levodopa has been researched along with phenylalanine in 94 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 28 (29.79) | 18.7374 |
1990's | 12 (12.77) | 18.2507 |
2000's | 31 (32.98) | 29.6817 |
2010's | 18 (19.15) | 24.3611 |
2020's | 5 (5.32) | 2.80 |
Authors | Studies |
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Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H | 1 |
Parkkila, AK; Parkkila, S; Puccetti, L; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Innocenti, A; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Innocenti, A; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Innocenti, A; Kaila, K; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Nishimori, I; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Ferry, JG; Innocenti, A; Scozzafava, A; Supuran, CT; Zimmerman, SA | 1 |
Arslan, O; Aydin, M; Guler, OO; Innocenti, A; Isik, S; Kockar, F; Scozzafava, A; Supuran, CT | 1 |
Hilvo, M; Innocenti, A; Parkkila, S; Scozzafava, A; Supuran, CT | 1 |
Hall, RA; Innocenti, A; Mühlschlegel, FA; Scozzafava, A; Supuran, CT | 1 |
Innocenti, A; Leewattanapasuk, W; Manole, G; Mühlschlegel, FA; Scozzafava, A; Supuran, CT | 1 |
Bertucci, A; Supuran, CT; Tambutté, S; Vullo, D; Zoccola, D | 1 |
Avdeef, A; Tam, KY | 1 |
Capasso, C; Carginale, V; De Luca, V; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Akdemir, A; Capasso, C; Carginale, V; De Luca, V; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
Capasso, C; Del Prete, S; Supuran, CT; Vullo, D | 1 |
AlOthman, Z; Capasso, C; Del Prete, S; Donald, WA; Osman, SM; Supuran, CT; Vullo, D | 1 |
Daniel, PM; Moorhouse, SR; Pratt, OE | 1 |
Butler, IJ; Holtzman, NA; Kaufman, S; Koslow, SH; Krumholz, A | 1 |
Daniel, PM; Moorhouse, RS; Pratt, OE | 1 |
Sicuteri, F | 1 |
Wirz-Justice, A | 1 |
Abroms, IF; Breslow, JL; Brewster, TG; Kaufman, S; Milstien, S; Moskowitz, MA | 1 |
Buck, R; Eberspächer, J; Lingens, F | 1 |
Antal, J; Jászsági-Nagy, E | 1 |
Cheng, LK; Fung, HL; Levitt, M | 1 |
Gancher, ST; Irwin, RP; Nutt, JG; Woodward, WR | 1 |
Slominski, A | 1 |
Coni, RJ; Cowger, M; Factor, SA; Rosenblum, EL | 1 |
Brown, JW; Freeman, GB; Ieni, JR; Soblosky, JS; Thurmond, JB | 1 |
Borchardt, RT; Hu, M | 1 |
Goshima, Y; Misu, Y; Nakamura, S | 1 |
Biasetti, S; Bracco, G; Ferraris, S; Guardamagna, O; Niederwieser, A; Ponzone, A | 1 |
Hayashi, T; Nakane, A; Naruse, H; Takesada, M; Yamazaki, K | 1 |
Lee, M; Nohta, H; Ohkura, Y; Umegae, Y | 1 |
Pulmones, MT; Sansaricq, C; Snyderman, SE | 1 |
Reimherr, FW; Ward, M; Wender, PH; Wood, DR | 1 |
Abdallah, RM; Meadows, GG; Starkey, JR | 1 |
Averbook, A; Dembure, P; Elsas, L; Epstein, C; Krause, W | 1 |
Meadows, GG; Pierson, HF | 2 |
Blonder, J; Cohen, BE; Normand, M; Peled, I; Quint, J; Szeinberg, A | 1 |
Hylka, VW; Meites, J; Sonntag, WE | 1 |
Gergely, A; Kiss, T | 1 |
Kohsaka, M; Mori, A; Takeuchi, H | 1 |
Granerus, AK; Jagenburg, R; Rödjer, S; Svanborg, A | 1 |
Blagoeva, PM | 1 |
Gelber, LR; Neumeyer, JL | 1 |
Abdallah, RM; Desai, PR; Meadows, GG; Pierson, HF | 1 |
Colombo, JP; Fünders, B; Oberwittler, C; Pietsch, M; Ullrich, K; van Eckhardstein, H; Weglage, J | 1 |
Blau, N; Dhondt, JL | 1 |
Beckner, RM; Cedarbaum, JM; Gauger, LL; Hauser, RA; Nutt, JG; Olanow, CW; Woodward, WR | 1 |
