levodopa has been researched along with nicotine in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (11.32) | 18.7374 |
| 1990's | 6 (11.32) | 18.2507 |
| 2000's | 18 (33.96) | 29.6817 |
| 2010's | 21 (39.62) | 24.3611 |
| 2020's | 2 (3.77) | 2.80 |
| Authors | Studies |
|---|---|
| Jolivette, LJ; Ward, KW | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Anisimov, VN | 1 |
| Gateau, G; Meinel, R; Strudel, G | 1 |
| Andreeva, NI; Mashkovskiĭ, MD | 1 |
| Hollister, LE | 1 |
| Alhava, E; Klinge, E; Mansner, R | 1 |
| Cheung, BS; Money, KE | 1 |
| Goshima, Y; Misu, Y; Miyamae, T; Nakamura, S; Yue, JL | 1 |
| Goshima, Y; Kubo, T; Misu, Y; Miyamae, T; Nakamura, S; Yue, JL | 1 |
| Goshima, Y; Kosaka, K; Miki, K; Misu, Y; Miyamae, T; Nakamura, S | 1 |
| Brenci, S; Indiveri, F; Lotti, G; Musso, NR | 1 |
| Lloyd, GK; Menzaghi, F; Schneider, JS; Tinker, JP; Van Velson, M | 1 |
| Domino, EF; Ni, L; Zhang, H | 1 |
| Danysz, W | 1 |
| Cooper, T; Hashim, A; Lajtha, A; Lonow, R; Rossi, S; Sershen, H; Singer, S; Verzosa, S | 1 |
| Bordia, T; Clementi, F; Fan, H; Gotti, C; Kulak, JM; McIntosh, JM; Quik, M; Vailati, S | 1 |
| Fukumoto, D; Harada, N; Kakiuchi, T; Miyasato, K; Nishiyama, S; Tsukada, H | 1 |
| Agnihotri, N; Mothersill, C; Poon, RC; Seymour, C | 1 |
| Abin-Carriquiry, JA; Costa, G; Dajas, F; Ferreira, M; Urbanavicius, J; Wonnacott, S | 1 |
| Cox, H; Di Monte, D; Langston, JW; O'Leary, K; Parameswaran, N; Quik, M | 1 |
| Annat, G; Boussouar, A; Dalmaz, Y; Mahlière, S; Pequignot, J; Pequignot, JM; Perrin, D; Peyronnet, J; Viale, JP | 1 |
| Fujii, M; Funabashi, T; Goshima, Y; Murota, Y; Sugiyama, Y; Takahashi, T; Yagami, T | 1 |
| Bordia, T; Campos, C; Huang, L; Quik, M | 1 |
| Domino, EF; Harada, N; Tsukada, H | 1 |
| Decamp, E; Schneider, JS | 1 |
| Bordia, T; Campos, C; Huang, LZ; Parameswaran, N; Perez, XA; Quik, M | 1 |
| Bordia, T; Campos, C; McIntosh, JM; Quik, M | 1 |
| Domino, EF; Jutkiewicz, EM; Ohmura, Y | 1 |
| Grady, SR; Huang, LZ; Quik, M | 1 |
| Day, BL; Lees, AJ; Ling, H; Petrovic, I | 1 |
| Grady, SR; Hrachova, M; Huang, LZ; Mallela, A; McIntosh, JM; Park, KM; Quik, M | 1 |
| Bharath, MM; Harish, G; Mythri, RB | 1 |
| Bordia, T; Chin, M; Mallela, A; McIntosh, JM; Perez, XA; Quik, M | 1 |
| Bordia, T; McIntosh, JM; Quik, M | 1 |
| Ly, J; Mallela, A; Quik, M; Zhang, D | 1 |
| Bencherif, M; Carroll, FI; Letchworth, S; Mallela, A; Quik, M; Sohn, D; Zhang, D | 1 |
| Gan, J; Liu, ZG; Pan, JL; Xie, CL; Zhang, SF | 1 |
| Bordia, T; Drenan, RM; McGregor, M; McIntosh, JM; Quik, M | 1 |
| Abbar, M; Brunel, L; Fond, G; Lancon, C; Lopez, R; Macgregor, A; Micoulaud-Franchi, JA; Miot, S; Repantis, D; Richieri, R | 1 |
| Bordia, T; Heiss, J; Perez, XA; Quik, M; Zhang, D | 1 |
| Domingos, J; Hägglund, M; Riggare, S; Stamford, JA; Sturr, J; Svenningsson, P; Unruh, KT | 1 |
| Koski, SK; Leino, S; Rannanpää, S; Salminen, O | 1 |
| Drucker-Colín, R; Enríquez-Traba, J; García-Montes, JR; Moratalla, R; Ruiz-DeDiego, I; Solís, O | 1 |
| Kohtala, S; Koski, SK; Leino, S; Rannanpää, S; Rantamäki, T; Salminen, O | 1 |
| Torrey, EF | 1 |
| Aschner, M; Getachew, B; Tizabi, Y | 1 |
8 review(s) available for levodopa and nicotine
| Article | Year |
|---|---|
Drugs and sexual behavior in man.
