levodopa has been researched along with sk&f-38393 in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (14.06) | 18.7374 |
| 1990's | 39 (60.94) | 18.2507 |
| 2000's | 10 (15.63) | 29.6817 |
| 2010's | 6 (9.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Close, SP; Elliott, PJ; Walsh, DM | 1 |
| Breese, GR; Criswell, HE; Duncan, GE; Johnson, KB; Jurevics, HA; Mueller, RA; Napier, TC; Simson, PE | 1 |
| Di Chiara, G; Fenu, S; Morelli, M | 1 |
| Collier, TJ; Sladek, JR; Steece-Collier, K; Yurek, DM | 1 |
| Britton, DR; Curzon, P; Kebabian, JW | 1 |
| Barthelmebs, M; Froehly, S; Grima, M; Imbs, JL; Stephan, D; Vailly, B; Velly, J | 1 |
| Joyce, JN; Neal, BS | 1 |
| Breese, GR; Criswell, HE; Iorio, LC; McQuade, RD; Mueller, RA | 1 |
| Bédard, PJ; Di Paolo, T; Gagnon, C | 1 |
| Di Chiara, G; Morelli, M | 1 |
| Chase, TN; Engber, TM; Kuo, S; Susel, Z | 1 |
| Casagrande, C; La Regina, A; Merlo, L | 1 |
| Chase, TN; Engber, TM; Susel, Z; Walters, JR; Weick, BG | 1 |
| Boyce, S; Iversen, SD; Rupniak, NM; Steventon, MJ | 1 |
| Bédard, PJ; Di Paolo, T; Rouillard, C | 1 |
| Hasenfuss, G; Just, H | 1 |
| Chase, TN; Engber, TM; Juncos, JL; Susel, Z | 1 |
| Beart, PM; Cook, CJ; Hashizume, M; Jackson, DM; Tabar, J | 1 |
| Barone, P; Braun, A; Chase, TN; Fabbrini, G; Mouradian, MM; Serrati, C | 1 |
| Heikkila, RE; Manzino, L; Sonsalla, PK | 1 |
| Jenner, P; Marsden, CD | 1 |
| Close, SP; Marriott, AS; Pay, S | 1 |
| Baumeister, A; Breese, GR; Frye, GD; Mueller, RA; Napier, TC | 1 |
| McDevitt, JT; Setler, PE | 1 |
| Kaur, S; Starr, MS | 1 |
| Boldry, RC; Chase, TN; Engber, TM; Papa, SM | 1 |
| Bentlage, C; Björklund, A; Nikkhah, G; Olsson, M | 1 |
| Barone, P; Campanella, G; Cicarelli, G; Di Chiara, G; Morelli, M; Popoli, M | 1 |
| Kaur, S; Starr, BS; Starr, MS | 1 |
| Dawson, R; Felheim, R; Phillips, MI | 1 |
| Boldry, RC; Chase, TN; Engber, TM | 1 |
| Di Chiara, G; Fenu, S; Morelli, M; Pinna, A | 1 |
| Cole, DG; Hyman, SE; Kobierski, LA; Konradi, C | 1 |
| Boldry, RC; Chase, TN; Kask, AM; Papa, SM | 1 |
| Akiyama, K; Ishihara, T; Kashihara, K; Shiro, Y; Shohmori, T | 1 |
| Biggs, C; Fowler, L; Starr, M; Whitton, P | 1 |
| Kaur, S; Starr, M | 1 |
| Brooks, S; Kaur, S; Starr, BS; Starr, MS | 1 |
| Ibata, Y; Murakami, T; Nakamura, T; Okamura, H; Yokoyama, C | 1 |
| Imahori, Y; Inokuchi, K; Kusuki, T; Ueda, S | 1 |
| Andringa, G; Cools, AR; Drukarch, B; Stoof, JC; Vermeulen, RJ | 1 |
| Barlas, C; Chugh, A; Johnson, RL; Marcotte, ER; Mishra, RK; Whan, D | 1 |
| Barone, P; DiChiara, G; Morelli, M; Pellecchia, MT; Vallone, D; Verde, P | 1 |
| Berndt, TJ; Knox, FG; LeClaire, MM | 1 |
| Drukarch, B; Stoof, JC; van de Witte, SV; Voorn, P | 1 |
| Chase, TN; Oh, JD; Vaughan, CL | 1 |
| Consolo, S; Di Chiara, G; Giorgi, S; Morelli, M; Rimoldi, M | 1 |
| Lalonde, R; Lestienne, F; Thullier, F | 1 |
| Carta, A; Fenu, S; Morelli, M | 1 |
| Groenewegen, HJ; Van De Witte, SV; Voorn, P | 1 |
| Hillman, R; Parvez, F; Pendleton, RG; Sayed, M | 1 |
| Aubert, I; Barthe, N; Bezard, E; Bioulac, BH; Bloch, B; Dovero, S; Fisone, G; Gross, CE; Guigoni, C; Håkansson, K; Li, Q | 1 |
| Cauli, O; Morelli, M; Pinna, A | 1 |
| Bae, E; Bang, S; Chun, B; Chung, J; Kang, J; Kim, J; Lee, S; Lee, Y; Paik, D | 1 |
| Chen, J; Ma, L; Wang, F; Zhang, H; Zhen, X | 1 |
| Ballion, B; Chetrit, J; Frenois, F; Gonon, F; Murer, MG; Zold, CL | 1 |
| Cenci, MA; Lindgren, HS; Ohlin, KE | 1 |
| Caramés, JM; Moratalla, R; Murer, MG; Solís, JM; Solís, O; Suárez, LM; Taravini, IR | 1 |
| Bimpisidis, Z; Cenci, MA; Iderberg, H; Rylander, D | 1 |
| Barraud, Q; Bezard, E; Ghorayeb, I; Hyacinthe, C; Tison, F | 1 |
| Canela, EI; Canet-Pons, J; Casadó, V; Cortés, A; Dopeso-Reyes, IG; Farré, D; Franco, R; Labandeira-García, JL; Lanciego, JL; Lluís, C; Mallol, J; Moreno, E; Muñoz, A; Navarro, G; Reyes-Resina, I; Rico, AJ | 1 |
| Lin, JY; Liu, ZG; Wang, MH; Wang, XJ; Xie, CL; Zhang, SF; Zhang, Y | 1 |
| Arcuri, L; Brambilla, R; Fasano, S; Frassineti, M; Journigan, BV; Mercatelli, D; Meyer, ME; Morari, M; Morella, I; Novello, S; Pisanò, CA; Polgar, WE; Zaveri, NT | 1 |
3 review(s) available for levodopa and sk&f-38393
| Article | Year |
|---|---|
Development of dopaminergic drugs for the chronic treatment of congestive heart failure.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Deoxyepinephrine; Dopamine; Dopamine Agents; Fenoldopam; Heart Failure; Humans; Levodopa; Receptors, Dopamine | 1990 |
