Page last updated: 2024-08-22

levodopa methyl ester and carbidopa

levodopa methyl ester has been researched along with carbidopa in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's6 (54.55)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Borisenko, SA; Männistö, PT; Törnwall, M; Tuomainen, P; Tuominen, RK1
Bramante, L; Quinn, NP; Ruggieri, S; Steiger, MJ; Stocchi, F1
Carey, RJ1
Goshima, Y; Misu, Y; Nakamura, S1
Meadows, GG; Pierson, HF1
Abdallah, RM; Desai, PR; Meadows, GG; Pierson, HF1
Jenner, P; Marsden, CD; Rose, S1
Eller, RV; Gash, DM; Greenamyre, JT; Kurlan, R; Ovadia, A; Zhang, Z1
Acerbi, D; Bettini, R; Caponetti, G; Catellani, PL; Cocconi, D; Colombo, P; Magi, N; Musa, R; Santi, P; Ventura, P1
Dall'Armi, V; Kulisevsky, J; Lamberti, P; Obeso, JA; Stocchi, F; Zappia, M1
Capelli, C; Charlier, B; Cilia, R; Coglianese, A; Conti, V; D'Urso, A; de Grazia, U; Eleopra, R; Izzo, V; Molteni, L1

Trials

2 trial(s) available for levodopa methyl ester and carbidopa

ArticleYear
Influence of layer position on in vitro and in vivo release of levodopa methyl ester and carbidopa from three-layer matrix tablets.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2002, Volume: 53, Issue:2

    Topics: Administration, Oral; Antiparkinson Agents; Biological Availability; Carbidopa; Chemistry, Pharmaceutical; Cross-Over Studies; Drug Delivery Systems; Humans; Levodopa; Pilot Projects; Tablets, Enteric-Coated

2002
Melevodopa/carbidopa effervescent formulation in the treatment of motor fluctuations in advanced Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2010, Sep-15, Volume: 25, Issue:12

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antiparkinson Agents; Carbidopa; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Humans; Intention to Treat Analysis; Levodopa; Male; Middle Aged; Parkinson Disease; Treatment Outcome

2010

Other Studies

9 other study(ies) available for levodopa methyl ester and carbidopa

ArticleYear
Effect of nitecapone and clorgyline, given intracerebro-ventricularly on L-dopa metabolism in the rat brain.
    Neuroreport, 1992, Volume: 3, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carbidopa; Catechols; Cerebral Ventricles; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Hypothalamus; Injections, Intraventricular; Levodopa; Male; Pentanones; Prolactin; Rats; Rats, Wistar; Thyrotropin

1992
The clinical efficacy of single morning doses of levodopa methyl ester: dispersible Madopar and Sinemet plus in Parkinson disease.
    Clinical neuropharmacology, 1992, Volume: 15, Issue:6

    Topics: Benserazide; Carbidopa; Drug Combinations; Humans; Levodopa; Middle Aged; Parkinson Disease

1992
Chronic L-dopa treatment in the unilateral 6-OHDA rat: evidence for behavioral sensitization and biochemical tolerance.
    Brain research, 1991, Dec-24, Volume: 568, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Carbidopa; Corpus Striatum; Denervation; Drug Tolerance; Functional Laterality; Homovanillic Acid; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1991
L-dihydroxyphenylalanine methyl ester is a potent competitive antagonist of the L-dihydroxyphenylalanine-induced facilitation of the evoked release of endogenous norepinephrine from rat hypothalamic slices.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:2

    Topics: Animals; Binding, Competitive; Carbidopa; Cocaine; Hydrazines; Hypothalamus; In Vitro Techniques; Levodopa; Norepinephrine; Propranolol; Rats; Structure-Activity Relationship; Sulpiride

1991
Sodium ascorbate enhancement of carbidopa-levodopa methyl ester antitumor activity against pigmented B16 melanoma.
    Cancer research, 1983, Volume: 43, Issue:5

    Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Carbidopa; Cell Line; Diet; Drug Synergism; Drug Therapy, Combination; Female; Injections, Intraperitoneal; Levodopa; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Tyrosine

1983
Dietary influence of tyrosine and phenylalanine on the response of B16 melanoma to carbidopa-levodopa methyl ester chemotherapy.
    Cancer research, 1982, Volume: 42, Issue:8

    Topics: Animals; Carbidopa; Diet; Drug Evaluation, Preclinical; Female; Levodopa; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Tyrosine

1982
Chronic administration does not alter the accumulation of L-dopa into muscle.
    Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Carbidopa; Dopamine; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Long-Term Care; Male; Metabolic Clearance Rate; Muscles; Rats; Rats, Wistar

1994
Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease.
    Annals of neurology, 1994, Volume: 35, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetamides; Analysis of Variance; Animals; Anticonvulsants; Antiparkinson Agents; Brain; Carbidopa; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Levodopa; Macaca mulatta; Male; Motor Activity; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors

1994
Development and Validation of a New LC-MS/MS Bioanalytical Method for the Simultaneous Determination of Levodopa, Levodopa Methyl Ester, and Carbidopa in Human Plasma Samples.
    Molecules (Basel, Switzerland), 2023, May-23, Volume: 28, Issue:11

    Topics: Carbidopa; Chromatography, Liquid; Humans; Levodopa; Male; Middle Aged; Reproducibility of Results; Tandem Mass Spectrometry

2023