Karstaedt, PJ; Pincus, JH | 1 |
Colombo, JP; Fünders, B; Oberwittler, C; Pietsch, M; Ullrich, K; von Eckardstein, H; Weglage, J | 1 |
Dhondt, JL; Mikaeloff, Y; Pinton, F; Ponsot, G; Sevin, C | 1 |
Chiang, SC; Chien, YH; Chiu, YN; Chou, SP; Chu, SY; Huang, A; Hwu, WL; Lin, JM; Wang, TR | 1 |
Bandmann, O; Deuschl, G; Goertz, M; Hefter, H; Hoffmann, G; Jost, W; Müller, U; Oertel, W; Zöfel, P; Zschocke, J | 1 |
Maass, A; Moser, A; Scholz, J | 1 |
IMAIZUMI, R; KANIIKE, K; NAMBA, J; YOSHIDA, H | 1 |
KANIIKE, K; YOSHIDA, H | 1 |
Arnold, LA; Egami, K; Hyland, K; Jinnah, HA; Kasim, S | 1 |
Bacconi, A; Forster, I; Hajnal, A; Shoemaker, CB; Skelly, PJ; Stasiuk, S; Stetak, A; Veljkovic, E; Verrey, F | 1 |
Chien, YH; Hwu, WL; Liu, HM; Peng, SS; Tseng, WY | 1 |
Blau, N; Connolly, MB; Demos, MK; Hyland, K; Lillquist, Y; Makhseed, N; Vallance, HD; Waters, PJ | 1 |
Cheng, LY; Chiu, PC; Hsiao, KJ; Lee, NC; Liu, TT; Niu, DM | 1 |
Benkelfat, C; Casey, KF; Delaney, JS; Kolivakis, T; Leyton, M | 1 |
Benkelfat, C; Casey, KF; Leyton, M; Young, SN | 1 |
Chang, M; Fu, GX; He, C; Hsiao, KJ; Li, XW; Liu, TT; Shen, M; Shen, S; Wang, L; Yu, WM; Zhao, SP | 1 |
Fujii, Y; Furubayashi, A; Hiradate, S | 1 |
aan het Rot, M; Baker, GB; Benkelfat, C; Booij, L; Leyton, M; Young, SN | 1 |
Atluri, H; Mitra, AK; Talluri, RS | 1 |
Nucci, NV; Scott, JN; Vanderkooi, JM | 1 |
Amaral, VG; Carducci, C; Giovanniello, T; Lorenzoni, PJ; Scola, RH; Teive, HA; Werneck, LC | 1 |
Barrett, SP; Benkelfat, C; Brunelle, C; Leyton, M; Pihl, RO; Young, SN | 1 |
Giralt, E; Malakoutikhah, M; Teixidó, M | 1 |
Bozzali, M; Cametti, C; Capuani, S; Colasanti, M; D'Amore, E; Gili, T; Lazzarino, G; Maraviglia, B; Pastore, FS; Porcari, P; Russo, S; Venturini, G | 1 |
Bozzali, M; Cametti, C; Capuani, S; D'Amore, E; Gili, T; Lazzarino, G; Maraviglia, B; Muolo, M; Pastore, FS; Porcari, P; Russo, S | 1 |
Cheng, C; Gao, J; Guo, Y; Jin, X; Li, K; Li, Y; Wang, J; Wang, Z | 1 |
Blau, N; Hoffmann, GF; Kühn, AA; Opladen, T | 1 |
Alcaraz, MR; Araújo, MC; Goicoechea, HC; Gomes, Ade A | 1 |
Barth, RF; Chandra, S; Haider, SA; Huo, T; Kabalka, GW; Shaikh, AL; Yang, W | 1 |
Cao, Z; Han, B; Liu, Y; Zhu, W; Zou, H | 1 |
Kreis, K; Kuntner, C; Langer, O; Mairinger, S; Muchitsch, V; Stanek, J; Wanek, T; Wingelhofer, B | 1 |
Asselta, R; Blau, N; Cilia, R; Duga, S; Farrer, MJ; Follett, J; Goldwurm, S; Guella, I; Hattori, N; Nishioka, K; Parkkinen, L; Pezzoli, G; Priori, A; Rajput, A; Rajput, AH; Rimoldi, V; Soldà, G; Sossi, V; Stoessl, AJ; Straniero, L; Young, A | 1 |
Gao, N; Qu, X; Ren, J; Sun, Y; Zhao, C | 1 |
Azagury, A; Cho, DY; Estrellas, KM; Fiecas, M; Furtado, S; Laulicht, B; Mancini, A; Mathiowitz, E; Reineke, J | 1 |
Burman, J; Emami Khoonsari, P; Herman, S; Kultima, K; Landtblom, AM; Niemelä, V; Nyholm, D; Spjuth, O; Sundblom, J | 1 |
Dube, T; Kour, A; Kumar, A; Panda, JJ | 1 |
Cheng, C; Luo, D; Ma, Q; Qi, L; Qiao, J | 1 |
Hammoodi, HZ; Kareem, AA; Thoalnoon, OA | 1 |
Bavan, T; Binz, E; Irmler, S; Portmann, R | 1 |
Demizu, Y; Ikeda, K; Shoda, T; Tsuji, G | 1 |
11 trial(s) available for levodopa and phenylalanine
Article | Year |
---|---|
Pharmacodynamics of the hypotensive effect of levodopa in parkinsonian patients.