Topics: Amyl Nitrite; Barbiturates; Caffeine; Cannabis; Erectile Dysfunction; Ethanol; Gonadal Steroid Hormones; Humans; Levodopa; Lithium; Male; Nicotine; Opium; Sexual Behavior; Thioridazine | 1975 |
Review on the relationship between nicotinic acetylcholine receptors and dopaminergic neurotransmission in the central nervous system--dopa is an endogenous neuroactive substance.
Topics: Animals; Catecholamines; Corpus Striatum; Dihydroxyphenylalanine; In Vitro Techniques; Levodopa; Motor Activity; Nicotine; Rats; Receptors, Nicotinic; Synapses | 1993 |
Neurotoxicity as a mechanism for neurodegenerative disorders: basic and clinical aspects.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Humans; Levodopa; Nerve Growth Factor; Neuroprotective Agents; Nicotine; Parkinson Disease | 2001 |
Multiple roles for nicotine in Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Corpus Striatum; Humans; Levodopa; Motor Skills; Neuroprotective Agents; Nicotine; Nicotinic Agonists; Parkinson Disease; Receptors, Nicotinic; Smoking; Substantia Nigra | 2009 |
Therapeutic potential of natural products in Parkinson's disease.
Topics: Animals; Biological Products; Botulinum Toxins; Humans; Levodopa; Neuroprotective Agents; Nicotine; Parkinson Disease; Patents as Topic; Phytic Acid; Phytotherapy; Piper nigrum; Plant Extracts; Zingiber officinale | 2012 |
Effect of nicotine on L-dopa-induced dyskinesia in animal models of Parkinson's disease: a systematic review and meta-analysis.
Topics: Animals; Antiparkinson Agents; Dyskinesia, Drug-Induced; Ganglionic Stimulants; Levodopa; Nicotine; Parkinsonian Disorders | 2014 |
Innovative mechanisms of action for pharmaceutical cognitive enhancement: A systematic review.
Topics: Adult; Attention; Benzhydryl Compounds; Central Nervous System Stimulants; Cognition; Humans; Levodopa; Male; Memory, Episodic; Methylphenidate; Modafinil; Nicotine; Nootropic Agents | 2015 |
Novel Pharmacotherapies in Parkinson's Disease.
Topics: Animals; Antiparkinson Agents; Brain; Butyrates; Dopamine Agents; Dopaminergic Neurons; Drug Therapy, Combination; Humans; Levodopa; Nicotine; Parkinson Disease | 2021 |
45 other study(ies) available for levodopa and nicotine
| Article | Year |
|---|---|
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Pharmacological study of cholinergic mechanisms of compensatory ovarian hypertrophy in rats.
Topics: Animals; Arecoline; Benactyzine; Castration; Diethylstilbestrol; Diphenylacetic Acids; Disulfiram; Female; Hypertrophy; Levodopa; Nicotine; Ovary; Parasympatholytics; Parasympathomimetics; Rats | 1978 |
[Fluorogenic amines in the notochords of chick embryos treated by cholinergics].