Clinical relevance of long-term therapy with levodopa and orally active dopamine analogues in patients with chronic congestive heart failure.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Administration, Oral; Chronic Disease; Deoxyepinephrine; Dopamine Agents; Fenoldopam; Heart Failure; Humans; Levodopa; Vasodilator Agents | 1989 |
The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Callithrix; Corpus Striatum; Disease Models, Animal; Dopamine; Ergolines; Humans; Levodopa; Macaca mulatta; Neural Pathways; Pargyline; Parkinson Disease; Parkinson Disease, Secondary; Pyridines; Quinpirole; Rats; Saimiri; Selegiline; Species Specificity; Substantia Nigra | 1986 |
1 trial(s) available for levodopa and sk&f-38393
| Article | Year |
|---|---|
Selective D-1 dopamine receptor agonist treatment of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aged; Benzazepines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Movement; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D1 | 1987 |
60 other study(ies) available for levodopa and sk&f-38393
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Dopamine D1 and D2 receptor interactions in the MPTP-treated marmoset.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Callithrix; Dopamine Agents; Ergolines; Female; Levodopa; Male; Movement; Parkinson Disease, Secondary; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1992 |
Augmented sensitivity of D1-dopamine receptors in lateral but not medial striatum after 6-hydroxydopamine-induced lesions in the neonatal rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Animals, Newborn; Autoradiography; Corpus Striatum; Female; Guanosine Triphosphate; Levodopa; Nucleus Accumbens; Oxidopamine; Pregnancy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Tyrosine 3-Monooxygenase | 1992 |
Blockade of N-methyl-D-aspartate receptors potentiates dopaminergic responses in the 6-OHDA model of Parkinson: differential role of D-1 and D-2 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Caudate Nucleus; Dizocilpine Maleate; Dopamine; Drug Synergism; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 1992 |
Chronic levodopa impairs the recovery of dopamine agonist-induced rotational behavior following neural grafting.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Brain Tissue Transplantation; Dopamine; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Fetal Tissue Transplantation; Levodopa; Male; Mesencephalon; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 1991 |
Rapid reversal of denervation supersensitivity of dopamine D1 receptors by l-dopa or a novel dopamine D1 receptor agonist, A68930.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Chromans; Denervation; Dopamine Agents; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1 | 1991 |
Effects of dopamine prodrugs and fenoldopam on glomerular hyperfiltration in streptozotocin-induced diabetes in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Carbidopa; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dopamine Agents; Fenoldopam; Glomerular Filtration Rate; Hemodynamics; Levodopa; Male; Prodrugs; Rats; Rats, Inbred Strains; Streptozocin | 1991 |
Dopamine D1 receptor behavioral responsitivity following selective lesions of the striatal patch compartment during development.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Autoradiography; Corpus Striatum; Haloperidol; Hydroxydopamines; Levodopa; Mazindol; Motor Activity; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior; Tritium | 1991 |
Pharmacological evaluation of SCH-12679: evidence for an in vivo antagonism of D1-dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aggression; Animals; Antipsychotic Agents; Avoidance Learning; Benzazepines; Dopamine Antagonists; Female; Hydroxydopamines; Levodopa; Oxidopamine; Pregnancy; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides | 1990 |
Effect of chronic treatment of MPTP monkeys with dopamine D-1 and/or D-2 receptor agonists.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Autoradiography; Brain; Bromocriptine; Carbidopa; Catecholamines; Dopamine Agents; Female; Levodopa; Macaca fascicularis; Receptors, Dopamine; Spiperone | 1990 |