Topics: Amino Acids; Blood Pressure; Brain; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypotension; Infusions, Intravenous; Levodopa; Locomotion; Male; Middle Aged; Motor Activity; Parkinson Disease; Phenylalanine | 1992 |
[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Deuterium; Double-Blind Method; Humans; Levodopa; Phenylalanine; Tryptophan | 1989 |
An open trial of L-tyrosine in the treatment of attention deficit disorder, residual type.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Clinical Trials as Topic; Female; Humans; Levodopa; Male; Middle Aged; Phenylalanine; Psychiatric Status Rating Scales; Tyrosine | 1987 |
Phenylalanine alters the mean power frequency of electroencephalograms and plasma L-dopa in treated patients with phenylketonuria.
Topics: Adolescent; Analysis of Variance; Child; Double-Blind Method; Electroencephalography; Humans; Levodopa; Phenylalanine; Phenylketonurias; Regression Analysis | 1986 |
Effect of L-dopa on pattern visual evoked potentials (P-100) and neuropsychological tests in untreated adult patients with phenylketonuria.
Topics: Adult; Evoked Potentials, Visual; Frontal Lobe; Humans; Levodopa; Neuropsychological Tests; Phenylalanine; Phenylketonurias | 1994 |
Aspartame use in Parkinson's disease.
Topics: Aged; Aspartame; Humans; Levodopa; Middle Aged; Parkinson Disease, Secondary; Phenylalanine | 1993 |
The phenylalanine loading test in the differential diagnosis of dystonia.
Topics: Administration, Oral; Adult; Diagnosis, Differential; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Reference Values; Sensitivity and Specificity; Time Factors; Tyrosine | 2003 |
Cocaine craving, euphoria, and self-administration: a preliminary study of the effect of catecholamine precursor depletion.
Topics: Adult; Catecholamines; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Diet, Protein-Restricted; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Euphoria; Humans; Levodopa; Male; Phenylalanine; Self Administration; Time Factors; Tyrosine | 2005 |
Lack of effect of acute dopamine precursor depletion in nicotine-dependent smokers.
Topics: Adult; Diet, Protein-Restricted; Dopamine; Dopamine Agents; Humans; Levodopa; Male; Pain Measurement; Phenylalanine; Self Administration; Surveys and Questionnaires; Time Factors; Tobacco Use Disorder; Tyrosine | 2006 |
Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion.
Topics: Adult; Affect; Attention; Carbidopa; Central Nervous System Stimulants; Dextroamphetamine; Dopamine; Double-Blind Method; Drug Combinations; Humans; Levodopa; Male; Motivation; Neuropsychological Tests; Pain Measurement; Phenylalanine; Reaction Time; Tyrosine | 2007 |
The role of dopamine in alcohol self-administration in humans: individual differences.
Topics: Adult; Alcohol Drinking; Amino Acids; Analysis of Variance; Dopamine; Dopamine Agents; Double-Blind Method; Ethanol; Heart Rate; Humans; Individuality; Levodopa; Male; Phenylalanine; Self Administration; Tyrosine | 2008 |
83 other study(ies) available for levodopa and phenylalanine
Article | Year |
---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis | 2002 |
Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.
Topics: Amines; Amino Acids; Carbonic Anhydrases; Enzyme Activators; Isoenzymes | 2006 |
Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines.
Topics: Amines; Amino Acids; Carbonic Anhydrases; Catalysis; Enzyme Activation; Humans; Kinetics; Mitochondrial Proteins; Protein Isoforms; Structure-Activity Relationship | 2007 |
Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Carbonic Anhydrases; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Protein Isoforms; Protein Subunits | 2007 |
Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Carbonic Anhydrases; Enzyme Activation; Enzyme Activators; Humans; Isoenzymes; Molecular Sequence Data; Sequence Homology, Amino Acid | 2007 |
Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.
Topics: Amines; Amino Acids; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Conserved Sequence; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Structure; Neoplasms; Sequence Alignment; Structure-Activity Relationship | 2008 |
Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines.
Topics: Amines; Amino Acids; Binding Sites; Carbonic Anhydrase III; Carbonic Anhydrase IV; Cell Membrane; Cytosol; Enzyme Activation; Histidine; Humans; Isoenzymes; Molecular Structure; Morpholines; Serotonin; Stereoisomerism | 2008 |
Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines.