Topics: Animals; Atropine; Biogenic Amines; Carbachol; Chick Embryo; Levodopa; Microscopy, Fluorescence; Nicotine; Norepinephrine; Parasympathomimetics; Propranolol; Reserpine; Spine | 1977 |
[The pharmacologic basis of the antidepressive activity of the new psychotropic preparation pyrazidol].
Topics: 5-Hydroxytryptophan; Acetylcholine; Amphetamine; Animals; Antidepressive Agents; Arecoline; Blood Pressure; Cats; Dogs; Drug Synergism; Epinephrine; Gastrointestinal Motility; Hexobarbital; Indoles; Levodopa; Nicotine; Norepinephrine; Phenethylamines; Pyrazines; Rabbits; Rats; Reserpine; Tryptamines | 1975 |
Nicotine hypothermia and brain nicotine and catecholamine levels in the mouse.
Topics: Animals; Body Temperature; Brain; Brain Chemistry; Chemoreceptor Cells; Depression, Chemical; Dopamine; Hexamethonium Compounds; Levodopa; Male; Mecamylamine; Methyltyrosines; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Norepinephrine; Time Factors | 1974 |
Another function of the inner ear: facilitation of the emetic response to poisons.
Topics: Animals; Apomorphine; Dogs; Ear, Inner; Levodopa; Lobeline; Male; Nicotine; Pilocarpine; Poisoning; Vomiting | 1983 |
Endogenously released DOPA is probably relevant to nicotine-induced increases in locomotor activities of rats.
Topics: alpha-Methyltyrosine; Animals; Corpus Striatum; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Injections, Intraventricular; Levodopa; Male; Mecamylamine; Methyltyrosines; Motor Activity; Nerve Fibers; Nicotine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tyrosine 3-Monooxygenase | 1993 |
Ventral tegmental injection of nicotine induces locomotor activity and L-DOPA release from nucleus accumbens.
Topics: Animals; Levodopa; Locomotion; Male; Mecamylamine; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 1996 |
L-tyrosine and nicotine induce synthesis of L-Dopa and norepinephrine in human lymphocytes.
Topics: Acetylcholine; Adult; Blood Cells; Female; Humans; Levodopa; Lymphocytes; Male; Muscarine; Nicotine; Norepinephrine; Tyrosine | 1997 |
Nicotinic acetylcholine receptor agonist SIB-1508Y improves cognitive functioning in chronic low-dose MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Attention; Cognition Disorders; Conditioning, Operant; Discrimination Learning; Dopamine Agents; Female; Levodopa; Macaca fascicularis; Macaca nemestrina; Male; Memory, Short-Term; Nicotine; Nicotinic Agonists; Pattern Recognition, Visual; Pyridines; Pyrrolidines; Receptors, Nicotinic; Space Perception | 1999 |
Nicotine alone and in combination with L-DOPA methyl ester or the D(2) agonist N-0923 in MPTP-induced chronic hemiparkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Dopamine Agonists; Drug Interactions; Female; Levodopa; Macaca nemestrina; Motor Activity; Nicotine; Parkinson Disease, Secondary; Receptors, Dopamine D2; Rotation; Tetrahydronaphthalenes; Thiophenes | 1999 |
Nicotine-induced changes in neurotransmitter levels in brain areas associated with cognitive function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cognition; Dopamine; Hydroxyindoleacetic Acid; Levodopa; Male; Neurotransmitter Agents; Nicotine; Norepinephrine; Organ Specificity; Rats; Rats, Sprague-Dawley; Serotonin | 2004 |
Subunit composition of nicotinic receptors in monkey striatum: effect of treatments with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine or L-DOPA.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alkaloids; Amino Acid Sequence; Animals; Antibodies; Autoradiography; Azocines; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Corpus Striatum; Humans; Iodine Radioisotopes; Levodopa; Molecular Sequence Data; Nicotine; Protein Subunits; Pyridines; Quinolizines; Receptors, Nicotinic; Saimiri | 2005 |
Nicotine modulates dopamine synthesis rate as determined by L-[beta-11C]DOPA: PET studies compared with [11C]raclopride binding in the conscious monkey brain.