MK-801 potentiates dopaminergic D1 but reduces D2 responses in the 6-hydroxydopamine model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benserazide; Dizocilpine Maleate; Dopamine Agents; Ergolines; Hydroxydopamines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Stereotyped Behavior | 1990 |
Chronic levodopa treatment alters basal and dopamine agonist-stimulated cerebral glucose utilization.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Autoradiography; Basal Ganglia; Brain; Carbon Radioisotopes; Deoxyglucose; Dopamine Agents; Dose-Response Relationship, Drug; Ergolines; Glucose; Levodopa; Male; Neural Pathways; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Thalamus | 1990 |
Responses of substantia nigra pars reticulata neurons to GABA and SKF 38393 in 6-hydroxydopamine-lesioned rats are differentially affected by continuous and intermittent levodopa administration.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Electrophysiology; gamma-Aminobutyric Acid; Hydroxydopamines; Injections, Intravenous; Iontophoresis; Levodopa; Male; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Sympathectomy, Chemical | 1990 |
Differential effects of D1 and D2 agonists in MPTP-treated primates: functional implications for Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Dyskinesia, Drug-Induced; Levodopa; Male; Motor Activity; Oxazines; Parkinson Disease, Secondary; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Saimiri | 1990 |
Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Bromocriptine; Dopamine; Female; Homovanillic Acid; Kinetics; Levodopa; Macaca fascicularis; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Receptors, Dopamine; Spiperone | 1990 |
Continuous and intermittent levodopa differentially affect rotation induced by D-1 and D-2 dopamine agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine Agents; Hydroxydopamines; Levodopa; Male; Motor Activity; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
The effects on central dopamine function of chronic L-dopa (methyl ester hydrochloride) treatment of mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Body Temperature; Bromocriptine; Dextroamphetamine; Dopamine; Levodopa; Mice; Mice, Inbred Strains; Motor Activity; Receptors, Dopamine; Stereotyped Behavior | 1989 |
Interactions of D1 and D2 dopamine receptors on the ipsilateral vs. contralateral side in rats with unilateral lesions of the dopaminergic nigrostriatal pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Basal Ganglia; Benzazepines; Corpus Striatum; Denervation; Dextroamphetamine; Ergolines; Female; Flunarizine; Functional Laterality; Haloperidol; Levodopa; Neural Pathways; Parkinson Disease; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Substantia Nigra | 1988 |
Failure of SKF 38393-A to relieve parkinsonian symptoms induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the marmoset.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benserazide; Benzazepines; Callitrichinae; Levodopa; Male; Movement Disorders; Parkinson Disease, Secondary; Pyridines; Tremor | 1985 |
Evidence that D-1 dopamine receptors contribute to the supersensitive behavioral responses induced by L-dihydroxyphenylalanine in rats treated neonatally with 6-hydroxydopamine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Dihydroxyphenylalanine; Drug Interactions; Ergolines; Female; Flupenthixol; Haloperidol; Hydroxydopamines; Levodopa; Male; Motor Activity; Oxidopamine; Pregnancy; Quinpirole; Rats; Receptors, Dopamine; Self Mutilation; Stereotyped Behavior | 1985 |
Differential effects of dopamine agonists in mature and immature rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Age Factors; Animals; Animals, Newborn; Apomorphine; Benzazepines; Bromocriptine; Dextroamphetamine; Dopamine; Female; Humans; Levodopa; Male; Motor Activity; Rats; Scopolamine; Stereotyped Behavior; Sympathomimetics | 1981 |
Antiparkinsonian action of dextromethorphan in the reserpine-treated mouse.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Behavior, Animal; Dextromethorphan; Dopamine Agonists; Drug Interactions; Levodopa; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Activity; Parkinson Disease, Secondary; Phenethylamines; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine | 1995 |
