levofloxacin has been researched along with bedaquiline in 8 studies
| Studies (levofloxacin) | Trials (levofloxacin) | Recent Studies (post-2010) (levofloxacin) | Studies (bedaquiline) | Trials (bedaquiline) | Recent Studies (post-2010) (bedaquiline) |
|---|---|---|---|---|---|
| 4,346 | 581 | 2,209 | 704 | 41 | 630 |
| Protein | Taxonomy | levofloxacin (IC50) | bedaquiline (IC50) |
|---|---|---|---|
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 4.36 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 1.6 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.2486 | |
| ATP synthase subunit c | Mycolicibacterium smegmatis | 0.0119 | |
| Sigma intracellular receptor 2 | Rattus norvegicus (Norway rat) | 1.6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Kalra, S; Khatik, GL; Kumar, GN; Kumar, R; Narang, R; Nayak, SK; Singh, SK; Sudhakar, K | 1 |
| Jeong, BH; Koh, WJ; Kwon, YS | 1 |
| Boulle, A; Fox, T; Khomo, N; Kock, Y; Leslie, J; Manning, K; Meintjes, G; Mudaly, V; Stewart, A; Tiffin, N; Wasserman, S; Zhao, Y | 1 |
| Ahmad, N; Ahuja, SD; Akkerman, OW; Alffenaar, JC; Anderson, LF; Baghaei, P; Bang, D; Barry, PM; Bastos, ML; Behera, D; Benedetti, A; Bisson, GP; Boeree, MJ; Bonnet, M; Brode, SK; Brust, JCM; Cai, Y; Caumes, E; Cegielski, JP; Centis, R; Chan, ED; Chan, PC; Chang, KC; Charles, M; Cirule, A; D'Ambrosio, L; Dalcolmo, MP; de Vries, G; Dheda, K; Esmail, A; Flood, J; Fox, GJ; Fréchet-Jachym, M; Fregona, G; Gayoso, R; Gegia, M; Gler, MT; Gu, S; Guglielmetti, L; Holtz, TH; Hughes, J; Isaakidis, P; Jarlsberg, L; Kempker, RR; Keshavjee, S; Khan, FA; Kipiani, M; Koenig, SP; Koh, WJ; Kritski, A; Kuksa, L; Kvasnovsky, CL; Kwak, N; Lan, Z; Lange, C; Laniado-Laborín, R; Lee, M; Leimane, V; Leung, CC; Leung, EC; Li, PZ; Lowenthal, P; Maciel, EL; Marks, SM; Mase, S; Mbuagbaw, L; Menzies, D; Migliori, GB; Milanov, V; Miller, AC; Mitnick, CD; Modongo, C; Mohr, E; Monedero, I; Nahid, P; Ndjeka, N; O'Donnell, MR; Padayatchi, N; Palmero, D; Pape, JW; Podewils, LJ; Reynolds, I; Riekstina, V; Robert, J; Rodriguez, M; Schnippel, K; Seaworth, B; Seung, KJ; Shim, TS; Singla, R; Smith, SE; Sotgiu, G; Sukhbaatar, G; Tabarsi, P; Tiberi, S; Trajman, A; Trieu, L; Udwadia, ZF; van der Werf, TS; Veziris, N; Viiklepp, P; Vilbrun, SC; Walsh, K; Westenhouse, J; Yew, WW; Yim, JJ; Zetola, NM; Zignol, M | 1 |
| Bantubani, N; Chotoo, S; Conradie, F; Enwerem, M; Ferreira, H; Hughes, J; Ismail, N; Maartens, G; Master, I; Meintjes, G; Mohr, E; Ndjeka, N; Padanilam, X; Romero, R; Schnippel, K; Singh, N; Te Riele, J; Variava, E | 1 |
| Erber, J; Rothe, K; Schmid, RM; Schneider, J; Spinner, CD; Tschaikowsky, T; Weidlich, S | 1 |
| Gao, J; Gao, M; Li, L; Liu, F; Liu, Y; Pang, Y; Shu, W; Sun, Y; Xie, L; Zhang, L | 1 |
| An, Q; Lin, R; Wang, C; Wang, D; Yang, Q | 1 |
4 review(s) available for levofloxacin and bedaquiline
| Article | Year |
|---|---|
Recent advancements in mechanistic studies and structure activity relationship of F
Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Proton-Translocating ATPases; Structure-Activity Relationship | 2019 |
Tuberculosis: clinical trials and new drug regimens.
Topics: Acetamides; Adamantane; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Administration Schedule; Drug Design; Ethylenediamines; Female; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Oxazolidinones; Spiro Compounds; Thiazines; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2014 |
Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Carbapenems; Clofazimine; Diarylquinolines; Drug Therapy, Combination; Fluoroquinolones; Humans; Kanamycin; Levofloxacin; Linezolid; Moxifloxacin; Recurrence; Treatment Failure; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary | 2018 |
Evaluation of genetic mutations associated with phenotypic resistance to fluoroquinolones, bedaquiline, and linezolid in clinical Mycobacterium tuberculosis: A systematic review and meta-analysis.
Topics: Antitubercular Agents; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Mycobacterium tuberculosis; Phenotype; Tuberculosis, Multidrug-Resistant | 2023 |
4 other study(ies) available for levofloxacin and bedaquiline
| Article | Year |
|---|---|
Improved Treatment Outcomes With Bedaquiline When Substituted for Second-line Injectable Agents in Multidrug-resistant Tuberculosis: A Retrospective Cohort Study.
Topics: Adult; Antitubercular Agents; Coinfection; Diarylquinolines; Drug Resistance, Multiple, Bacterial; Ethambutol; Ethionamide; Female; HIV; HIV Infections; Humans; Isoniazid; Isoxazoles; Levofloxacin; Male; Mycobacterium tuberculosis; Oxazolidinones; Pyrazinamide; Retrospective Studies; South Africa; Survival Analysis; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2019 |
High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen.
Topics: Adult; Anti-HIV Agents; Antitubercular Agents; Clofazimine; Diarylquinolines; Drug Resistance, Bacterial; Drug Therapy, Combination; Extensively Drug-Resistant Tuberculosis; Female; Fluoroquinolones; HIV Infections; Humans; Levofloxacin; Linezolid; Male; Middle Aged; Poisson Distribution; South Africa; Treatment Outcome; Tuberculosis, Multidrug-Resistant | 2018 |
Successful bedaquiline-containing antimycobacterial treatment in post-traumatic skin and soft-tissue infection by Mycobacterium fortuitum complex: a case report.
Topics: Amikacin; Antitubercular Agents; Diarylquinolines; Drug Resistance, Bacterial; Female; Humans; Imipenem; Levofloxacin; Macrolides; Mycobacterium fortuitum; Mycobacterium Infections, Nontuberculous; Skin; Skin Diseases, Bacterial; Soft Tissue Infections; Soft Tissue Injuries; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Vietnam; Young Adult | 2020 |
Development and Validation of a Nomogram for Prediction of QT Interval Prolongation in Patients Administered Bedaquiline-Containing Regimens in China: a Modeling Study.
Topics: Antitubercular Agents; Clofazimine; Creatinine; Diarylquinolines; Humans; Levofloxacin; Long QT Syndrome; Moxifloxacin; Nomograms; Tuberculosis, Multidrug-Resistant | 2022 |