Topics: Amines; Amino Acids; Archaea; Carbonic Anhydrases; Catalysis; Molecular Structure; Phenylalanine; Stereoisomerism; Tyrosine | 2008 |
Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids.
Topics: Amino Acids; Candida albicans; Carbonic Anhydrases; Catalysis; Catalytic Domain; Cryptococcus neoformans; Drug Design; Enzyme Activation; Epinephrine; Humans; Kinetics; Models, Chemical; Protein Isoforms; Saccharomyces cerevisiae; Tryptophan | 2009 |
Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Animals; Carbonic Anhydrases; Enzyme Activators; Humans; Kinetics; Mice; Molecular Sequence Data; Protein Isoforms; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2009 |
Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids.
Topics: Amines; Amino Acids; Candida albicans; Carbonic Anhydrase I; Carbonic Anhydrases; Cryptococcus neoformans; Enzyme Activation; Structure-Activity Relationship | 2010 |
Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids.
Topics: Amines; Amino Acids; Candida glabrata; Carbonic Anhydrases; Catalytic Domain; Enzyme Activation; Humans; Kinetics; Models, Molecular; Recombinant Proteins; Structure-Activity Relationship | 2010 |
Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines.
Topics: Amines; Amino Acids; Animals; Anthozoa; Carbonic Anhydrases; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
The first activation study of a bacterial carbonic anhydrase (CA). The thermostable α-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines.
Topics: Amines; Amino Acids; Carbon Dioxide; Carbonic Anhydrases; Enzyme Activation; Gram-Negative Chemolithotrophic Bacteria; Kinetics | 2012 |
The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines.
Topics: Amines; Amino Acids; Bacteria; Carbonic Anhydrases; Catalysis; Structure-Activity Relationship; Sulfur Compounds | 2013 |
Carbonic anhydrase activators: Activation of the β-carbonic anhydrase from Malassezia globosa with amines and amino acids.
Topics: Amines; Amino Acids; Antifungal Agents; Carbonic Anhydrases; Dandruff; Dose-Response Relationship, Drug; Ligands; Malassezia; Molecular Structure; Structure-Activity Relationship | 2016 |
Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines.
Topics: Amines; Amino Acids; Burkholderia pseudomallei; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship | 2017 |
Amino acid precursors of monoamine neurotransmitters and some factors influencing their supply to the brain.
Topics: Amino Acids, Essential; Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Carbon Radioisotopes; Histidine; Levodopa; Neurotransmitter Agents; Osmolar Concentration; Phenylalanine; Protein Precursors; Rats; Tryptophan; Tyrosine | 1976 |
A disorder of biogenic amines in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Brain; Child, Preschool; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Liver; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Vanilmandelic Acid | 1978 |
Letter: Do changes in blood levels of other aromatic aminoacids influence levodopa therapy?
Topics: Amino Acids; Blood-Brain Barrier; Histidine; Humans; Levodopa; Parkinson Disease; Phenylalanine; Tryptophan | 1976 |
Hypothesis: migraine, a central biochemical dysnociception.
Topics: Adult; Animals; Apomorphine; Circadian Rhythm; Dopamine; Female; Fever; Headache; Humans; Levodopa; Lysergic Acid Diethylamide; Male; Migraine Disorders; Nervous System; Norepinephrine; Pain; Perceptual Disorders; Phenylalanine; Psilocybin; Rats; Reserpine; Serotonin; Sleep; Somatosensory Cortex; Synaptic Transmission | 1976 |
Theoretical and therapeutic potential of indolamine precursors in affective disorders.
Topics: 5-Hydroxytryptophan; Amino Acids; Bipolar Disorder; Depression; Emotions; Female; Humans; Levodopa; Male; Phenylalanine; Serotonin; Sex Factors; Tryptophan; Tyrosine | 1977 |
Dihydropteridine reductase deficiency associated with severe neurologic disease and mild hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Ascorbic Acid; Consanguinity; Dopamine; Humans; Infant; Levodopa; Liver; Male; NADH, NADPH Oxidoreductases; Nervous System Diseases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Serotonin | 1979 |
[Degradation and biosynthesis of L-phenylalanine by chloridazon-degrading bacteria].
Topics: Bacteria; Chorismate Mutase; Chromatography, Thin Layer; Enzyme Repression; Hydrolases; Levodopa; Oxygenases; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Pyridazines; Structure-Activity Relationship | 1979 |
[The effect of L-dopa and reserpine on the accumulation of 14C-methionine 14C-phenylalanine in the brain regions of rats].
Topics: Animals; Brain; Carbon Radioisotopes; Levodopa; Male; Methionine; Phenylalanine; Rats; Reserpine | 1978 |
Fluorescence reactions of fluorescamine with levodopa and its derivatives: fluorescence assay of 3-methoxy-4-hydroxyphenylalanine in levodopa dosage forms.