NMDA receptor blockade reverses motor response alterations induced by levodopa.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Levodopa; Male; Motor Activity; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rotation; Stereotyped Behavior | 1994 |
Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphine; Brain Tissue Transplantation; Carbidopa; Dextroamphetamine; Disease Models, Animal; Dopamine; Dopamine Agonists; Ergolines; Female; Fetal Tissue Transplantation; Forelimb; Functional Laterality; Levodopa; Motor Activity; Movement Disorders; Norepinephrine; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Transplantation, Heterotopic | 1995 |
Behavioural sensitization in 6-hydroxydopamine lesioned rats involves the dopamine signal transduction: changes in DARPP-32 phosphorylation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Autoradiography; Behavior, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Levodopa; Male; Nerve Tissue Proteins; Oxidopamine; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Signal Transduction; Sympathectomy, Chemical | 1994 |
Role of D1 receptor mechanisms in the potentiation of motor responses to L-dopa and apomorphine by MK 801 in the reserpine-treated mouse.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Levodopa; Male; Mice; Motor Activity; Receptors, Dopamine; Reserpine | 1994 |
Dopamine receptor agonists and antagonists both inhibit dopamine secretion in LLC-PK1 cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benzazepines; Cell Line; Chlorpromazine; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Dopamine Antagonists; Epithelial Cells; Epithelium; Ergolines; Fenoldopam; Kidney; Levodopa; Phenothiazines; Quinpirole; Trifluoperazine | 1993 |
Influence of previous exposure to levodopa on the interaction between dizocilpine and dopamine D1 and D2 agonists in rats with 6-hydroxydopamine-induced lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Diseases; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Levodopa; Male; Motor Activity; N-Methylaspartate; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1993 |
Adenosine A2 receptors interact negatively with dopamine D1 and D2 receptors in unilaterally 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Animals; Antihypertensive Agents; Autoradiography; Basal Ganglia; Benserazide; Binding Sites; Dopamine Agents; Ergolines; Levodopa; Male; Neural Pathways; Neurons; Oxidopamine; Phenethylamines; Quinolinic Acid; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic P1; Stereotyped Behavior | 1994 |
6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dopamine; Embryo, Mammalian; Ergolines; Gene Expression; Genes, fos; Levodopa; Male; Neurons; Oxidopamine; Phosphorylation; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Substantia Nigra | 1994 |
MK-801 reverses effects of chronic levodopa on D1 and D2 dopamine agonist-induced rotational behavior.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Ergolines; Excitatory Amino Acid Antagonists; Levodopa; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympatholytics | 1995 |
Levodopoa but not bromocriptine induces AP-1 and creb DNA-binding activity in the dopamine-depleted striatum of the rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Base Sequence; Behavior, Animal; Bromocriptine; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Dopamine; Dopamine Agonists; Levodopa; Male; Molecular Sequence Data; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Transcription Factor AP-1 | 1996 |
Effects of glutamate antagonists on nigral dopamine release in the reserpine-treated rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Methyltyrosine; Animals; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Levodopa; Methyltyrosines; Raclopride; Rats; Reserpine; Salicylamides; Substantia Nigra | 1996 |
Motor effects of lamotrigine in naive and dopamine-depleted mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Uptake Inhibitors; Animals; Anticonvulsants; Antiparkinson Agents; Benserazide; Depression, Chemical; Dopamine; Dopamine Agonists; Gait; Lamotrigine; Levodopa; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenethylamines; Posture; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Triazines | 1996 |
Motor actions of eliprodil in the normal and monoamine-depleted mouse: a role in the treatment of Parkinson's disease?
