Page last updated: 2024-09-04

levofloxacin and cefdinir

levofloxacin has been researched along with cefdinir in 18 studies

Compound Research Comparison

Studies
(levofloxacin)
Trials
(levofloxacin)
Recent Studies (post-2010)
(levofloxacin)
Studies
(cefdinir)
Trials
(cefdinir)
Recent Studies (post-2010) (cefdinir)
4,3465812,20933010
4,3465812,2092725068

Protein Interaction Comparison

ProteinTaxonomylevofloxacin (IC50)cefdinir (IC50)
SUMO-1Homo sapiens (human)6.25
low molecular weight phosphotyrosine protein phosphatase isoform cHomo sapiens (human)19.6
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1Homo sapiens (human)4.48

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's12 (66.67)29.6817
2010's3 (16.67)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Appelbaum, PC; Credito, KL; DeWasse, B; Kosowska-Shick, K; McGhee, P; Pankuch, GA1
Brown, SD; Critchley, IA; Janjic, N; Tillotson, GS; Traczewski, MM1
Brown, SD; Critchley, IA; Jacobs, MR; Janjic, N; Tillotson, GS; Traczewski, MM1
Appelbaum, PC; Ednie, LM; Kosowska-Shick, K; McGhee, P1
Iwata, S; Murayama, SY; Nakayama, E; Sakata, H; Seki, C; Sunakawa, K; Sunaoshi, K; Ubukata, K1
Distèche-Nguyen, M; Gerards, T; Luxen, A; Miguet, L; Pasha, FA; Thomas, A; Zervosen, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hikida, M; Igarashi, A; Itahashi, K; Kitamura, M; Shiba, T1
Hirai, K; Hiramatsu, K; Kishi, K; Murakami, J; Nasu, M; Yamasaki, T1
Ishii, Y; Miyazaki, S; Okamoto, H; Tateda, K; Yamaguchi, K1
Hashido, H; Ishigo, S; Iwata, I; Matsubara, S; Matsukawa, Y; Mikamo, H; Sawamura, H; Suematsu, H; Tamaya, T1
Hasegawa, M; Kobayashi, I; Matsuzaki, K; Sato, Y; Shikano, M; Watabe, E; Yoshimori, K1
Hasegawa, M; Kobayashi, I; Matsuzaki, K; Sato, Y; Shikano, M; Watabe, E; Yamanaka, N; Yoshimori, K1
Busman, TA; Henry, DC; Kapral, D; Paris, MM1
Fujisawa, M; Kitagawa, K; Nomi, M; Shigemura, K; Takami, N; Yamada, N1
Crawford, SB; Davis, WH; Geno, KA; Magee, MR; Monks, SM1

Reviews

1 review(s) available for levofloxacin and cefdinir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for levofloxacin and cefdinir

ArticleYear
Cefdinir versus levofloxacin in patients with acute rhinosinusitis of presumed bacterial etiology: a multicenter, randomized, double-blind study.
    Clinical therapeutics, 2004, Volume: 26, Issue:12

    Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Cefdinir; Cephalosporins; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Severity of Illness Index; Sinusitis; Treatment Outcome

2004

Other Studies

16 other study(ies) available for levofloxacin and cefdinir

ArticleYear
Multistep resistance selection and postantibiotic-effect studies of the antipneumococcal activity of LBM415 compared to other agents.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Amidohydrolases; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Peptides; Pneumococcal Infections; Species Specificity; Streptococcus pneumoniae; Time Factors

2007
National and regional assessment of antimicrobial resistance among community-acquired respiratory tract pathogens identified in a 2005-2006 U.S. Faropenem surveillance study.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Infections; beta-Lactams; Community-Acquired Infections; Drug Resistance, Multiple, Bacterial; Geography; Haemophilus influenzae; Health Surveys; Humans; Moraxella catarrhalis; Penicillin Resistance; Respiratory Tract Infections; Streptococcus pneumoniae; Trimethoprim, Sulfamethoxazole Drug Combination; United States

2007
Prevalence of serotype 19A Streptococcus pneumoniae among isolates from U.S. children in 2005-2006 and activity of faropenem.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Adolescent; Anti-Bacterial Agents; beta-Lactams; Child; Child, Preschool; Drug Resistance, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Phenotype; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States

2008
Comparative antipneumococcal activities of sulopenem and other drugs.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Lactams; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Streptococcus pneumoniae