Topics: Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Dopamine; Fluorescamine; Fluorescence; Levodopa; Oxidation-Reduction; Phenylalanine; Spectrophotometry, Ultraviolet; Spiro Compounds | 1975 |
L-tyrosine-binding proteins on melanoma cells.
Topics: Animals; Antibodies; Blotting, Western; Carbon Radioisotopes; Chromatography, Affinity; Cricetinae; Levodopa; Melanoma; Molecular Weight; Monophenol Monooxygenase; Phenylalanine; Protein Binding; Tumor Cells, Cultured; Tyrosine | 1991 |
Paroxysmal tremor and orofacial dyskinesia secondary to a biopterin synthesis defect.
Topics: Administration, Oral; Biopterins; Extremities; Humans; Infant; Levodopa; Male; Mouth; Movement Disorders; Phenylalanine; Tremor | 1991 |
Effects of dietary tyrosine on L-dopa- and amphetamine-induced changes in locomotor activity and neurochemistry in mice.
Topics: Animals; Biogenic Monoamines; Body Weight; Brain Chemistry; Dextroamphetamine; Diet; Drug Interactions; Levodopa; Male; Mice; Motor Activity; Phenylalanine; Tyrosine | 1990 |
Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2).
Topics: 2,4-Dinitrophenol; Antihypertensive Agents; Biological Transport; Carrier Proteins; Cell Line; Dinitrophenols; Epithelial Cells; Epithelium; Glucose; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Levodopa; Models, Biological; Phenylalanine; Protein Binding; Temperature | 1990 |
L-dopa methyl ester antagonizes competitively L-dopa-induced facilitation of noradrenaline release from rat hypothalamic slices.
Topics: Animals; Binding, Competitive; Hypothalamus; In Vitro Techniques; Levodopa; Norepinephrine; Phenylalanine; Propranolol; Rats | 1990 |
Neurotransmitter therapy and diet in malignant phenylketonuria.
Topics: 5-Hydroxytryptophan; Carbidopa; Combined Modality Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Levodopa; Phenylalanine; Phenylketonurias | 1987 |
Assay for tyrosine hydroxylase by high-performance liquid chromatography with fluorescence detection.
Topics: Adrenal Medulla; Animals; Brain; Brain Chemistry; Catalase; Chromatography, High Pressure Liquid; Iron; Levodopa; Male; Phenylalanine; Rats; Spectrometry, Fluorescence; Tyrosine; Tyrosine 3-Monooxygenase | 1987 |
Successful long term therapy of biopterin deficiency.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Dihydropteridine Reductase; Female; Humans; Infant, Newborn; Levodopa; Liver; Neopterin; Phenylalanine; Phenylalanine Hydroxylase | 1987 |
Interaction between specific dietary factors and experimental chemotherapy of metastatic melanoma.
Topics: Animals; Ascorbic Acid; Diet; Female; Levodopa; Lung Neoplasms; Melanoma; Mice; Mice, Inbred Strains; Phenylalanine; Tyrosine | 1986 |
Modulation of peroxidation in murine melanoma by dietary tyrosine-phenylalanine restriction, levodopa methylester chemotherapy, and sodium ascorbate supplementation.
Topics: Animals; Ascorbic Acid; Diet; Female; Levodopa; Lipid Peroxides; Liver; Malondialdehyde; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenylalanine; Tyrosine | 1985 |
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine | 1985 |
Growth hormone restores protein synthesis in skeletal muscle of old male rats.
Topics: Age Factors; Aging; Animals; Diaphragm; Growth Hormone; Levodopa; Male; Muscle Proteins; Muscles; Phenylalanine; Rats; Rats, Inbred Strains | 1985 |
Copper(II) and nickel(II) ternary complexes of L-dopa and related compounds.
Topics: Chemical Phenomena; Chemistry; Copper; Dopamine; Hydrogen-Ion Concentration; Kinetics; Levodopa; Ligands; Nickel; Osmolar Concentration; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1985 |
[Effect of catecholamines and their analogs on the electric activity of a giant neuron identified in the subesophageal ganglia of the giant african snail (Achatina fulica Ferussac)].
Topics: Action Potentials; Animals; Catecholamines; Dopamine; Epinephrine; Homovanillic Acid; Levodopa; Mandelic Acids; Methoxyhydroxyphenylglycol; Neural Conduction; Neurons; Norepinephrine; Normetanephrine; Octopamine; Phenylalanine; Snails; Structure-Activity Relationship; Synephrine; Tyramine; Tyrosine | 1974 |
Variations in L-dopa absorption. Report of a parkinsonian patient with high plasma dopa concentration after therapeutical L-dopa dose.
Topics: Administration, Oral; Aged; Carbon Radioisotopes; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Female; Humans; Injections, Intravenous; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylalanine; Stimulation, Chemical; Sulfates; Tyrosine | 1974 |
Aminoacids--precursors of melanin synthesis in hamster melanoma.
