Compounds > levofloxacin
Page last updated: 2024-09-04

levofloxacin and benzbromarone

levofloxacin has been researched along with benzbromarone in 7 studies

Compound Research Comparison

Studies
(levofloxacin)		Trials
(levofloxacin)		Recent Studies (post-2010)
(levofloxacin)		Studies
(benzbromarone)		Trials
(benzbromarone)		Recent Studies (post-2010) (benzbromarone)
4,3465812,20948259208

Protein Interaction Comparison

ProteinTaxonomylevofloxacin (IC50)benzbromarone (IC50)
envelope glycoproteinHuman immunodeficiency virus 112.8
nuclear receptor corepressor 2 isoform 2Homo sapiens (human)4.811
peroxisome proliferator-activated receptor gamma isoform 2Homo sapiens (human)4.811
Adenosine receptor A3Homo sapiens (human)5.222
60 kDa heat shock protein, mitochondrialHomo sapiens (human)9.1
Cytochrome P450 2C9 Homo sapiens (human)1.0895
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.222
Mitogen-activated protein kinase 1Homo sapiens (human)1.946
Multidrug resistance-associated protein 1 Homo sapiens (human)4
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.804
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.222
Cytochrome P450 2J2Homo sapiens (human)4.26
10 kDa heat shock protein, mitochondrialHomo sapiens (human)9.1
Aldo-keto reductase family 1 member C1Homo sapiens (human)0.048
Mitogen-activated protein kinase 14Homo sapiens (human)1.235
Solute carrier family 22 member 6Homo sapiens (human)4.6
Monocarboxylate transporter 2Rattus norvegicus (Norway rat)9
Solute carrier family 22 member 12Homo sapiens (human)0.8695
Eyes absent homolog 3Homo sapiens (human)8.3
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.2
M17 leucyl aminopeptidasePlasmodium falciparum 3D781.89
M1-family alanyl aminopeptidasePlasmodium falciparum 3D762.78

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for levofloxacin and benzbromarone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for levofloxacin and benzbromarone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013