2009
Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Aged; Bacterial Capsules; Child; Child, Preschool; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Infant; Infant, Newborn; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Polymerase Chain Reaction; Streptococcus agalactiae

2009
Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Computational Biology; Computer Simulation; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ligands; Penicillin-Binding Proteins; Protein Binding; Streptococcus pneumoniae; Structure-Activity Relationship

2009
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
In vitro antibacterial activity of LJC 11,036, an active metabolite of L-084, a new oral carbapenem antibiotic with potent antipneumococcal activity.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Carrier Proteins; Cefdinir; Cephalosporins; Dipeptidases; Drug Stability; Escherichia coli Proteins; Hexosyltransferases; Imipenem; Lactams; Levofloxacin; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Ofloxacin; Penicillin-Binding Proteins; Peptidoglycan Glycosyltransferase; Peptidyl Transferases; Protein Binding; Serine-Type D-Ala-D-Ala Carboxypeptidase; Thienamycins

1999
Macrolides and clindamycin suppress the release of Shiga-like toxins from Escherichia coli O157:H7 in vitro.
    International journal of antimicrobial agents, 2000, Volume: 15, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bacterial Toxins; Cefdinir; Cephalosporins; Chlorocebus aethiops; Clindamycin; Dose-Response Relationship, Drug; Escherichia coli O157; Fosfomycin; Humans; Latex Fixation Tests; Levofloxacin; Microbial Sensitivity Tests; Miocamycin; Ofloxacin; Roxithromycin; Shiga Toxin 1; Shiga Toxin 2; Time Factors; Vero Cells

2000
Comparative in vitro activity of telithromycin (HMR 3647), three macrolides, amoxycillin, cefdinir and levofloxacin against gram-positive clinical isolates in Japan.
    The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:5

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefdinir; Cephalosporins; Community-Acquired Infections; Drug Resistance, Microbial; Erythromycin; Gram-Positive Bacteria; Humans; Japan; Ketolides; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Respiratory Tract Infections; Staphylococcus aureus

2000
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture].
    The Japanese journal of antibiotics, 2000, Volume: 53, Issue:12

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefixime; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Japan; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillin G; Penicillins; Streptococcus pneumoniae; Thienamycins

2000
[Antibacterial activity of gatifloxacin against various fresh clinical isolates in 2002].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Cefdinir; Cephalosporins; Ciprofloxacin; Dosage Forms; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Levofloxacin; Macrolides; Ofloxacin; Otorhinolaryngologic Diseases; Respiratory Tract Infections; Staphylococcus aureus; Streptococcus pneumoniae; Time Factors; Urinary Tract Infections

2002
[Susceptibility of major pathogens of acute pharyngitis and tonsillitis to levofloxacin and other oral antimicrobial drugs].
    The Japanese journal of antibiotics, 2003, Volume: 56, Issue:3

    Topics: Acute Disease; Ampicillin; Anti-Infective Agents; Azithromycin; Cefdinir; Cefpodoxime; Ceftizoxime; Cephalosporins; Clarithromycin; Enterobacteriaceae; Haemophilus influenzae; Humans; Levofloxacin; Ofloxacin; Penicillin G; Pharyngitis; Streptococcus pneumoniae; Streptococcus pyogenes; Tonsillitis

2003
Use of oral third generation cephalosporins and quinolones and occurrence of antibiotic-resistant strains in the neurogenic bladder (NB) outpatient setting: a retrospective chart audit.
    Spinal cord, 2020, Volume: 58, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antimicrobial Stewardship; Cefdinir; Cephalosporins; Drug Prescriptions; Drug Resistance, Bacterial; Female; Hospitals, Rehabilitation; Humans; Japan; Levofloxacin; Male; Middle Aged; Outpatients; Quinolones; Retrospective Studies; Spinal Cord Injuries; Urinary Bladder, Neurogenic; Young Adult

2020
Assessment of nationally recommended antibiotics for treatment of UTI in U.S.-Mexico border emergency departments.
    The American journal of emergency medicine, 2022, Volume: 61

    Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefdinir; Cefuroxime; Cephalexin; Ciprofloxacin; Emergency Service, Hospital; Fluoroquinolones; Humans; Levofloxacin; Mexico; Nitrofurantoin; Retrospective Studies; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination; United States; Urinary Tract Infections

2022