levodopa and serine
levodopa has been researched along with serine in 28 studies
Research
Studies (28)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (57.14) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 5 (17.86) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Falck, B; Hardebo, JE; Owman, C | 1 |
| Gabreëls, FJ; Joosten, EM; Keyser, A; Korten, JJ | 1 |
| Kagamihara, Y; Nagaoka, M; Nakajima, Y; Tanaka, R | 1 |
| Nagatsu, T | 1 |
| Narabayashi, H | 1 |
| Kondo, T; Nagatsu, T; Narabayashi, H; Yokochi, F | 1 |
| Karai, N; Kato, T; Katsube, J; Katsuyama, M; Nakamura, M | 1 |
| Imai, H; Komiya, T; Narabayashi, H; Usui, S | 1 |
| Reches, A | 1 |
| Fahn, S; Jackson-Lewis, V; Reches, A | 1 |
| Ogawa, N; Takayama, H; Yamamoto, M | 1 |
| Fawcett, CP; Krulich, L; McCann, SM; Ojeda, SR | 1 |
| Feldman, JM; Klatt, C; Seigler, HF; Vervaert, C | 1 |
| Hayashi, A; Kondo, T; Nagatsu, T; Narabayashi, H; Suzuki, T | 1 |
| Gamaniel, K; Osuide, G; Wambebe, C | 1 |
| Kuroda, H; Nukina, I; Ogawa, N; Ota, Z; Yamamoto, M | 1 |
| Bertoldi, M; Castellani, S; Dominici, P; Moore, PS; Voltattorni, CB | 1 |
| Chase, TN; Oh, JD; Vaughan, CL | 1 |
| Ahmed, SM; Chase, TN; Dunbar, GL; Menniti, FS; Oh, JD; Wessell, RH | 1 |
| Chillarón, J; Fernández, E; Palacín, M; Torrents, D; Zorzano, A | 1 |
| Andren, PE; Chergui, K; Svenningsson, P; Zhang, X | 1 |
| Bélanger, N; Di Paolo, T; Hadj Tahar, A; Morissette, M; Samadi, P | 1 |
| Feng, Z; Gorelenkova, O; Yang, J; Zheng, M | 1 |
| Cohen, OS; Friedman, E; Hassin-Baer, S; Inzelberg, R; Kaplan, N; Korczyn, AD; Kozlova, E; Rosset, S; Vituri, A; Yahalom, G | 1 |
| Calipari, ES; Jones, SR; Salvatore, MF | 1 |
| Carter, KM; D'Orazio, JA; Jarrett, SG; Wolf Horrell, EM | 1 |
| Isonishi, A; Kawabe, Y; Nakahara, K; Okuda, H; Tanaka, T; Tatsumi, K; Wanaka, A | 1 |
Reviews
3 review(s) available for levodopa and serine
| Article | Year |
|---|---|
[Pathogenic substances in Parkinson disease and new therapeutics considering the etiologic mechanism].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biopterins; Dopamine Agents; Droxidopa; Humans; Levodopa; Nerve Tissue; Parkinson Disease; Pyridines; Serine | 1988 |
Noradrenergic influences on dopaminergic function and the pharmacology of dihydroxyphenylserine (DOPS): implication for Parkinson's disease.
Topics: Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Carbidopa; Dopamine; Droxidopa; Levodopa; Locus Coeruleus; Myocardium; Norepinephrine; Pargyline; Parkinson Disease; Serine; Stereoisomerism; Tyrosine | 1985 |
Catecholaminergic control of gonadotropin and prolactin secretion with particular reference to the possible participation of dopamine.
Topics: Animals; Brain Mapping; Castration; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Electric Stimulation; Epinephrine; Estrogens; Female; Fenclonine; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Haloperidol; Hypothalamus; In Vitro Techniques; Levodopa; Luteinizing Hormone; Male; Norepinephrine; Pargyline; Phenoxybenzamine; Pimozide; Progesterone; Prolactin; Propranolol; Rats; Serine; Synaptic Transmission; Thiocarbamates; Thyrotropin-Releasing Hormone; Time Factors | 1974 |
Trials
2 trial(s) available for levodopa and serine
| Article | Year |
|---|---|
Madopar versus sinemet. A clinical study on their effectiveness.