Topics: Acetylcholine; Animals; Binding, Competitive; Brain; Carbon Radioisotopes; Cerebellum; Consciousness; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Levodopa; Macaca mulatta; Male; Neural Pathways; Nicotine; Positron-Emission Tomography; Presynaptic Terminals; Raclopride; Synaptic Transmission | 2005 |
Bystander effects of ionizing radiation can be modulated by signaling amines.
Topics: Animals; Apoptosis; Bystander Effect; Calcium; Cell Line; Gamma Rays; Glycine; Humans; Levodopa; Mice; Mice, Inbred C57BL; Nicotine; Oncorhynchus mykiss; Receptors, Serotonin, 5-HT3; Selegiline; Serotonin; Signal Transduction; Skin; Urinary Bladder | 2007 |
Nicotine induces tyrosine hydroxylase plasticity in the neurodegenerating striatum.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Axons; Corpus Striatum; Denervation; Dopamine; Down-Regulation; Levodopa; Male; Nerve Degeneration; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2007 |
Nicotine reduces levodopa-induced dyskinesias in lesioned monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Circadian Rhythm; Dyskinesia, Drug-Induced; Levodopa; Nicotine; Nicotinic Agonists; Parkinsonian Disorders; Saimiri; Substantia Nigra; Time Factors | 2007 |
Prenatal nicotine alters maturation of breathing and neural circuits regulating respiratory control.
Topics: Age Factors; Animals; Animals, Newborn; Brain Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Embryo, Mammalian; Female; Hypoxia; Levodopa; Male; Nicotine; Nicotinic Agonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Respiration; Respiratory System; Tidal Volume; Tyrosine 3-Monooxygenase | 2008 |
DOPA cyclohexyl ester, a DOPA antagonist, blocks the depressor responses elicited by microinjections of nicotine into the nucleus tractus solitarii of rats.
Topics: Animals; Blood Pressure; Carbachol; Cardiovascular System; Cholinergic Agonists; Excitatory Postsynaptic Potentials; Heart Rate; In Vitro Techniques; Levodopa; Male; Mecamylamine; Microinjections; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Solitary Nucleus | 2008 |
Continuous and intermittent nicotine treatment reduces L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias in a rat model of Parkinson's disease.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Infusion Pumps; Levodopa; Male; Nicotine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 2008 |
Positron emission tomographic measure of brain dopamine dependence to nicotine as a model of drugs of abuse.
Topics: Animals; Behavior, Animal; Carbon Radioisotopes; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Levodopa; Macaca mulatta; Male; Nicotine; Nicotinic Agonists; Positron-Emission Tomography; Tobacco Use Disorder | 2009 |
Interaction between nicotinic and dopaminergic therapies on cognition in a chronic Parkinson model.
Topics: Animals; Attention; Cognition; Cues; Discrimination Learning; Disease Models, Animal; Dopamine Agents; Drug Combinations; Drug Interactions; Injections, Intramuscular; Injections, Intravenous; Levodopa; Macaca mulatta; Male; Memory; MPTP Poisoning; Nicotine; Nicotinic Agonists; Phenols; Pyrrolidines; Reaction Time; Task Performance and Analysis | 2009 |
Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitization.
Topics: Amphetamine; Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Central Nervous System Stimulants; Cocaine; Conotoxins; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Male; Mecamylamine; Neostriatum; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stereotyped Behavior | 2010 |
L-DOPA attenuates nicotine withdrawal-induced behaviors in rats.
Topics: Animals; Behavior, Animal; Depression; Dopamine Agents; Levodopa; Male; Motor Activity; Nicotine; Rats; Rats, Sprague-Dawley; Smoking Cessation; Substance Withdrawal Syndrome | 2011 |
Nicotine reduces L-DOPA-induced dyskinesias by acting at beta2* nicotinic receptors.
Topics: Animals; Antiparkinson Agents; Autoradiography; Bridged Bicyclo Compounds, Heterocyclic; Corpus Striatum; Cotinine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Oxidopamine; Pyridines; Receptors, Nicotinic; Substantia Nigra; Sympatholytics | 2011 |
Smoking-induced transient motor deterioration in a levodopa-treated patient with Parkinson's disease.
