levodopa has been researched along with quinpirole in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (9.68) | 18.7374 |
| 1990's | 29 (46.77) | 18.2507 |
| 2000's | 19 (30.65) | 29.6817 |
| 2010's | 5 (8.06) | 24.3611 |
| 2020's | 3 (4.84) | 2.80 |
| Authors | Studies |
|---|---|
| Close, SP; Elliott, PJ; Walsh, DM | 1 |
| Breese, GR; Criswell, HE; Mueller, RA | 1 |
| Greiner, HE; Haase, AF; Seyfried, CA | 1 |
| Collier, TJ; Sladek, JR; Steece-Collier, K; Yurek, DM | 1 |
| Davis, A; Jenner, P; Marsden, CD | 1 |
| Di Chiara, G; Morelli, M | 1 |
| Chase, TN; Engber, TM; Kuo, S; Susel, Z | 1 |
| Schneider, JS | 1 |
| Boyce, S; Clarke, CE; Crossman, AR; Robertson, RG; Sambrook, MA | 1 |
| Heikkila, RE; Manzino, L; Sonsalla, PK | 1 |
| Jenner, P; Marsden, CD | 1 |
| Baumeister, A; Breese, GR; Frye, GD; Mueller, RA; Napier, TC | 1 |
| Goldberg, LI | 1 |
| Bentlage, C; Björklund, A; Nikkhah, G; Olsson, M | 1 |
| Asin, KE; Bednarz, L; Nikkel, A; Perner, R | 1 |
| Dawson, R; Felheim, R; Phillips, MI | 1 |
| Di Chiara, G; Fenu, S; Morelli, M; Pinna, A | 1 |
| Schmidt, WJ; Zadow, B | 1 |
| Goshima, Y; Misu, Y; Miyamae, T; Nakamura, S; Ueda, H; Yue, JL | 1 |
| Cole, DG; Hyman, SE; Kobierski, LA; Konradi, C | 1 |
| Boldry, RC; Chase, TN; Kask, AM; Papa, SM | 1 |
| Misu, Y; Okumura, F; Sato, K; Ueda, H | 1 |
| Ebinger, G; Michotte, Y; Sarre, S | 1 |
| Derbiszewska, T; Nowak, JZ; Zawilska, JB | 1 |
| Fenu, S; Morelli, M; Ongini, E; Pinna, A | 1 |
| Chase, TN; Del Dotto, P; Oh, JD | 1 |
| Bédard, PJ; Britton, DR; Grondin, R; Shiosaki, K | 1 |
| Andersen, SL; Dumont, NL; Teicher, MH | 1 |
| Drukarch, B; Morelli, M; Pinna, A; Stoof, JC | 1 |
| Andringa, G; Cools, AR; Drukarch, B; Stoof, JC; Vermeulen, RJ | 1 |
| Barlas, C; Chugh, A; Johnson, RL; Marcotte, ER; Mishra, RK; Whan, D | 1 |
| Davila, V; Pothos, EN; Przedborski, S; Schmitz, Y; Sulzer, D | 1 |
| Palmiter, RD; Szczypka, MS; Zhou, QY | 1 |
| Kannari, K; Maeda, T; Matsunaga, M; Suda, T | 1 |
| Maj, J; Rogóz, Z; Skuza, G | 1 |
| Andrén, PE; Ekesbo, A; Gunne, LM; Sonesson, C; Tedroff, J | 1 |
| Jackson, MJ; Jenner, P; Kanda, T; Kase, H; Kuwana, Y; Nakamura, J; Pearce, RK; Smith, LA | 1 |
| Jackson, M; Jenner, P; Treseder, SA | 1 |
| Jenner, P; Smith, LA; Treseder, SA | 1 |
| Carta, A; Fenu, S; Morelli, M | 1 |
| Cimini, MG; Haas, JV; Nichols, NF; Staton, BA; Svensson, KA; Tedroff, J | 1 |
| Brown, P; Harnack, D; Kupsch, A; Magill, PJ; Meissner, W; Sharott, A | 1 |
| Morikawa, H; Paladini, CA; Palmiter, RD; Robinson, S; Williams, JT | 1 |
| Bédard, PJ; Grégoire, L; Samadi, P | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Picconi, B; Rossi, S | 1 |
| Fuchs, S; Ilani, T; Strous, RD | 1 |
| Bamford, NS; Joyce, JA; Meshul, CK; Moore, C; Palmiter, RD; Robinson, S | 1 |
| Bibbiani, F; Chase, TN; Collins, MA; Kielaite, A; Oh, JD; Smith, C | 1 |
| Cauli, O; Morelli, M; Pinna, A | 1 |
| Fukuda, T; Iwata, S; Miyata, A; Nomoto, M; Shimizu, T | 1 |
| Beard, JL; Bianco, LE; Earley, CJ; Jones, BC; Wiesinger, J | 1 |
| Dimpfel, W | 1 |
| Goshima, Y; Matsushita, N; Misu, Y | 1 |
| Ballion, B; Chetrit, J; Frenois, F; Gonon, F; Murer, MG; Zold, CL | 1 |