Topics: Adult; Aged; Benserazide; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Serine | 1975 |
L-threo-3, 4-dihydroxyphenylserine treatment of Parkinson's disease.
Topics: Aged; Clinical Trials as Topic; Droxidopa; Electromyography; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Serine | 1985 |
Other Studies
23 other study(ies) available for levodopa and serine
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
A comparative study on the uptake and subsequent decarboxylation of monoamine precursors in cerebral microvessels.
Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Blood-Brain Barrier; Brain; Cats; Cattle; Cricetinae; Decarboxylation; Dogs; Droxidopa; Female; Guinea Pigs; Haplorhini; Humans; Levodopa; Male; Mice; Microcirculation; Microscopy, Fluorescence; Rabbits; Rats; Serine; Species Specificity; Swine | 1979 |
The effect of L-threo-DOPS on synaptic transmission to soleus motoneuron in normal subjects and patients with Parkinson's disease.
Topics: Adult; Aged; Droxidopa; Female; Humans; Levodopa; Male; Middle Aged; Motor Neurons; Muscles; Parkinson Disease; Reference Values; Serine; Synapses; Synaptic Transmission | 1987 |
[L-threo-DOPS therapy and parkinsonism].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Antiparkinson Agents; Brain; Dopamine; Droxidopa; Humans; Levodopa; Norepinephrine; Parkinson Disease; Parkinson Disease, Secondary; Pyridines; Serine; Stereotaxic Techniques | 1986 |
Clinical effects of L-threo-3,4-dihydroxyphenylserine in cases of parkinsonism and pure akinesia.
Topics: Adult; Aged; Antiparkinson Agents; Droxidopa; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Motor Skills; Parkinson Disease; Parkinson Disease, Secondary; Serine; Shy-Drager Syndrome | 1987 |
Studies on the activity of L-threo-3,4-dihydroxyphenylserine (L-DOPS) as a catecholamine precursor in the brain. Comparison with that of L-dopa.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Catecholamines; Dopamine; Droxidopa; Kinetics; Levodopa; Male; Methoxyhydroxyphenylglycol; Mice; Nialamide; Norepinephrine; Protein Precursors; Rats; Rats, Inbred Strains; Serine; Substrate Specificity | 1987 |
[Metrizamide encephalopathy in a child with hydrocephalus--effects of L-threo-DOPS on persistent disturbance of consciousness and L-dopa on extrapyramidal symptoms].
Topics: Basal Ganglia Diseases; Brain; Brain Diseases; Child; Cognition Disorders; Consciousness Disorders; Droxidopa; Electroencephalography; Extravasation of Diagnostic and Therapeutic Materials; Female; Humans; Hydrocephalus; Levodopa; Metrizamide; Serine; Tomography, X-Ray Computed | 1988 |
DL-threo-DOPS as a precursor of noradrenaline.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Carbidopa; Dopamine; Droxidopa; Levodopa; Male; Methyltyrosines; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Reserpine; Serine; Stereotyped Behavior | 1985 |
Therapy of malignant hamster insulinomas with monoamine precursors.
Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Animals; Cricetinae; Dopamine; Droxidopa; Levodopa; Neoplasms, Experimental; Norepinephrine; Pancreatic Neoplasms; Pargyline; Serine; Serotonin | 1981 |
DL-threo-3,4-dihydroxyphenylserine for freezing symptom in parkinsonism.
Topics: Aged; Antiparkinson Agents; Blood-Brain Barrier; Carboxy-Lyases; Dopamine; Droxidopa; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Norepinephrine; Parkinson Disease; Serine | 1984 |
Influence of levodopa, apomorphine and 3,4-dihydroxyphenylserine (DOPS) on strychnine-induced seizures in mice.
Topics: Animals; Apomorphine; Droxidopa; Levodopa; Mice; Phentolamine; Propranolol; Seizures; Serine; Strychnine | 1984 |
Improvement in freezing phenomenon of Parkinson's disease after DL-threo-3, 4-dihydroxyphenylserine.
Topics: Aged; Benserazide; Droxidopa; Gait; Humans; Levodopa; Male; Methoxyhydroxyphenylglycol; Parkinson Disease; Serine | 1984 |
Mutation of cysteine 111 in Dopa decarboxylase leads to active site perturbation.