Topics: Amino Acids; Animals; Cricetinae; Ferrous Compounds; Iron; Levodopa; Male; Melanins; Melanoma; Mesocricetus; Neoplasm Transplantation; Phenylalanine; Tryptophan; Tyrosine | 1984 |
Sodium ascorbate enhancement of carbidopa-levodopa methyl ester antitumor activity against pigmented B16 melanoma.
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Carbidopa; Cell Line; Diet; Drug Synergism; Drug Therapy, Combination; Female; Injections, Intraperitoneal; Levodopa; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1983 |
Determination of the enantiomeric purity of levodopa, methyldopa, carbidopa and tryptophan by use of chiral mobile phase high-performance liquid chromatography.
Topics: Capsules; Carbidopa; Chromatography, High Pressure Liquid; Copper; Copper Sulfate; Drug Contamination; Levodopa; Methyldopa; Phenylalanine; Stereoisomerism; Tablets; Tryptophan | 1983 |
Dietary influence of tyrosine and phenylalanine on the response of B16 melanoma to carbidopa-levodopa methyl ester chemotherapy.
Topics: Animals; Carbidopa; Diet; Drug Evaluation, Preclinical; Female; Levodopa; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1982 |
Tetrahydrobiopterin deficiency and an international database of patients.
Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Biomarkers; Biopterins; Carbidopa; Child; Dihydropteridine Reductase; GTP Cyclohydrolase; Humans; Hydro-Lyases; Information Systems; Levodopa; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Pterins; Registries | 1993 |
The effect of L-dopa infusions with and without phenylalanine challenges in parkinsonian patients: plasma and ventricular CSF L-dopa levels and clinical responses.
Topics: Amino Acids; Biological Transport; Blood-Brain Barrier; Humans; Infusions, Intravenous; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylalanine | 1993 |
Effect of L-dopa on visual evoked potentials and neuropsychological tests in adult phenylketonuria patients.
Topics: Adult; Evoked Potentials, Somatosensory; Humans; Levodopa; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Reaction Time; Treatment Outcome | 1996 |
[Progressive convulsive encephalopathy: considering a abnormality of biopterin metabolism].
Topics: 5-Hydroxytryptophan; Algeria; Anticonvulsants; Biopterins; Brain; Child, Preschool; Consanguinity; Developmental Disabilities; Diet Therapy; Epilepsy; France; Humans; Levodopa; Magnetic Resonance Imaging; Male; Neopterin; Phenylalanine; Phenylketonurias | 1999 |
Treatment and outcome of Taiwanese patients with 6-pyruvoyltetrahydropterin synthase gene mutations.
Topics: 5-Hydroxytryptophan; Base Sequence; Biopterins; DNA Mutational Analysis; Founder Effect; Humans; Infant, Newborn; Intelligence; Levodopa; Mutation; Neonatal Screening; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Taiwan; Treatment Outcome | 2001 |
Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase.
Topics: Amino Acid Sequence; Animals; Biopterins; Catalytic Domain; Dopamine; Humans; Levodopa; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Phenylalanine; Phenylalanine Hydroxylase; Protein Binding; Rats; Sequence Alignment; Substrate Specificity; Tyrosine; Tyrosine 3-Monooxygenase | 2003 |
STUDIES ON ACTIVE TRANSPORT OF L-DOPA (DIHYDROXYPHENYLALANINE) INTO BRAIN SLICES.
Topics: Acetates; Alanine; Aniline Compounds; Animals; Biological Transport, Active; Calcium; Calcium, Dietary; Cerebral Cortex; Dihydroxyphenylalanine; Glutamates; Guinea Pigs; Ions; Levodopa; Magnesium; Metabolism; Phenols; Phenylalanine; Research; Sodium; Tyrosine | 1963 |
INCREASE IN ACCUMULATION OF L-DOPA (3,4-DIHYDROXY-PHENYLALANINE) IN BRAIN SLICES BY ALCOHOL.
Topics: Alcohols; Carbon Isotopes; Cerebral Cortex; Dihydroxyphenylalanine; Ethanol; Guinea Pigs; Levodopa; Metabolism; Pharmacology; Phenylalanine; Research | 1963 |
Tetrahydrobiopterin deficiency and dopamine loss in a genetic mouse model of Lesch-Nyhan disease.
Topics: Animals; Biopterins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phenylalanine; Tyrosine | 2004 |
Aromatic amino acid transporter AAT-9 of Caenorhabditis elegans localizes to neurons and muscle cells.
