Compounds > levodopa
Page last updated: 2024-08-17

levodopa and osu 6162

levodopa has been researched along with osu 6162 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrén, PE; Ekesbo, A; Gunne, LM; Tedroff, J1
Carlsson, A; Fasth, KJ; Hartvig, P; Långström, B; Neu, H; Sonesson, C; Tedroff, J; Torstenson, R; Waters, N1
Andrén, PE; Ekesbo, A; Gunne, LM; Sonesson, C; Tedroff, J1
Bangassoro, E; Bédard, PJ; Ekesbo, A; Grégoire, L; Hadj Tahar, A; Svensson, KA; Tedroff, J1
Andrén, PE; Gunne, L; Hurd, YL; Pirker, W; Pontén, H; Tedroff, J1
Cimini, MG; Haas, JV; Nichols, NF; Staton, BA; Svensson, KA; Tedroff, J1

Other Studies

6 other study(ies) available for levodopa and osu 6162

ArticleYear
(-)-OSU 6162 inhibits levodopa-induced dyskinesias in a monkey model of Parkinson's disease.
    Neuroreport, 1997, Jul-28, Volume: 8, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Callithrix; Carbidopa; Dopamine Antagonists; Levodopa; Male; Motor Activity; Parkinson Disease, Secondary; Piperidines; Posture; Raclopride; Salicylamides

1997
Effects of the substituted (S)-3-phenylpiperidine (-)-OSU6162 on PET measurements in subhuman primates: evidence for tone-dependent normalization of striatal dopaminergic activity.
    Synapse (New York, N.Y.), 1998, Volume: 28, Issue:4

    Topics: Animals; Biopterins; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Female; Levodopa; Macaca mulatta; Piperidines; Reference Values; Tomography, Emission-Computed; Tyrosine

1998
Motor effects of (-)-OSU6162 in primates with unilateral 6-hydroxydopamine lesions.
    European journal of pharmacology, 2000, Feb-18, Volume: 389, Issue:2-3

    Topics: Adamantane; Animals; Apomorphine; Benzazepines; Benzopyrans; Callithrix; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Piperidines; Quinpirole; Rotation

2000
Effects of acute and repeated treatment with a novel dopamine D2 receptor ligand on L-DOPA-induced dyskinesias in MPTP monkeys.
    European journal of pharmacology, 2001, Feb-02, Volume: 412, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Benserazide; Dopamine Agents; Dopamine Antagonists; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Macaca fascicularis; Motor Activity; Parkinsonian Disorders; Piperidines; Receptors, Dopamine D2

2001
Coadministration of (-)-OSU6162 with l-DOPA normalizes preproenkephalin mRNA expression in the sensorimotor striatum of primates with unilateral 6-OHDA lesions.
    Experimental neurology, 2001, Volume: 169, Issue:1

    Topics: Animals; Autoradiography; Callithrix; Caudate Nucleus; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Drug Administration Schedule; Drug Therapy, Combination; Enkephalins; Female; In Situ Hybridization; Injections, Subcutaneous; Levodopa; Ligands; Male; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Protein Precursors; Putamen; RNA, Messenger; Tritium

2001
PNU-96391A (OSU6162) antagonizes the development of behavioral sensitization induced by dopamine agonists in a rat model for Parkinson's disease.
    Neuropharmacology, 2002, Volume: 43, Issue:5

    Topics: Animals; Antiparkinson Agents; Behavior, Animal; Brain Chemistry; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Piperidines; Quinpirole; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics

2002