| Hamann, M; Lange, N; Richter, A; Shashidharan, P | 1 |
| Blandini, F; Fuzzati-Armentero, MT; Ghezzi, C; Nisticò, R; Oda, A | 1 |
| Barraud, Q; Bezard, E; Ghorayeb, I; Hyacinthe, C; Tison, F | 1 |
| Cruz, AV; Delaville, C; Dupre, KB; Eyring, KW; Gerber, CM; McCoy, AJ; Walters, JR | 1 |
| Bartlett, MJ; Falk, T; Flores, AJ; Heien, ML; Parent, KL; Polt, R; Porreca, F; Root, BK; Sherman, SJ | 1 |
| Cheng, L; Li, L; Wang, Y | 1 |
| Blass, BE; Bohmann, J; Chen, PJ; Daadi, ES; Daadi, EW; Daadi, MM; Kim, J; Oh, T; Roy-Choudhury, G | 1 |
| Alberquilla, S; Coll, C; Keifman, E; Moratalla, R; Murer, MG; Reig, R; Sáez, M | 1 |
2 review(s) available for levodopa and quinpirole
| Article | Year |
|---|---|
The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Callithrix; Corpus Striatum; Disease Models, Animal; Dopamine; Ergolines; Humans; Levodopa; Macaca mulatta; Neural Pathways; Pargyline; Parkinson Disease; Parkinson Disease, Secondary; Pyridines; Quinpirole; Rats; Saimiri; Selegiline; Species Specificity; Substantia Nigra | 1986 |
Dopamine receptors and hypertension. Physiologic and pharmacologic implications.
Topics: Animals; Benzazepines; Blood Pressure; Bromocriptine; Domperidone; Dopamine; Ergolines; Fenoldopam; Humans; Hypertension; Levodopa; Quinpirole; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Vasoconstriction; Vasodilation | 1984 |
60 other study(ies) available for levodopa and quinpirole
| Article | Year |
|---|---|
Dopamine D1 and D2 receptor interactions in the MPTP-treated marmoset.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Callithrix; Dopamine Agents; Ergolines; Female; Levodopa; Male; Movement; Parkinson Disease, Secondary; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1992 |
Pharmacologic evaluation of SCH-39166, A-69024, NO-0756, and SCH-23390 in neonatal-6-OHDA-lesioned rats. Further evidence that self-mutilatory behavior induced by L-dopa is related to D1 dopamine receptors.
Topics: Animals; Animals, Newborn; Benzazepines; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Female; Levodopa; Motor Activity; Oxidopamine; Papaverine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Self Mutilation; Sympathectomy, Chemical; Tetrahydroisoquinolines | 1992 |
Neurochemical profile of EMD 45609 (carmoxirole), a dopamine DA2-receptor agonist.
Topics: Animals; Biogenic Amines; Brain; Clonidine; Corpus Striatum; Dopamine; Dopamine Agents; Drug Interactions; Ergolines; Heart; Hypothalamus; Indoles; Levodopa; Male; Motor Activity; Norepinephrine; Oxidopamine; Pyridines; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Sulpiride | 1991 |
Chronic levodopa impairs the recovery of dopamine agonist-induced rotational behavior following neural grafting.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Brain Tissue Transplantation; Dopamine; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Fetal Tissue Transplantation; Levodopa; Male; Mesencephalon; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 1991 |
Differential ability of selective and non-selective dopamine agonists to induce climbing in the rat indicates the involvement of both D-1 and D-2 receptors in this behaviour.