Topics: Amino Acid Transport Systems; Amino Acids, Aromatic; Animals; Biological Transport; Caenorhabditis elegans; Cell Membrane; Cloning, Molecular; Cysteine; Disulfides; DNA, Complementary; Electrophysiology; Gene Silencing; Green Fluorescent Proteins; Humans; Immunohistochemistry; Ions; Kinetics; Levodopa; Microscopy, Fluorescence; Muscles; Neurons; Oocytes; Phenotype; Phenylalanine; Phylogeny; Plasmids; Promoter Regions, Genetic; Protein Structure, Secondary; Protein Structure, Tertiary; RNA, Complementary; Time Factors; Transgenes; Xenopus laevis | 2004 |
Diffusion tensor images in children with early-treated, chronic, malignant phenylketonuric: correlation with intelligence assessment.
Topics: 5-Hydroxytryptophan; Axons; Biopterins; Brain Damage, Chronic; Cerebral Cortex; Child; Child, Preschool; Combined Modality Therapy; Corpus Callosum; Diffusion Magnetic Resonance Imaging; Dominance, Cerebral; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence; Levodopa; Male; Neonatal Screening; Nerve Fibers, Myelinated; Phenylalanine; Phenylketonurias; Pregnancy | 2004 |
6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Cerebral Palsy; Child; Developmental Disabilities; Diagnostic Errors; Dopamine Agents; Female; Humans; Levodopa; Movement Disorders; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures | 2005 |
Long-term follow-up of Chinese patients who received delayed treatment for 6-pyruvoyl-tetrahydropterin synthase deficiency.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Asian People; Biopterins; Child; Child, Preschool; China; Female; Follow-Up Studies; Humans; Infant; Intellectual Disability; Levodopa; Male; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures; Time Factors | 2006 |
[Study on tetrahydrobiopterin deficiency in Northern Chinese population].
Topics: 5-Hydroxytryptophan; Asian People; Biopterins; Child, Preschool; China; Dihydropteridine Reductase; Humans; Infant; Levodopa; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases | 2006 |
Role of catechol structure in the adsorption and transformation reactions of L-DOPA in soils.
Topics: Adsorption; Catechin; Catechols; Hydrogen-Ion Concentration; Kinetics; Lactuca; Levodopa; Mucuna; Phenylalanine; Plant Growth Regulators; Soil; Structure-Activity Relationship; Tyrosine; Volcanic Eruptions | 2007 |
Functional activity of a large neutral amino acid transporter (LAT) in rabbit retina: a study involving the in vivo retinal uptake and vitreal pharmacokinetics of L-phenyl alanine.
Topics: Alanine; Amino Acid Transport System L; Amino Acids; Amino Acids, Cyclic; Aminoisobutyric Acids; Animals; Area Under Curve; Binding, Competitive; Gene Expression; Large Neutral Amino Acid-Transporter 1; Levodopa; Male; Membrane Transport Modulators; Methionine; Phenylalanine; Protein Isoforms; Rabbits; Retina | 2008 |
Coupling of complex aromatic ring vibrations to solvent through hydrogen bonds: effect of varied on-ring and off-ring hydrogen-bonding substitutions.
Topics: Amino Acids, Aromatic; Biogenic Amines; Dopamine; Epinephrine; Hydrogen Bonding; Levodopa; Models, Chemical; Norepinephrine; Phenylalanine; Quantum Theory; Solvents; Spectrophotometry, Infrared; Temperature; Tyrosine; Vibration | 2008 |
A novel missense mutation pattern of the GCH1 gene in dopa-responsive dystonia.
Topics: Child; Dopamine Agents; Dystonia; Female; GTP Cyclohydrolase; Heterozygote; Humans; Levodopa; Mutation, Missense; Phenylalanine; Tyrosine | 2007 |
Toward an optimal blood-brain barrier shuttle by synthesis and evaluation of peptide libraries.
Topics: Biological Transport; Blood-Brain Barrier; Cell Survival; Drug Carriers; Humans; Levodopa; Membranes, Artificial; Peptide Library; Peptides; Permeability; Phenylalanine; Solubility | 2008 |
L-DOPA preloading increases the uptake of borophenylalanine in C6 glioma rat model: a new strategy to improve BNCT efficacy.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain; Brain Neoplasms; Dopamine Agents; Glioma; Levodopa; Male; Phenylalanine; Rats | 2008 |
Boronophenylalanine uptake in C6 glioma model is dramatically increased by L-DOPA preloading.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Glioma; In Vitro Techniques; Levodopa; Magnetic Resonance Imaging; Male; Phenylalanine; Radiation-Sensitizing Agents; Rats; Rats, Wistar | 2009 |
Spectroscopic analyses on interaction of o-Vanillin-D-Phenylalanine, o-Vanillin-L-Tyrosine and o-Vanillin-L-Levodopa Schiff Bases with bovine serum albumin (BSA).
