Page last updated: 2024-08-17

levodopa and nitecapone

levodopa has been researched along with nitecapone in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (20.00)	18.7374
1990's	8 (80.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Borisenko, SA; Männistö, PT; Törnwall, M; Tuomainen, P; Tuominen, RK	1
Männistö, PT; Törnwall, M	1
Cedarbaum, JM; Guttman, M; Leger, G	1
Gordin, A; Järvinen, M; Kaakkola, S; Nissinen, E; Pentikäinen, PJ; Rita, H; Schultz, E; Wikberg, T	1
Cedarbaum, JM; Guttman, M; Léger, G; Reches, A	1
Etemadzadeh, E; Kaakkola, S; Lindén, IB; Männistö, P; Nissinen, E; Pohto, P	1
Kaakkola, S; Lindén, IB; Männistö, PT; Nissinen, E; Pohto, P; Schultz, E	1
Gordin, A; Kaakkola, S; Männistö, PT	1
Calne, DB; Chan, GL; Doudet, DJ; Holden, JE; Morrison, KS; Pate, BD; Ruth, TJ	1
Martínez-Martín, P; O'Brien, CF	1

Reviews

2 review(s) available for levodopa and nitecapone

Article	Year
General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase. General pharmacology, 1994, Volume: 25, Issue:5 Topics: Animals; Behavior, Animal; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Dihydroxyphenylalanine; Humans; Levodopa; Microdialysis; Nitriles; Nitrophenols; Pentanones; Tolcapone; Tomography, Emission-Computed	1994
Extending levodopa action: COMT inhibition. Neurology, 1998, Volume: 50, Issue:6 Suppl 6 Topics: Antiparkinson Agents; Benzophenones; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Levodopa; Nitriles; Nitrophenols; Parkinson Disease; Pentanones; Tolcapone	1998

Article

Year

General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase.

General pharmacology, 1994, Volume: 25, Issue:5

Topics: Animals; Behavior, Animal; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Dihydroxyphenylalanine; Humans; Levodopa; Microdialysis; Nitriles; Nitrophenols; Pentanones; Tolcapone; Tomography, Emission-Computed

1994

Extending levodopa action: COMT inhibition.

Neurology, 1998, Volume: 50, Issue:6 Suppl 6

Topics: Antiparkinson Agents; Benzophenones; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Levodopa; Nitriles; Nitrophenols; Parkinson Disease; Pentanones; Tolcapone

1998

Other Studies

8 other study(ies) available for levodopa and nitecapone

Article	Year
Effect of nitecapone and clorgyline, given intracerebro-ventricularly on L-dopa metabolism in the rat brain. Neuroreport, 1992, Volume: 3, Issue:7 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carbidopa; Catechols; Cerebral Ventricles; Clorgyline; Corpus Striatum; Dopamine; Homovanillic Acid; Hypothalamus; Injections, Intraventricular; Levodopa; Male; Pentanones; Prolactin; Rats; Rats, Wistar; Thyrotropin	1992
Acute toxicity of three new selective COMT inhibitors in mice with special emphasis on interactions with drugs increasing catecholaminergic neurotransmission. Pharmacology & toxicology, 1991, Volume: 69, Issue:1 Topics: Amphetamine; Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Clorgyline; Convulsants; Desipramine; Drug Interactions; Lethal Dose 50; Levodopa; Male; Mice; Motor Activity; Nitriles; Nomifensine; Pentanones; Selegiline; Synaptic Transmission; Yohimbine	1991
Reduction of circulating 3-O-methyldopa by inhibition of catechol-O-methyltransferase with OR-611 and OR-462 in cynomolgus monkeys: implications for the treatment of Parkinson's disease. Clinical neuropharmacology, 1991, Volume: 14, Issue:4 Topics: Animals; Catechol O-Methyltransferase Inhibitors; Catechols; Levodopa; Macaca fascicularis; Male; Nitriles; Parkinson Disease; Pentanones; Tyrosine	1991
Effect of a novel catechol-O-methyltransferase inhibitor, nitecapone, on the metabolism of L-dopa in healthy volunteers. Clinical neuropharmacology, 1990, Volume: 13, Issue:5 Topics: Adult; Blood Pressure; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Electrocardiography; Erythrocytes; Heart Rate; Humans; Intestinal Absorption; Levodopa; Male; Pentanones	1990
Effect of nitecapone (OR-462) on the pharmacokinetics of levodopa and 3-O-methyldopa formation in cynomolgus monkeys. Clinical neuropharmacology, 1990, Volume: 13, Issue:6 Topics: Animals; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Levodopa; Macaca fascicularis; Male; Pentanones; Tyrosine	1990
Favorable effect of catechol-O-methyltransferase inhibition by OR-462 in experimental models of Parkinson's disease. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1 Topics: Animals; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Ketones; Levodopa; Male; Mice; Motor Activity; Parkinson Disease; Pentanones; Rats; Rats, Inbred Strains; Rotation	1988
Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat. European journal of pharmacology, 1988, Aug-24, Volume: 153, Issue:2-3 Topics: Animals; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Drug Interactions; Duodenum; Erythrocytes; In Vitro Techniques; Ketones; Levodopa; Liver; Male; Pentanones; Rats; Rats, Inbred Strains; Tyrosine	1988
Effects of monoamine oxidase and catechol-O-methyltransferase inhibition on dopamine turnover: a PET study with 6-[18F]L-DOPA. European journal of pharmacology, 1997, Sep-03, Volume: 334, Issue:1 Topics: Animals; Antiparkinson Agents; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catechols; Dopamine; Enzyme Inhibitors; Fluorine Radioisotopes; Levodopa; Macaca fascicularis; Monoamine Oxidase Inhibitors; Nitrophenols; Pentanones; Pilot Projects; Tolcapone; Tomography, Emission-Computed; Visual Cortex	1997