Topics: Amphetamine; Animals; Apomorphine; Benzazepines; Bromocriptine; Clonidine; Dopamine Agents; Ergolines; Female; Levodopa; Motor Activity; Pergolide; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Sulpiride | 1990 |
MK-801 potentiates dopaminergic D1 but reduces D2 responses in the 6-hydroxydopamine model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benserazide; Dizocilpine Maleate; Dopamine Agents; Ergolines; Hydroxydopamines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Stereotyped Behavior | 1990 |
Chronic levodopa treatment alters basal and dopamine agonist-stimulated cerebral glucose utilization.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Autoradiography; Basal Ganglia; Brain; Carbon Radioisotopes; Deoxyglucose; Dopamine Agents; Dose-Response Relationship, Drug; Ergolines; Glucose; Levodopa; Male; Neural Pathways; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Thalamus | 1990 |
Levodopa-induced dyskinesias in parkinsonian monkeys: relationship to extent of nigrostriatal damage.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Ergolines; Levodopa; Macaca fascicularis; Parkinson Disease, Secondary; Quinpirole | 1989 |
Drug-induced dyskinesia in primates rendered hemiparkinsonian by intracarotid administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Dose-Response Relationship, Drug; Ergolines; Injections, Intravenous; Levodopa; Macaca fascicularis; Movement Disorders; Parkinson Disease, Secondary; Pyridines; Quinpirole; Stereotyped Behavior | 1989 |
Interactions of D1 and D2 dopamine receptors on the ipsilateral vs. contralateral side in rats with unilateral lesions of the dopaminergic nigrostriatal pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Basal Ganglia; Benzazepines; Corpus Striatum; Denervation; Dextroamphetamine; Ergolines; Female; Flunarizine; Functional Laterality; Haloperidol; Levodopa; Neural Pathways; Parkinson Disease; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Substantia Nigra | 1988 |
Evidence that D-1 dopamine receptors contribute to the supersensitive behavioral responses induced by L-dihydroxyphenylalanine in rats treated neonatally with 6-hydroxydopamine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Dihydroxyphenylalanine; Drug Interactions; Ergolines; Female; Flupenthixol; Haloperidol; Hydroxydopamines; Levodopa; Male; Motor Activity; Oxidopamine; Pregnancy; Quinpirole; Rats; Receptors, Dopamine; Self Mutilation; Stereotyped Behavior | 1985 |
Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphine; Brain Tissue Transplantation; Carbidopa; Dextroamphetamine; Disease Models, Animal; Dopamine; Dopamine Agonists; Ergolines; Female; Fetal Tissue Transplantation; Forelimb; Functional Laterality; Levodopa; Motor Activity; Movement Disorders; Norepinephrine; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Transplantation, Heterotopic | 1995 |
Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa.
Topics: Animals; Benzopyrans; Corpus Striatum; Dopamine Agonists; Ergolines; Genes, fos; Immunohistochemistry; Levodopa; Male; Quinpirole; Rats; Rats, Sprague-Dawley | 1995 |
Dopamine receptor agonists and antagonists both inhibit dopamine secretion in LLC-PK1 cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benzazepines; Cell Line; Chlorpromazine; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Dopamine Antagonists; Epithelial Cells; Epithelium; Ergolines; Fenoldopam; Kidney; Levodopa; Phenothiazines; Quinpirole; Trifluoperazine | 1993 |
Adenosine A2 receptors interact negatively with dopamine D1 and D2 receptors in unilaterally 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Animals; Antihypertensive Agents; Autoradiography; Basal Ganglia; Benserazide; Binding Sites; Dopamine Agents; Ergolines; Levodopa; Male; Neural Pathways; Neurons; Oxidopamine; Phenethylamines; Quinolinic Acid; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic P1; Stereotyped Behavior | 1994 |
The AMPA antagonists NBQX and GYKI 52466 do not counteract neuroleptic-induced catalepsy.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Catalepsy; Dizocilpine Maleate; Drug Interactions; Ergolines; Haloperidol; Levodopa; Male; Pilot Projects; Quinoxalines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, AMPA | 1994 |
Non-effective dose of exogenously applied L-dopa itself stereoselectively potentiates postsynaptic D2 receptor-mediated locomotor activities of conscious rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Desipramine; Dopamine Agents; Ergolines; Hydrazines; Injections, Intraventricular; Levodopa; Male; Microdialysis; Motor Activity; Nerve Fibers; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereoisomerism | 1994 |
6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dopamine; Embryo, Mammalian; Ergolines; Gene Expression; Genes, fos; Levodopa; Male; Neurons; Oxidopamine; Phosphorylation; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Substantia Nigra | 1994 |
MK-801 reverses effects of chronic levodopa on D1 and D2 dopamine agonist-induced rotational behavior.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Ergolines; Excitatory Amino Acid Antagonists; Levodopa; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympatholytics | 1995 |
L-DOPA inhibits spontaneous acetylcholine release from the striatum of experimental Parkinson's model rats.
