Page last updated: 2024-08-17

levodopa and tozadenant

levodopa has been researched along with tozadenant in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Gaba, S; Gupta, GD; Monga, V; Patel, R; Saini, A; Singh, G1
Bandak, S; Docu-Axelerad, A; Hauser, RA; Kenney, C; Kieburtz, KD; Kozyolkin, O; Lew, M; Meya, U; Neale, A; Olanow, CW; Pourcher, E; Resburg, C1
Downey, P; Michel, A; Nicolas, JM; Scheller, D1
De Wolf, C; Downey, P; Michel, A; Scheller, D; Schwarting, R; Van Damme, X1
Aradi, SD; Hauser, RA; LeWitt, PA; Rascol, O1

Reviews

1 review(s) available for levodopa and tozadenant

ArticleYear
Adenosine receptor antagonists: Recent advances and therapeutic perspective.
    European journal of medicinal chemistry, 2022, Jan-05, Volume: 227

    Topics: Dose-Response Relationship, Drug; Humans; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Structure-Activity Relationship

2022

Trials

1 trial(s) available for levodopa and tozadenant

ArticleYear
Tozadenant (SYN115) in patients with Parkinson's disease who have motor fluctuations on levodopa: a phase 2b, double-blind, randomised trial.
    The Lancet. Neurology, 2014, Volume: 13, Issue:8

    Topics: Adenosine A2 Receptor Antagonists; Aged; Antiparkinson Agents; Benzothiazoles; Cross-Over Studies; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Internationality; Levodopa; Male; Middle Aged; Parkinson Disease

2014

Other Studies

3 other study(ies) available for levodopa and tozadenant

ArticleYear
Unprecedented therapeutic potential with a combination of A2A/NR2B receptor antagonists as observed in the 6-OHDA lesioned rat model of Parkinson's disease.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Benzothiazoles; Drug Therapy, Combination; Levodopa; Mass Spectrometry; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Purines; Pyrimidines; Rats; Receptors, N-Methyl-D-Aspartate; Triazoles

2014
Behavioural Assessment of the A2a/NR2B Combination in the Unilateral 6-OHDA-Lesioned Rat Model: A New Method to Examine the Therapeutic Potential of Non-Dopaminergic Drugs.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adenosine A2 Receptor Antagonists; Animals; Benserazide; Benzothiazoles; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Combinations; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Receptors, N-Methyl-D-Aspartate

2015
The challenge of developing adenosine A
    Parkinsonism & related disorders, 2020, Volume: 80 Suppl 1

    Topics: Adenosine; Animals; Antiparkinson Agents; Benzothiazoles; Humans; Levodopa; Parkinson Disease; Purines

2020