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Biogenic Monoamines; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Dose-Response Relationship, Drug; Efferent Pathways; Excitatory Amino Acid Antagonists; Levodopa; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Neurons; Parkinson Disease; Phenethylamines; Piperidines; Receptors, Dopamine D1; Reserpine; Sympatholytics | 1996 |
Self-injurious behavior and dopaminergic neuron system in neonatal 6-hydroxydopamine-lesioned rat: 2. Intracerebral microinjection of dopamine agonists and antagonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; Brain; Caudate Nucleus; Dopamine Agonists; Dopamine Antagonists; Female; Functional Laterality; Levodopa; Microinjections; Neurons; Nucleus Accumbens; Oxidopamine; Pregnancy; Putamen; Rats; Rats, Wistar; Self Mutilation; Substantia Nigra | 1997 |
Dopaminergic modulation of LTP induction in the dentate gyrus of intact brain.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia, General; Animals; Benzazepines; Brain; Dentate Gyrus; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Electric Stimulation; Electrophysiology; Immunohistochemistry; Levodopa; Long-Term Potentiation; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D5 | 1997 |
Dopamine receptor subtypes as targets for the pharmacotherapy of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Benzazepines; Dopamine Agonists; Haplorhini; Levodopa; Motor Activity; Parkinson Disease, Secondary; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1 | 1998 |
Modulation of dopamine receptor agonist-induced rotational behavior in 6-OHDA-lesioned rats by a peptidomimetic analogue of Pro-Leu-Gly-NH2 (PLG).
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Brain; Dopamine; Dopamine Agonists; Drug Synergism; Levodopa; Male; MSH Release-Inhibiting Hormone; Oxidopamine; Pyrrolidinones; Quinpirole; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1997 |
Behavioural sensitization in 6-hydroxydopamine-lesioned rats is related to compositional changes of the AP-1 transcription factor: evidence for induction of FosB- and JunD-related proteins.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benserazide; Cell Nucleus; Corpus Striatum; Denervation; Dizocilpine Maleate; Gene Expression Regulation; Levodopa; Male; Motor Activity; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Transcription Factor AP-1 | 1997 |
Effect of renal interstitial infusion of L-dopa on sodium and phosphate excretions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dopamine; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Infusions, Parenteral; Kidney Tubules, Proximal; Levodopa; Male; Natriuresis; Phosphates; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Sodium; Sulpiride | 1998 |
Priming with L-DOPA differently affects dynorphin and substance P mRNA levels in the striatum of 6-hydroxydopamine-lesioned rats after challenge with dopamine D1-receptor agonist.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain; Corpus Striatum; Dynorphins; Injections, Intraperitoneal; Injections, Subcutaneous; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D1; RNA, Messenger; Stereotaxic Techniques; Substance P | 1998 |
Effect of dopamine denervation and dopamine agonist administration on serine phosphorylation of striatal NMDA receptor subunits.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antibodies; Antiparkinson Agents; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Corpus Striatum; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Levodopa; Male; Motor Neurons; Nerve Degeneration; Oxidopamine; Parkinson Disease, Secondary; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Sulfonamides; Sympatholytics | 1999 |
Increased striatal expression of glutamate decarboxylase 67 after priming of 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Functional Laterality; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Isoenzymes; Levodopa; Male; Motor Activity; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger; Time Factors; Transcription, Genetic | 1999 |
Effects of dopaminergic agents and of an NMDA receptor antagonist on motor coordination in Lurcher mutant mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Carbidopa; Dextromethorphan; Dopamine Agonists; Dopamine Antagonists; Female; Levodopa; Male; Mice; Mice, Neurologic Mutants; Olivopontocerebellar Atrophies; Psychomotor Performance; Receptors, N-Methyl-D-Aspartate | 1999 |
Alterations in GAD67, dynorphin and enkephalin mRNA in striatal output neurons following priming in the 6-OHDA model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dopamine Agonists; Down-Regulation; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Gene Expression; Glutamate Decarboxylase; Isoenzymes; Levodopa; Neostriatum; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; RNA, Messenger; Sympatholytics; Up-Regulation | 2001 |