Topics: Animals; Benzaldehydes; Cattle; Dopamine Agents; Levodopa; Molecular Structure; Phenylalanine; Schiff Bases; Serum Albumin, Bovine; Tyrosine | 2011 |
Pitfalls in phenylalanine loading test in the diagnosis of dopa-responsive dystonia.
Topics: Administration, Oral; Adult; Biopterins; Diagnosis, Differential; Dystonia; Dystonic Disorders; Female; Humans; Levodopa; Metabolism, Inborn Errors; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Psychomotor Disorders; Tyrosine | 2013 |
The Successive Projections Algorithm for interval selection in trilinear partial least-squares with residual bilinearization.
Topics: Algorithms; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Hydroquinones; Least-Squares Analysis; Levodopa; Ofloxacin; Phenylalanine; Software; Spectrophotometry, Ultraviolet; Tryptophan; Water | 2014 |
Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models.
Topics: Animals; Boron Compounds; Brain Neoplasms; Drug Synergism; Female; Glioma; Levodopa; Melanoma; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Organ Specificity; Phenylalanine; Premedication; Tissue Distribution; Treatment Outcome | 2014 |
Diagnosis, treatment and follow-up of patients with tetrahydrobiopterin deficiency in Shandong province, China.
Topics: 5-Hydroxytryptophan; Biopterins; Child, Preschool; China; Follow-Up Studies; Genotype; Humans; Infant; Infant, Newborn; Intelligence Tests; Levodopa; Mutation; Neopterin; Phenylalanine; Phenylketonurias; Treatment Outcome | 2015 |
Preloading with L-BPA, L-tyrosine and L-DOPA enhances the uptake of [
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Caco-2 Cells; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Humans; Levodopa; Mice; Neoplasms, Experimental; Phenylalanine; Propionates; Tyrosine; Up-Regulation | 2016 |
DNAJC12 and dopa-responsive nonprogressive parkinsonism.
Topics: Adult; alpha-Synuclein; Amyloid beta-Peptides; Antiparkinson Agents; Biogenic Amines; Brain; DNA Mutational Analysis; DNA-Binding Proteins; Family Health; Female; Humans; Levodopa; Male; Middle Aged; Mutation; Parkinsonian Disorders; Phenylalanine; Repressor Proteins; Sequestosome-1 Protein; tau Proteins; Young Adult | 2017 |
Stereoselective Nanozyme Based on Ceria Nanoparticles Engineered with Amino Acids.
Topics: Antiparkinson Agents; Catalysis; Cerium; Coenzymes; Dihydroxyphenylalanine; Humans; Kinetics; Levodopa; Metal Nanoparticles; Oxidation-Reduction; Particle Size; Phenylalanine; Stereoisomerism; Surface Properties | 2017 |
Time-dependent mucoadhesion of conjugated bioadhesive polymers.
Topics: Acrylic Resins; Adhesiveness; Adhesives; Animals; Butadienes; Hydrogen Bonding; Intestinal Mucosa; Intestine, Small; Levodopa; Maleic Anhydrides; Phenylalanine; Polymerization; Rats; Time Factors; Tissue Culture Techniques; Tyrosine | 2019 |
Alterations in the tyrosine and phenylalanine pathways revealed by biochemical profiling in cerebrospinal fluid of Huntington's disease subjects.
Topics: Adult; Aged; Biomarkers; Dopamine; Female; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Phenylalanine; Thyroxine; Tyrosine | 2019 |
Anti-Amyloidogenic and Fibril-Disaggregating Potency of the Levodopa-Functionalized Gold Nanoroses as Exemplified in a Diphenylalanine-Based Amyloid Model.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Gold; Humans; Levodopa; Peptide Fragments; Phenylalanine | 2022 |
Dipeptide-Capped Copper Nanoparticles as Chiral Nanozymes for Colorimetric Enantioselective Recognition of 3,4-Dihydroxy-d,l-phenylalanine.
Topics: Colorimetry; Copper; Cysteine; Histidine; Levodopa; Metal Nanoparticles; Peroxidases; Phenylalanine; Stereoisomerism | 2023 |
Neurotransmitters Disorders with Mild Hyperphenylalaninemia: The Ones That Should Not Be Missed.
Topics: Child; Diet; Humans; Levodopa; Phenylalanine; Phenylketonurias; Serotonin | 2023 |
Ability of Latilactobacillus curvatus FAM25164 to produce tryptamine: Identification of a novel tryptophan decarboxylase.
Topics: Amino Acids; Aromatic-L-Amino-Acid Decarboxylases; Escherichia coli; Lactobacillus; Levodopa; Phenylalanine; Tryptamines; Tyrosine | 2023 |
Discovery of non-proteinogenic amino acids inhibiting biofilm formation by S. aureus and methicillin-resistant S. aureus.
Topics: Amino Acids; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Drug Discovery; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship | 2021 |