Topics: Administration, Intranasal; Female; Humans; Levodopa; Middle Aged; Motor Skills Disorders; Nicotine; Parkinson Disease; Smoking | 2012 |
Role for α6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice.
Topics: Animals; Antiparkinson Agents; Autoradiography; Benserazide; Cotinine; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dyskinesia, Drug-Induced; Hydroxydopamines; Levodopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Parkinsonian Disorders; Receptors, Nicotinic | 2012 |
Nicotine-mediated improvement in L-dopa-induced dyskinesias in MPTP-lesioned monkeys is dependent on dopamine nerve terminal function.
Topics: Animals; Corpus Striatum; Dopamine; Dopamine Agonists; Dyskinesia, Drug-Induced; Female; Levodopa; Male; MPTP Poisoning; Nicotine; Nicotinic Agonists; Presynaptic Terminals; Receptors, Nicotinic; Saimiri | 2013 |
The nicotine-mediated decline in l-dopa-induced dyskinesias is associated with a decrease in striatal dopamine release.
Topics: Animals; Antiparkinson Agents; Autoradiography; Corpus Striatum; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Levodopa; Male; Nicotine; Nicotinic Agonists; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2013 |
Nicotine reduces established levodopa-induced dyskinesias in a monkey model of Parkinson's disease.
Topics: Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Cotinine; Data Interpretation, Statistical; Dyskinesia, Drug-Induced; Female; Levodopa; Male; MPTP Poisoning; Nicotine; Nicotinic Agonists; Parkinson Disease, Secondary; Saimiri | 2013 |
Nicotinic receptor agonists reduce L-DOPA-induced dyskinesias in a monkey model of Parkinson's disease.
Topics: Animals; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Levodopa; Male; Nicotine; Nicotinic Agonists; Parkinson Disease; Receptors, Nicotinic; Saimiri | 2013 |
Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using Parkinsonian α6(∗) nAChR gain-of-function mice.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Levodopa; Male; Mice; Mice, Transgenic; Nicotine; Nicotinic Agonists; Oxidopamine; Parkinsonian Disorders; Protein Binding; Receptors, Nicotinic | 2015 |
Optogenetic activation of striatal cholinergic interneurons regulates L-dopa-induced dyskinesias.
Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Dyskinesia, Drug-Induced; Interneurons; Levodopa; Mice; Neostriatum; Nicotine; Nicotinic Agonists; Optogenetics | 2016 |
Patient-driven N-of-1 in Parkinson's Disease. Lessons Learned from a Placebo-controlled Study of the Effect of Nicotine on Dyskinesia.
Topics: Dyskinesias; Female; Humans; Levodopa; Middle Aged; Nicotine; Parkinson Disease; Placebos | 2017 |
Effects of antidyskinetic nicotine treatment on dopamine release in dorsal and ventral striatum.
Topics: Animals; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Levodopa; Mice; Nicotine; Nicotinic Agonists; Synaptosomes | 2018 |
Genetic Knockdown of mGluR5 in Striatal D1R-Containing Neurons Attenuates L-DOPA-Induced Dyskinesia in Aphakia Mice.
Topics: Allosteric Regulation; Animals; Aphakia; Biomarkers; Corpus Striatum; Down-Regulation; Dyskinesia, Drug-Induced; Female; Gene Knockdown Techniques; Levodopa; Male; Mice, Inbred C57BL; Models, Biological; Neurons; Nicotine; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D1 | 2019 |
Dyskinesia and brain-derived neurotrophic factor levels after long-term levodopa and nicotinic receptor agonist treatments in female mice with near-total unilateral dopaminergic denervation.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain; Brain-Derived Neurotrophic Factor; Dopamine; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Furans; Levodopa; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Parkinsonian Disorders; Quinuclidines; Random Allocation | 2018 |
Parkinson's: the weirdest disease.
Topics: Animals; Gambling; Humans; Levodopa; Milk; Nicotine; Parkinson Disease; Risk Factors | 2021 |