MK-801 alters the effects of priming with L-DOPA on dopamine D1 receptor-induced changes in neuropeptide mRNA levels in the rat striatal output neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Drug Interactions; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Immunohistochemistry; Levodopa; Male; Motor Activity; Neostriatum; Neurons; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tachykinins; Tyrosine 3-Monooxygenase | 2002 |
Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Methyltyrosine; alpha-Synuclein; Animals; Animals, Genetically Modified; Antiparkinson Agents; Bromocriptine; Disease Models, Animal; Drosophila melanogaster; Genotype; Levodopa; Motor Activity; Nerve Tissue Proteins; Neurons; Parkinson Disease; Pergolide; Postural Balance; Synapses; Synucleins | 2002 |
Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Blotting, Western; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Female; Guanosine 5'-O-(3-Thiotriphosphate); Immunohistochemistry; In Situ Hybridization; Isotopes; Levodopa; Macaca fascicularis; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Nortropanes; Parkinsonian Disorders; Phosphoproteins; Radioligand Assay; Receptors, Dopamine D1; Receptors, Dopamine D2; Signal Transduction; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2005 |
Subchronic intermittent caffeine administration to unilaterally 6-hydroxydopamine-lesioned rats sensitizes turning behaviour in response to dopamine D(1) but not D(2) receptor agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics | 2005 |
Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Genetically Modified; Cell Death; Cell Proliferation; Dopamine; Dopamine Agonists; Drosophila; Drosophila Proteins; Embryo, Nonmammalian; Gene Expression Regulation; Green Fluorescent Proteins; GTP Phosphohydrolases; GTP-Binding Proteins; Levodopa; Male; Membrane Proteins; Neurons; Sequence Alignment; Tyrosine 3-Monooxygenase | 2008 |
Chronic SKF83959 induced less severe dyskinesia and attenuated L-DOPA-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Dyskinesia, Drug-Induced; Levodopa; Male; Movement; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spiperone; Sympatholytics; Time Factors | 2007 |
D2 receptor stimulation, but not D1, restores striatal equilibrium in a rat model of Parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2009 |
Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aminoacetonitrile; Animals; Antiparkinson Agents; Basal Ganglia; Benzazepines; Bromocriptine; Disease Models, Animal; Dopamine Agents; Dopamine D2 Receptor Antagonists; Extracellular Signal-Regulated MAP Kinases; Female; Levodopa; Neovascularization, Pathologic; Oxidopamine; Parkinsonian Disorders; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides | 2009 |
L-DOPA treatment selectively restores spine density in dopamine receptor D2-expressing projection neurons in dyskinetic mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Cerebral Cortex; Corpus Striatum; Dendritic Spines; Dopamine Agonists; Dyskinesia, Drug-Induced; Levodopa; Male; Membrane Potentials; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Oxidopamine; Parkinsonian Disorders; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2014 |
Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: effects of combined treatment and possible mechanisms of action.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiparkinson Agents; Dopamine Agonists; Drug Synergism; Dyskinesia, Drug-Induced; Levodopa; Parkinsonian Disorders; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Receptors, Dopamine D1; Serotonin Receptor Agonists; Thiazoles | 2013 |
D1 receptor agonist improves sleep-wake parameters in experimental parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Electrocardiography; Electroencephalography; Electromyography; Female; Levodopa; Macaca fascicularis; Macaca mulatta; Parkinsonian Disorders; Quinpirole; Sleep; Sleep Disorders, Circadian Rhythm; Telemetry; Time Factors; Wakefulness | 2014 |
Stronger Dopamine D1 Receptor-Mediated Neurotransmission in Dyskinesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Caudate Nucleus; Corpus Striatum; Dimerization; Dominance, Cerebral; Dopamine; Dopamine Agonists; Dyskinesia, Drug-Induced; Gene Expression Regulation; Levodopa; Macaca fascicularis; Male; Oxidopamine; Parkinsonian Disorders; Putamen; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D3 | 2015 |
Inhibition of Glycogen Synthase Kinase-3β (GSK-3β) as potent therapeutic strategy to ameliorates L-dopa-induced dyskinesia in 6-OHDA parkinsonian rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cyclic AMP-Dependent Protein Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Dyskinesia, Drug-Induced; Glycogen Synthase Kinase 3 beta; Levodopa; Mitogen-Activated Protein Kinase 3; Oxidopamine; Parkinsonian Disorders; Phosphorylation; Rats; Receptors, Dopamine D1; tau Proteins; Thiadiazoles; Tyrosine 3-Monooxygenase | 2016 |
Anti-Parkinsonian and anti-dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetamides; Animals; Antiparkinson Agents; Corpus Striatum; Cricetinae; Dyskinesia, Drug-Induced; Extracellular Signal-Regulated MAP Kinases; Levodopa; Male; Nociceptin Receptor; Oxidopamine; Phosphorylation; Piperidines; Radioligand Assay; Rats; Receptors, Opioid | 2018 |