Topics: Acetylcholine; Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Drug Synergism; Ergolines; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes | 1995 |
Levodopa biotransformation in hemi-Parkinson rats: effect of dopamine receptor agonists and antagonists.
Topics: Animals; Antiparkinson Agents; Benzazepines; Biotransformation; Corpus Striatum; Denervation; Dopamine Agonists; Dopamine Antagonists; Levodopa; Male; Parkinson Disease; Quinpirole; Rats; Rats, Wistar; Sulpiride | 1996 |
Pharmacological modifications in dopaminergic neurotransmission affect the quinpirole-evoked suppression of serotonin N-acetyltransferase activity in chick retina: an impact on dopamine D4-like receptors.
Topics: Animals; Antipsychotic Agents; Arylamine N-Acetyltransferase; Chickens; Circadian Rhythm; Clozapine; Dopamine Agents; Enzyme Inhibitors; Levodopa; Male; Quinpirole; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D4; Retina; Salicylamides; Sulpiride; Synaptic Transmission | 1996 |
Adenosine A2A receptor antagonism potentiates L-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats.
Topics: Animals; Behavior, Animal; Brain Diseases; Dopamine Agonists; Drug Synergism; Gene Expression; Genes, fos; Levodopa; Male; Oxidopamine; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Dopamine D2; Substantia Nigra; Triazoles | 1997 |
Protein kinase A inhibitor attenuates levodopa-induced motor response alterations in the hemi-parkinsonian rat.
Topics: Animals; Antiparkinson Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Agents; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Levodopa; Male; Motor Activity; Parkinson Disease; Quinpirole; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Thionucleotides | 1997 |
Potential therapeutic use of the selective dopamine D1 receptor agonist, A-86929: an acute study in parkinsonian levodopa-primed monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Motor Activity; Parkinson Disease, Secondary; Quinolones; Quinpirole; Receptors, Dopamine D1; Thiophenes | 1997 |
Developmental differences in dopamine synthesis inhibition by (+/-)-7-OH-DPAT.
Topics: Age Factors; Animals; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Levodopa; Nucleus Accumbens; Prefrontal Cortex; Quinpirole; Rats; Rats, Sprague-Dawley; Salicylamides; Tetrahydronaphthalenes | 1997 |
Priming of 6-hydroxydopamine-lesioned rats with L-DOPA or quinpirole results in an increase in dopamine D1 receptor-dependent cyclic AMP production in striatal tissue.
Topics: Animals; Benzazepines; Corpus Striatum; Cyclic AMP; Dopamine; Dopamine Agonists; In Vitro Techniques; Levodopa; Male; Oxidopamine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1 | 1997 |
Dopamine receptor subtypes as targets for the pharmacotherapy of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Benzazepines; Dopamine Agonists; Haplorhini; Levodopa; Motor Activity; Parkinson Disease, Secondary; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1 | 1998 |
Modulation of dopamine receptor agonist-induced rotational behavior in 6-OHDA-lesioned rats by a peptidomimetic analogue of Pro-Leu-Gly-NH2 (PLG).
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Brain; Dopamine; Dopamine Agonists; Drug Synergism; Levodopa; Male; MSH Release-Inhibiting Hormone; Oxidopamine; Pyrrolidinones; Quinpirole; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1997 |
D2-Like dopamine autoreceptor activation reduces quantal size in PC12 cells.
Topics: Animals; Cell Size; Dopamine; Dopamine Agonists; Enzyme Activation; Levodopa; PC12 Cells; Probability; Quinpirole; Rats; Receptors, Dopamine D2; Regression Analysis; RNA, Messenger; Tyrosine 3-Monooxygenase | 1998 |
Dopamine-stimulated sexual behavior is testosterone dependent in mice.
Topics: Aggression; Analysis of Variance; Animals; Apomorphine; Benzazepines; Castration; Dopamine; Dopamine Agonists; Female; Levodopa; Male; Mice; Mice, Mutant Strains; Quinpirole; Sexual Behavior, Animal; Testosterone | 1998 |
Loss of regulation by presynaptic dopamine D2 receptors of exogenous L-DOPA-derived dopamine release in the dopaminergic denervated striatum.
Topics: Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Levodopa; Male; Microdialysis; Neurotoxins; Oxidopamine; Presynaptic Terminals; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2 | 1999 |
The anticataleptic effect of 7-OH-DPAT: are dopamine D3 receptors involved?
