Page last updated: 2024-08-17

levodopa and s-adenosylhomocysteine

levodopa has been researched along with s-adenosylhomocysteine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuller, RW; Hemrick-Leucke, SK; Perry, KW1
Claverie, N; Danzin, C; Huot-Olivier, S; Palfreyman, MG; Wagner, J1
Fuller, RW; Hemrick-Luecke, SK; Perry, KW1
Da Prada, M; Dingemanse, J; Zürcher, G1
Charlton, CG; Crowell, B1
Joseph, JA; Miller, JW; Nadeau, MR; Selhub, J; Shukitt-Hale, B; Villalobos-Molina, R1
Aquilonius, SM; Cheng, H; Ekblom, J; Gomes-Trolin, C; Löfberg, C; Oreland, L; Steinberg, A1
Charlton, CG; Liu, XX; Wilson, K1
Charlton, CG; Lamango, N; Latinwo, L; Lee, ES; Liu, XX; Zhao, WQ1
Kuhn, W; Müller, T1
Barone, P; De Bonis, ML; Galletti, P; Ingrosso, D; Longo, K; Pellecchia, MT; Russo, A; Salvatore, A; Tedeschi, G; Tessitore, A; Zappia, V1

Trials

1 trial(s) available for levodopa and s-adenosylhomocysteine

ArticleYear
Tolcapone decreases plasma levels of S-adenosyl-L-homocysteine and homocysteine in treated Parkinson's disease patients.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:6

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benzophenones; Catechol O-Methyltransferase Inhibitors; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Nitrophenols; Parkinson Disease; Prospective Studies; S-Adenosylhomocysteine; Tolcapone

2006

Other Studies

10 other study(ies) available for levodopa and s-adenosylhomocysteine

ArticleYear
Tropolone antagonism of the L-dopa-induced elevation of S-adenosylhomocysteine: S-adenosylmethionine ratio but not depletion of adrenaline in rat hypothalamus.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:6

    Topics: Animals; Catechol O-Methyltransferase Inhibitors; Epinephrine; Homocysteine; Hypothalamus; Levodopa; Male; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tropolone

1984
High-performance liquid chromatographic analysis of S-adenosylmethionine and its metabolites in rat tissues: interrelationship with changes in biogenic catechol levels following treatment with L-dopa.
    Journal of chromatography, 1984, May-04, Volume: 290

    Topics: Adrenal Glands; Animals; Brain Chemistry; Catechols; Chromatography, High Pressure Liquid; Chromatography, Liquid; Levodopa; Male; Myocardium; Pancreas; Polyamines; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine

1984
Effects of L-dopa on epinephrine concentration in rat brain: possible role of inhibition of norepinephrine N-methyltransferase by S-adenosylhomocysteine.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:1

    Topics: Animals; Epinephrine; Hypothalamus; Levodopa; Male; Monoamine Oxidase Inhibitors; Phenylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine

1982
Potent COMT inhibition by Ro 40-7592 in the periphery and in the brain. Preclinical and clinical findings.
    Advances in neurology, 1993, Volume: 60

    Topics: Animals; Benserazide; Benzophenones; Brain; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Homovanillic Acid; Humans; Levodopa; Male; Nitrophenols; Peripheral Nerves; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Tolcapone

1993
Striatal dopamine depletion, tremors, and hypokinesia following the intracranial injection of S-adenosylmethionine: a possible role of hypermethylation in parkinsonism.
    Molecular and chemical neuropathology, 1995, Volume: 26, Issue:3

    Topics: Animals; Antiparkinson Agents; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Hypokinesia; Injections, Intraventricular; Levodopa; Male; Methylation; Motor Activity; Neostriatum; Parkinson Disease; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Tremor

1995
Effect of L-Dopa and the catechol-O-methyltransferase inhibitor Ro 41-0960 on sulfur amino acid metabolites in rats.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:1

    Topics: Animals; Benzophenones; Brain; Catechol O-Methyltransferase Inhibitors; Cerebellum; Cerebral Cortex; Corpus Striatum; Enzyme Inhibitors; Hippocampus; Homocysteine; Kidney; Levodopa; Liver; Male; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Spleen

1997
Levels of L-methionine S-adenosyltransferase activity in erythrocytes and concentrations of S-adenosylmethionine and S-adenosylhomocysteine in whole blood of patients with Parkinson's disease.
    Experimental neurology, 1997, Volume: 145, Issue:2 Pt 1

    Topics: Antiparkinson Agents; Chromatography, High Pressure Liquid; Erythrocytes; Female; Humans; Levodopa; Male; Methionine Adenosyltransferase; Middle Aged; Parkinson Disease; S-Adenosylhomocysteine; S-Adenosylmethionine

1997
Effects of L-dopa treatment on methylation in mouse brain: implications for the side effects of L-dopa.
    Life sciences, 2000, Volume: 66, Issue:23

    Topics: Animals; Antiparkinson Agents; Brain Chemistry; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Levodopa; Male; Methionine Adenosyltransferase; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrophotometry, Ultraviolet

2000
L-dopa upregulates the expression and activities of methionine adenosyl transferase and catechol-O-methyltransferase.
    Experimental neurology, 2001, Volume: 171, Issue:1

    Topics: Animals; Blotting, Western; Brain; Catechol O-Methyltransferase; Dopamine; Enzyme Induction; Kidney; Levodopa; Liver; Male; Methionine Adenosyltransferase; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Time Factors; Tyrosine; Up-Regulation

2001
Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa.
    Neuroscience letters, 2010, Jan-14, Volume: 468, Issue:3

    Topics: Aged; Antiparkinson Agents; Cross-Sectional Studies; Erythrocytes; Female; Genotype; Homocysteine; Humans; Levodopa; Male; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Parkinson Disease; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine

2010