Page last updated: 2024-09-04

levofloxacin and antofloxacin

levofloxacin has been researched along with antofloxacin in 10 studies

Compound Research Comparison

Studies
(levofloxacin)
Trials
(levofloxacin)
Recent Studies (post-2010)
(levofloxacin)
Studies
(antofloxacin)
Trials
(antofloxacin)
Recent Studies (post-2010) (antofloxacin)
4,3465812,209261314

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Kang, Z; Li, T; Liu, Y; Lu, Y; Xiao, Y; Zhang, M1
Qi, HM; Wei, MJ; Zhang, L; Zhao, CY1
Liao, J; Liu, XD; Wang, GJ; Xie, L; Zhu, Q1
Guo, J; Han, SN; Hu, ZS; Liu, JX; Shi, J; Zhang, LR; Zhang, XM; Zhang, Z; Zhao, ZZ1
Bai, C; Huang, W; Mei, C; Wang, J; Xiao, Y; Xiu, Q; Xu, N; Zheng, Q1
Kang, ZS; Li, TY; Liu, Y; Lü, Y; Xiao, YH; Zhang, M; Zhu, Y1
Chen, P; Cui, H; Huang, WX; Jia, ZP; Li, DT; Mao, GG; Wen, AD; Xiao, YH; Xiu, QY; Xue, F; Yang, GP1
Guo, P; Ji, T; Jiang, X; Lin, Z; Liu, Y; Wang, W; Xu, Y; Zhang, P; Zhao, J1
Chen, S; Dong, L; Huang, H; Köser, CU; Moradigaravand, D; Parkhill, J; Peacock, SJ; Schön, T; Shang, Y; Wang, G; Wei, G; Yu, X1
He, XJ; Jiang, CS; Li, DZ; Liu, G; Wang, W; Zeng, XP1

Trials

5 trial(s) available for levofloxacin and antofloxacin

ArticleYear
Pharmacokinetics of antofloxacin hydrochloride, a new fluoroquinolone antibiotic, after single oral dose administration in Chinese healthy male volunteers.
    Biopharmaceutics & drug disposition, 2008, Volume: 29, Issue:3

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Asian People; China; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Half-Life; Humans; Levofloxacin; Male; Ofloxacin; Tissue Distribution

2008
A phase II study of antofloxacin hydrochloride, a novel fluoroquinolone, for the treatment of acute bacterial infections.
    Chemotherapy, 2010, Volume: 56, Issue:5

    Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Bronchitis, Chronic; Demography; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Pyelonephritis

2010
Pharmacokinetic study of single and multiple oral dose administration of antofloxacin hydrochloride in healthy male volunteers.
    Chinese medical journal, 2011, Volume: 124, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Humans; Levofloxacin; Male; Ofloxacin; Young Adult

2011
[A multi-center, randomized, controlled, double blind and double dummy clinical trial of antofloxacin hydrochloride tablet versus levofloxacin tablet for the treatment of acute bacterial infections].
    Zhonghua nei ke za zhi, 2011, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Double-Blind Method; Female; Humans; Levofloxacin; Male; Middle Aged; Ofloxacin; Young Adult

2011
Efficacy and Safety of Antofloxacin-Based Triple Therapy for Helicobacter pylori Eradication Failure in China.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:1

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; China; Drug Therapy, Combination; Esomeprazole; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Ofloxacin; Proton Pump Inhibitors; Treatment Outcome

2022

Other Studies

5 other study(ies) available for levofloxacin and antofloxacin

ArticleYear
Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes.
    Acta pharmacologica Sinica, 2008, Volume: 29, Issue:12

    Topics: Animals; Anti-Infective Agents; Aryl Hydrocarbon Hydroxylases; Aza Compounds; Ciprofloxacin; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C9; Fluoroquinolones; Gatifloxacin; Humans; Isoenzymes; Levofloxacin; Microsomes, Liver; Molecular Structure; Moxifloxacin; Ofloxacin; Quinolines; Reproducibility of Results

2008
Mechanism-based inhibition of CYP1A2 by antofloxacin, an 8-NH2 derivative of levofloxacin in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Kinetics; Levofloxacin; Male; Microsomes, Liver; Models, Biological; Ofloxacin; Phenacetin; Rats; Rats, Sprague-Dawley

2009
The action of a novel fluoroquinolone antibiotic agent antofloxacin hydrochloride on human-ether-à-go-go-related gene potassium channel.
    Basic & clinical pharmacology & toxicology, 2010, Volume: 107, Issue:2

    Topics: Anti-Bacterial Agents; Cell Line; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Gene Expression Regulation; Humans; Kidney; Levofloxacin; Ofloxacin; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Transport; Structure-Activity Relationship; Transfection

2010
Effect of C-5 position on the photochemical properties and phototoxicity of antofloxacin and levofloxacin: A stable and transient study.
    Journal of photochemistry and photobiology. B, Biology, 2016, Volume: 155

    Topics: Electron Transport; Electrophoresis, Polyacrylamide Gel; Energy Transfer; Fluoroquinolones; Lasers, Solid-State; Levofloxacin; Ofloxacin; Photolysis; Quantum Theory

2016
Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and Moxifloxacin.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9

    Topics: Antitubercular Agents; China; DNA Gyrase; Drug Dosage Calculations; Drug Resistance, Bacterial; Fluoroquinolones; Gene Expression; Genotype; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Ofloxacin; Tuberculosis, Pulmonary

2016