Topics: 5-Hydroxytryptophan; Alanine; Animals; Base Sequence; Binding Sites; Circular Dichroism; Cysteine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kidney; Kinetics; Levodopa; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Swine | 1997 |
Effect of dopamine denervation and dopamine agonist administration on serine phosphorylation of striatal NMDA receptor subunits.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antibodies; Antiparkinson Agents; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Corpus Striatum; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Levodopa; Male; Motor Neurons; Nerve Degeneration; Oxidopamine; Parkinson Disease, Secondary; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Sulfonamides; Sympatholytics | 1999 |
NR2B selective NMDA receptor antagonist CP-101,606 prevents levodopa-induced motor response alterations in hemi-parkinsonian rats.
Topics: Animals; Excitatory Amino Acid Antagonists; Functional Laterality; Levodopa; Locomotion; Male; Neostriatum; Oxidopamine; Parkinson Disease, Secondary; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Rotation; Serine; Stereotyped Behavior; Sympathectomy, Chemical | 2004 |
Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.
Topics: Alanine; Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Amino Acids; Amino Acids, Aromatic; Animals; Arginine; Biological Transport; Blotting, Northern; Blotting, Western; Cell Lineage; Chickens; Cloning, Molecular; Cysteine; Dimerization; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Evolution, Molecular; Gene Library; Gene Silencing; Glutamine; Glycine; HeLa Cells; Humans; In Situ Hybridization; Inhibitory Concentration 50; Intestine, Small; Kidney; Kinetics; Levodopa; Mice; Molecular Sequence Data; Open Reading Frames; Pan troglodytes; Phylogeny; Proline; Protein Binding; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Transfection | 2005 |
Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Disease Models, Animal; Dopamine; Feedback; Functional Laterality; Gene Expression Regulation; Levodopa; Oxidopamine; Parkinson Disease; Peptide Fragments; Quinolines; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-3; Serine; Substance P; Sympatholytics; Tyrosine 3-Monooxygenase | 2008 |
Striatal Akt/GSK3 signaling pathway in the development of L-Dopa-induced dyskinesias in MPTP monkeys.
Topics: Animals; Antiparkinson Agents; Benzoxazoles; Cabergoline; Corpus Striatum; Disease Models, Animal; Drug Interactions; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Ergolines; Female; Glycogen Synthase Kinase 3; Levodopa; Macaca fascicularis; Oncogene Protein v-akt; Parkinsonian Disorders; Phosphorylation; Piperidines; Serine; Signal Transduction; Statistics as Topic | 2010 |
A liquid phase based C. elegans behavioral analysis system identifies motor activity loss in a nematode Parkinson's disease model.
Topics: Animals; Animals, Genetically Modified; Antiparkinson Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Electronic Data Processing; Glutamic Acid; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Motor Activity; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Serine; Software | 2012 |
Dyskinesias in patients with Parkinson's disease: effect of the leucine-rich repeat kinase 2 (LRRK2) G2019S mutation.
Topics: Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; Dyskinesia, Drug-Induced; Female; Gene Frequency; Genetic Predisposition to Disease; Glycine; Humans; Israel; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Levodopa; Longitudinal Studies; Male; Middle Aged; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Retrospective Studies; Serine; Statistics, Nonparametric; Young Adult | 2012 |
Regulation of Tyrosine Hydroxylase Expression and Phosphorylation in Dopamine Transporter-Deficient Mice.
Topics: Animals; Brain; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gene Expression Regulation; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Serine; Statistics, Nonparametric; Tyrosine 3-Monooxygenase | 2016 |
Divergence of cAMP signalling pathways mediating augmented nucleotide excision repair and pigment induction in melanocytes.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Line, Tumor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Damage; DNA Repair; Humans; Levodopa; Melanins; Melanocytes; Mutagenesis; Nucleotides; Phosphorylation; Receptor, Melanocortin, Type 1; RNA, Small Interfering; Serine; Signal Transduction; Skin Pigmentation; Ultraviolet Rays; Up-Regulation | 2017 |
Amino acid transporter Asc-1 (SLC7A10) expression is altered in basal ganglia in experimental Parkinsonism and L-dopa-induced dyskinesia model mice.
Topics: Amino Acid Transport System ASC; Amino Acid Transport System y+; Animals; Basal Ganglia; Dopamine; Dyskinesias; Levodopa; Mice; Parkinson Disease; Parkinsonian Disorders; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serine | 2023 |