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Catalepsy; Dextroamphetamine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Fluphenazine; Haloperidol; Hyperkinesis; Levodopa; Locomotion; Male; Naphthalenes; Pyrrolidines; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Reserpine; Tetrahydronaphthalenes | 1999 |
Motor effects of (-)-OSU6162 in primates with unilateral 6-hydroxydopamine lesions.
Topics: Adamantane; Animals; Apomorphine; Benzazepines; Benzopyrans; Callithrix; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Piperidines; Quinpirole; Rotation | 2000 |
Combined use of the adenosine A(2A) antagonist KW-6002 with L-DOPA or with selective D1 or D2 dopamine agonists increases antiparkinsonian activity but not dyskinesia in MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Oral; Animals; Callithrix; Carbidopa; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Injections, Intraperitoneal; Levodopa; Male; Motor Activity; Parkinson Disease, Secondary; Purinergic P1 Receptor Antagonists; Purines; Quinpirole; Receptor, Adenosine A2A; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2000 |
The effects of central aromatic amino acid DOPA decarboxylase inhibition on the motor actions of L-DOPA and dopamine agonists in MPTP-treated primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Callithrix; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hydrazines; Levodopa; Male; Motor Activity; Quinolones; Quinpirole; Thiophenes; Tyrosine | 2000 |
Endogenous dopaminergic tone and dopamine agonist action.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adamantane; alpha-Methyltyrosine; Animals; Antiparkinson Agents; Apomorphine; Benzopyrans; Callithrix; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Female; Levodopa; Locomotion; Male; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Tyrosine 3-Monooxygenase | 2000 |
Alterations in GAD67, dynorphin and enkephalin mRNA in striatal output neurons following priming in the 6-OHDA model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dopamine Agonists; Down-Regulation; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Gene Expression; Glutamate Decarboxylase; Isoenzymes; Levodopa; Neostriatum; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; RNA, Messenger; Sympatholytics; Up-Regulation | 2001 |
PNU-96391A (OSU6162) antagonizes the development of behavioral sensitization induced by dopamine agonists in a rat model for Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Brain Chemistry; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Quinpirole; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics | 2002 |
Oscillatory local field potentials recorded from the subthalamic nucleus of the alert rat.
Topics: Animals; Antiparkinson Agents; Biological Clocks; Dopamine Agonists; Dyskinesias; Female; Humans; Levodopa; Male; Membrane Potentials; Middle Aged; Motor Activity; Parkinson Disease; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Reference Values; Rest; Subthalamic Nucleus; Wakefulness | 2002 |
Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism.
Topics: Amphetamine; Amphetamines; Animals; Cell Membrane; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Levodopa; Mice; Mice, Inbred C57BL; Neurons; Quinpirole; Time Factors | 2003 |
Opioid antagonists increase the dyskinetic response to dopaminergic agents in parkinsonian monkeys: interaction between dopamine and opioid systems.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Dopamine; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Endorphins; Female; Levodopa; Macaca fascicularis; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Parkinson Disease, Secondary; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission | 2003 |
Therapeutic doses of L-dopa reverse hypersensitivity of corticostriatal D2-dopamine receptors and glutamatergic overactivity in experimental parkinsonism.
Topics: Animals; Antiparkinson Agents; Basal Ganglia; Dopamine Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Levodopa; Male; Models, Animal; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Synaptic Transmission | 2004 |
Dopaminergic regulation of immune cells via D3 dopamine receptor: a pathway mediated by activated T cells.
Topics: Animals; Biological Factors; Cells, Cultured; Cytokines; Dopamine; Gene Expression Regulation; Heterotrimeric GTP-Binding Proteins; Levodopa; Lymphocyte Activation; Quinpirole; Rats; Receptors, Dopamine; RNA, Messenger; Solubility; T-Lymphocytes; Th1 Cells; Th2 Cells | 2004 |
Dopamine modulates release from corticostriatal terminals.
Topics: Animals; Corpus Striatum; Dopamine; Dopamine Agents; Exocytosis; Fluorescent Dyes; Glutamic Acid; Levodopa; Mice; Mice, Knockout; Microdialysis; Motor Cortex; Neural Pathways; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Quinpirole; Receptors, Dopamine D2; Reserpine; Tyrosine 3-Monooxygenase | 2004 |
Combined blockade of AMPA and NMDA glutamate receptors reduces levodopa-induced motor complications in animal models of PD.
