levodopa has been researched along with probenecid in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (59.26) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Kleinrok, Z; Zebrowska-Lupina, I | 1 |
| Butler, IJ; Koslow, SH | 1 |
| Sishta, SK; Templer, DI | 1 |
| Korf, J; Sebens, JB | 1 |
| Marttila, R; Rinne, UK; Sonninen, V | 1 |
| Bowers, MB; Extein, I; Roth, RH; Van Woert, M | 1 |
| Kuschinsky, K | 1 |
| Borisenko, SA | 1 |
| Caranasos, GJ; Cluff, LE; Stewart, RB | 1 |
| Garelis, E; Lal, S; Sourkes, TL; Young, SN | 1 |
| Chase, TN | 2 |
| Korf, J; Lakke, JP; Nienhuis, RJ; Schut, D; van Praag, HM | 1 |
| de Jong, PJ; Lakke, JP; Teelken, AW | 1 |
| Amaral, R; Cunha, L; Dinis, M; Gonçalves, AF; Oliveira, C | 1 |
| Huot, S; Palfreyman, MG; Wagner, J | 1 |
| Cano, J; Machado, A; Venero, JL | 1 |
| Pinto-do-O, PC; Soares-da-Silva, P | 1 |
3 review(s) available for levodopa and probenecid
| Article | Year |
|---|---|
Clinically desirable drug interactions.
Topics: Aminoglycosides; Amoxicillin; Ampicillin; Antacids; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Carbidopa; Diuretics; Drug Combinations; Drug Interactions; Drug Synergism; Humans; Hydroxamic Acids; Hypokalemia; Levodopa; Monoamine Oxidase Inhibitors; Parasympatholytics; Parkinson Disease; Penicillins; Probenecid; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1985 |
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Dihydroxyphenylalanine; Dogs; Dopamine; Fenclonine; Glycols; Haplorhini; Homovanillic Acid; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Probenecid; Serotonin; Spinal Cord; Spinal Cord Injuries; Tryptophan | 1974 |
Serotonergic mechanisms and extrapyramidal function in man.
Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors | 1974 |
24 other study(ies) available for levodopa and probenecid
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The effect of alpha-adrenolytics on the levels of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in rat's brain.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Brain Chemistry; Butyrophenones; Clonidine; Hydroxyindoleacetic Acid; Levodopa; Male; Phenoxybenzamine; Phentolamine; Probenecid; Rats; Reserpine; Serotonin | 1975 |
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Intellectual Disability; Levodopa; Male; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylketonurias; Probenecid; Seizures; Serotonin; Tyrosine | 1977 |
Levodopa in Huntingtons chorea.
Topics: Adult; Aged; Behavior; Drug Administration Schedule; Electroencephalography; Female; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Levodopa; Long-Term Care; Male; Middle Aged; Probenecid | 1976 |
Cyclic AMP in cerebrospinal fluid: accumulaiton following probenecid and biogenic amines.
Topics: Animals; Biogenic Amines; Catecholamines; Cyclic AMP; Dopamine; Haloperidol; Histamine; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Isoproterenol; Levodopa; Male; Norepinephrine; Probenecid; Rabbits; Stimulation, Chemical | 1975 |
Brain dopamine turnover and the relief of parkinsonism.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Bromocriptine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Parkinson Disease; Piperazines; Piribedil; Probenecid; Receptors, Dopamine | 1977 |
14C-homovanillic acid in the cerebrospinal fluid of parkinsonian patients after intravenous 14C-L-dopa.
Topics: Aged; Brain; Carbidopa; Carboxy-Lyases; Dopamine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Sensory Receptor Cells | 1976 |
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome | 1975 |
[Effect of ethanol and probenecid on the excretory function of the cerebral choroid plexus in rats].
Topics: Animals; Carbon Radioisotopes; Choroid Plexus; Dose-Response Relationship, Drug; Ethanol; Levodopa; Male; Probenecid; Rats; Rats, Inbred Strains; Time Factors; Tryptophan; Tyrosine | 1989 |
Clinical studies of dopaminergic mechanisms.
Topics: Antiparkinson Agents; Dioxoles; Dopamine; Drug Evaluation; Haloperidol; Homovanillic Acid; Humans; Levodopa; Parkinson Disease; Piperidines; Probenecid; Pyrimidines | 1974 |
Parkinson's disease and amine metabolites in cerebrospinal fluid: implications for L-Dopa therapy.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Depression, Chemical; Dopa Decarboxylase; Drug Combinations; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid; Stimulation, Chemical; Time Factors | 1974 |
CSF GABA levels in Parkinson's disease.
Topics: Dopamine; gamma-Aminobutyric Acid; Humans; Levodopa; Parkinson Disease; Probenecid | 1984 |
Homovanillic acid in the cerebrospinal fluid of Parkinsonian patients.
Topics: Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Probenecid | 1983 |
Value of monoamine metabolite determinations in CSF as an index of their concentrations in rat brain following various pharmacological manipulations.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid; Haloperidol; Indoles; Levodopa; Male; Probenecid; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Effect of ageing on monoamine turnover in the prefrontal cortex of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Pargyline; Prefrontal Cortex; Probenecid; Rats; Rats, Wistar; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
Antagonistic actions of renal dopamine and 5-hydroxytryptamine: effects of amine precursors on the cell inward transfer and decarboxylation.
Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney Tubules, Proximal; Levodopa; Male; Probenecid; Rats; Rats, Wistar; Renal Agents; Serotonin | 1996 |