro, AP1
Ahad, A; Ali, A; Aqil, M; Aslam, M; Baig, MS; Imam, SS1
Lei, L; Li, X; Song, Z; Xiong, T; Yu, J; Yu, X1
Bao, Z; Lei, L; Li, X; Lin, D; Liu, H; Shi, H; Wang, Y; Xu, X; Yu, A1
Chen, WD; Hsu, WH; Huang, TY; Lai, LJ1
Bao, Z; Dai, M; Hu, Y; Jin, B; Lei, L; Li, X; Lin, D; Shi, H; Wang, Y; Yu, A1
AlQaraghuli, F; Babiskin, A; Le Merdy, M; Lukacova, V; Tan, ML; Walenga, R; Zhao, L1

Trials

1 trial(s) available for levofloxacin and eye

ArticleYear
Levofloxacin disposition over time in aqueous humor of patients undergoing cataract surgery.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aqueous Humor; Cataract Extraction; Endophthalmitis; Eye; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Time Factors

2005

Other Studies

15 other study(ies) available for levofloxacin and eye

ArticleYear
[Intraocular penetration of oral levofloxacin in rabbits].
    Nippon Ganka Gakkai zasshi, 1994, Volume: 98, Issue:11

    Topics: Administration, Oral; Albinism, Ocular; Animals; Autoradiography; Eye; Levofloxacin; Melanins; Ofloxacin; Rabbits; Tissue Distribution

1994
Effects of Transcutol P on the corneal permeability of drugs and evaluation of its ocular irritation of rabbit eyes.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:1

    Topics: 1-Octanol; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cornea; Drug Carriers; Enoxacin; Ethylene Glycols; Eye; Fluoroquinolones; Gatifloxacin; In Vitro Techniques; Irritants; Levofloxacin; Ofloxacin; Oxaprozin; Permeability; Propionates; Rabbits; Ribavirin; Water

2006
[Analysis on susceptibility of ocular bacterial pathogens to four kinds of fluoroquinolone].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2008, Volume: 44, Issue:3

    Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Eye; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin

2008
The resistance patterns of normal ocular bacterial flora to 4 fluoroquinolone antibiotics.
    Cornea, 2009, Volume: 28, Issue:1

    Topics: Anti-Bacterial Agents; Aza Compounds; Bacteria; Bacteria, Aerobic; Ciprofloxacin; Conjunctiva; Eye; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Ofloxacin; Quinolines

2009
Novel mucoadhesive polysaccharide isolated from Bletilla striata improves the intraocular penetration and efficacy of levofloxacin in the topical treatment of experimental bacterial keratitis.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:9

    Topics: Absorption; Administration, Topical; Animals; Anti-Bacterial Agents; Aqueous Humor; Bacterial Load; Biological Availability; Cell Line; Cell Proliferation; Cornea; Disease Models, Animal; Endothelial Cells; Eye; Female; Humans; Keratitis; Levofloxacin; Male; Ofloxacin; Ophthalmic Solutions; Orchidaceae; Plant Extracts; Polysaccharides; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tears; Treatment Outcome

2010
Efficacy of gemifloxacin for the treatment of experimental Staphylococcus aureus keratitis.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Animals; Anti-Infective Agents, Local; Colony Count, Microbial; Conjunctival Diseases; Cornea; Eye; Female; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Keratitis; Levofloxacin; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Rabbits; Staphylococcal Infections; Staphylococcus aureus

2012
[The changes of ocular bacterial isolates and in vitro antimicrobial susceptibility in the past six years].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2012, Volume: 48, Issue:6

    Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Eye; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Retrospective Studies; Staphylococcus epidermidis; Tobramycin

2012
Prevalence of first-step mutants among levofloxacin-susceptible isolates of Streptococcus pneumoniae in north Lebanon.
    Journal of chemotherapy (Florence, Italy), 2013, Volume: 25, Issue:6

    Topics: Blood; Drug Resistance, Bacterial; Ear; Eye; Fluoroquinolones; Humans; Lebanon; Levofloxacin; Lung; Microbial Sensitivity Tests; Mutation; Nose; Pneumococcal Infections; Prevalence; Streptococcus pneumoniae

2013
About the effect of eye blinking on drug release from pHEMA-based hydrogels: an in vitro study.
    Journal of biomaterials science. Polymer edition, 2015, Volume: 26, Issue:4

    Topics: Anti-Bacterial Agents; Blinking; Contact Lenses, Hydrophilic; Drug Delivery Systems; Drug Liberation; Elastic Modulus; Eye; Friction; Hydrogels; Levofloxacin; Models, Biological; Models, Chemical; Permeability; Polyhydroxyethyl Methacrylate; Pseudomonas aeruginosa; Staphylococcus aureus; Tears; Water; Wettability

2015
Application of Box-Behnken design for preparation of levofloxacin-loaded stearic acid solid lipid nanoparticles for ocular delivery: Optimization, in vitro release, ocular tolerance, and antibacterial activity.
    International journal of biological macromolecules, 2016, Volume: 85

    Topics: Animals; Anti-Bacterial Agents; Calorimetry, Differential Scanning; Chickens; Disk Diffusion Antimicrobial Tests; Drug Carriers; Drug Delivery Systems; Drug Liberation; Eye; Levofloxacin; Lipids; Nanoparticles; Ophthalmic Solutions; Particle Size; Permeability; Solubility; Stearic Acids; X-Ray Diffraction

2016
Covalently Cross-Linked Chitosan Hydrogel Sheet for Topical Ophthalmic Delivery of Levofloxacin.
    Journal of biomedical nanotechnology, 2018, Feb-01, Volume: 14, Issue:2

    Topics: Chitosan; Eye; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Levofloxacin; Polyethylene Glycols

2018
Thermosensitive glycol chitosan-based hydrogel as a topical ocular drug delivery system for enhanced ocular bioavailability.
    International journal of pharmaceutics, 2019, Oct-30, Volume: 570

    Topics: Animals; Biological Availability; Cell Line; Chitosan; Drug Delivery Systems; Drug Liberation; Eye; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Levofloxacin; Ophthalmic Solutions; Rabbits; Temperature

2019
Vibrio cholerae non-O1 - the first reported case of keratitis in a healthy patient.
    BMC infectious diseases, 2019, Oct-29, Volume: 19, Issue:1

    Topics: Administration, Topical; Amikacin; Anti-Bacterial Agents; Aquatic Organisms; Corneal Ulcer; Eye; Humans; Keratitis; Levofloxacin; Male; Middle Aged; Polymerase Chain Reaction; Seawater; Treatment Outcome; Vibrio cholerae non-O1; Vibrio Infections

2019
Glycol chitosan/oxidized hyaluronic acid hydrogel film for topical ocular delivery of dexamethasone and levofloxacin.
    International journal of biological macromolecules, 2021, Jan-15, Volume: 167

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Chemical Phenomena; Chitosan; Cornea; Dexamethasone; Drug Carriers; Drug Delivery Systems; Drug Liberation; Eye; Hyaluronic Acid; Hydrogels; Levofloxacin; Mice; Microbial Sensitivity Tests; Molecular Structure; Oxidation-Reduction; RAW 264.7 Cells

2021
Clinical Ocular Exposure Extrapolation for Ophthalmic Solutions Using PBPK Modeling and Simulation.
    Pharmaceutical research, 2023, Volume: 40, Issue:2

    Topics: Animals; Eye; Humans; Levofloxacin; Models, Biological; Ophthalmic Solutions; Rabbits

2023