Topics: Amantadine; Animals; Antiparkinson Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Haplorhini; Levodopa; Male; Motor Activity; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Rotarod Performance Test; Time Factors | 2005 |
Subchronic intermittent caffeine administration to unilaterally 6-hydroxydopamine-lesioned rats sensitizes turning behaviour in response to dopamine D(1) but not D(2) receptor agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics | 2005 |
Delayed L-DOPA-induced hyperalgesia.
Topics: Animals; Benserazide; Benzazepines; Hyperalgesia; Levodopa; Male; Mice; Quinpirole; Receptors, Dopamine D2 | 2006 |
Iron deficiency alters dopamine uptake and response to L-DOPA injection in Sprague-Dawley rats.
Topics: Animals; Brain; Brain Diseases, Metabolic; Caudate Nucleus; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Extracellular Fluid; Iron Deficiencies; Levodopa; Male; Microdialysis; Neural Pathways; Norepinephrine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Restless Legs Syndrome; RNA, Messenger; Substantia Nigra; Up-Regulation | 2008 |
Pharmacological modulation of dopaminergic brain activity and its reflection in spectral frequencies of the rat electropharmacogram.
Topics: Animals; Azepines; Brain; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Electroencephalography; Levodopa; Microelectrodes; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine D2; Sulpiride | 2008 |
In vivo antagonism of the behavioral responses to L-3-,4-dihydroxyphenylalanine by L-3-,4-dihydroxyphenylalanine cyclohexyl ester in conscious rats.
Topics: Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrazines; Levodopa; Male; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2009 |
D2 receptor stimulation, but not D1, restores striatal equilibrium in a rat model of Parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2009 |
Behavioural and pharmacological examinations in a transgenic mouse model of early-onset torsion dystonia.
Topics: Amphetamines; Animals; Anxiety; Behavior, Animal; Carbidopa; Chromans; Disease Models, Animal; Dystonia; Levodopa; Locomotion; Mice; Mice, Transgenic; Quinpirole; Raclopride | 2011 |
Single or combined treatment with L-DOPA and quinpirole differentially modulate expression and phosphorylation of key regulatory kinases in neuroblastoma cells.
Topics: Cell Line, Tumor; Cell Survival; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Glycogen Synthase Kinase 3; Humans; Levodopa; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinpirole | 2013 |
D1 receptor agonist improves sleep-wake parameters in experimental parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Electrocardiography; Electroencephalography; Electromyography; Female; Levodopa; Macaca fascicularis; Macaca mulatta; Parkinsonian Disorders; Quinpirole; Sleep; Sleep Disorders, Circadian Rhythm; Telemetry; Time Factors; Wakefulness | 2014 |
Effects of L-dopa priming on cortical high beta and high gamma oscillatory activity in a rodent model of Parkinson's disease.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dyskinesia, Drug-Induced; Gamma Rhythm; Levodopa; Male; Motor Activity; Motor Cortex; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 2016 |
The combination of the opioid glycopeptide MMP-2200 and a NMDA receptor antagonist reduced l-DOPA-induced dyskinesia and MMP-2200 by itself reduced dopamine receptor 2-like agonist-induced dyskinesia.
Topics: Animals; Antiparkinson Agents; Benzazepines; Dizocilpine Maleate; Drug Synergism; Dyskinesia, Drug-Induced; Glycopeptides; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats | 2018 |
Differential roles of two isoforms of dopamine D2 receptors in l-dopa-induced abnormal involuntary movements in mice.
Topics: Animals; Dopamine Agonists; Dopamine Antagonists; Dyskinesia, Drug-Induced; Levodopa; Male; Mice; Mice, Knockout; Motor Activity; Protein Isoforms; Quinpirole; Receptors, Dopamine D2; Salicylamides | 2021 |
Dopamine D3 receptor ligand suppresses the expression of levodopa-induced dyskinesia in nonhuman primate model of parkinson's disease.
Topics: Animals; Antiparkinson Agents; Callithrix; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; HEK293 Cells; Humans; Levodopa; Ligands; Parkinsonian Disorders; Primates; Protein Structure, Secondary; Quinpirole; Receptors, Dopamine D3 | 2022 |
D2 dopamine receptors and the striatopallidal pathway modulate L-DOPA-induced dyskinesia in the mouse.
Topics: Animals; Dopamine Agonists; Dyskinesias; Levodopa; Mice; Oxidopamine; Quinpirole; Receptors, Dopamine D2 | 2023 |